List of works - Yoshitaka Hayashi

9-cis-retinoic acid decreases the level of its cognate receptor, retinoid X receptor, through acceleration of the turnover

scientific article published on 01 July 1999

A Japanese family with autosomal dominant growth hormone deficiency

scientific article published on 01 August 1999

A Splicing Variant of Steroid Receptor Coactivator-1 (SRC-1E): The Major Isoform of SRC-1 to Mediate Thyroid Hormone Action ⬇️

scientific article published on July 9, 1997

A case with isolated growth hormone deficiency caused by compound heterozygous mutations in GH-1: a novel missense mutation in the initiation codon and a 7.6kb deletion

scientific article published on 13 March 2007

A mouse model of resistance to thyroid hormone produced by somatic gene transfer of a mutant thyroid hormone receptor

scientific article

A new point mutation (C446R) in the thyroid hormone receptor-beta gene of a family with resistance to thyroid hormone

scientific article published in May 1994

A nonsense mutation (E72X) in growth hormone releasing hormone receptor (GHRHR) gene is the major cause of familial isolated growth hormone deficiency in Western region of India: founder effect suggested by analysis of dinucleotide repeat polymorphi

scientific article published on October 2004

A novel Caspr mutation causes the shambling mouse phenotype by disrupting axoglial interactions of myelinated nerves

scientific journal article

A novel large-scale production system for modified basement membrane matrices using gene-swapped parietal endoderm cells

scientific article published on 28 November 2005

A novel mutation at the donor splice site of intron 3 of the GH-I gene in a patient with isolated growth hormone deficiency

scientific article

A rare case of resistance to thyroid hormone coexisting with Graves' disease

scientific article published on 01 October 2011

A role for thyroid hormone transporters in transcriptional regulation by thyroid hormone receptors

scientific article published on 23 January 2003

Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.

scientific article published on 30 March 2011

Activation of the RhoB signaling pathway by thyroid hormone receptor β in thyroid cancer cells

scientific article published on 30 December 2014

An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families

scientific article published on 01 July 1994

Aristaless-related homeobox plays a key role in hyperplasia of the pancreas islet α-like cells in mice deficient in proglucagon-derived peptides

scientific article

Brief report: resistance to thyrotropin caused by mutations in the thyrotropin-receptor gene

scientific article

Carbohydrate-induced secretion of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1

scientific article

Carbohydrate-induced weight gain models for diabetes research: contribution of incretins and parasympathetic signal

scientific article published on 02 July 2020

Chronic Hyponatremia Causes Neurologic and Psychologic Impairments

scientific article published on 16 September 2015

Dominant inheritance of resistance to thyroid hormone not linked to defects in the thyroid hormone receptor alpha or beta genes may be due to a defective cofactor

scientific article published on 01 December 1996

Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides.

scientific article published on 25 October 2012

Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin

scientific article published on 06 April 2016

Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K cells in response to fat ingestion

article by Kimitaka Shibue et al published 1 April 2015 in American Journal of Physiology - Endocrinology and Metabolism

Fertility and pregnancy-associated ß-cell proliferation in mice deficient in proglucagon-derived peptides

scientific article

Functional adenosine triphosphate-sensitive potassium channel is required in high-carbohydrate diet-induced increase in β-cell mass.

scientific article

Glucagon is essential for adaptive thermogenesis in brown adipose tissue

scientific article published on 20 June 2014

Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in liver

scientific article published on 07 June 2020

Glucocorticoids increase retinoid-X receptor alpha (RXRalpha) expression and enhance thyroid hormone action in primary cultured rat hepatocytes

scientific article published on 01 February 1999

Glutaminostatin: Another facet of glucagon as a regulator of plasma amino acid concentrations

scientific article published on 25 July 2019

Hyperthyroidism due to thyroid-stimulating hormone secretion after surgery for Cushing's syndrome: a novel cause of the syndrome of inappropriate secretion of thyroid-stimulating hormone

scientific article published on 13 May 2013

Identification and recombinant production of human laminin alpha4 subunit splice variants

scientific article (publication date: 6 December 2002)

Identification of a novel myosin-Va mutation in an ataxic mutant rat, dilute-opisthotonus

scientific journal article

Identification of an upstream enhancer in the mouse laminin alpha 1 gene defining its high level of expression in parietal endoderm cells

scientific article published on 7 January 2003

Identification of genes differentially expressed in mouse fetuses from streptozotocin-induced diabetic pregnancy by cDNA subtraction.

scientific article

Inactivation of the Rcan2 gene in mice ameliorates the age- and diet-induced obesity by causing a reduction in food intake

scientific article

Influence of dietary iodine deficiency on the thyroid gland in Slc26a4-null mutant mice.

scientific article

Insertion of an intracisternal A particle retrotransposon element in plasma membrane calcium ATPase 2 gene attenuates its expression and produces an ataxic phenotype in joggle mutant mice.

scientific article

Isolated growth hormone deficiency in two siblings because of paternal mosaicism for a mutation in the GH1 gene

scientific article published in March 2012

KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state

scientific article published on 02 June 2014

Long-term amiodarone treatment causes cardioselective hypothyroid-like alteration in gene expression profile

scientific article published on 6 October 2007

Low temperature-induced circulating triiodothyronine accelerates seasonal testicular regression

scientific article

Mapping of jog locus to the region between D6Mit104 and D6Mit336 on mouse chromosome 6

scientific article published on 01 October 2007

Metabolic impact of glucagon deficiency ⬇️

scientific article published on October 1, 2011

Mice Deficient in Proglucagon-Derived Peptides Exhibit Glucose Intolerance on a High-Fat Diet but Are Resistant to Obesity

scientific article published on 17 September 2015

Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet {alpha}-cells but not of intestinal L-cells

scientific article

Modification of thyroid hormone and 9-cis retinoic acid signaling by overexpression of their cognate receptors using adenoviral vector

scientific article published on July 1997

Molecular basis of constitutive production of basement membrane components. Gene expression profiles of Engelbreth-Holm-Swarm tumor and F9 embryonal carcinoma cells

scientific article published on 10 September 2003

Molecular cloning of prostaglandin EP3 receptors from canine sensory ganglia and their facilitatory action on bradykinin-induced mobilization of intracellular calcium

scientific article published on 14 December 2006

Molecular cloning of sucrase-isomaltase cDNA in the house musk shrew Suncus murinus and identification of a mutation responsible for isolated sucrase deficiency.

scientific article

Mutations in intron 3 of GH-1 gene associated with isolated GH deficiency type II in three Japanese families

scientific article published on 01 September 1999

Oculocutaneous albinism in Suncus murinus: establishment of a strain and identification of its responsible gene

scientific article published in January 2009

Pancreatic Neuroendocrine Tumors in Mice Deficient in Proglucagon-Derived Peptides.

scientific article published on 20 July 2015

Possible involvement of BRAFV600E in altered gene expression in papillary thyroid cancer

scientific article published on 4 February 2009

Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes

scientific article published on 13 March 2009

Regulation of amino acid metabolism and alpha cell proliferation by glucagon

scientific article published on 3 January 2018

Regulation of mesodermal differentiation of mouse embryonic stem cells by basement membranes

scientific article published on 9 August 2007

Remodeling of Hepatic Metabolism and Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides ⬇️

scientific article published on January 1, 2012

Resistance to Thyroid Hormone Complicated with Type 2 Diabetes and Cardiomyopathy in a Patient with a TRβ Mutation

scientific article

SOX7 and SOX17 regulate the parietal endoderm-specific enhancer activity of mouse laminin alpha1 gene

scientific journal article

Selective pituitary resistance to thyroid hormone produced by expression of a mutant thyroid hormone receptor beta gene in the pituitary gland of transgenic mice

scientific article published on April 1998

Sensory and motor physiological functions are impaired in gastric inhibitory polypeptide receptor-deficient mice

scientific article published on 16 October 2013

Short-Term High-Starch, Low-Protein Diet Induces Reversible Increase in β-cell Mass Independent of Body Weight Gain in Mice

scientific article published on 10 May 2019

Sox7 plays crucial roles in parietal endoderm differentiation in F9 embryonal carcinoma cells through regulating Gata-4 and Gata-6 expression

scientific article

Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo

scientific article published in April 2002

The Sp family of transcription factors regulates the human laminin alpha1 gene in JAR choriocarcinoma cells.

scientific article published on 27 October 2006

Thyroxine-binding globulin: organization of the gene and variants

scientific article published on January 1996

Tumor suppressor p53 is a negative regulator in thyroid hormone receptor signaling pathways

scientific article

Two Mutations in Thyroid Hormone Receptor Beta Gene (P453A and C36Y) in a Family with Resistance to Thyroid Hormone with Comorbid Myotonic Dystrophy

scientific article published on 22 February 2019

Type 1 iodothyronine deiodinase in the house musk shrew (Suncus murinus, Insectivora: Soricidae): cloning and characterization of complementary DNA, unique tissue distribution and regulation by T(3).

scholarly article

List of works by Yoshitaka Hayashi

9-cis-retinoic acid decreases the level of its cognate receptor, retinoid X receptor, through acceleration of the turnover

A Japanese family with autosomal dominant growth hormone deficiency

A Splicing Variant of Steroid Receptor Coactivator-1 (SRC-1E): The Major Isoform of SRC-1 to Mediate Thyroid Hormone Action ⬇️

A case with isolated growth hormone deficiency caused by compound heterozygous mutations in GH-1: a novel missense mutation in the initiation codon and a 7.6kb deletion

A mouse model of resistance to thyroid hormone produced by somatic gene transfer of a mutant thyroid hormone receptor

A new point mutation (C446R) in the thyroid hormone receptor-beta gene of a family with resistance to thyroid hormone

A nonsense mutation (E72X) in growth hormone releasing hormone receptor (GHRHR) gene is the major cause of familial isolated growth hormone deficiency in Western region of India: founder effect suggested by analysis of dinucleotide repeat polymorphi

A novel Caspr mutation causes the shambling mouse phenotype by disrupting axoglial interactions of myelinated nerves

A novel large-scale production system for modified basement membrane matrices using gene-swapped parietal endoderm cells

A novel mutation at the donor splice site of intron 3 of the GH-I gene in a patient with isolated growth hormone deficiency

A rare case of resistance to thyroid hormone coexisting with Graves' disease

A role for thyroid hormone transporters in transcriptional regulation by thyroid hormone receptors

Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.

Activation of the RhoB signaling pathway by thyroid hormone receptor β in thyroid cancer cells

An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families

Aristaless-related homeobox plays a key role in hyperplasia of the pancreas islet α-like cells in mice deficient in proglucagon-derived peptides

Brief report: resistance to thyrotropin caused by mutations in the thyrotropin-receptor gene

Carbohydrate-induced secretion of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1

Carbohydrate-induced weight gain models for diabetes research: contribution of incretins and parasympathetic signal

Chronic Hyponatremia Causes Neurologic and Psychologic Impairments

Dominant inheritance of resistance to thyroid hormone not linked to defects in the thyroid hormone receptor alpha or beta genes may be due to a defective cofactor

Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides.

Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin

Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K cells in response to fat ingestion

Fertility and pregnancy-associated ß-cell proliferation in mice deficient in proglucagon-derived peptides

Functional adenosine triphosphate-sensitive potassium channel is required in high-carbohydrate diet-induced increase in β-cell mass.

Glucagon is essential for adaptive thermogenesis in brown adipose tissue

Glucagon regulates lipolysis and fatty acid oxidation through inositol triphosphate receptor 1 in liver

Glucocorticoids increase retinoid-X receptor alpha (RXRalpha) expression and enhance thyroid hormone action in primary cultured rat hepatocytes

Glutaminostatin: Another facet of glucagon as a regulator of plasma amino acid concentrations

Hyperthyroidism due to thyroid-stimulating hormone secretion after surgery for Cushing's syndrome: a novel cause of the syndrome of inappropriate secretion of thyroid-stimulating hormone

Identification and recombinant production of human laminin alpha4 subunit splice variants

Identification of a novel myosin-Va mutation in an ataxic mutant rat, dilute-opisthotonus

Identification of an upstream enhancer in the mouse laminin alpha 1 gene defining its high level of expression in parietal endoderm cells

Identification of genes differentially expressed in mouse fetuses from streptozotocin-induced diabetic pregnancy by cDNA subtraction.

Inactivation of the Rcan2 gene in mice ameliorates the age- and diet-induced obesity by causing a reduction in food intake

Influence of dietary iodine deficiency on the thyroid gland in Slc26a4-null mutant mice.

Insertion of an intracisternal A particle retrotransposon element in plasma membrane calcium ATPase 2 gene attenuates its expression and produces an ataxic phenotype in joggle mutant mice.

Isolated growth hormone deficiency in two siblings because of paternal mosaicism for a mutation in the GH1 gene

KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state

Long-term amiodarone treatment causes cardioselective hypothyroid-like alteration in gene expression profile

Low temperature-induced circulating triiodothyronine accelerates seasonal testicular regression

Mapping of jog locus to the region between D6Mit104 and D6Mit336 on mouse chromosome 6

Metabolic impact of glucagon deficiency ⬇️

Mice Deficient in Proglucagon-Derived Peptides Exhibit Glucose Intolerance on a High-Fat Diet but Are Resistant to Obesity

Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet {alpha}-cells but not of intestinal L-cells

Modification of thyroid hormone and 9-cis retinoic acid signaling by overexpression of their cognate receptors using adenoviral vector

Molecular basis of constitutive production of basement membrane components. Gene expression profiles of Engelbreth-Holm-Swarm tumor and F9 embryonal carcinoma cells

Molecular cloning of prostaglandin EP3 receptors from canine sensory ganglia and their facilitatory action on bradykinin-induced mobilization of intracellular calcium

Molecular cloning of sucrase-isomaltase cDNA in the house musk shrew Suncus murinus and identification of a mutation responsible for isolated sucrase deficiency.

Mutations in intron 3 of GH-1 gene associated with isolated GH deficiency type II in three Japanese families

Oculocutaneous albinism in Suncus murinus: establishment of a strain and identification of its responsible gene

Pancreatic Neuroendocrine Tumors in Mice Deficient in Proglucagon-Derived Peptides.

Possible involvement of BRAFV600E in altered gene expression in papillary thyroid cancer

Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes

Regulation of amino acid metabolism and alpha cell proliferation by glucagon

Regulation of mesodermal differentiation of mouse embryonic stem cells by basement membranes

Remodeling of Hepatic Metabolism and Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides ⬇️

Resistance to Thyroid Hormone Complicated with Type 2 Diabetes and Cardiomyopathy in a Patient with a TRβ Mutation

SOX7 and SOX17 regulate the parietal endoderm-specific enhancer activity of mouse laminin alpha1 gene

Selective pituitary resistance to thyroid hormone produced by expression of a mutant thyroid hormone receptor beta gene in the pituitary gland of transgenic mice

Sensory and motor physiological functions are impaired in gastric inhibitory polypeptide receptor-deficient mice

Short-Term High-Starch, Low-Protein Diet Induces Reversible Increase in β-cell Mass Independent of Body Weight Gain in Mice

Sox7 plays crucial roles in parietal endoderm differentiation in F9 embryonal carcinoma cells through regulating Gata-4 and Gata-6 expression

Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo

The Sp family of transcription factors regulates the human laminin alpha1 gene in JAR choriocarcinoma cells.

Thyroxine-binding globulin: organization of the gene and variants

Tumor suppressor p53 is a negative regulator in thyroid hormone receptor signaling pathways

Two Mutations in Thyroid Hormone Receptor Beta Gene (P453A and C36Y) in a Family with Resistance to Thyroid Hormone with Comorbid Myotonic Dystrophy

Type 1 iodothyronine deiodinase in the house musk shrew (Suncus murinus, Insectivora: Soricidae): cloning and characterization of complementary DNA, unique tissue distribution and regulation by T(3).