List of works - Joan K. Heath

A factor synthesized by rabbit periosteal fibroblasts stimulates bone resorption and collagenase production by connective tissue cells in vitro

article

A simple method allowing DIC imaging in conjunction with confocal microscopy.

scientific article

A33 antigen-deficient mice have defective colonic mucosal repair.

scientific article published in April 2010

Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish

scientific article published on 6 November 2008

Anterior mandibular displacement and condylar growth

scientific article published on 01 October 1982

Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis

scientific article

Biochemical and autoradiographical evidence that anterior mandibular displacement in the young growing rat does not stimulate cell proliferation or matrix formation at the mandibular condyle

article

Bypassing multidrug resistance in cancer cells with biodegradable polymer capsules

scientific article published on December 2010

CREB activity modulates neural cell proliferation, midbrain-hindbrain organization and patterning in zebrafish

scientific article published on 27 April 2007

Capsosomes with Multilayered Subcompartments: Assembly and Loading with Hydrophobic Cargo

Cellular Association and Cargo Release of Redox-Responsive Polymer Capsules Mediated by Exofacial Thiols

scientific article published on 02 August 2011

Characterization of posttranslational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium.

scientific article

Colony-Stimulating Factor-1 Promotes Clonogenic Growth of Normal Murine Colonic Crypt Epithelial Cells In Vitro

article

Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

scientific article

Detecting apoptosis during the formation of polarized intestinal epithelium in organ culture

scientific article published in July 2004

Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms

scientific article published on 19 April 2022

Dexamethasone regulation of parathyroid hormone-related protein (PTHrP) expression in a squamous cancer cell line.

scientific article published on May 1994

Efficient gene transfer into the epithelial cell layer of embryonic mouse intestine using low-voltage electroporation.

scientific article published in June 2004

Electrophoretic analysis of the novel antigen for the gastrointestinal-specific monoclonal antibody, A33.

scientific article published on March 1997

Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling

scientific article

Encapsulation of water-insoluble drugs in polymer capsules prepared using mesoporous silica templates for intracellular drug delivery

scientific article published on October 2010

Evidence for a direct effect of estrogen on bone cells in vitro.

scientific article published on January 1989

Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis.

scientific article

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

scientific article

Grainyhead-like 3 regulation of endothelin-1 in the pharyngeal endoderm is critical for growth and development of the craniofacial skeleton

scientific article published on 7 June 2014

Growth of intestinal epithelium in organ culture is dependent on EGF signalling

scientific article published in February 2005

Human gingival tissues in culture synthesize three metalloproteinases and a metalloproteinase inhibitor

article

In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation

scientific article published on 25 May 2013

Influence of size, surface, cell line, and kinetic properties on the specific binding of A33 antigen-targeted multilayered particles and capsules to colorectal cancer cells.

scientific article published on September 2007

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

scientific article published on August 2013

Intestinal epithelial exosomes carry MHC class II/peptides able to inform the immune system in mice

scientific article published on December 2003

Macromolecule functionalization of disulfide-bonded polymer hydrogel capsules and cancer cell targeting

scientific article published on 19 January 2012

Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways.

scientific article published in February 2012

Minor class splicing shapes the zebrafish transcriptome during development

scientific article published on 10 February 2014

Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation

scientific article published on 12 November 2007

Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes.

scientific article

Neutrophil-delivered myeloperoxidase dampens the hydrogen peroxide burst after tissue wounding in zebrafish.

scientific article published on 30 August 2012

Osteopetrotic (grey-lethal) bone produces collagenase and TIMP in organ culture: regulation by vitamin A.

scientific article

Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice.

scientific article

Quantitative intratumoural microdistribution and kinetics of (131)I-huA33 antibody in patients with colorectal carcinoma

scientific article

Rabbit cranial suture fibroblasts under tension express a different collagen phenotype

article

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

scientific article published on 9 September 2002

Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

scientific article published on September 2002

Retinoic acid stimulates transcriptional activity from the alkaline phosphatase promoter in the immortalized rat calvarial cell line, RCT-1.

scientific article published on April 1992

SV-40 Large-T Immortalization of Embryonic Bone Cells: Establishment of Osteoblastic Clonal Cell Lines

scientific article published on 01 January 1989

Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation.

scientific article published on 25 June 2008

Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish

scientific article published in March 2006

Suppressor of cytokine signaling-2: a growth hormone-inducible inhibitor of intestinal epithelial cell proliferation

scientific article

T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells

scientific article published on 22 February 2007

TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice.

scientific article published on 25 February 2007

Targeting cancer cells: controlling the binding and internalization of antibody-functionalized capsules

scientific article

Targeting of cancer cells using click-functionalized polymer capsules.

scientific article published on 26 October 2010

The Netrin receptor Neogenin is required for neural tube formation and somitogenesis in zebrafish

scientific article published in May 2004

The drug vehicle and solvent N-methylpyrrolidone is an immunomodulator and antimyeloma compound.

scientific article

The effect of lipopolysaccharide from bacteroides gingivalis and muramyl dipeptide on osteoblast collagenase release

scientific article published on 01 May 1989

The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily

scientific article

The murine A33 antigen is expressed at two distinct sites during development, the ICM of the blastocyst and the intestinal epithelium

scientific journal article

The use of in vitro models for investigating the response of fibrous joints to tensile mechanical stress ⬇️

scientific article published on February 1, 1984

The zebrafish flotte lotte mutant reveals that the local retinal environment promotes the differentiation of proliferating precursors emerging from their stem cell niche

scientific article published on 26 May 2010

Transcriptional networks and signaling pathways that govern vertebrate intestinal development.

scientific article published on January 2010

Uptake and intracellular fate of disulfide-bonded polymer hydrogel capsules for Doxorubicin delivery to colorectal cancer cells.

scientific article

Zebrafish gcm2 is required for gill filament budding from pharyngeal ectoderm

scientific article

c-Myb is required for progenitor cell homeostasis in colonic crypts.

scholarly article

List of works by Joan K. Heath

A factor synthesized by rabbit periosteal fibroblasts stimulates bone resorption and collagenase production by connective tissue cells in vitro

A simple method allowing DIC imaging in conjunction with confocal microscopy.

A33 antigen-deficient mice have defective colonic mucosal repair.

Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish

Anterior mandibular displacement and condylar growth

Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis

Biochemical and autoradiographical evidence that anterior mandibular displacement in the young growing rat does not stimulate cell proliferation or matrix formation at the mandibular condyle

Bypassing multidrug resistance in cancer cells with biodegradable polymer capsules

CREB activity modulates neural cell proliferation, midbrain-hindbrain organization and patterning in zebrafish

Capsosomes with Multilayered Subcompartments: Assembly and Loading with Hydrophobic Cargo

Cellular Association and Cargo Release of Redox-Responsive Polymer Capsules Mediated by Exofacial Thiols

Characterization of posttranslational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium.

Colony-Stimulating Factor-1 Promotes Clonogenic Growth of Normal Murine Colonic Crypt Epithelial Cells In Vitro

Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

Detecting apoptosis during the formation of polarized intestinal epithelium in organ culture

Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms

Dexamethasone regulation of parathyroid hormone-related protein (PTHrP) expression in a squamous cancer cell line.

Efficient gene transfer into the epithelial cell layer of embryonic mouse intestine using low-voltage electroporation.

Electrophoretic analysis of the novel antigen for the gastrointestinal-specific monoclonal antibody, A33.

Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling

Encapsulation of water-insoluble drugs in polymer capsules prepared using mesoporous silica templates for intracellular drug delivery

Evidence for a direct effect of estrogen on bone cells in vitro.

Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis.

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

Grainyhead-like 3 regulation of endothelin-1 in the pharyngeal endoderm is critical for growth and development of the craniofacial skeleton

Growth of intestinal epithelium in organ culture is dependent on EGF signalling

Human gingival tissues in culture synthesize three metalloproteinases and a metalloproteinase inhibitor

In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation

Influence of size, surface, cell line, and kinetic properties on the specific binding of A33 antigen-targeted multilayered particles and capsules to colorectal cancer cells.

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

Intestinal epithelial exosomes carry MHC class II/peptides able to inform the immune system in mice

Macromolecule functionalization of disulfide-bonded polymer hydrogel capsules and cancer cell targeting

Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways.

Minor class splicing shapes the zebrafish transcriptome during development

Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation

Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes.

Neutrophil-delivered myeloperoxidase dampens the hydrogen peroxide burst after tissue wounding in zebrafish.

Osteopetrotic (grey-lethal) bone produces collagenase and TIMP in organ culture: regulation by vitamin A.

Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice.

Quantitative intratumoural microdistribution and kinetics of (131)I-huA33 antibody in patients with colorectal carcinoma

Rabbit cranial suture fibroblasts under tension express a different collagen phenotype

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

Retinoic acid stimulates transcriptional activity from the alkaline phosphatase promoter in the immortalized rat calvarial cell line, RCT-1.

SV-40 Large-T Immortalization of Embryonic Bone Cells: Establishment of Osteoblastic Clonal Cell Lines

Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation.

Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish

Suppressor of cytokine signaling-2: a growth hormone-inducible inhibitor of intestinal epithelial cell proliferation

T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells

TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice.

Targeting cancer cells: controlling the binding and internalization of antibody-functionalized capsules

Targeting of cancer cells using click-functionalized polymer capsules.

The Netrin receptor Neogenin is required for neural tube formation and somitogenesis in zebrafish

The drug vehicle and solvent N-methylpyrrolidone is an immunomodulator and antimyeloma compound.

The effect of lipopolysaccharide from bacteroides gingivalis and muramyl dipeptide on osteoblast collagenase release

The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily

The murine A33 antigen is expressed at two distinct sites during development, the ICM of the blastocyst and the intestinal epithelium

The use of in vitro models for investigating the response of fibrous joints to tensile mechanical stress ⬇️

The zebrafish flotte lotte mutant reveals that the local retinal environment promotes the differentiation of proliferating precursors emerging from their stem cell niche

Transcriptional networks and signaling pathways that govern vertebrate intestinal development.

Uptake and intracellular fate of disulfide-bonded polymer hydrogel capsules for Doxorubicin delivery to colorectal cancer cells.

Zebrafish gcm2 is required for gill filament budding from pharyngeal ectoderm

c-Myb is required for progenitor cell homeostasis in colonic crypts.