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List of works by Yvonne Genzel

A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor.

scientific article published on 16 July 2010

Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detection.

scientific article published on December 2004

CAP, a new human suspension cell line for influenza virus production.

scientific article

Capture of cell culture-derived influenza virus by lectins: strain independent, but host cell dependent.

scientific article published on November 2008

Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system

scientific article published on 14 September 2021

Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media.

scientific article

Characterization of flow conditions in 2 L and 20 L wave bioreactors® using computational fluid dynamics

scientific article published on 01 January 2010

Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line

scientific article published on 8 October 2013

Comparison of metabolic flux distributions for MDCK cell growth in glutamine- and pyruvate-containing media.

scientific article published on 24 January 2008

Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles

scientific article

Designing cell lines for viral vaccine production: Where do we stand?

scientific article published on 22 April 2015

Differential activation of host cell signalling pathways through infection with two variants of influenza A/Puerto Rico/8/34 (H1N1) in MDCK cells

scientific article published on 5 August 2010

Effect of influenza virus infection on key metabolic enzyme activities in MDCK cells.

scientific article

Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution

scientific article published on 01 January 2004

Establishment of a mink enteritis vaccine production process in stirred-tank reactor and Wave Bioreactor microcarrier culture in 1-10 L scale

scientific article published on 12 March 2007

Evaluating differences of metabolic performances: statistical methods and their application to animal cell cultivations.

scientific article published on 30 April 2013

Experimental characterization of flow conditions in 2- and 20-l bioreactors with wave-induced motion

scientific article published on 04 March 2011

Expression, purification, and characterization of a His6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cells.

scientific article published on 8 October 2010

Glycan analysis in cell culture-based influenza vaccine production: influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin.

scientific article published on 14 May 2009

Growth behavior of number distributed adherent MDCK cells for optimization in microcarrier cultures.

scientific article

Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccines.

scientific article published on May 2007

Herstellung moderner Grippeimpfstoffe

High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells

scientific article published on 25 February 2014

High-density microcarrier cell cultures for influenza virus production.

scientific article published on 7 January 2011

High-performance anion-exchange chromatography using on-line electrolytic eluent generation for the determination of more than 25 intermediates from energy metabolism of mammalian cells in culture

scientific article published on 23 June 2006

Impact of cultivation conditions on N-glycosylation of influenza virus a hemagglutinin produced in MDCK cell culture.

scientific article

Impact of different influenza cultivation conditions on HA N-Glycosylation

scientific article

Impact of host cell line adaptation on quasispecies composition and glycosylation of influenza A virus hemagglutinin

scientific article

Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production-Flow cytometry and mathematical modeling

scientific article

Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells

scientific article

MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation.

scientific article published on 9 July 2010

Measurement of key metabolic enzyme activities in mammalian cells using rapid and sensitive microplate-based assays.

scientific article published in October 2010

Metabolic adaptation of MDCK cells to different growth conditions: effects on catalytic activities of central metabolic enzymes.

scientific article published on 15 June 2011

Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling

scientific article

Metabolic flux model for an anchorage-dependent MDCK cell line: characteristic growth phases and minimum substrate consumption flux distribution

scientific article

Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture

scientific article published on June 2004

Microbiological transformations. 47. A step toward a green chemistry preparation of enantiopure (S)-2-, -3-, and -4-pyridyloxirane via an epoxide hydrolase catalyzed kinetic resolution

scientific article

Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension.

scientific article

New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation

scientific article

PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia.

scientific article published on 27 June 2013

Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production

scientific article published on 06 August 2020

Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells

scientific article published on 21 May 2015

Production of high-titer human influenza A virus with adherent and suspension MDCK cells cultured in a single-use hollow fiber bioreactor.

scientific article

Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortants

scientific article published on 12 June 2012

Proteome analysis of virus-host cell interaction: rabies virus replication in Vero cells in two different media

scientific article published on 15 May 2013

Purification and characterization of a highly selective epoxide hydrolase from Nocardia sp. EH1.

scientific article published in April 1998

Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell lines.

scientific article

Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamics

scientific article published on 28 April 2010

Serum-free influenza virus production avoiding washing steps and medium exchange in large-scale microcarrier culture.

scientific article published on 19 January 2006

Simultaneous extraction of several metabolites of energy metabolism and related substances in mammalian cells: optimization using experimental design

scientific article published in November 2007

Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells.

scientific article

The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis

scientific article

The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells.

scientific article published on 18 March 2014

The relation between growth phases, cell volume changes and metabolism of adherent cells during cultivation

scientific article published on 19 February 2013

Vaccine production: upstream processing with adherent or suspension cell lines.

scientific article published on January 2014

Virus-host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: a proteomic approach.

scientific article

Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media.

scientific article

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