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List of works by Maria Masucci

14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases

scientific article published on 11 November 2019

A bacterial cytotoxin identifies the RhoA exchange factor Net1 as a key effector in the response to DNA damage

scientific article

A bacterial genotoxin causes virus reactivation and genomic instability in Epstein-Barr virus infected epithelial cells pointing to a role of co-infection in viral oncogenesis

scientific article published on 29 October 2018

A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases

scientific article published on 28 February 2010

A minimal glycine-alanine repeat prevents the interaction of ubiquitinated I kappaB alpha with the proteasome: a new mechanism for selective inhibition of proteolysis

scientific article published on August 1998

A novel mechanism for regulation of the type I IFN response by herpesvirus deconjugases.

scientific article published on 11 April 2018

A partially agonistic peptide acts as a selective inducer of apoptosis in CD8+ CTLs.

scientific article published on September 1999

A single specific amino acid residue in peptide antigens is sufficient to activate memory CTL: potential role of cross-reactive peptides in memory T cell maintenance.

scientific article published on January 1999

A transgenic mouse model of the ubiquitin/proteasome system

scientific article published on 20 July 2003

Aberrant expression of HLA class-I antigens in Burkitt lymphoma cells

scientific article published on February 1991

Activation of B lymphocytes by Epstein-Barr virus/CR2 receptor interaction

scientific article

Activation of cytotoxic activity of human blood lymphocytes by tumor-promoting compounds

scientific article published on 01 May 1984

Activation of epitope-specific memory cytotoxic T lymphocyte responses by synthetic peptides.

scientific article published on August 1996

Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines.

scientific article

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

scholarly article

Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.

scientific article published in October 2002

Allele-specific down-regulation of MHC class I antigens in Burkitt lymphoma lines.

scientific article published in May 1989

Allo-restricted cytotoxicity recognizing EBV-determined antigens. Comments

scientific article

An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19.

scientific article published on 13 March 2013

Antigen processing and presentation by EBV-carrying cell lines: cell-phenotype dependence and influence of the EBV-encoded LMP1.

scientific article published on March 1993

B cell activation by the nontransforming P3HR-1 substrain of the Epstein-Barr virus (EBV).

scientific article published in July 1986

B cell phenotype-dependent expression of the Epstein-Barr virus nuclear antigens EBNA-2 to EBNA-6: studies with somatic cell hybrids

scientific article published on December 1991

Bacterial genotoxin triggers FEN1-dependent RhoA activation, cytoskeleton remodeling and cell survival.

scientific article

CD40 cross-linking enhances the immunogenicity of Burkitt's-lymphoma cell lines

scientific article published on 10 December 1999

Capacity of Epstein-Barr virus to infect monocytes and inhibit their development into dendritic cells is affected by the cell type supporting virus replication

scientific article published in October 2004

Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells

scientific article

Cell phenotype dependent down-regulation of MHC class I antigens in Burkitt's lymphoma cells

scientific article published on 01 January 1990

Cell phenotype dependent expression of MHC class I antigens in Burkitt's lymphoma cell lines

scientific article published on February 1, 1991

Cell-mediated immunity against Epstein-Barr virus infected B lymphocytes

scientific article published on January 1982

Characterization of EBV-carrying B-cell populations in healthy seropositive individuals with regard to density, release of transforming virus and spontaneous outgrowth

scientific article

Characterization of an human leucocyte antigen A2-restricted Epstein-Barr virus nuclear antigen-1-derived cytotoxic T-lymphocyte epitope.

scientific article

Chronic exposure to the cytolethal distending toxins of Gram-negative bacteria promotes genomic instability and altered DNA damage response.

scientific article

Combined treatment with interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha up-regulates the expression of HLA class I determinants in Burkitt lymphoma lines.

scientific article published in December 1988

Correction: The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization

scientific article published on 01 February 2020

Cytotoxic factor produced by human blood lymphocytes of low density upon exposure to autologous B cells.

scientific article published in March 1986

Defective cell-mediated response to EBV-transformed B cells in a healthy individual with regular EBV antibody titers

scientific article published in August 1987

Different programs of activation-induced cell death are triggered in mature activated CTL by immunogenic and partially agonistic peptide ligands

scientific article

Differential effect of cyclosporin-A on the mixed-lymphocyte culture-induced proliferative and cytotoxic responses of T lymphocytes with different cell densities

article

Differential expression of HLA antigens on human B-cell lines of normal and malignant origin: a consequence of immune surveillance or a phenotypic vestige of the progenitor cells?

scientific article

Differential recognition of tumor-derived and in vitro Epstein-Barr virus-transformed B-cell lines by fetal calf serum-specific T4-positive cytotoxic T-lymphocyte clones.

scientific article

Differential regulation of MHC class-I-restricted and unrestricted cytotoxicity by the Us3 protein kinase of herpes simplex virus-1.

scientific article published in December 2004

Down-regulation of the EBV-encoded membrane protein (LMP) in burkitt lymphomas

scientific article published on 01 September 1987

EBV and genomic instability--a new look at the role of the virus in the pathogenesis of Burkitt's lymphoma.

scientific article published on 18 July 2009

Effect of anchor residue modifications on the stability of HLA-A11/peptide complexes

scientific article published on January 1995

Effect of combined T- and B-cell depletion of allogeneic HLA-mismatched bone marrow graft on the magnitude and kinetics of Epstein-Barr virus load in the peripheral blood of bone marrow transplant recipients

scientific article published in October 2004

Effect of cyclosporin-A (CsA) on the ability of T lymphocyte subsets to inhibit the proliferation of autologous EBV-transformed B cells

scientific article published in March 1985

Effect of different Epstein-Barr virus-determined antigens (EBNA, EA, and VCA) on the leukocyte migration of healthy donors and patients with infectious mononucleosis and certain immunodeficiencies

scientific article published in January 1982

Effect of interferon-alpha 1 from E. coli on some cell functions.

scientific article

Effect of interleukin-7 on the in vitro development and maturation of monocyte derived human dendritic cells.

scientific article

Emerging topics in human tumor virology

scientific article published on 23 April 2014

Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

scientific article published on 15 August 2005

Epitope-dependent selection of highly restricted or diverse T cell receptor repertoires in response to persistent infection by Epstein-Barr virus

scientific article published on July 1997

Epstein-Barr virus (EBV) load in bone marrow transplant recipients at risk to develop posttransplant lymphoproliferative disease: prophylactic infusion of EBV-specific cytotoxic T cells.

scientific article published in February 2000

Epstein-Barr virus (EBV)-encoded membrane protein LMP1 from a nasopharyngeal carcinoma is non-immunogenic in a murine model system, in contrast to a B cell-derived homologue.

scientific article published on January 1994

Epstein-Barr virus encoded microRNAs target SUMO-regulated cellular functions

scientific article published on 30 September 2014

Epstein-Barr virus inhibits the development of dendritic cells by promoting apoptosis of their monocyte precursors in the presence of granulocyte macrophage-colony-stimulating factor and interleukin-4.

scientific article published in May 2002

Epstein-Barr virus oncogenesis and the ubiquitin-proteasome system.

scientific article published on March 2004

Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma

scientific article published on 26 February 2007

Epstein-Barr virus: adaptation to a life within the immune system

scientific article published on April 1994

Epstein-barr virus encodes three bona fide ubiquitin-specific proteases

scientific article

Experimental and clinical data for the role of NK-cells in immunosurveillance

scientific article published on May 1, 1984

Expression of the Epstein-Barr virus (EBV)-encoded membrane antigen (LMP) increases the stimulatory capacity of EBV-negative B lymphoma lines in allogeneic mixed lymphocyte cultures

scientific article published on October 1990

Expression of the Epstein-Barr virus (EBV)-encoded membrane protein LMP1 impairs the in vitro growth, clonability and tumorigenicity of an EBV-negative Burkitt lymphoma line

scientific article published on July 1992

Expression of the Epstein-Barr virus encoded EBNA-1 gene in stably transfected human and murine cell lines

scientific article published in October 1988

Functional inactivation of EBV-specific T-lymphocytes in nasopharyngeal carcinoma: implications for tumor immunotherapy

scientific article

Functional p53 chimeras containing the Epstein-Barr virus Gly-Ala repeat are protected from Mdm2- and HPV-E6-induced proteolysis

scientific article

GFP reporter mouse models of UPS proteolytic function

scientific article published in May 2006

Generation of T cell clones binding F(ab')2 fragments of the idiotypic immunoglobulin in patients with monoclonal gammopathy

scientific article published on January 1991

Generation of lymphoblastoid cell lines (LCLs).

scientific article published on January 2001

Generation of polyclonal EBV-specific CTL cultures and clones

article

HLA-A11 epitope loss isolates of Epstein-Barr virus from a highly A11+ population

scientific article published on April 1993

Helicobacter pylori affects the cellular deubiquitinase USP7 and ubiquitin-regulated components TRAF6 and the tumour suppressor p53

scientific article published on 04 December 2010

Help signals provided by lymphokines modulate the activation and apoptotic programs induced by partially agonistic peptides in specific cytotoxic T lymphocytes

scientific article published in October 2005

Hepatitis C virus core protein induces an anergic state characterized by decreased interleukin-2 production and perturbation of mitogen-activated protein kinase responses

scientific article published on February 2005

Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1.

scientific article published on 3 April 2012

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.

scientific article published on 22 January 2018

High avidity binding to DNA protects ubiquitylated substrates from proteasomal degradation.

scientific article published on 6 April 2011

High structural side chain specificity required at the second position of immunogenic peptides to obtain stable MHC/peptide complexes

scientific article

High-resolution one-dimensional isoelectric focusing of mouse MHC class I antigens

scientific article published on 01 January 1990

Human T Cell Growth Factor (TCGF) produced by repeated stimulation of non-adherent human lymphocytes

scientific article published on 01 January 1982

Immune escape by Epstein-Barr virus (EBV) carrying Burkitt's lymphoma: in vitro reconstitution of sensitivity to EBV-specific cytotoxic T cells

scientific article published on November 1992

Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

scientific article

Inhibition of serine-peptidase activity enhances the generation of a survivin-derived HLA-A2-presented CTL epitope in colon-carcinoma cells.

scientific article

Inhibition of ubiquitin-dependent proteolysis by a synthetic glycine-alanine repeat peptide that mimics an inhibitory viral sequence

scientific article published in July 2002

Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat

scientific article

Integration of a short Epstein-Barr virus DNA fragment in a B95-8 virus converted Burkitt lymphoma line expressing Epstein-Barr nuclear antigens EBNA2 and EBNA5.

scientific article published on July 1993

Interaction of gamma-herpesvirus genome maintenance proteins with cellular chromatin.

scientific article

Interleukin-10 abrogates the inhibition of Epstein-Barr virus-induced B-cell transformation by memory T-cell responses.

scientific article published in December 1998

Is the activity of partially agonistic MHC:peptide ligands dependent on the quality of immunological help?

scientific article published on December 2006

Limiting dilution assay

scientific article published on 01 January 2001

Lysis of tumor biopsy cells by autologous T lymphocytes activated in mixed cultures and propagated with T cell growth factor.

scientific article

Lysis of tumor biopsy cells by blood lymphocyte subsets of various densities. Autologous and allogeneic studies

scientific article published on 01 February 1984

MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells

scientific article

Manipulation of immune responses by Epstein-Barr virus.

scientific article

Mechanisms of allele-selective down-regulation of HLA class I in Burkitt's lymphoma

scientific article

Methylation of discrete sites within the enhancer region regulates the activity of the Epstein-Barr virus BamHI W promoter in Burkitt lymphoma lines ⬇️

scientific article published on January 1, 1992

Mitotic infidelity and centrosome duplication errors in cells overexpressing tripeptidyl-peptidase II.

scientific article published on February 2005

Modulation of human blood lymphocyte cytotoxicity by the phorbol ester tumor promoter P(Bu)2: Increase of target binding, impairment of effector recycling, and activation of lytic potential which is independent of IL-2

scientific article published on 01 March 1985

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

scientific article published on 29 April 2002

Natural killer cell sensitivity of human lymphoid lines of B-cell origin does not correlate with tumorigenicity or with the expression of certain differentiation markers.

scientific article

Natural variants of the immunodominant HLA A11-restricted CTL epitope of the EBV nuclear antigen-4 are nonimmunogenic due to intracellular dissociation from MHC class I:peptide complexes ⬇️

scientific article published on December 1, 1997

Non-infectious fluorimetric assay for phenotyping of drug-resistant HIV proteinase mutants

scientific article published on 9 March 2006

Over-expression of C-myc increases the sensitivity of Epstein-Barr virus immortalized lymphoblastoid cells to non-MHC-restricted cytotoxicity

scientific article published in April 1993

Oxidative stress enables Epstein-Barr virus-induced B-cell transformation by posttranscriptional regulation of viral and cellular growth-promoting factors

scientific article

Paired Epstein-Barr virus (EBV)-negative and EBV-converted Burkitt lymphoma lines: stimulatory capacity in allogeneic mixed lymphocyte cultures

scientific article

Patterns of Epstein-Barr virus infection in non-neoplastic lymphoid tissue

scientific article

Pharmacological disintegration of lipid rafts decreases specific tetramer binding and disrupts the CD3 complex and CD8 heterodimer in human cytotoxic T lymphocytes

scientific article published in February 2003

Phenotype-dependent differences in proteasome subunit composition and cleavage specificity in B cell lines

scientific article

Proteasome inhibitors reconstitute the presentation of cytotoxic T-cell epitopes in Epstein-Barr virus-associated tumors

scientific article published on October 2002

Random coil conformation of a Gly/Ala-rich insert in IκBα excludes structural stabilization as the mechanism for protection against proteasomal degradation

scientific article published on 01 December 1998

Regression assay

scientific article published on 01 January 2001

Regulation of Telomere Homeostasis during Epstein-Barr virus Infection and Immortalization.

scientific article published on 9 August 2017

Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering.

scholarly article

Regulation of lck degradation and refractory state in CD8+ cytotoxic T lymphocytes

scientific article

Remodeling of the epitope repertoire of a candidate idiotype vaccine by targeting to lysosomal degradation in dendritic cells

article

Reply to ‘Ubiquitin/proteasome system’

scientific article published on 01 August 2000

Reversion of tumorigenicity and decreased agarose clonability after EBV conversion of an igh/myc translocation-carrying be line

scientific article published on 01 February 1989

Role of T cell subpopulations in the control of the proliferative potential of EBV transformed B cells.

scientific article published in May 1983

Search for the critical characteristics of phenotypically different B cell lines, Burkitt lymphoma cells and lymphoblastoid cell lines, which determine differences in their functional interaction with allogeneic lymphocytes

scientific article published on January 1991

Selective induction of allostimulatory capacity after 5-azaC treatment of EBV carrying but not EBV negative Burkitt lymphoma cell lines

scientific article published on April 1993

Selective inhibitory effect of Hu-IFN-gamma on the agarose clonability of tumor-derived lymphoid cell lines.

scientific article published in January 1985

Single administration of low dose cyclophosphamide augments the antitumor effect of dendritic cell vaccine

scientific article published on 18 April 2007

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

scientific article published on 21 November 2004

Soluble factors released by virus specific activated cytotoxic T-lymphocytes induce apoptotic death of astroglioma cell lines

scientific article published in April 2003

Solvent exposed side chains of peptides bound to HLA A*1101 have similar effects on the reactivity of alloantibodies and specific TCR.

scientific article published on June 1996

Stabilization of proteasomal substrates by viral repeats

scientific article

Stabilization signals: a novel regulatory mechanism in the ubiquitin/proteasome system

scientific article

Stimulation with allogeneic Epstein-Barr virus-transformed lymphoblastoid cell lines generates HLA class I-specific CTLs with different target cell avidity.

scientific article published in October 1991

Supermotif peptide binding and degeneracy of MHC: peptide recognition in an EBV peptide-specific CTL response with highly restricted TCR usage

scientific article

Suppression of basal, PMA- and IFN-alpha-, but not IFN-gamma-induced expression of HLA class I in v-myc-transformed U-937 monoblasts

scientific article published on November 1992

T cell recognition of Epstein-Barr virus associated lymphomas

scientific article published on January 1, 1992

T-cell-mediated inhibition of EBV-induced B-cell transformation: recognition of virus particles

scientific article

TPPII promotes genetic instability by allowing the escape from apoptosis of cells with activated mitotic checkpoints.

scientific article

Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus.

scientific article

Tetramer binding and secretion of interferon-gamma in response to antigenic stimulation are compatible with a range of affinities of MHC:TCR interaction and distinct programs of cytotoxic T-lymphocyte activation

scientific article published on October 2002

The Epstein-Barr virus latent membrane protein-1 (LMP1) induces interleukin-10 production in Burkitt lymphoma lines

scientific article published on April 1994

The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus

scientific article

The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species.

scholarly article

The Epstein-Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins

scientific article published on 28 January 2013

The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization

scientific article published on 11 September 2019

The Epstein–Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress ⬇️

scientific article published on March 11, 2011

The Haemophilus ducreyi cytolethal distending toxin activates sensors of DNA damage and repair complexes in proliferating and non-proliferating cells

scientific article published on February 2002

The MAPK signaling cascade is a central hub in the regulation of cell cycle, apoptosis and cytoskeleton remodeling by tripeptidyl-peptidase II.

scientific article published on 24 November 2008

The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation

scientific article

The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bcl-2 family member Bad.

scientific article published in November 2003

The clonal composition of a peptide-specific oligoclonal CTL repertoire selected in response to persistent EBV infection is stable over time.

scientific article published on July 1998

The epstein-Barr-virus-encoded membrane protein LMP but not the nuclear antigen EBNA-1 induces rejection of transfected murine mammary carcinoma cells

scientific article published on July 1991

The hepatitis C virus core protein modulates T cell responses by inducing spontaneous and altering T-cell receptor-triggered Ca2+ oscillations

scientific article published on 13 March 2003

The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B.

scientific article published in December 2003

The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4

scientific article published on March 1996

The role of methylation in the phenotype-dependent modulation of Epstein-Barr nuclear antigen 2 and latent membrane protein genes in cells latently infected with Epstein-Barr virus

scientific article published on November 1989

The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation

scientific article

The tumor promoter phorbol-12,13-dibutyrate [P(Bu)2] stimulates cytotoxic activity of human blood lymphocytes.

scientific article

The ubiquitin C-terminal hydrolase UCH-L1 promotes bacterial invasion by altering the dynamics of the actin cytoskeleton

scientific article published on November 2010

The ubiquitin C-terminal hydrolase UCH-L1 regulates B-cell proliferation and integrin activation

scientific article published on August 2009

The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway

scientific article

The ubiquitin specific protease-4 (USP4) interacts with the S9/Rpn6 subunit of the proteasome

scientific article published on 26 September 2012

The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins

scientific article published on March 2006

The ubiquitin/proteasome system in Epstein-Barr virus latency and associated malignancies.

scientific article

Thioredoxin 80-activated-monocytes (TAMs) inhibit the replication of intracellular pathogens

scientific article

Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints

scientific article

Transcription profiling of Epstein-Barr virus nuclear antigen (EBNA)-1 expressing cells suggests targeting of chromatin remodeling complexes

scientific article

Transformation-associated Epstein-Barr virus antigens as targets for immune attack

scientific article

Tumor viruses and replicative immortality--avoiding the telomere hurdle.

scientific article published on 28 January 2014

Ubiquitin C-terminal hydrolase-L1 interacts with adhesion complexes and promotes cell migration, survival, and anchorage independent growth.

scientific article published on 29 August 2012

Use of cryopreserved lymphocytes for the indirect leukocyte migration inhibition assay

scientific article published on 01 January 1981

Variations in proteasome subunit composition and enzymatic activity in B-lymphoma lines and normal B cells

scientific article published in 2000

Viral immunopathology of human tumors

scientific article published on October 1993

c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells.

scientific article

cis-Inhibition of proteasomal degradation by viral repeats: impact of length and amino acid composition

scientific article published in June 2001

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