List of works - Jacqueline A. Wilce

1H NMR structural study of free and template-linked antigenic peptide representing the C-terminal region of the heavy chain of influenza virus hemagglutinin

scientific article published in January 1996

1H NMR studies of peptide fragments from the N-terminus of chicken and human transthyretin.

scientific article

1H NMR studies of the effects of glycosylation on the C-terminal pentapeptide of peptide T.

scientific article

1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy

scientific article published on 01 June 1999

A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4

scientific article

A functional comparison of the venom of three Australian jellyfish--Chironex fleckeri, Chiropsalmus sp., and Carybdea xaymacana--on cytosolic Ca2+, haemolysis and Artemia sp. lethality

scientific article published in February 2005

Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting

scientific article published in February 2005

Benzopyrazine derivatives: A novel class of growth factor receptor bound protein 7 antagonists

scientific article published on 19 October 2010

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

scientific article

Conformational stability studies of a stapled hexa-β3-peptide library

scientific article

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

scientific article published on 23 March 2010

Context-dependent role of Grb7 in HER2+ve and triple-negative breast cancer cell lines

scientific article published on 25 January 2014

Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides ⬇️

scientific article published on February 16, 2012

Cooperative interplay of let-7 mimic and HuR with MYC RNA.

scientific article

Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target

scientific article

Design and testing of bicyclic inhibitors of Grb7--are two cycles better than one?

scientific article published in September 2013

Different modes of interaction by TIAR and HuR with target RNA and DNA

scientific article

Direct Interaction between Calmodulin and the Grb7 RA-PH Domain

scientific article published on 17 February 2020

Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target

scientific article published on 30 October 2017

Distinct binding properties of TIAR RRMs and linker region

scientific article published on April 2013

Domain-specific phosphomimetic mutation allows dissection of different protein kinase C (PKC) isotype-triggered activities of the RNA binding protein HuR.

scientific article published on 23 August 2013

Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR.

scientific article

Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26

scientific article published on 17 March 2020

Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation

scientific article

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

scientific article

Identification of PLA(2) and alpha-neurotoxin proteins in the venom of Pseudonaja affinis (dugite).

scientific article

Insight into the Selectivity of the G7-18NATE Inhibitor Peptide for the Grb7-SH2 Domain Target

scientific article published on 26 September 2017

Interaction of the non‐phosphorylated peptide G7‐18NATE with Grb7‐SH2 domain requires phosphate for enhanced affinity and specificity ⬇️

scientific article published on January 1, 2012

Interaction of the replication terminator protein of Bacillus subtilis with DNA probed by NMR spectroscopy

scientific article

Mutation and crystallization of the first KH domain of human polycytosine-binding protein 1 (PCBP1) in complex with DNA ⬇️

scientific article published on September 30, 2011

NMR analysis of G7-18NATE, a nonphosphorylated cyclic peptide inhibitor of the Grb7 adapter protein.

scientific article

Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide ⬇️

scientific article published on November 26, 2010

Preparation of crystals for characterizing the Grb7 SH2 domain before and after complex formation with a bicyclic peptide antagonist

scientific article published on 21 January 2014

Prokaryotic origins for the mitochondrial alternative oxidase and plastid terminal oxidase nuclear genes

article

RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility

scientific article

RNA recognition and stress granule formation by TIA proteins

scientific article

Role of interfacial hydrophobic residues in the stabilization of the leucine zipper structures of the transcription factors c-Fos and c-Jun

scientific article

Shortened Penetratin Cell-Penetrating Peptide Is Insufficient for Cytosolic Delivery of a Grb7 Targeting Peptide

scientific article published on 23 February 2017

Site-directed mutants of RTP of Bacillus subtilis and the mechanism of replication fork arrest.

scientific article published in March 1999

Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression

scientific article

Structural characterisation of Staphylococcus aureus biotin protein ligase and interaction partners: An antibiotic target.

scientific article published on 5 April 2013

Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: an antibiotic target

scientific article

Studies of protein-ligand interactions by NMR

scientific article published on 01 January 1997

Supramolecular self-assembly of N-acetyl-capped β-peptides leads to nano- to macroscale fiber formation.

scientific article published on 19 June 2013

Synthesis and structural analysis of the N-terminal domain of the thyroid hormone-binding protein transthyretin

scientific article

Synthesis of Stapled β3-Peptides through Ring-Closing Metathesis

scientific article published on 01 October 2009

Synthesis of an analog of the thyroid hormone-binding protein transthyretin via regioselective chemical ligation

scientific article

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

scientific article published on May 2001

The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in . e

scientific article published on 21 December 2018

The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain

scientific article

The crystal structure of DehI reveals a new alpha-haloacid dehalogenase fold and active-site mechanism

scientific article

The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents

scientific article published on 17 December 2012

The impact of cell-penetrating peptides on membrane bilayer structure during binding and insertion

scientific article published on 07 May 2016

The intracellular and nuclear-targeted delivery of an antiandrogen drug by carrier peptides

scientific article

Toxins not neutralized by brown snake antivenom

scientific article published on 26 October 2005

Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.

scientific article published on 03 June 2016

Uptake of a cell permeable G7-18NATE contruct into cells and binding with the Grb-7-SH2 domain

scientific article published on January 2011

pH-Dependent Changes in the in Vitro Ligand-Binding Properties and Structure of Human Clusterin

scientific article published on 01 February 2000

List of works by Jacqueline A. Wilce

1H NMR structural study of free and template-linked antigenic peptide representing the C-terminal region of the heavy chain of influenza virus hemagglutinin

1H NMR studies of peptide fragments from the N-terminus of chicken and human transthyretin.

1H NMR studies of the effects of glycosylation on the C-terminal pentapeptide of peptide T.

1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy

A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4

A functional comparison of the venom of three Australian jellyfish--Chironex fleckeri, Chiropsalmus sp., and Carybdea xaymacana--on cytosolic Ca2+, haemolysis and Artemia sp. lethality

Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting

Benzopyrazine derivatives: A novel class of growth factor receptor bound protein 7 antagonists

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

Conformational stability studies of a stapled hexa-β3-peptide library

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Context-dependent role of Grb7 in HER2+ve and triple-negative breast cancer cell lines

Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides ⬇️

Cooperative interplay of let-7 mimic and HuR with MYC RNA.

Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target

Design and testing of bicyclic inhibitors of Grb7--are two cycles better than one?

Different modes of interaction by TIAR and HuR with target RNA and DNA

Direct Interaction between Calmodulin and the Grb7 RA-PH Domain

Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target

Distinct binding properties of TIAR RRMs and linker region

Domain-specific phosphomimetic mutation allows dissection of different protein kinase C (PKC) isotype-triggered activities of the RNA binding protein HuR.

Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR.

Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26

Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

Identification of PLA(2) and alpha-neurotoxin proteins in the venom of Pseudonaja affinis (dugite).

Insight into the Selectivity of the G7-18NATE Inhibitor Peptide for the Grb7-SH2 Domain Target

Interaction of the non‐phosphorylated peptide G7‐18NATE with Grb7‐SH2 domain requires phosphate for enhanced affinity and specificity ⬇️

Interaction of the replication terminator protein of Bacillus subtilis with DNA probed by NMR spectroscopy

Mutation and crystallization of the first KH domain of human polycytosine-binding protein 1 (PCBP1) in complex with DNA ⬇️

NMR analysis of G7-18NATE, a nonphosphorylated cyclic peptide inhibitor of the Grb7 adapter protein.

Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide ⬇️

Preparation of crystals for characterizing the Grb7 SH2 domain before and after complex formation with a bicyclic peptide antagonist

Prokaryotic origins for the mitochondrial alternative oxidase and plastid terminal oxidase nuclear genes

RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility

RNA recognition and stress granule formation by TIA proteins

Role of interfacial hydrophobic residues in the stabilization of the leucine zipper structures of the transcription factors c-Fos and c-Jun

Shortened Penetratin Cell-Penetrating Peptide Is Insufficient for Cytosolic Delivery of a Grb7 Targeting Peptide

Site-directed mutants of RTP of Bacillus subtilis and the mechanism of replication fork arrest.

Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression

Structural characterisation of Staphylococcus aureus biotin protein ligase and interaction partners: An antibiotic target.

Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: an antibiotic target

Studies of protein-ligand interactions by NMR

Supramolecular self-assembly of N-acetyl-capped β-peptides leads to nano- to macroscale fiber formation.

Synthesis and structural analysis of the N-terminal domain of the thyroid hormone-binding protein transthyretin

Synthesis of Stapled β3-Peptides through Ring-Closing Metathesis

Synthesis of an analog of the thyroid hormone-binding protein transthyretin via regioselective chemical ligation

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in . e

The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain

The crystal structure of DehI reveals a new alpha-haloacid dehalogenase fold and active-site mechanism

The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents

The impact of cell-penetrating peptides on membrane bilayer structure during binding and insertion

The intracellular and nuclear-targeted delivery of an antiandrogen drug by carrier peptides

Toxins not neutralized by brown snake antivenom

Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.

Uptake of a cell permeable G7-18NATE contruct into cells and binding with the Grb-7-SH2 domain

pH-Dependent Changes in the in Vitro Ligand-Binding Properties and Structure of Human Clusterin