List of works - Emma De Fabiani

"The Loss of Golden Touch": Mitochondria-Organelle Interactions, Metabolism, and Cancer

scientific article published on 21 November 2020

A bio-guided approach for the development of a chestnut-based proanthocyanidin-enriched nutraceutical with potential anti-gastritis properties

scientific article published on 18 June 2018

A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis.

scientific article published in May 2005

Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases.

scientific article published on 31 October 2016

Bile acids and their signaling pathways: eclectic regulators of diverse cellular functions.

scientific article published on October 2007

Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease

scientific article published on 12 April 2007

Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle

scientific article

Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis

scientific article published in March 2006

Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation

scientific article published on 7 December 2011

Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis

scientific article

Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes

scientific article published on 01 October 1989

Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes. II.

scientific article

Effect of tauroursodeoxycholate feeding, with or without taurine supplementation on hepatic bile acids and cholesterol metabolism in the hamster

scientific article published on 01 May 1987

Enterodiol and enterolactone modulate the immune response by acting on nuclear factor-kappaB (NF-kappaB) signaling.

scientific article

Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling.

scientific article published on 7 August 2009

Gender-related metabolomics and lipidomics: From experimental animal models to clinical evidence.

scientific article published on 6 November 2017

Identification and characterization of cis-acting elements conferring insulin responsiveness on hamster cholesterol 7alpha-hydroxylase gene promoter.

scientific article published on April 2000

Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

scientific article published on 15 October 2012

Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.

scientific article

Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry

scientific article published on 17 October 2019

LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.

scientific article published on 22 January 2014

LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport.

scientific article published on February 2004

Lack of Sterol Regulatory Element Binding Factor-1c Imposes Glial Fatty Acid Utilization Leading to Peripheral Neuropathy

scientific article published on 26 March 2015

Linking epigenetics to lipid metabolism: focus on histone deacetylases.

scientific article

Lipids in the nervous system: from biochemistry and molecular biology to patho-physiology.

scientific article

Minor Components of Olive Oil Modulate Proatherogenic Adhesion Molecules Involved in Endothelial Activation

Mitochondrial dysfunction increases fatty acid β-oxidation and translates into impaired neuroblast maturation

scientific article published on 31 August 2019

Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy

scientific article published on 04 March 2014

Olive oil phenolic extract regulates interleukin-8 expression by transcriptional and posttranscriptional mechanisms in Caco-2 cells.

scientific article published on 27 April 2015

Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kappaB signaling

scientific article

Plasma lipoproteins and cholesterol metabolism in Yoshida rats: An animal model of spontaneous hyperlipemia

scientific article published on 01 January 1992

Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis

scientific article

Regulation of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7A): prevalence of negative over positive transcriptional control.

scientific article published on September 1996

Sterol-protein interactions in cholesterol and bile acid synthesis.

scientific article published on January 2010

Strawberry tannins inhibit IL-8 secretion in a cell model of gastric inflammation.

scientific article published on 26 July 2016

Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors

scientific article

Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans

scientific article published in August 2001

The effect of etofibrate on cholesterol and bile acid metabolism in the hamster

scientific article published on 01 September 1989

The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

scientific article published on 11 June 2001

The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol.

scientific article published on 07 September 2007

The sirtuin class of histone deacetylases: regulation and roles in lipid metabolism

scientific article published on 03 February 2014

When food meets man: the contribution of epigenetics to health.

scientific article published on 25 May 2010

Zc3h10 is a novel mitochondrial regulator.

scientific article published on 5 March 2018

List of works by Emma De Fabiani

"The Loss of Golden Touch": Mitochondria-Organelle Interactions, Metabolism, and Cancer

A bio-guided approach for the development of a chestnut-based proanthocyanidin-enriched nutraceutical with potential anti-gastritis properties

A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis.

Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases.

Bile acids and their signaling pathways: eclectic regulators of diverse cellular functions.

Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease

Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle

Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis

Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation

Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis

Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes

Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes. II.

Effect of tauroursodeoxycholate feeding, with or without taurine supplementation on hepatic bile acids and cholesterol metabolism in the hamster

Enterodiol and enterolactone modulate the immune response by acting on nuclear factor-kappaB (NF-kappaB) signaling.

Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling.

Gender-related metabolomics and lipidomics: From experimental animal models to clinical evidence.

Identification and characterization of cis-acting elements conferring insulin responsiveness on hamster cholesterol 7alpha-hydroxylase gene promoter.

Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.

Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry

LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.

LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport.

Lack of Sterol Regulatory Element Binding Factor-1c Imposes Glial Fatty Acid Utilization Leading to Peripheral Neuropathy

Linking epigenetics to lipid metabolism: focus on histone deacetylases.

Lipids in the nervous system: from biochemistry and molecular biology to patho-physiology.

Minor Components of Olive Oil Modulate Proatherogenic Adhesion Molecules Involved in Endothelial Activation

Mitochondrial dysfunction increases fatty acid β-oxidation and translates into impaired neuroblast maturation

Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy

Olive oil phenolic extract regulates interleukin-8 expression by transcriptional and posttranscriptional mechanisms in Caco-2 cells.

Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kappaB signaling

Plasma lipoproteins and cholesterol metabolism in Yoshida rats: An animal model of spontaneous hyperlipemia

Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis

Regulation of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7A): prevalence of negative over positive transcriptional control.

Sterol-protein interactions in cholesterol and bile acid synthesis.

Strawberry tannins inhibit IL-8 secretion in a cell model of gastric inflammation.

Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors

Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans

The effect of etofibrate on cholesterol and bile acid metabolism in the hamster

The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol.

The sirtuin class of histone deacetylases: regulation and roles in lipid metabolism

When food meets man: the contribution of epigenetics to health.

Zc3h10 is a novel mitochondrial regulator.