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List of works by David I. Leavesley

A chimeric vitronectin: IGF-I protein supports feeder-cell-free and serum-free culture of human embryonic stem cells

article

A fence barrier method of leading edge cell capture for explorative biochemical research.

scientific article

A fragment of the LG3 peptide of endorepellin is present in the urine of physically active mining workers: a potential marker of physical activity

scientific article (publication date: 2012)

Adult human articular chondrocytes in a microcarrier-based culture system: expansion and redifferentiation

article

Antagonists of IGF:Vitronectin Interactions Inhibit IGF-I-Induced Breast Cancer Cell Functions

scientific article

Application of "macromolecular crowding" in vitro to investigate the naphthoquinones shikonin, naphthazarin and related analogues for the treatment of dermal scars

scientific article published on 10 July 2019

Association of Extracellular Membrane Vesicles with Cutaneous Wound Healing.

scientific article published on May 2017

Characteristics and roles of extracellular vesicles released by epidermal keratinocytes

scientific article published on 09 September 2019

Chimeric vitronectin:insulin-like growth factor proteins enhance cell growth and migration through co-activation of receptors

scientific article published on October 2007

Deep Sequencing MicroRNAs from Extracellular Membrane Vesicles Revealed the Association of the Vesicle Cargo with Cellular Origin

scientific article published on 08 February 2020

Development of a three-dimensional human skin equivalent wound model for investigating novel wound healing therapies

scientific article published on 01 October 2010

Development of defined media for the serum-free expansion of primary keratinocytes and human embryonic stem cells.

scientific article published in September 2008

Differential Expression of Keratinocyte-Derived Extracellular Vesicle Mirnas Discriminate Exosomes From Apoptotic Bodies and Microvesicles

scientific article published on 11 September 2018

Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression

scientific article

Effects of oxygen and culture system on in vitro propagation and redifferentiation of osteoarthritic human articular chondrocytes ⬇️

scientific article published on June 4, 2011

Effects of oxygen on zonal marker expression in human articular chondrocytes.

scientific article

Epidermal growth factor modifies the expression and function of extracellular matrix adhesion receptors expressed by peritoneal mesothelial cells from patients on CAPD.

scientific article published in May 1999

Expression of defensin antimicrobial peptides in the peritoneal cavity of patients on peritoneal dialysis.

scientific article

Functional and mechanistic investigation of Shikonin in scarring

scientific article published on 12 January 2015

Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture.

scientific article published in January 2009

HB-EGF is produced in the peritoneal cavity and enhances mesothelial cell adhesion and migration.

scientific article

Human pilot studies reveal the potential of a vitronectin: growth factor complex as a treatment for chronic wounds

In vitro bioactivity of MOEP grafted ePTFE membranes for craniofacial applications

scientific article

Insulin-like growth factor-II bound to vitronectin enhances MCF-7 breast cancer cell migration

scientific article published on 01 June 2003

Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

scientific article published on April 1993

Investigating the potential of Oxymatrine as a psoriasis therapy

scientific article

Mechanistic investigations into interactions between IGF-I and IGFBPs and their impact on facilitating cell migration on vitronectin.

scientific article published on October 2010

Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair

scientific article published on 23 July 2018

Microfibril-associated glycoprotein-2 specifically interacts with a range of bovine and human cell types via alphaVbeta3 integrin

scientific article published on May 1999

Molecular cloning using immune sera of a 22-kDal minor outer membrane protein of Vibrio cholerae

scientific article published on 01 January 1985

Multiple types of data are required to identify the mechanisms influencing the spatial expansion of melanoma cell colonies

scientific article

Potential adhesion mechanisms for localisation of haemopoietic progenitors to bone marrow stroma

scientific article published on February 1994

Potential pitfalls of radiolabel adsorption to ceramic biomaterials.

scientific article published on March 2005

Purification of the 25-kDa Vibrio cholerae major outer-membrane protein and the molecular cloning of its gene: ompV.

scientific article

Quantifying the roles of cell motility and cell proliferation in a circular barrier assay.

scientific article published on 20 February 2013

Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen

scientific article published in June 1992

Responses of keratinocytes to substrate-bound vitronectin: growth factor complexes.

scientific article

Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts

scientific article

Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells.

scientific article published on November 1994

Spatial analysis of biomineralization associated gene expression from the mantle organ of the pearl oyster Pinctada maxima.

scientific article

Specificity and functional effects of antibodies to human stem cell factor.

scientific article

Substrate-bound insulin-like growth factor (IGF)-I-IGF binding protein-vitronectin-stimulated breast cell migration is enhanced by coactivation of the phosphatidylinositide 3-Kinase/AKT pathway by alphav-integrins and the IGF-I receptor.

scientific article published on 13 December 2007

Surface modification by complexes of vitronectin and growth factors for serum-free culture of human osteoblasts

scientific article published on November 2005

The effect of amphiphilic siloxane oligomers on fibroblast and keratinocyte proliferation and apoptosis

scientific article published on November 2010

Timing of pulsed electromagnetic field stimulation does not affect the promotion of bone cell development

scientific article published on December 2005

Traveling wave model to interpret a wound-healing cell migration assay for human peritoneal mesothelial cells.

scientific article published in March 2004

Vitronectin modulates human mesenchymal stem cell response to insulin-like growth factor-I and transforming growth factor beta 1 in a serum-free environment

scientific article published on 01 June 2009

Vitronectin--master controller or micromanager?

scientific article published on 13 September 2013

Vitronectin: Growth Factor Complexes Hold Potential as a Wound Therapy Approach

scientific article published on 17 January 2008

Wound Healing and the Use of Medicinal Plants

scientific article published on 22 September 2019

Xanthine Oxidoreductase: A Novel Therapeutic Target for the Treatment of Chronic Wounds?

scientific article published in March 2018

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