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List of works by Gavin Kelly

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice

scientific article published on 03 September 2019

A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws.

scientific article

A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast

scientific article published on 22 February 2018

Alteration of cell-cell and cell-matrix adhesion in urothelial cells: an oncogenic mechanism for mutant FGFR3. ⬇️

scientific article published on 15 September 2014

Antiretroviral Treatment-Induced Decrease in Immune Activation Contributes to Reduced Susceptibility to Tuberculosis in HIV-1/Mtb Co-infected Persons

scientific article published on 05 March 2021

Array-based DNA methylation profiling in follicular lymphoma

scientific article published on 09 July 2009

Budding yeast Wapl controls sister chromatid cohesion maintenance and chromosome condensation

scientific article

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

scientific article published on 29 April 2020

Cdc14 and PP2A Phosphatases Cooperate to Shape Phosphoproteome Dynamics during Mitotic Exit

scientific article published on 01 November 2019

Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells

scientific article published on 05 April 2022

Characterisation of the Toxoplasma gondii tyrosine transporter and its phosphorylation by the calcium-dependent protein kinase 3

scientific article published on 25 November 2018

Cohesin relocation from sites of chromosomal loading to places of convergent transcription

scientific article published on 30 June 2004

Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling

scientific article published on August 2010

Condensin-dependent rDNA decatenation introduces a temporal pattern to chromosome segregation

scientific article published in July 2008

Deficits in axonal transport precede ALS symptoms in vivo

scientific article

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies

scientific article published on 22 May 2012

Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation.

scientific article published on 4 February 2006

Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease

scientific article

ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription

scientific article published on 26 February 2017

Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach

scientific article published on 28 September 2015

Expression of HIF-1alpha, HIF-2alpha (EPAS1), and their target genes in paraganglioma and pheochromocytoma with VHL and SDH mutations

scientific article published on 5 September 2006

Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial

scientific article published on 23 May 2015

FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts

scientific article

Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy

scientific article published on 28 September 2009

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.

scientific article

Gene expression profile of quinacrine-cured prion-infected mouse neuronal cells

scientific article published on 25 November 2007

Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells

scientific article

Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target

scientific article

Heat shock induces premature transcript termination and reconfigures the human transcriptome

scientific article published on 02 February 2022

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

scientific article published on 30 August 2005

Identification of cis-acting sites for condensin loading onto budding yeast chromosomes

scientific article

Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation.

scientific article published on January 2007

Imaging macrophage chemotaxis in vivo: studies of microtubule function in zebrafish wound inflammation

scientific article published in July 2006

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation

scientific article published on 17 March 2016

Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment

scientific article

Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection

scientific article published on 13 January 2020

Initiation of high frequency multi-drug resistance following kinase targeting by siRNAs

scientific article published on 4 June 2007

Mechanistic interpretation of promoter-proximal peaks and RNAPII density maps.

scientific article

Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27-induced Charcot Marie Tooth Disease

scientific article published on 8 June 2017

Multiomic Analysis of the UV-Induced DNA Damage Response ⬇️

scientific article

Mutation of cancer driver MLL2 results in transcription stress and genome instability.

scientific article published on February 2016

RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology

scientific article published on 10 March 2011

RECQL5 controls transcript elongation and suppresses genome instability associated with transcription stress

scientific article

Reactive astrocytes in ALS display diminished intron retention

scientific article published on 01 April 2021

Regulation of the localisation and function of the oncogene LYRIC/AEG-1 by ubiquitination at K486 and K491.

scientific article published on 24 January 2014

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

scientific article

Single nucleotide polymorphism array analysis defines a specific genetic fingerprint for well-differentiated cutaneous SCCs

scientific article published on 8 January 2009

Site recognition and substrate screens for PKN family proteins

scientific article

The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

scientific article published on 19 June 2019

The Scc2-Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions

scientific article

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

scientific article published on 16 December 2019

Tumour-suppression function of KLF12 through regulation of anoikis.

scientific article published on 12 October 2015

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene

scientific article published on 16 February 2017

Vitamin D regulates microbiome-dependent cancer immunity

scientific article published on 26 April 2024

miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance

scientific article published on 15 August 2013

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