List of works - Stephen Daley

A Role for Intrathymic B Cells in the Generation of Natural Regulatory T Cells

scientific article published on 28 May 2014

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

scientific article published on 01 November 2019

A timeline demarcating two waves of clonal deletion and Foxp3 upregulation during thymocyte development.

scientific article published on 29 October 2015

Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells

scientific article

Cell death and thymic tolerance

scientific article

Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning

scientific article published on 25 April 2006

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

scientific article published on 18 September 2019

Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance.

scientific article published on 8 September 2008

Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.

scientific article published on 21 January 2013

IL-2 prevents deletion of developing T-regulatory cells in the thymus.

scientific article published on 31 March 2017

Immune privilege induced by regulatory T cells in transplantation tolerance

scientific article published on October 2006

Indirect presentation in the thymus limits naïve and regulatory T cell differentiation by promoting deletion of self-reactive thymocytes.

scientific article published on 7 February 2018

MHCI and CD8 lineage commitment. Prolonged access to thymic epithelial MHCI seals CD8⁺ lineage commitment

scientific article published on 10 March 2015

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation

scientific article

Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells

scientific article published on 13 January 2014

Ocular antigen does not cause disease unless presented in the context of inflammation.

scientific article published on 27 October 2017

Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation.

scientific article

Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.

scientific article published on 12 December 2013

Regulation of the IL-21 gene by the NF-κB transcription factor c-Rel

scientific article published on 16 July 2010

Regulatory T cells in transplantation

scientific article published on 14 February 2006

The Impact of MHC Class I Dose on Development and Maintenance of the Polyclonal Naive CD8+ T Cell Repertoire

scientific article published on 27 April 2020

The NF- B Transcription Factor c-Rel Is Required for Th17 Effector Cell Development in Experimental Autoimmune Encephalomyelitis

scientific article published on 21 September 2011

Understanding the drivers of MHC restriction of T cell receptors

scientific article published on 01 July 2018

αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors

scientific article published on 03 May 2018

List of works by Stephen Daley

A Role for Intrathymic B Cells in the Generation of Natural Regulatory T Cells

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

A timeline demarcating two waves of clonal deletion and Foxp3 upregulation during thymocyte development.

Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells

Cell death and thymic tolerance

Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance.

Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.

IL-2 prevents deletion of developing T-regulatory cells in the thymus.

Immune privilege induced by regulatory T cells in transplantation tolerance

Indirect presentation in the thymus limits naïve and regulatory T cell differentiation by promoting deletion of self-reactive thymocytes.

MHCI and CD8 lineage commitment. Prolonged access to thymic epithelial MHCI seals CD8⁺ lineage commitment

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation

Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells

Ocular antigen does not cause disease unless presented in the context of inflammation.

Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation.

Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.

Regulation of the IL-21 gene by the NF-κB transcription factor c-Rel

Regulatory T cells in transplantation

The Impact of MHC Class I Dose on Development and Maintenance of the Polyclonal Naive CD8+ T Cell Repertoire

The NF- B Transcription Factor c-Rel Is Required for Th17 Effector Cell Development in Experimental Autoimmune Encephalomyelitis

Understanding the drivers of MHC restriction of T cell receptors

αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors