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List of works by José María Valpuesta

3D structure of the influenza virus polymerase complex: localization of subunit domains.

scientific article

A new side opening on prolyl oligopeptidase revealed by electron microscopy.

scientific article published on 25 September 2009

A structural model for the GroEL chaperonin

article

ATP Binding Induces Large Conformational Changes in the Apical and Equatorial Domains of the Eukaryotic Chaperonin Containing TCP-1 Complex

scientific article published in Journal of Biological Chemistry

ATP hydrolysis induces an intermediate conformational state in GroEL

scientific article published on 01 January 1999

Active DNA unwinding dynamics during processive DNA replication.

scientific article

All three chaperonin genes in the archaeon Haloferax volcanii are individually dispensable.

scientific article published in September 2006

Alpha,gamma-peptide nanotube templating of one-dimensional parallel fullerene arrangements

scientific article published on 01 August 2009

An infrared spectroscopic study of specifically deuterated fatty-acyl methyl groups in phosphatidylcholine liposomes

scientific article published in May 1991

An intrinsic-tryptophan-fluorescence study of phage phi 29 connector/nucleic acid interactions

scientific article published on 01 October 1994

Analysis of electron microscope images and electron diffraction patterns of thin crystals of phi 29 connectors in ice.

scientific article published on July 1994

Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin

scientific article (publication date: August 2001)

Arc is a flexible modular protein capable of reversible self-oligomerization

scientific article

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

scientific article published on 7 February 2012

Assembly of archaeal cell division protein FtsZ and a GTPase-inactive mutant into double-stranded filaments.

scientific article

Assisted protein folding at low temperature: evolutionary adaptation of the Antarctic fish chaperonin CCT and its client proteins

scientific article (publication date: 15 April 2014)

Bacterial tubulin distinct loop sequences and primitive assembly properties support its origin from a eukaryotic tubulin ancestor

scientific article

Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms: New structural insights to unravel CCR4-NOT mRNA processing machinery

scientific article published on 9 August 2016

Biochemical Characterization of Symmetric GroEL-GroES Complexes

scientific article published in Journal of Biological Chemistry

Changes in Microtubule Protofilament Number Induced by Taxol Binding to an Easily Accessible Site

scientific article published in Journal of Biological Chemistry

Chaperonins: folding in the hole

scientific article published on 01 August 2001

Chaperonins: two rings for folding

scientific article

Characterization by atomic force microscopy and cryoelectron microscopy of tau polymers assembled in Alzheimer's disease

scientific article published on 01 October 2001

Characterization of ATP and DNA Binding Activities of TrwB, the Coupling Protein Essential in Plasmid R388 Conjugation

scientific article published in Journal of Biological Chemistry

Characterization of an RNA-binding domain in the bacteriophage phi 29 connector

scientific article published on 01 September 1993

Characterization of the structure and self-recognition of the human centrosomal protein NA14: implications for stability and function.

scientific article

Clathrin-coat disassembly illuminates the mechanisms of Hsp70 force generation

scientific article published on August 2016

Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

scientific article

Condensation prevails over B-A transition in the structure of DNA at low humidity

scientific article published on April 2011

Conformational Changes Generated in GroEL during ATP Hydrolysis as Seen by Time-resolved Infrared Spectroscopy

scientific article published in Journal of Biological Chemistry

Conformational changes in the GroEL oligomer during the functional cycle.

scientific article

Constancy of liver lipid composition in two genera of toads after a short-term temperature acclimation

scientific article published on 01 March 1981

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin

scientific article

Crystallographic analysis reveals the 12-fold symmetry of the bacteriophage phi29 connector particle.

scientific article published in August 1998

DNA conformational change induced by the bacteriophage phi 29 connector

scientific article published on November 1992

Detailed architecture of a DNA translocating machine: the high-resolution structure of the bacteriophage phi29 connector particle

scientific article

Different coordination modes of an aryl-substituted hydrotris(pyrazolyl)borate ligand in rhodium and iridium complexes

scholarly article by Salvador Conejero et al published April 2011 in Inorganica Chimica Acta

Dihydrogen Catalysis of the Reversible Formation and Cleavage of CH and NH Bonds of Aminopyridinate Ligands Bound to (η5-C5Me5)IrIII

article by Ana Zamorano et al published 11 December 2014 in Chemistry—A European Journal

Dihydrogen-Catalyzed Reversible Carbon-Hydrogen and Nitrogen-Hydrogen Bond Formation in Organometallic Iridium Complexes

scholarly article by José E. V. Valpuesta et al published 18 June 2012 in Angewandte Chemie International Edition

Divergent Substrate-Binding Mechanisms Reveal an Evolutionary Specialization of Eukaryotic Prefoldin Compared to Its Archaeal Counterpart

scientific article published on 01 January 2007

Domain architecture of the bacteriophage phi29 connector protein

scientific article published on 01 May 1999

Domain topology of human Rasal

scientific article published on 26 September 2017

Dynamics, flexibility, and allostery in molecular chaperonins

scientific article

Effect of the nonionic detergent Triton X-100 on mitochondrial succinate-oxidizing enzymes

scientific article published on 01 February 1984

Effects of the Inter-ring Communication in GroEL Structural and Functional Asymmetry

scientific article published in Journal of Biological Chemistry

Electron microscopy: the coming of age of a structural biology technique

scientific article published on 30 June 2015

Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis

scientific article published on 15 July 2019

Energetics and geometry of FtsZ polymers: nucleated self-assembly of single protofilaments

scientific article

Engineering protein assemblies with allosteric control via monomer fold-switching

scientific article published on 13 December 2019

Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations

scientific article

Experimental and computational studies on the iridium activation of aliphatic and aromatic C-H bonds of alkyl aryl ethers and related molecules

scientific article published in September 2009

Expression, Functional Characterization, and Preliminary Crystallization of the Cochaperone Prefoldin from the Thermophilic Fungus

scientific article published on 19 August 2018

Ferritin is associated with the aberrant tau filaments present in progressive supranuclear palsy

scientific article published on June 1998

Folding, stability and polymerization properties of FtsZ chimeras with inserted tubulin loops involved in the interaction with the cytosolic chaperonin CCT and in microtubule formation

scientific article published on 18 December 2004

Globular Aggregates Stemming from the Self-Assembly of an Amphiphilic N-Annulated Perylene Bisimide in Aqueous Media

scientific article published in 2021

Gold nanoparticles generated in ethosome bilayers, as revealed by cryo-electron-tomography

scientific article published in March 2009

GroEL stability and function. Contribution of the ionic interactions at the inter-ring contact sites

scientific article

GroEL under Heat-Shock

scientific article published in Journal of Biological Chemistry

HYDROMIC: prediction of hydrodynamic properties of rigid macromolecular structures obtained from electron microscopy images

scientific article published on 01 October 2001

High resolution atomic force microscopy of double-stranded RNA.

scientific article

Hsp70 - a master regulator in protein degradation

scientific article

Hsp70 chaperone: a master player in protein homeostasis

IHF protein inhibits cleavage but not assembly of plasmid R388 relaxosomes

scientific article published on 01 March 1999

Identification of Key Amino Acid Residues Modulating Intracellular and In vitro Microcin E492 Amyloid Formation

scientific article published on 28 January 2016

Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes

scientific article published on 8 September 2011

Infrared spectroscopic studies of detergent-solubilized uncoupling protein from brown-adipose-tissue mitochondria

scientific article published on 01 February 1990

Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity

scientific article

Interactions of the HIV-1 fusion peptide with large unilamellar vesicles and monolayers. A cryo-TEM and spectroscopic study

scientific article published on July 2000

Interbilayer lipid mixing induced by the human immunodeficiency virus type-1 fusion peptide on large unilamellar vesicles: the nature of the nonlamellar intermediates

scientific article published on December 1999

Ionic interactions at both inter-ring contact sites of GroEL are involved in transmission of the allosteric signal: a time-resolved infrared difference study

scientific article published on 4 August 2005

Large Terminase Conformational Change Induced by Connector Binding in Bacteriophage T7

scientific article

Lipid-protein interactions. The mitochondrial complex III-phosphatidylcholine-water system

scientific article published in July 1988

Lipids of marine teleost fish (Teleostei)

scientific article published on 01 October 1980

Manipulation of single polymerase-DNA complexes: a mechanical view of DNA unwinding during replication

scientific article published on 8 August 2012

Maturation of phage T7 involves structural modification of both shell and inner core components

scientific article

Mechanical identities of RNA and DNA double helices unveiled at the single-molecule level

scientific article published on 24 December 2012

Mechanical properties of high-G.C content DNA with a-type base-stacking

scientific article published on April 2011

Mechanical stability of low-humidity single DNA molecules

scientific article published on 23 October 2011

Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase

scientific article

Microcin e492 amyloid formation is retarded by posttranslational modification

scientific article

Modulation of the Hsp90 chaperone cycle by a stringent client protein

scientific article published on 6 March 2014

Modulation of the chaperone DnaK allosterism by the nucleotide exchange factor GrpE.

scientific article published on 4 March 2015

Molecular Rearrangements Involved in the Capsid Shell Maturation of Bacteriophage T7

scientific article

Molecular chaperones: functional mechanisms and nanotechnological applications

scientific article published in July 2016

Molecular clamp mechanism of substrate binding by hydrophobic coiled-coil residues of the archaeal chaperone prefoldin

scholarly article

Molecular determinants of the ATP hydrolysis asymmetry of the CCT chaperonin complex

scholarly article by Monica Chagoyen published in February 2014

Note to the Paper by Guasch et al. (2002) Detailed Architecture of a DNA Translocating Machine: The High-resolution Structure of the Bacteriophage ϕ29 Connector Particle

scientific article published on August 2002

Nucleoplasmin Binds Histone H2A-H2B Dimers through Its Distal Face

scientific article

Partial Occlusion of Both Cavities of the Eukaryotic Chaperonin with Antibody Has No Effect upon the Rates of β-Actin or α-Tubulin Folding

scientific article published in Journal of Biological Chemistry

PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates

scientific article

Phosphoinositide 3-kinase beta controls replication factor C assembly and function

scientific article published on 21 November 2012

Phosphoinositide 3-kinase beta protects nuclear envelope integrity by controlling RCC1 localization and Ran activity

scientific article published on 27 October 2014

Phosphorylation dependence and stoichiometry of the complex formed by tyrosine hydroxylase and 14-3-3γ.

scientific article

Physiological state of submitochondrial particles and their susceptibility to Triton X-100

scientific article published on 01 February 1984

Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT

scientific article (publication date: August 2001)

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction

scientific article published on 01 September 1996

Prediction of the structure of GroES and its interaction with GroEL.

scientific article

Prefoldin 5 is required for normal sensory and neuronal development in a murine model

scientific article

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding

scientific article

Purification and functional characterization of p16, the ATPase of the bacteriophage Phi29 packaging machinery.

scientific article published on November 2001

Purification and properties of TrwB, a hexameric, ATP-binding integral membrane protein essential for R388 plasmid conjugation

scientific article

Purification, crystallization and preliminary X-ray diffraction studies of the bacteriophage phi29 connector particle

scientific article

RNA-mediated specificity of DNA packaging into hybrid lambda/phi 29 proheads

scientific article

Recognition of membrane-bound fusion-peptide/MPER complexes by the HIV-1 neutralizing 2F5 antibody: implications for anti-2F5 immunogenicity

scientific article

Resorcinarenes with 2-benzimidazolone bridges: self-aggregation, self-assembled dimeric capsules, and guest encapsulation.

scientific article

Reversible interaction of beta-actin along the channel of the TCP-1 cytoplasmic chaperonin

scientific article published on July 1994

Rhodium and iridium olefin complexes with bulky cyclopentadienyl and hydrotris(pyrazolyl)borate ligands

scholarly article by Salvador Conejero et al published September 2009 in Inorganica Chimica Acta

Role of glycosaminoglycans in determining the helicity of paired helical filaments

scientific article published on October 1997

Role of the amino terminal domain in GroES oligomerization

scientific article published on 01 January 1997

Role of the amino-terminal domain of bacteriophage phi 29 connector in DNA binding and packaging

scientific article published on 01 May 1992

SADB phosphorylation of gamma-tubulin regulates centrosome duplication

scientific journal article

Salt bridges at the inter-ring interface regulate the thermostat of GroEL.

scientific article

Segregated ordered lipid phases and protein-promoted membrane cohesivity are required for pulmonary surfactant films to stabilize and protect the respiratory surface.

scientific article published on January 2013

Selection of antibody probes to correlate protein sequence domains with their structural distribution

scientific article published on April 1999

Sequential action of ATP-dependent subunit conformational change and interaction between helical protrusions in the closure of the built-in lid of group II chaperonins

scientific article published on 13 October 2008

Single centrosome manipulation reveals its electric charge and associated dynamic structure.

scientific article published in August 2009

Size-selective recognition of gold nanoparticles by a molecular chaperone

Stress-induced recrystallization of a protein crystal by electron irradiation

scientific article published in Nature

Structural Analysis of the Bacteriophage T3 Head-to-Tail Connector

scientific article published on 01 August 2000

Structural Characterization of the Bacteriophage T7 Tail Machinery

scientific article

Structural analysis of the interactions between hsp70 chaperones and the yeast DNA replication protein Orc4p.

scientific article

Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly

scientific article published on 28 June 2019

Structural characterization of microcin E492 amyloid formation: Identification of the precursors

scientific article published on 07 March 2012

Structural characterization of the NAP; the major adhesion complex of the human pathogen Mycoplasma genitalium.

scientific article published on 3 July 2017

Structural characterization of the TCR complex by electron microscopy

scientific article

Structural characterization of the substrate transfer mechanism in Hsp70/Hsp90 folding machinery mediated by Hop.

scientific article

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.

scientific article published on 8 April 2015

Structural comparison of prokaryotic and eukaryotic chaperonins.

scientific article published in January 2001

Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

scientific article published on 01 July 2019

Structural insights into the chaperone activity of the 40-kDa heat shock protein DnaJ: binding and remodeling of a native substrate

scientific article

Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation

scientific article published on 10 January 2022

Structure and function of a protein folding machine: the eukaryotic cytosolic chaperonin CCT.

scientific article

Structure and non-structure of centrosomal proteins.

scientific article

Structure and thermal denaturation of crystalline and noncrystalline cytochrome oxidase as studied by infrared spectroscopy

scientific article published on September 1994

Structure of GroEL in complex with an early folding intermediate of alanine glyoxylate aminotransferase.

scientific article published on 7 January 2010

Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT.

scientific article

Structure of the Hsp110:Hsc70 nucleotide exchange machine

scientific article

Structure of the complex between the cytosolic chaperonin CCT and phosducin-like protein.

scholarly article

Structure of the connector of bacteriophage T7 at 8A resolution: structural homologies of a basic component of a DNA translocating machinery

scientific article published on April 2005

Structure of viral connectors and their function in bacteriophage assembly and DNA packaging

scientific article published on May 1994

Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly

scientific article

The architecture of the Schizosaccharomyces pombe CCR4-NOT complex

scientific article published on 25 January 2016

The broadly neutralizing anti-human immunodeficiency virus type 1 4E10 monoclonal antibody is better adapted to membrane-bound epitope recognition and blocking than 2F5.

scientific article published on 2 July 2008

The chaperonin CCT controls T cell receptor-driven 3D configuration of centrioles

scientific article published on 02 December 2020

The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction.

scientific article published on 19 January 2017

The chaperonin CCT promotes the formation of fibrillar aggregates of γ-tubulin

scientific article published on 12 January 2018

The cochaperone CHIP marks Hsp70- and Hsp90-bound substrates for degradation through a very flexible mechanism

scientific article published on 25 March 2019

The formation of symmetrical GroEL-GroES complexes in the presence of ATP.

scientific article

The hexameric structure of a conjugative VirB4 protein ATPase provides new insights for a functional and phylogenetic relationship with DNA translocases

scientific article published on 3 October 2012

The inter-ring arrangement of the cytosolic chaperonin CCT

scientific article

The interaction of DNA with bacteriophage phi 29 connector: a study by AFM and TEM

scientific article published on 01 May 1996

The intrinsically disordered distal face of nucleoplasmin recognizes distinct oligomerization states of histones.

scientific article published on 10 October 2013

The structure of CCT-Hsc70 NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin.

scientific article published on 27 July 2008

The structure of a biologically active influenza virus ribonucleoprotein complex

scientific article (publication date: June 2009)

The structure of native influenza virion ribonucleoproteins

scientific article

The structure of the complex between α-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism

scientific article

The substrate recognition mechanisms in chaperonins

scientific article published on March 2004

The three-dimensional structure of a DNA translocating machine at 10 A resolution

scientific article published in March 1999

The three-dimensional structure of an eukaryotic glutamine synthetase: Functional implications of its oligomeric structure

scientific article published on 21 June 2006

The yeast THO complex forms a 5-subunit assembly that directly interacts with active chromatin

scientific article published on July 2012

Three-dimensional reconstruction of a recombinant influenza virus ribonucleoprotein particle

scientific article published on April 2001

Three-dimensional structure of T3 connector purified from overexpressing bacteria

scientific article published on March 1992

Topology of the components of the DNA packaging machinery in the phage phi29 prohead.

scientific article published in May 2000

Tryptophan fluorescence of mitochondrial complex III reconstituted in phosphatidylcholine bilayers

scientific article published on 01 September 1987

Yeast mitochondrial RNAP conformational changes are regulated by interactions with the mitochondrial transcription factor

scientific article

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