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List of works by Mathias Müller

A Mammary-Specific Promoter Directs Expression of Growth Hormone not only to the Mammary Gland, but also to Bergman Glia Cells in Transgenic Mice

A Time and Cost-effective Method for κ-casein Allele A and B Genotyping of Breeding Bulls

A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C).

scientific article published on 23 July 2011

A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription

scientific article published on 02 July 2019

A mouse model to identify cooperating signaling pathways in cancer

article

A time- and dose-dependent STAT1 expression system

scientific article

Activated STAT5 confers resistance to intestinal injury by increasing intestinal stem cell proliferation and regeneration

scientific article published on 8 January 2015

An unusual splice defect in the mitofusin 2 gene (MFN2) is associated with degenerative axonopathy in Tyrolean Grey cattle

scientific article (publication date: 2011)

Association of nonsense mutation of dystrophin gene with disruption of sarcoglycan complex in X-linked dilated cardiomyopathy

scientific article published in May 2000

Bacterial polyphosphates interfere with the innate host defense to infection

scientific article published on 12 August 2020

Base substitutions in the sequences flanking microsatellite markers HMS3 and ASB2 interfere with parentage testing in the Lipizzan horse.

scientific article published in February 2001

CD13/aminopeptidase N is a negative regulator of mast cell activation

scientific article

CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response

scientific article

CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance

scientific article published on 08 August 2013

Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses

scientific article published on 26 January 2017

Cardiac specific expression of the green fluorescent protein during early murine embryonic development

scientific article published in December 1998

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

scientific article

Characterization of endogenous retroviruses in sheep

scientific article

Characterization of porcine endogenous retrovirus gamma pro-pol nucleotide sequences

scientific article published on November 2002

Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes

scientific article

Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression

scientific article published on 16 January 2017

Cloned transgenic farm animals produce a bispecific antibody for T cell-mediated tumor cell killing

scientific article

Commentary on H. Ide et al., “Tyk2 expression and its signaling enhances the invasiveness of prostate cancer cells”

scientific article published on 17 December 2007

Comparative human–mouse–rat sequence analysis of the ICAM gene cluster on HSA 19p13.2 and a 185-kb porcine region from SSC 2q

article

Comparative oncology: The paradigmatic example of canine and human mast cell neoplasms

scientific article published on 24 September 2018

Comparing the applicability of CGE-on-the-chip and SDS-PAGE for fast pre-screening of mouse serum samples prior to proteomics analysis

scientific article published in November 2008

Composition of parental mitochondrial DNA in cloned bovine embryos.

scientific article

Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance

scientific article published on October 2012

Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection

scientific article (publication date: 2012)

Conditional ablation of TYK2 in immunity to viral infection and tumor surveillance

scientific article published on 3 April 2014

Contribution of cell culture additives to the two-dimensional protein patterns of mouse macrophages

scientific article published in April 2006

Control of Leishmania major in the absence of Tyk2 kinase.

scientific article

Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling

scientific article published on 31 January 2011

Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex

scientific article

Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis ⬇️

scientific article published on 2 May 2011

Deciphering host genotype-specific impacts on the metabolic fingerprint of Listeria monocytogenes by FTIR spectroscopy

scientific article

Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.

scientific article published on 20 July 2009

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

scientific article published on 21 August 2018

Development of a transgenic mouse model susceptible to human coronavirus 229E.

scientific article

Different roles for B-carotene and vitamin A in the reproduction on rabbits

Disease resistance in farm animals

scientific article published on September 1991

Effect of insulin-like growth factor I (IGF-I) at high concentrations on blastocyst development of bovine embryos produced in vitro

article

Effect of morphological properties of transferred embryonic stages on tubal migration Implications for in vivo culture in the bovine oviduct.

scientific article published on 30 December 2004

Effects of serum starvation and re-cloning on the efficiency of nuclear transfer using bovine fetal fibroblasts.

scientific article published in March 1999

Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models.

scientific article

Endoscopic embryo collection and embryo transfer into the oviduct and the uterus of pigs

scientific article published in April 1997

Fixed nucleotide differences on the Y chromosome indicate clear divergence between Equus przewalskii and Equus caballus

scientific article (publication date: December 2003)

Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression

scientific article

Generation of mice with a conditional Stat1 null allele

article published in 2011

Genetic variation in functionally important domains of the bovine mtDNA control region

scientific article

Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.

scientific article published on February 2015

Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression

scientific article published on 30 October 2018

High activation of STAT5A drives peripheral T-cell lymphoma and leukemia

scientific article published on 31 January 2020

High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells

scientific article published on 16 November 2015

Homeostatic and Interferon-induced gene expression represent different states of promoter-associated transcription factor ISGF3

article

Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis

scientific article

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

scientific article

Human nerve growth factor beta (hNGF-β): mammary gland specific expression and production in transgenic rabbits

article

IDO1+ Paneth cells promote immune escape of colorectal cancer

scientific article published on 22 May 2020

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

scientific article

IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent Mechanism

scientific article published on 01 December 2004

IFNs and STATs in innate immunity to microorganisms

Identification of an indispensable role for tyrosine kinase 2 in CTL-mediated tumor surveillance

scientific article

Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer

article

Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation

scientific article

In Vivo Target Validation: Methodology and Case Studies on the Janus Kinase Tyk2

In vivo footprinting of the IRF-1 promoter: inducible occupation of a GAS element next to a persistent structural alteration of the DNA.

scientific article published on August 1994

In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis

scientific article

In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity

scientific article

Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo

scientific article

Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells

scientific article published on 2 March 2011

Interferon response pathways--a paradigm for cytokine signalling?

scientific article published on January 1994

Interferons limit inflammatory responses by induction of tristetraprolin

scientific article published on 02 March 2006

Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.

scientific article

Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis

scientific article

Intestinal Microbiota Signatures Associated with Inflammation History in Mice Experiencing Recurring Colitis

scientific article

Intracellular, genetic or congenital immunisation--transgenic approaches to increase disease resistance of farm animals

scientific article published on January 1996

Intrafallopian transfer of gametes and early stage embryos for in vivo culture in cattle

scientific article published on 30 December 2004

Isolation of Y chromosome-specific microsatellites in the horse and cross-species amplification in the genus Equus.

scientific article published in March 2004

JAKs and STATs branch out.

scientific article published in September 1996

Jak-Stat Signaling : From Basics to Disease

article

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

scientific article

Lactotransferrin-Cre reporter mice trace neutrophils, monocytes/macrophages and distinct subtypes of dendritic cells

scientific article published on 21 February 2014

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes

scientific article published on July 2013

Listeria monocytogenes infection rewires host metabolism with regulatory input from type I interferons

scientific article published on 08 July 2021

Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery

scientific article published on 09 January 2014

Loss of STAT3 in murine NK cells enhances NK cell-dependent tumor surveillance

scientific article published on 02 September 2014

Lymphangiogenesis in a mouse model of renal transplant rejection extends life span of the recipients

scientific article published on 03 September 2019

Mammary gland development is delayed in mice deficient for aminopeptidase N.

scientific article

Microbial communities in dairy processing environment floor-drains are dominated by product-associated bacteria and yeasts

article by Kerstin Schön et al published December 2016 in Food Control

Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning

Mitochondrial DNA heteroplasmy in ovine fetuses and sheep cloned by somatic cell nuclear transfer

scientific article

Molecular characterization of the porcine TYK2 gene on SSC 2q1.3-->q2.1.

scientific article

Molecular cloning of porcine Mx cDNAs: new members of a family of interferon-inducible proteins with homology to GTP-binding proteins

scientific article published on April 1, 1992

Multifaceted Antiviral Actions of Interferon-stimulated Gene Products

article

Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1

scientific article published on 01 February 2019

Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice

scientific article published on 22 January 2015

NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity

scientific article published on 04 February 2019

Non-balanced mix of mitochondrial DNA in cloned cattle produced by cytoplast-blastomere fusion.

scientific article published in April 1998

Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons

scientific article published on 27 April 2015

Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression

scientific article published on July 2010

Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus

scientific article published in September 2005

Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity

scientific article published on 19 May 2016

Nucleolar protein allocation and ultrastructure in bovine embryos produced by nuclear transfer from embryonic cells

scientific article

Nucleolar proteins and ultrastructure in bovine in vivo developed, in vitro produced, and parthenogenetic cleavage-stage embryos

scientific article

Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

scientific article published on 25 October 2018

Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses

scientific article

Organ-specific and differential requirement of TYK2 and IFNAR1 for LPS-induced iNOS expression in vivo

scientific article

PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes

scientific article

Partial impairment of cytokine responses in Tyk2-deficient mice

scientific article

Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity

scientific article published in December 2003

Phylogeny, recombination and expression of porcine endogenous retrovirus gamma2 nucleotide sequences

scientific article published on April 2006

Phylotype-level 16S rRNA analysis reveals new bacterial indicators of health state in acute murine colitis

scientific article

Polymorphic DNA microsatellites in the domestic pigeon, Columba livia var. domestica

scientific article published on 01 March 2000

Polymorphic microsatellite markers in the outbred CFW and ICR stocks for the generation of speed congenic mice on C57BL/6 background

Porcine 11beta-hydroxysteroid dehydrogenase type 2 isoform: complete coding sequence and polymorphisms.

scientific article published in May 2003

Pronounced segregation of donor mitochondria introduced by bovine ooplasmic transfer to the female germ-line

scientific article published on 2 December 2009

Proviral load determination of different feline immunodeficiency virus isolates using real-time polymerase chain reaction: influence of mismatches on quantification.

scientific article

Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias

scientific article published on December 2011

Rapid and sensitive detection of enhanced green fluorescent protein expression in paraffin sections by confocal laser scanning microscopy

scientific article

Recombination analysis of human-tropic porcine endogenous retroviruses

scientific article published on October 2003

Reduced body growth and excessive incisor length in insertional mutants mapping to mouse Chromosome 13.

scientific article published in September 2002

Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins

scientific article published on 18 November 2013

Response to interferons and antibacterial innate immunity in the absence of tyrosine-phosphorylated STAT1

scientific article published on 12 February 2016

Role of Tyk-2 in Th9 and Th17 cells in allergic asthma

scientific article

Route of Infection Determines the Impact of Type I Interferons on Innate Immunity to Listeria monocytogenes

scientific article

STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.

scientific article

STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity

scientific article

STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

scientific article

STAT5BN642H is a driver mutation for T cell neoplasia

scientific article published on 4 December 2017

Second hit influences the interaction between tumor cells and the immune system in a murine model of Burkitt's lymphoma

scientific article published on 5 November 2008

Selective contribution of Tyk2 to cell activation by lipopolysaccharide.

scientific article

Short communication: Identification and characterization of multiple splicing forms of bovine prochymosin mRNA.

scientific article published in December 2002

Short communication: Single tube allele specific (STAS) PCR for direct determination of the mutation in the porcine ryanodine receptor gene associated with malignant hyperthermia

article

Signal transduction. Just another signalling pathway.

scientific article published on November 1994

Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection

scientific article published on 02 December 2021

Somatic gene transfer into the lactating ovine mammary gland

scientific article

Species-Specific Alternative Splicing of Transgenic RNA in the Mammary Glands of Pigs, Rabbits, and Mice

scientific article published in April 1999

Species-specific regulation of Toll-like receptor 3 genes in men and mice.

scientific article published on 2 April 2003

Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression

scientific article

Stable long-term germ-line transmission of transgene integration sites in mice

scientific article published on 01 February 1999

Stable production of human insulin-like growth factor 1 (IGF-1) in the milk of hemi- and homozygous transgenic rabbits over several generations

scientific article published in 1998

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2.

scientific article published on 31 January 2008

Studying human pathogens in animal models: fine tuning the humanized mouse

scientific article

Superantigen expression is driven by both mouse mammary tumor virus long terminal repeat-associated promoters in transgenic mice

scientific article published on March 2000

TYK2 AND SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 CONTRIBUTE TO INTESTINAL I/R INJURY

TYK2 in Tumor Immunosurveillance

scientific article published on 08 January 2020

TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis

scientific article published on 01 April 2020

TYK2 is a key regulator of the surveillance of B lymphoid tumors

TYK2 kinase activity is required for functional type I interferon responses in vivo

scientific article (publication date: 2012)

TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia

scientific article published on 7 March 2013

TYK2: An Upstream Kinase of STATs in Cancer

scientific article published on 05 November 2019

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment

article

The Continuing Fascination with Jaks and Stats: An Introduction

The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity

scientific article published on 26 November 2018

The TSC-mTOR signaling pathway regulates the innate inflammatory response

scientific article

The anti-inflammatory potency of dexamethasone is determined by the route of application in vivo

scientific article published on 12 January 2010

The cooperating mutation or "second hit" determines the immunologic visibility toward MYC-induced murine lymphomas

scientific article published on 30 August 2011

The different functions of Stat5 and chromatin alteration through Stat5 proteins

scientific article

The good and the bad faces of STAT1 in solid tumours

scientific article

The impact of shelf life on exposure as revealed from quality control data associated with the quargel outbreak.

scientific article

The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS).

scientific article

The porcine glucocorticoid receptor: sequencing a 2.1 kb cDNA fragment and raising specific polyclonal antibodies for western blotting, immunoprecipitation and immunohistochemistry

article published in 2001

The regulation of inflammation by interferons and their STATs

scientific article

The tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infection

scientific journal article

The yin and yang of type I interferon activity in bacterial infection

scientific article

Tissue concentration, mRNA expression and stimulation of IGF-I in luteal tissue during the oestrous cycle and pregnancy of cows

scientific article published on 01 November 1990

Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes

scientific article

Transgenic Modification of Production Traits in Farm Animals

article

Transgenic offspring by transcaryotic implantation of transgenic ovaries into normal mice

scientific article published in 1990

Transgenic pigs carrying cDNA copies encoding the murine Mx1 protein which confers resistance to influenza virus infection

scientific article published in November 1992

Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias

scientific article published on 01 August 2000

Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overload

scientific article published in August 2003

Tristetraprolin is required for full anti-inflammatory response of murine macrophages to IL-10.

scientific article published on 19 June 2009

Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation

scientific article published on 20 December 2011

Trypanosomosis: potential driver of selection in African cattle

scientific article published on 21 April 2015

Type I IFN are host modulators of strain-specific Listeria monocytogenes virulence

article by Benjamin Reutterer et al published May 2008 in Cellular Microbiology

Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue.

scientific article

Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice

scientific article published on 17 June 2016

Type I interferons as mediators of immune adjuvants for T- and B cell-dependent acquired immunity

scientific article published on December 2009

Type I interferons have opposing effects during the emergence and recovery phases of colitis.

scientific article

Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections

scientific article

Tyrosinase gene variants in different rabbit strains.

scientific article

Tyrosine kinase 2 - Surveillant of tumours and bona fide oncogene.

scientific article

Tyrosine kinase 2 controls IL-1ß production at the translational level

scientific article published on 16 August 2010

Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27

scientific article

UME6is a crucial downstream target of other transcriptional regulators of true hyphal development inCandida albicans

article

YAC transgenesis in farm animals: rescue of albinism in rabbits

scientific article published on 01 May 1996

p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin

scientific article published on 11 January 2013

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