List of works - Peter R Schofield

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

scientific article

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

scientific article

Common genetic variants influence human subcortical brain structures

scientific article

Structural and functional basis for GABAA receptor heterogeneity.

scientific article published in September 1988

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety.

scientific article published on 20 January 2009

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations

scientific journal article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder

scientific article

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

scientific article

Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder

scientific article

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease

scientific article

The glycine receptor

scientific article

Genome-wide association study reveals two new risk loci for bipolar disorder

scientific article (publication date: 11 March 2014)

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

scientific article

Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis

scientific article

Life events, first depression onset and the serotonin transporter gene

scientific article published in March 2006

Specific and common genes implicated across major mental disorders: a review of meta-analysis studies

scientific article

Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative

scientific article published in October 2007

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

scientific article published on 2 May 2017

GSK3B polymorphisms alter transcription and splicing in Parkinson's disease

scientific journal article

Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: expansion of the disease phenotype caused by tau gene mutations.

scientific article published on May 2000

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network

scientific article (publication date: October 2012)

Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase).

scientific article

A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse

scientific article

Ligand-gated ion channels: mechanisms underlying ion selectivity

scientific article published in October 2004

Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists

scientific article published on January 1995

Frontotemporal dementia and its subtypes: a genome-wide association study

scientific article

Molecular cloning and expression of a chloride ion channel of cell nuclei

scientific article

Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

scientific article

Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits

scientific article

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

scientific article published on 21 January 2016

Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia.

scientific article

Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease.

scientific article published on November 2010

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

scientific article

Tau haplotypes regulate transcription and are associated with Parkinson's disease.

scientific article published on March 2004

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Impaired default network functional connectivity in autosomal dominant Alzheimer disease

scientific article published on 24 July 2013

Functional chloride channels by mammalian cell expression of rat glycine receptor subunit

scientific article (publication date: May 1989)

Genetics of dementia

scientific article published in The Lancet

The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder

scientific article

Partial volume correction in quantitative amyloid imaging

scientific article published on 5 December 2014

Molecular cloning and amino acid sequence of rat enkephalinase

scientific journal article

Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.

scientific article published on June 1995

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

scientific article published on 21 January 2019

Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial.

scientific article

Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification

scientific article

List of works by Peter R Schofield

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

Common genetic variants influence human subcortical brain structures

Structural and functional basis for GABAA receptor heterogeneity.

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety.

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations

Analysis of shared heritability in common disorders of the brain

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease

The glycine receptor

Genome-wide association study reveals two new risk loci for bipolar disorder

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis

Life events, first depression onset and the serotonin transporter gene

Specific and common genes implicated across major mental disorders: a review of meta-analysis studies

Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

GSK3B polymorphisms alter transcription and splicing in Parkinson's disease

Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: expansion of the disease phenotype caused by tau gene mutations.

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network

Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase).

A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse

Ligand-gated ion channels: mechanisms underlying ion selectivity

Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists

Frontotemporal dementia and its subtypes: a genome-wide association study

Molecular cloning and expression of a chloride ion channel of cell nuclei

Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia.

Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease.

Novel genetic loci underlying human intracranial volume identified through genome-wide association

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

Tau haplotypes regulate transcription and are associated with Parkinson's disease.

Novel genetic loci associated with hippocampal volume

Impaired default network functional connectivity in autosomal dominant Alzheimer disease

Functional chloride channels by mammalian cell expression of rat glycine receptor subunit

Genetics of dementia

The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder

Partial volume correction in quantitative amyloid imaging

Molecular cloning and amino acid sequence of rat enkephalinase

Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial.

Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification