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List of works by Robert J. Freishtat

A Heterotopic Xenograft Model of Human Airways for Investigating Fibrosis in Asthma

scientific article

A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury

scientific article

A cross-sectional ED survey of infantile subclinical methemoglobinemia.

scientific article published on July 2005

Adipocyte exosomes induce transforming growth factor beta pathway dysregulation in hepatocytes: a novel paradigm for obesity-related liver disease

scientific article published on 7 July 2014

Adipocyte-derived exosomal miRNAs: a novel mechanism for obesity-related disease

scientific article

Admission predictor modeling in pediatric interhospital transport

scientific article published on July 2004

Airway Secretory microRNAome Changes during Rhinovirus Infection in Early Childhood

scientific article

Airway platelet activation is associated with airway eosinophilic inflammation in asthma

scientific article published in December 2010

Alterations in insulin-signaling and coagulation pathways in platelets during hyperglycemia-hyperinsulinemia in healthy non-diabetic subject.

scientific article

Antibiotic multidrug resistance in the cystic fibrosis airway microbiome is associated with decreased diversity

scientific article published on 17 September 2018

Association of type 2 cytokines in severe rhinovirus bronchiolitis during infancy with risk of developing asthma: A multicenter prospective study

scientific article published on 01 February 2019

Asthmatic airway epithelium is intrinsically inflammatory and mitotically dyssynchronous

scientific article

Benchmark Evaluation of True Single Molecular Sequencing to Determine Cystic Fibrosis Airway Microbiome Diversity.

scientific article published on 25 May 2018

Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis

scientific article published on 22 February 2019

Cigarette smoke alters tissue inhibitor of metalloproteinase 1 and matrix metalloproteinase 9 levels in the basolateral secretions of human asthmatic bronchial epithelium in vitro

scientific article published in June 2010

Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass

scientific article published on 24 November 2016

Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia

scientific article published on 24 January 2020

Combining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids.

scientific article published on 31 May 2016

Conditional reprogramming of pediatric airway epithelial cells: a new human model to investigate early life respiratory disorders.

scientific article published on 5 October 2017

Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis

scientific article

Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock

scientific article

Developing a clinically feasible personalized medicine approach to pediatric septic shock

scientific article

Differential expression of the Nrf2-linked genes in pediatric septic shock.

scientific article

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock

scientific article

Dual Transcriptomic Profiling of Host and Microbiota during Health and Disease in Pediatric Asthma

scientific article published on 30 June 2015

Dysregulation of PLDN (pallidin) is a mechanism for platelet dense granule deficiency in RUNX1 haplodeficiency

scientific article

Endotype Transitions During the Acute Phase of Pediatric Septic Shock Reflect Changing Risk and Treatment Response.

scientific article published on 15 December 2017

Episodic stridor with latex nipple use in a 2-month-old infant

scientific article published in April 2002

Extracellular cyclophilin levels associate with parameters of asthma in phenotypic clusters

scientific article

Genetic Influences on Vitamin D Status and Forearm Fracture Risk in African American Children ⬇️

scientific article published on August 1, 2012

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.

scientific article

Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock

scientific article published on 7 February 2017

Harmonized outcome measures for use in asthma patient registries and clinical practice

scientific article published on 09 March 2019

Hemolytic and thrombocytopathic characteristics of extracorporeal membrane oxygenation systems at simulated flow rate for neonates* ⬇️

scientific article published on July 1, 2012

High on Aspirin Platelet Reactivity in Pediatric Patients Undergoing the Fontan Procedure

scientific article published on October 2016

High prevalence of vitamin D deficiency among inner-city African American youth with asthma in Washington, DC

scientific article published on 16 March 2010

Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock.

scientific article published in February 2018

Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock

scientific article published on 15 October 2018

Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray.

scientific article

Identification of pediatric septic shock subclasses based on genome-wide expression profiling

scientific article

Imaging, clearance, and controversies in pediatric cervical spine trauma.

scientific article

Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP.

scientific article published on 21 March 2017

In infants with severe bronchiolitis: dual-transcriptomic profiling of nasopharyngeal microbiome and host response

scientific article published on 06 January 2020

Integrating microbial and host transcriptomics to characterize asthma-associated microbial communities

scientific article published on 16 August 2015

Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children

scientific article published on 29 October 2012

Lack of a relation between serum 25-hydroxyvitamin D concentrations and asthma in adolescents

scientific article published on 17 April 2013

Leukocyte subset-derived genomewide expression profiles in pediatric septic shock

scientific article

Machine Learning-Based Prediction of Clinical Outcomes for Children During Emergency Department Triage

scientific article published on 04 January 2019

Microbial diversity within the airway microbiome in chronic pediatric lung diseases

scientific article

Mitotic asynchrony induces transforming growth factor-β1 secretion from airway epithelium

scientific article

NKG2A and CD56 are coexpressed on activated TH2 but not TH1 lymphocytes

scientific article published on December 2005

NKG2A inhibits TH2 cell effector function in vitro

scientific article

Nasopharyngeal Microbiome Diversity Changes over Time in Children with Asthma

scientific article

Natural progression of childhood asthma symptoms and strong influence of sex and puberty.

scientific article

Overcoming heterogeneity in pediatric asthma: tobacco smoke and asthma characteristics within phenotypic clusters in an African American cohort

scientific article published in September 2010

Overweight children: are they at increased risk for severe injury in motor vehicle collisions?

scientific article published on 13 June 2009

P-glycoprotein transporter expression on a549 respiratory epithelial cells is positively correlated with intracellular dexamethasone levels.

scientific article published on December 2010

Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype

scientific article

Pediatric asthma comprises different phenotypic clusters with unique nasal microbiotas

scientific article published on 04 October 2018

Pharmacologically-induced mitotic synchrony in airway epithelial cells as a mechanism of action of anti-inflammatory drugs

scientific article

Platelet-derived microparticles generated by neonatal extracorporeal membrane oxygenation systems.

scientific article

Platelets and platelet extracellular vesicles in hemostasis and sepsis

scientific article published on 15 December 2019

Platelets induce apoptosis during sepsis in a contact-dependent manner that is inhibited by GPIIb/IIIa blockade

scientific article

Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis.

scientific article published on February 2014

Prevalence of vitamin D insufficiency in African American children with forearm fractures: a preliminary study

scientific article

Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology.

scientific article

Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.

scientific article published on 06 April 2017

RSV vs. rhinovirus bronchiolitis: difference in nasal airway microRNA profiles and NFκB signaling.

scientific article published on 15 December 2017

Rhinovirus infection in young children is associated with elevated airway TSLP levels.

scientific article

Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity.

scientific article published on 08 January 2009

Serum cathelicidin, nasopharyngeal microbiota, and disease severity among infants hospitalized with bronchiolitis.

scientific article

Sex differences in the association between neck circumference and asthma

scientific article

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017. An Official American Thoracic Society Workshop Report

scientific article published on 01 October 2019

Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model.

scientific article published on 29 January 2014

The Global Emergence of Unregulated Stem Cell Treatments for Respiratory Diseases. Professional Societies Need to Act.

scientific article published in August 2016

The relationship between nasopharyngeal CCL5 and microbiota on disease severity among infants with bronchiolitis.

scientific article published on 17 March 2017

The temporal dynamics of the tracheal microbiome in tracheostomised patients with and without lower respiratory infections.

scientific article published on 10 August 2017

The temporal version of the pediatric sepsis biomarker risk model

scientific article

Toward early identification of acute lung injury in the emergency department ⬇️

scientific article

Tracheal Microbiota in Patients With a Tracheostomy Before, During and After an Acute Respiratory Infection

scientific article published on 01 November 2018

Two sampling methods yield distinct microbial signatures in the nasopharynges of asthmatic children

scientific article

Understanding genomics: implications for the emergency medicine physician and the treatment of asthma.

scientific article

Unproven Stem Cell Treatments for Lung Disease—An Emerging Public Health Problem

article

VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice

scientific article

Validating the genomic signature of pediatric septic shock.

scientific article

Validation of a gene expression-based subclassification strategy for pediatric septic shock.

scientific article

Vitamin d in pediatric inpatients with respiratory illnesses

scientific article published on October 2013

miRTarVis+: Web-based interactive visual analytics tool for microRNA target predictions.

scientific article published on 06 June 2017

miRTarVis: an interactive visual analysis tool for microRNA-mRNA expression profile data

article

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