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List of works by Paula Gomes

"Clicking" an Ionic Liquid to a Potent Antimicrobial Peptide: On the Route towards Improved Stability

scientific article published on 26 August 2020

"Recycling" classical drugs for malaria

scientific article published on 20 October 2014

11(th) National Meeting of Organic Chemistry and 4(th) Meeting of Therapeutic Chemistry

scientific article published on 17 March 2016

A 17-mer Membrane-Active MSI-78 Derivative with Improved Selectivity toward Bacterial Cells

scientific article published in July 2015

A Quinacrine Analogue Selective Against Gastric Cancer Cells: Insight from Biochemical and Biophysical Studies

scientific article published on 14 November 2016

A biocompatible hybrid material with simultaneous calcium and strontium release capability for bone tissue repair

scientific article published on 30 January 2016

A minocycline-releasing PMMA system as a space maintainer for staged bone reconstructions-in vitro antibacterial, cytocompatibility and anti-inflammatory characterization

scientific article published on 23 March 2017

A novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates.

scientific article published on 21 February 2018

AMP-Chitosan Coating with Bactericidal Activity in the Presence of Human Plasma Proteins

scientific article published on 03 July 2020

Acylation of the S4-PV cell-penetrating peptide as a means of enhancing its capacity to mediate nucleic acid delivery: Relevance of peptide/lipid interactions

scientific article published on 04 October 2018

Affinity-Triggered Assemblies Based on a Designed Peptide-Peptide Affinity Pair

scientific article published on 08 August 2019

Aminoglutethimide-imprinted xerogels in bulk and spherical formats, based on a multifunctional organo-alkoxysilane precursor

scientific article published on 3 November 2015

Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones

scientific article published on 3 December 2007

Anti-tumoral activity of imidazoquines, a new class of antimalarials derived from primaquine

scientific article

Antigenicity modulation upon peptide cyclization: application to the GH loop of foot-and-mouth disease virus strain C1-Barcelona.

scientific article published in May 2001

Antimicrobial coatings prepared from Dhvar-5-click-grafted chitosan powders

scientific article published on 05 December 2018

Antimicrobial peptides: a new class of antimalarial drugs?

scientific article

Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78.

scientific article published on 10 February 2015

Bacteria-targeted biomaterials: Glycan-coated microspheres to bind Helicobacter pylori.

scientific article published on 21 January 2016

Biomimetic mineralization on a macroporous cellulose-based matrix for bone regeneration

scientific article published on 19 September 2013

Bionanoconjugates of tyrosinase and peptide-derivatised gold nanoparticles for biosensing of phenolic compounds

Bisphosphonates induce the osteogenic gene expression in co-cultured human endothelial and mesenchymal stem cells.

scientific article published on 31 October 2013

Bone Cells Dynamics during Peri-Implantitis: a Theoretical Analysis

scientific article

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

scientific article published on 30 June 2018

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5

scientific article published on 30 June 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6

scientific article published on 28 December 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4

scientific article published on 31 December 2018

Carcinogenic liver fluke Opisthorchis viverrini oxysterols detected by LC-MS/MS survey of soluble fraction parasite extract.

scientific article published on 20 August 2013

Cell-induced response by tetracyclines on human bone marrow colonized hydroxyapatite and Bonelike.

scientific article

Characterization of Sensory Properties of Flavanols--A Molecular Dynamic Approach

scientific article published on 01 May 2015

Characterization of hLF1-11 immobilization onto chitosan ultrathin films, and its effects on antimicrobial activity

scientific article published on 12 March 2014

Chloroquine Analogues as Leads against Pneumocystis Lung Pathogens

scientific article published on 24 October 2018

Cinnamic Acid Conjugates in the Rescuing and Repurposing of Classical Antimalarial Drugs

scientific article published on 24 December 2019

Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum

scientific article published on 29 June 2012

Clinical Application of AMPs

scientific article published on 01 January 2019

Comparison of the Efficiency of Complexes Based on S413-PV Cell-Penetrating Peptides in Plasmid DNA and siRNA Delivery ⬇️

scientific article published on June 10, 2013

Coupling the Antimalarial Cell Penetrating Peptide TP10 to Classical Antimalarial Drugs Primaquine and Chloroquine Produces Strongly Hemolytic Conjugates

scientific article published on 12 December 2019

Coupling the cell-penetrating peptides transportan and transportan 10 to primaquine enhances its activity against liver-stage malaria parasites

scholarly article by Luísa Aguiar et al published 1 February 2019 in MedChemComm

Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces.

scientific article

Cross-species comparison of mammalian saliva using an LC-MALDI based proteomic approach

scientific article published on 9 March 2015

Cyclization-activated prodrugs.

scientific article

Cyclization-activated prodrugs. Synthesis, reactivity and toxicity of dipeptide esters of paracetamol

scientific article published in March 2005

Cytotoxicity evaluation of nanocrystalline diamond coatings by fibroblast cell cultures.

scientific article published on 10 September 2008

Defensins in the oral cavity: distribution and biological role.

scientific article

Development of hydroxyapatite nanoparticles loaded with folic acid to induce osteoblastic differentiation.

scientific article published on 13 November 2016

Dhvar5 antimicrobial peptide (AMP) chemoselective covalent immobilization results on higher antiadherence effect than simple physical adsorption.

scientific article published on 18 March 2015

Diels-Alder functionalized carbon nanotubes for bone tissue engineering: in vitro/in vivo biocompatibility and biodegradability.

scientific article published on 30 April 2015

Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity

scientific article

Direct kinetic assay of interactions between small peptides and immobilized antibodies using a surface plasmon resonance biosensor

scientific article published on 01 January 2002

Direct single-step surface plasmon resonance analysis of interactions between small peptides and immobilized monoclonal antibodies

scientific article published on 01 February 2000

Dynamics of an antibiotic oligopeptide

article

Effect of Sterilization Methods on Electrospun Poly(lactic acid) (PLA) Fiber Alignment for Biomedical Applications.

scientific article

Effect of surface coating on the biodistribution profile of gold nanoparticles in the rat.

scientific article published on 16 September 2011

Effect of therapeutic levels of doxycycline and minocycline in the proliferation and differentiation of human bone marrow osteoblastic cells

scientific article published in December 2006

Effects of novel triple-stage antimalarial ionic liquids on lipid membrane models

scientific article published on 3 July 2017

Efficacy and Cytotoxicity of Binary Mixtures as Root Canal Filling Solvents

scientific article published on 21 July 2020

Electrospray ionization mass spectrometry as a valuable tool in the characterization of novel primaquine peptidomimetic derivatives

scientific article published in January 2009

Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine

scientific article published in July 2008

Encapsulated bacteriophages in alginate-nanohydroxyapatite hydrogel as a novel delivery system to prevent orthopedic implant-associated infections

scientific article published on 17 December 2019

EndoProteoFASP as a Tool to Unveil the Peptidome-Protease Profile: Application to Salivary Diagnostics

scientific article published in January 2018

Energetics and partition of two cecropin-melittin hybrid peptides to model membranes of different composition

scientific article published on 21 November 2007

Equisetum arvense hydromethanolic extracts in bone tissue regeneration: in vitro osteoblastic modulation and antibacterial activity.

scientific article published in June 2012

Evaluation of human osteoblastic cell response to plasma-sprayed silicon-substituted hydroxyapatite coatings over titanium substrates

scientific article published on 01 August 2010

Gemcitabine anti-proliferative activity significantly enhanced upon conjugation with cell-penetrating peptides.

scientific article

Grafting Techniques towards Production of Peptide-Tethered Hydrogels, a Novel Class of Materials with Biomedical Interest

scientific article published on 21 October 2015

Growth and phenotypic expression of human endothelial cells cultured on a glass-reinforced hydroxyapatite.

scientific article

Harnessing snake venom phospholipases A2 to novel approaches for overcoming antibiotic resistance

scientific article published on 26 September 2018

Heparan sulphate mediates swine vesicular disease virus attachment to the host cell

scientific article published on March 2004

Hydration water and peptide dynamics--two sides of a coin. A neutron scattering and adiabatic calorimetry study at low hydration and cryogenic temperatures

scientific article

Identification of T-cell epitopes in nonstructural proteins of foot-and-mouth disease virus.

scientific article published on April 2001

Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials

scientific article published in February 2005

Imidazolidin-4-one peptidomimetic derivatives of primaquine: synthesis and antimalarial activity

scientific article published on 23 May 2008

Imidazolium-based functional monomers for the imprinting of the anti-inflammatory drug naproxen: comparison of acrylic and sol-gel approaches

scientific article published on 9 September 2013

Imidazoquines as antimalarial and antipneumocystis agents

scientific article published on December 2009

ImmunoPEGliposomes for the targeted delivery of novel lipophilic drugs to red blood cells in a falciparum malaria murine model

scientific article

In Vitro Evaluation of Five Antimicrobial Peptides against the Plant Pathogen Erwinia amylovora

scientific article published in 2021

In the trail of a new bio-sensor for measuring strain in bone: osteoblastic biocompatibility.

scientific article published on 2 April 2011

In vitro efficiency of 9-(N-cinnamoylbutyl)aminoacridines against blood- and liver-stage malaria parasites

scientific article

In vitro evaluation of Portuguese propolis and floral sources for antiprotozoal, antibacterial and antifungal activity

scientific article published on 31 May 2013

In vivo assessment of a new multifunctional coating architecture for improved Mg alloy biocompatibility

scientific article

In vivo tissue response and antibacterial efficacy of minocycline delivery system based on polymethylmethacrylate bone cement

scientific article published on 01 September 2018

Incorporation of glass-reinforced hydroxyapatite microparticles into poly(lactic acid) electrospun fibre mats for biomedical applications.

scientific article

Increased DNA damage and cell death on exfoliated buccal epithelial cells upon CPAP therapy with oro-nasal interface

scientific article published on 3 November 2016

Insights into the Membranolytic Activity of Antimalarial Drug-Cell Penetrating Peptide Conjugates

scientific article published on 22 December 2020

Interaction and lipid-induced conformation of two cecropin-melittin hybrid peptides depend on peptide and membrane composition

scientific article published in September 2005

Interaction between Wine Phenolic Acids and Salivary Proteins by Saturation-Transfer Difference Nuclear Magnetic Resonance Spectroscopy (STD-NMR) and Molecular Dynamics Simulations.

scientific article

Ionic liquids for Topical Delivery in Cancer

scientific article published on 01 January 2019

Killing of Mycobacterium avium by lactoferricin peptides: improved activity of arginine- and D-amino-acid-containing molecules

scientific article

Levofloxacin-loaded bone cement delivery system: highly effective against intracellular bacteria and Staphylococcus aureus biofilms.

scientific article

Mass spectrometry techniques in the survey of steroid metabolites as potential disease biomarkers: a review

scientific article

Mastocytosis: oral implications of a rare disease.

scientific article published on 30 December 2010

Melanoma targeting with alpha-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: effect of cyclization on tumor-seeking properties.

scientific article published on 8 January 2008

Membrane structure and interactions of a short Lycotoxin I analogue

scientific article published on April 2008

Microanalysis of Bioactive Samarium Doped Glass-Reinforced Hydroxyapatite

scientific article published on 01 August 2015

Model Amphipathic Peptide Coupled with Tacrine to Improve Its Antiproliferative Activity

scientific article published on 29 December 2020

Molecular analysis of peptides from the GH loop of foot-and-mouth disease virus C-S30 using surface plasmon resonance: a role for kinetic rate constants.

scientific article published in November 2000

Multifunctional PLLA-ceramic fiber membranes for bone regeneration applications.

scientific article published on 12 May 2017

Multifunctional carbon nanotube/bioceramics modulate the directional growth and activity of osteoblastic cells.

scientific article published on May 2014

N-Cinnamoylation of Antimalarial Classics: Effects of Using Acyl Groups Other than Cinnamoyl toward Dual-Stage Antimalarials

scientific article published on 2 June 2015

N-acetylcysteine-functionalized coating avoids bacterial adhesion and biofilm formation.

scientific article published on 12 December 2017

N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads

scientific article published on 8 January 2013

N-cinnamoylation of antimalarial classics: quinacrine analogues with decreased toxicity and dual-stage activity

scientific article published on 27 December 2013

Nano-hydroxyapatite in oral care cosmetics: characterization and cytotoxicity assessment

scientific article published on 30 July 2019

Nanocrystalline diamond: In vitro biocompatibility assessment by MG63 and human bone marrow cells cultures

scientific article published in October 2008

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins

scientific article published on 4 May 2017

New times, new trends for ethionamide: In vitro evaluation of drug-loaded thermally carbonized porous silicon microparticles.

scientific article

New titanium and titanium/hydroxyapatite coatings on ultra-high-molecular-weight polyethylene-in vitro osteoblastic performance

scientific article published on 4 June 2010

Nitric Oxide Release from Antimicrobial Peptide Hydrogels for Wound Healing

scientific article published in 2018

Novel cerium doped glass-reinforced hydroxyapatite with antibacterial and osteoconductive properties for bone tissue regeneration.

scientific article published on 21 September 2015

Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: towards the development of potential dual action antimalarials

scientific article published on 28 May 2012

Novel potent metallocenes against liver stage malaria

scientific article published on 12 December 2011

Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior.

scientific article published on 25 November 2017

PDMS-SiO2-TiO2-CaO hybrid materials - Cytocompatibility and nanoscale surface features.

scientific article published on 24 March 2016

PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity

PRIMACINS, N-cinnamoyl-primaquine conjugates, with improved liver-stage antimalarial activity

Peptide-Based Drugs and Drug Delivery Systems.

scientific article published on 8 December 2017

Phenolic Profiling of Portuguese Propolis by LC–MS Spectrometry: Uncommon Propolis Rich in Flavonoid Glycosides ⬇️

scientific article published on November 22, 2012

Phenolic quantification and botanical origin of Portuguese propolis

article

Physicochemical and toxicological properties of novel amino acid-based amphiphiles and their spontaneously formed catanionic vesicles

scientific article published in April 2009

Plasma catecholamines during an ultrarapid heroin detoxification

scientific article published on 01 September 2000

Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents

scientific article published on 24 August 2019

Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs

scientific article published on 29 January 2009

Primaquine revisited six decades after its discovery

scientific article

Probing degeneracy in antigen-antibody recognition at the immunodominant site of foot-and-mouth disease virus.

scientific article published in May 2002

Processing strategies for smart electroconductive carbon nanotube-based bioceramic bone grafts.

scientific article published on 12 March 2014

Radiochemical and biological evaluation of novel153Sm/166Ho-amino acid-chitosan complexes

Recycling antimalarial leads for cancer: Antiproliferative properties of N-cinnamoyl chloroquine analogues

scientific article published on 21 October 2013

Relevance of the sterilization-induced effects on the properties of different hydroxyapatite nanoparticles and assessment of the osteoblastic cell response.

scientific article

Rodent models in bone-related research: the relevance of calvarial defects in the assessment of bone regeneration strategies.

scientific article published on 14 December 2010

S4(13)-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA.

scientific article

S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: implications for cell internalization

scientific article published on 31 December 2011

Samarium doped glass-reinforced hydroxyapatite with enhanced osteoblastic performance and antibacterial properties for bone tissue regeneration

scientific article published on 31 July 2014

Schistosoma haematobium: identification of new estrogenic molecules with estradiol antagonistic activity and ability to inactivate estrogen receptor in mammalian cells

scientific article published on 12 June 2010

Selective albumin-binding surfaces modified with a thrombin-inhibiting peptide.

scientific article published on 5 December 2013

Silicate and borate glasses as composite fillers: a bioactivity and biocompatibility study

scientific article published on 10 May 2011

Smart electroconductive bioactive ceramics to promote in situ electrostimulation of bone

scientific article published on 27 January 2015

Spontaneous vesicle formation in catanionic mixtures of amino acid-based surfactants: chain length symmetry effects.

scientific article

Striking HIV-1 Entry by Targeting HIV-1 gp41. But, Where Should We Target?

scientific article published on 19 January 2016

Structure and function of a novel antioxidant peptide from the skin of tropical frogs

scientific article

Structure-activity relationships for dipeptide prodrugs of acyclovir: implications for prodrug design

scientific article published on 11 September 2008

Structure-function studies of BPP-BrachyNH2 and synthetic analogues thereof with Angiotensin I-Converting Enzyme

scientific article published on 7 August 2017

Structure/property relationships for the thermotropic behavior of lysine-based amphiphiles: from hexagonal to smectic phases

scientific article published in November 2008

Tethering antimicrobial peptides onto chitosan: Optimization of azide-alkyne "click" reaction conditions.

scientific article published on 17 February 2017

The 1st Baltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 2016. Summary and Consensus Statements: Group I - Peri-Implantitis Aetiology, Risk Factors and Pathogenesis

scientific article published on July 2016

The Osteogenic Priming of Mesenchymal Stem Cells is Impaired in Experimental Diabetes

scientific article

The biomaterial-mediated healing of critical size bone defects in the ovariectomized rat.

scientific article

The diagnosis of eating disorders through mid-infrared spectroscopy of the gingival crevicular fluid: a pilot trial

The effects of intense pulsed light in a mouse model of skin carcinogenesis

scientific article published on 17 November 2015

Toward the definition of a peptidome signature and protease profile in chronic periodontitis

scientific article published on 8 February 2015

Toward the discovery of inhibitors of babesipain-1, a Babesia bigemina cysteine protease: in vitro evaluation, homology modeling and molecular docking studies

scientific article

Towards a Sustainable Management of the Spotted-Wing Drosophila: Disclosing the Effects of Two Spider Venom Peptides on Drosophila suzukii

scientific article published in 2023

Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: an oestrogen-DNA adducts mediated pathway?

scientific article published on 20 December 2012

Unanticipated stereoselectivity in the reaction of primaquine alpha-aminoamides with substituted benzaldehydes: a computational and experimental study

scientific article

Uncovering the molecular networks in periodontitis ⬇️

scientific article published on 14 July 2014

Unravelling a Mechanism of Action for a Cecropin A-Melittin Hybrid Antimicrobial Peptide: The Induced Formation of Multilamellar Lipid Stacks

scientific article

Urinary estrogen metabolites and self-reported infertility in women infected with Schistosoma haematobium

scientific article (publication date: 2014)

Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

scientific article

endoProteoFASP: a novel FASP approach to profile salivary peptidome and disclose salivary proteases.

scientific article

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