Search filters

List of works by Michael A. Laflamme

Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria.

scientific article published on 29 April 2010

Aortic dissection in osteogenesis imperfecta: case report and review of the literature.

scientific article published on 20 April 2012

Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes

scientific article published on 23 June 2013

Cardiac repair with pluripotent stem cell-derived cardiomyocytes: Proof of concept but new challenges.

scientific article published on 3 June 2017

Cardiogenic differentiation and transdifferentiation of progenitor cells

scientific article

Cell-based delivery of dATP via gap junctions enhances cardiac contractility

scientific article published on 26 April 2014

Cell-based therapy for myocardial ischemia and infarction: pathophysiological mechanisms.

scientific article published on January 2007

Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo.

scientific article

Differentiation of cardiomyocytes from human embryonic stem cells is accompanied by changes in the extracellular matrix production of versican and hyaluronan.

scientific article published on October 2010

Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells.

scientific article

Electrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct Model

scientific article published on 10 February 2014

Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts

scientific article published on 01 April 2002

Exposure to phthalates affects calcium handling and intercellular connectivity of human stem cell-derived cardiomyocytes

scientific article

Extracardiac progenitor cells repopulate most major cell types in the transplanted human heart.

scientific article published in November 2005

HLA Class I Depleted hESC as a Source of Hypoimmunogenic Cells for Tissue Engineering Applications

scientific article

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

scientific article published on September 2012

Human embryonic stem cell-derived cardiomyocytes engraft but do not alter cardiac remodeling after chronic infarction in rats

scientific article

Human embryonic stem cells and cardiac repair

scientific article published on 26 July 2008

Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model

scientific article published on 28 March 2012

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.

scientific article

Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening

scientific article published on 19 December 2016

Human pluripotent stem cells: Prospects and challenges as a source of cardiomyocytes for in vitro modeling and cell-based cardiac repair.

scientific article

Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells.

scientific article

Introduction to JCPT Focused Issue on "Stem Cells and Cardiac Regenerative Medicine"

scientific article published on 17 June 2014

Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes

scientific article

Letter by Murry et al regarding article, "Embryonic stem cell-derived cardiac myocytes are not ready for human trials".

scientific article published on October 2014

Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes

scientific article

Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts.

scientific article

Methods for the derivation and use of cardiomyocytes from human pluripotent stem cells

scientific article published on January 2011

Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering

scientific article published on 21 June 2017

Mitochondrial Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes.

scientific article published on 27 February 2017

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

scientific article

Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.

scientific article

Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells

scientific article published on 29 July 2010

Optical Method to Quantify Mechanical Contraction and Calcium Transients of Human Pluripotent Stem Cell-Derived Cardiomyocytes.

scientific article published on 31 May 2017

Pluripotent stem cell derived cardiomyocytes for cardiac repair

scientific article

Proangiogenic scaffolds as functional templates for cardiac tissue engineering.

scientific article

Programming cells for cardiac repair.

scientific article

Regenerating the heart

scientific article

Ribonucleotide reductase-mediated increase in dATP improves cardiac performance via myosin activation in a large animal model of heart failure

scientific article published on 15 April 2015

Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells

scientific article published on 5 April 2013

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

scientific article

Targeting survival pathways to create infarct-spanning bridges of human embryonic stem cell-derived cardiomyocytes

scientific article

The cardiomyocyte lineage is critical for optimization of stem cell therapy in a mouse model of myocardial infarction

scientific article

Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response.

scientific article published on 6 February 2007