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List of works by Eva Hedlund

A tyrosine hydroxylase-yellow fluorescent protein knock-in reporter system labeling dopaminergic neurons reveals potential regulatory role for the first intron of the rodent tyrosine hydroxylase gene.

scientific article published on 31 July 2006

ALS model glia can mediate toxicity to motor neurons derived from human embryonic stem cells.

scientific article published on December 2008

Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis

scientific article published on 11 December 2020

Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

scholarly article

CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells

scientific article published on 22 November 2017

Cell therapy and stem cells in animal models of motor neuron disorders.

scientific article

Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy.

scientific article published on 04 September 2012

Cellular therapy to target neuroinflammation in amyotrophic lateral sclerosis ⬇️

scientific article published on 08 October 2013

Cross-disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology.

scientific article published on 26 October 2015

Cytochrome P450 in the brain: 2B or not 2B.

scientific article published in March 1998

Cytochrome P450 in the brain; a review.

scientific article

Cytochrome P450 in the breast and brain: role in tissue-specific activation of xenobiotics

scientific article published in May 1997

Cytochrome P4502D4 in the brain: specific neuronal regulation by clozapine and toluene

scientific article published in August 1996

Differential Pax6 promoter activity and transcript expression during forebrain development

scientific article

Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS.

scientific article published on 16 May 2016

Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons.

scientific article

Directed midbrain and spinal cord neurogenesis from pluripotent stem cells to model development and disease in a dish

scientific article

Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors

scientific article published on June 2016

Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease

scientific article published on 03 April 2008

Extrahepatic cytochrome P450: role in in situ toxicity and cell-specific hormone sensitivity

scientific article published in January 1998

Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling

article

Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation

scientific article published in June 2006

Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection

scientific article

Intact single muscle fibres from SOD1G93A amyotrophic lateral sclerosis mice display preserved specific force, fatigue resistance and training-like adaptations

scientific article published on 22 May 2019

L1 CAM expression is increased surrounding the lesion site in rats with complete spinal cord transection as neonates

scientific article published in August 2005

LCM-Seq: A Method for Spatial Transcriptomic Profiling Using Laser Capture Microdissection Coupled with PolyA-Based RNA Sequencing

scientific article published in January 2018

LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy

scientific article published on 20 August 2020

Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis

scientific article

Motor neurons with differential vulnerability to degeneration show distinct protein signatures in health and ALS.

scientific article published on 16 February 2015

Neuronal cell replacement in Parkinson's disease.

scientific article published on October 2009

Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation

scientific article

Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation

scientific article published on 7 November 2017

Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration.

scientific article

Region-specific cell grafting into cervical and lumbar spinal cord in rat: a qualitative and quantitative stereological study.

scientific article

Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations

scientific article published on 18 January 2007

Single-cell RNA sequencing: Technical advancements and biological applications

scientific article

Spatial transcriptomics and in silico random pooling identify novel dopamine neuron subtype markers

scholarly article published 31 May 2018

Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development

scientific journal article

The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons.

scientific article published on February 2005

The protective effects of beta-lactam antibiotics in motor neuron disorders ⬇️

scientific article (publication date: September 2011)

Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells

scientific article

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