List of works - Florence O. McCarthy

7β-Hydroxysitosterol crosses the blood-brain barrier more favored than its substrate sitosterol in ApoE-/- mice

scientific article published on 17 March 2015

A mechanistic investigation into the microbial chiral inversion of 2-arylpropionic acids using deuterated derivatives of 2-phenylpropionic acid

Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria

scientific article published on 2 December 2015

Computer simulations reveal a novel nucleotide-type binding orientation for ellipticine-based anticancer c-kit kinase inhibitors

scientific article published on 29 August 2008

Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line

scientific article published on October 2010

Ellipticine derivative induces potent cytostatic effect in acute myeloid leukaemia cells

scientific article

Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics.

scientific article

Inhibitory Properties of Aldehydes and Related Compounds against Phytophthora infestans-Identification of a New Lead

scientific article published on 07 July 2020

Local bacteria affect the efficacy of chemotherapeutic drugs

scientific article

Novel 11-Substituted Ellipticines as Potent Anticancer Agents with Divergent Activity against Cancer Cells

scientific article published on 14 June 2019

Oxidized derivatives of dihydrobrassicasterol: cytotoxic and apoptotic potential in U937 and HepG2 cells

scientific article

Phytosterol Oxidation Products: Their Formation, Occurrence, and Biological Effects

Qualitative and quantitative comparison of the cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products

scientific article published on September 2005

Recent advances in Phytosterol Oxidation Products

scientific article published on 31 January 2014

Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells

scientific article published on 26 April 2012

Synthesis and biological evaluation of novel isoellipticine derivatives and salts

scientific article published on October 2012

Synthesis and characterization of stigmasterol oxidation products

scientific article published in January 2010

Synthesis and evaluation of novel ellipticines as potential anti-cancer agents

scientific article published on February 2013

Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents

scientific article published on 10 August 2012

Synthesis, isolation and characterisation of beta-sitosterol and beta-sitosterol oxide derivatives

scientific article

Vascular effects of oxysterols and oxyphytosterols in apoE -/- mice.

scientific article published on 26 February 2015

List of works by Florence O. McCarthy

7β-Hydroxysitosterol crosses the blood-brain barrier more favored than its substrate sitosterol in ApoE-/- mice

A mechanistic investigation into the microbial chiral inversion of 2-arylpropionic acids using deuterated derivatives of 2-phenylpropionic acid

Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria

Computer simulations reveal a novel nucleotide-type binding orientation for ellipticine-based anticancer c-kit kinase inhibitors

Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line

Ellipticine derivative induces potent cytostatic effect in acute myeloid leukaemia cells

Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics.

Inhibitory Properties of Aldehydes and Related Compounds against Phytophthora infestans-Identification of a New Lead

Local bacteria affect the efficacy of chemotherapeutic drugs

Novel 11-Substituted Ellipticines as Potent Anticancer Agents with Divergent Activity against Cancer Cells

Oxidized derivatives of dihydrobrassicasterol: cytotoxic and apoptotic potential in U937 and HepG2 cells

Phytosterol Oxidation Products: Their Formation, Occurrence, and Biological Effects

Qualitative and quantitative comparison of the cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products

Recent advances in Phytosterol Oxidation Products

Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells

Synthesis and biological evaluation of novel isoellipticine derivatives and salts

Synthesis and characterization of stigmasterol oxidation products

Synthesis and evaluation of novel ellipticines as potential anti-cancer agents

Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents

Synthesis, isolation and characterisation of beta-sitosterol and beta-sitosterol oxide derivatives

Vascular effects of oxysterols and oxyphytosterols in apoE -/- mice.