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List of works by Eriko Takano

A 'Plug and Play' Platform for the Production of Diverse Monoterpene Hydrocarbon Scaffolds in Escherichia coli. ⬇️

scientific article published in June 2016

A Toolbox for Diverse Oxyfunctionalisation of Monoterpenes

scientific article published in Scientific Reports

A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor

scientific article published in April 2005

A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor ⬇️

scientific article

A complex role for the gamma-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2).

scientific article

A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2).

scientific article published on 29 September 2006

A rare leucine codon in adpA is implicated in the morphological defect of bldA mutants of Streptomyces coelicolor

scientific article published in October 2003

A single amino acid substitution in region 1.2 of the principal sigma factor of Streptomyces coelicolor A3(2) results in pleiotropic loss of antibiotic production

scientific article published on 01 September 2000

A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis

scientific article

A transatlantic perspective on 20 emerging issues in biological engineering.

scientific article published on 14 November 2017

A turning point for natural product discovery--ESF-EMBO research conference: synthetic biology of antibiotic production

scientific article published on 8 February 2012

An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

scientific article published on 08 June 2018

An automated pipeline for the screening of diverse monoterpene synthase libraries

Analysis of two additional signaling molecules in Streptomyces coelicolor and the development of a butyrolactone-specific reporter system ⬇️

scientific article published in September 2009

Application of protein N-terminal amidase in enzymatic synthesis of dipeptides containing acidic amino acids specifically at the N-terminus ⬇️

scientific article published on December 4, 2012

Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli

scientific article published on 18 July 2019

Bacterial Microcompartments: Biomaterials for Synthetic Biology-Based Compartmentalization Strategies

scholarly article by Ashley Chessher et al published 26 May 2015 in ACS biomaterials science & engineering

Bioengineering horizon scan 2020

scientific article published on 29 May 2020

Bioinformatics for the synthetic biology of natural products: integrating across the Design-Build-Test cycle

scientific article published on 17 May 2016

Butyrolactone signalling circuits for synthetic biology

scientific article published on 08 July 2015

Chapter 6. Regulation of antibiotic production by bacterial hormones

scientific article published in January 2009

Characterisation of a natural variant of the γ-butyrolactone signalling receptor

scientific article

Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism

article

Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters

article

Computational tools for the synthetic design of biochemical pathways

scientific article published on 23 January 2012

Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp.

scientific article

Convergent transcription in the butyrolactone regulon in Streptomyces coelicolor confers a bistable genetic switch for antibiotic biosynthesis

scientific article

Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2).

scientific article published on 6 May 2010

Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2) ⬇️

scientific article published on 8 December 2010

Design-based re-engineering of biosynthetic gene clusters: plug-and-play in practice

scientific article

Detecting sequence homology at the gene cluster level with MultiGeneBlast

scientific article published on 14 February 2013

Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli

scientific article published on 27 May 2015

Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms

article

Exploring novel bacterial terpene synthases

scientific article published on 30 April 2020

Exploring the metabolic state of microorganisms using metabolomics

scientific article

Fine-tuning the regulation of Cas9 expression levels for efficient CRISPR-Cas9 mediated recombination in Streptomyces

scientific article published on 04 May 2020

Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block.

scientific article published on 9 March 2015

Gamma-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation

scientific article

Genome-based phylogenetic analysis of Streptomyces and its relatives

scientific article published on 3 December 2009

Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus ⬇️

scientific article published on 2 November 2010

Genome-wide inference of regulatory networks in Streptomyces coelicolor

scientific article

Highly multiplexed, fast and accurate nanopore sequencing for verification of synthetic DNA constructs and sequence libraries

scientific article published on 29 October 2019

Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2) ⬇️

article

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters ⬇️

scientific article published in July 2014

Integrated Probabilistic Annotation: A Bayesian-Based Annotation Method for Metabolomic Profiles Integrating Biochemical Connections, Isotope Patterns, and Adduct Relationships

scientific article published on 11 September 2019

Judging synthetic biology risks

scientific article published in Science

Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli

scientific article published on 07 January 2019

Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor

scientific article

Metabolomic analysis of a synthetic metabolic switch in Streptomyces coelicolor A3(2)

article

Metabolomic characterization of the salt stress response in Streptomyces coelicolor ⬇️

scientific article

Metabolomics for secondary metabolite research

scientific article

Metabolomics methods for the synthetic biology of secondary metabolism

scientific article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Modeling challenges in the synthetic biology of secondary metabolism

scientific article published on 20 May 2013

MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models

scientific article

Natural Product Biosynthesis in Escherichia coli: Mentha Monoterpenoids

scientific article published on 24 March 2016

Natural Products: Tools and More Special Issue

Noncoding RNA of glutamine synthetase I modulates antibiotic production in Streptomyces coelicolor A3(2).

scientific article

Orthogonal Regulatory Circuits for Escherichia coli Based on the γ-Butyrolactone System of Streptomyces coelicolor. ⬇️

scientific article published on 6 March 2018

Output ordering and prioritisation system (OOPS): ranking biosynthetic gene clusters to enhance bioactive metabolite discovery

scientific article published on 18 December 2017

Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products

scientific article

Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor

scientific article

Purification and properties of a prokaryote type glutamine synthetase from the bialaphos producer Streptomyces hygroscopicus SF1293

Purification and structural determination of SCB1, a gamma-butyrolactone that elicits antibiotic production in Streptomyces coelicolor A3(2) ⬇️

scientific article

Replacement of Streptomyces hygroscopicus genomic segments with in vitro altered DNA sequences

scientific article published in February 1988

Ribosylhopane, a novel bacterial hopanoid, as precursor of C35 bacteriohopanepolyols in Streptomyces coelicolor A3(2) ⬇️

scientific article

SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals

scientific article

ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesize -butyrolactones

scientific article published on 01 May 2007

SelProm: A Queryable and Predictive Expression Vector Selection Tool for Escherichia coli

scientific article published on 18 March 2019

Selenzyme: Enzyme selection tool for pathway design

Separating the wheat from the chaff: a prioritisation pipeline for the analysis of metabolomics datasets

scientific article published on 31 July 2011

Stationary-phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated

article

Steps towards the synthetic biology of polyketide biosynthesis

scientific article published on 07 January 2014

Stoffwechselwege vom Reißbrett: neue Ansätze der Naturstoffbiochemie

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.

scientific article published on 9 August 2017

Switchable foldamer ion channels with antibacterial activity

scientific article published on 04 June 2020

Synthetic Biology of Natural Products

scientific article

Synthetic Biology of Natural Products

scholarly article published 28 March 2014

Synthetic biology advances for pharmaceutical production

scientific article

The Border Sequence of the Balhimycin Biosynthesis Gene Cluster from Amycolatopsis balhimycina Contains bbr , Encoding a StrR-Like Pathway-Specific Regulator

article

The bialaphos biosynthetic genes of Streptomyces hygroscopicus: cloning and analysis of the genes involved in the alanylation step ⬇️

scientific article published in April 1988

The bialaphos resistance gene (bar) plays a role in both self-defense and bialaphos biosynthesis in Streptomyces hygroscopicus.

scientific article published in December 1988

The dynamic architecture of the metabolic switch in Streptomyces coelicolor.

scientific article

The future of industrial antibiotic production: from random mutagenesis to synthetic biology

scientific article published on July 2011

The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways

scientific article published on 12 July 2010

The “Three Cs” of Novel Antibiotic Discovery and Production through Synthetic Biology: Biosynthetic Gene Clusters, Heterologous Chassis, and Synthetic Microbial Consortia

article

Towards synthesis of monoterpenes and derivatives using synthetic biology

scientific article

Towards the sustainable discovery and development of new antibiotics

scientific article published in 2021

Transcriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2) ⬇️

scientific journal article

Unravelling the γ-butyrolactone network in Streptomyces coelicolor by computational ensemble modelling

scientific article published on 10 July 2020

antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

scientific article published on 3 June 2013

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

scientific article published on 6 May 2015

antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification

scientific article published on 28 April 2017

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

scientific article published on 14 June 2011

redD and actII-ORF4, pathway-specific regulatory genes for antibiotic production in Streptomyces coelicolor A3(2), are transcribed in vitro by an RNA polymerase holoenzyme containing sigma hrdD. ⬇️

scientific article published on June 1996

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