List of works by Wolfgang Graier

11,12-Epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells

scientific article published in April 1998

2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.

scientific article published on 5 January 2018

2-chlorohexadecanal derived from hypochlorite-modified high-density lipoprotein-associated plasmalogen is a natural inhibitor of endothelial nitric oxide biosynthesis.

scientific article

A new type of non-Ca2+-buffering Apo(a)-based fluorescent indicator for intraluminal Ca2+ in the endoplasmic reticulum

scientific article published on 20 December 2005

ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes

scientific article published on 01 August 2019

ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release

scientific article published on 04 December 2013

Activation of a small-conductance Ca(2+)-dependent K+ channel contributes to bradykinin-induced stimulation of nitric oxide synthesis in pig aortic endothelial cells

scientific article published on 01 October 1992

Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formation

scientific article published on 6 February 2010

Activation of microsomal cytochrome P450 mono-oxygenase by Ca2+ store depletion and its contribution to Ca2+ entry in porcine aortic endothelial cells

scientific article published on August 1997

Activation of soluble guanylate cyclase by nitrovasodilators is inhibited by oxidized low-density lipoprotein

scientific article published on 01 October 1990

Active autophagy but not lipophagy in macrophages with defective lipolysis.

scientific article

Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production

scientific article

Acyl chain-dependent effect of lysophosphatidylcholine on endothelium-dependent vasorelaxation

scientific article

Adaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells

scientific article

Alterations in platelet Ca2+ signalling in diabetic patients is due to increased formation of superoxide anions and reduced nitric oxide production

scientific article

Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells

scientific article published on 24 November 2003

Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells

scientific article published on April 1999

Annonacin promotes selective cancer cell death via NKA-dependent and SERCA-dependent pathways.

scientific article published on 9 July 2018

Antioxidants prevent high-D-glucose-enhanced endothelial Ca2+/cGMP response by scavenging superoxide anions

scientific article published on 01 March 1997

Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells

scientific article published on 16 March 2017

Assessment of mitochondrial Ca²⁺ uptake

scientific article published in January 2015

Big conductance calcium-activated potassium channel openers control spasticity without sedation.

scientific article published on 5 July 2017

Bradykinin-induced Ca(2+)-influx into cultured aortic endothelial cells is not regulated by inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate

scientific article published on January 1991

C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.

scientific article published on 15 March 2012

Calcium Signaling in ß-cell Physiology and Pathology: A Revisit ⬇️

scientific article published on 04 December 2019

Characterization of distinct single-channel properties of Ca²⁺ inward currents in mitochondria

scientific article published on 9 February 2013

Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.

scientific article

Cholesterol- and caveolin-rich membrane domains are essential for phospholipase A2-dependent EDHF formation

scientific article

Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels

scientific article published on September 2000

Contribution of agonist-induced hyperpolarization to Ca2+ influx and formation of EDRF in vascular endothelial cells

scientific article published on 01 January 1992

Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis

scientific article published on 22 December 2016

Cyclic AMP enhances agonist-induced Ca2+ entry into endothelial cells by activation of potassium channels and membrane hyperpolarization

scientific article published on April 1993

Cytochrome P450 mono-oxygenase-regulated signalling of Ca2+ entry in human and bovine endothelial cells

scientific article published on January 1995

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

scientific article published on 16 August 2018

Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload

scientific article

Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.

scientific article

Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics

scientific article

Diabetic LDL triggers apoptosis in vascular endothelial cells

scientific article published on May 2003

Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity.

scientific article

Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria

scientific article published on 13 October 2017

EDRF-formation increases cGMP-levels in cultured endothelial cells

scientific article published on 01 January 1990

ER-to-Golgi Transport in HeLa Cells Displays High Resilience to Ca2+ and Energy Stresses

scientific article published on 17 October 2020

Effect of intracellular Ca2+ concentration on endothelin-1 secretion

scientific article

Effect of sodium fluoride on cytosolic free Ca2(+)-concentrations and cGMP-levels in endothelial cells

scientific article published on January 1990

Effects of low-dose L-arginine on insulin-mediated vasodilatation and insulin sensitivity

scientific article published on 01 August 1997

Effects of superoxide anions on endothelial Ca2+ signaling pathways

scientific article published on 01 September 1998

Elevation of D-glucose impairs coronary artery autoregulation after slight reduction of coronary flow

scientific article published on 01 August 1995

Endothelial H2O2: a bad guy turning good?

scientific article published on October 2008

Endothelial dysfunction in hypertension

scientific article published on 01 August 1994

Endothelial lipase increases eNOS activating capacity of high-density lipoprotein

scientific article published on 07 January 2020

Endothelial mitochondria--less respiration, more integration

scientific article

Enhanced Ca2+Entry and Tyrosine Phosphorylation Mediate Nanostructure-Induced Endothelial Proliferation.

scientific article

Enhanced inter-compartmental Ca flux modulates mitochondrial metabolism and apoptotic threshold during aging

scientific article published on 09 November 2018

Escherichia coli endotoxin inhibits agonist-mediated cytosolic Ca2+ mobilization and nitric oxide biosynthesis in cultured endothelial cells.

scientific article

Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2) store depletion in endothelial cells

scientific article published on 04 June 2007

Exposure to elevated D-glucose concentrations modulates vascular endothelial cell vasodilatory response.

scientific article

Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo

scientific article published in June 2016

Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.

scientific article published on 27 September 2016

Free fatty acid overload attenuates Ca2+ signaling and NO production in endothelial cells

scientific article published on April 2003

Functional analysis of histamine receptor subtypes involved in endothelium-mediated relaxation of the human uterine artery

scientific article published in August 2002

GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells.

scientific article published on September 2010

Genetic biosensors for imaging nitric oxide in single cells

scientific article published in February 2018

Glycated low-density lipoprotein and atherogenesis: the missing link between diabetes mellitus and hypercholesterolaemia?

scientific article published on 01 June 1997

Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in endothelial cells

scientific article published on 01 June 1999

Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells

scientific article published on 18 February 2019

HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction

scientific article published on 01 January 2020

Heterogeneity of caffeine- and bradykinin-sensitive Ca2+ stores in vascular endothelial cells

scientific article published on June 1994

High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.

scientific article

High-Resolution Imaging of STIM/Orai Subcellular Localization Using Array Confocal Laser Scanning Microscopy

scientific article published on 01 January 2018

High-density lipoprotein antagonizes the inhibitory effects of oxidized low-density lipoprotein and lysolecithin on soluble guanylyl cyclase

scientific article published on January 1992

Histamine induces K+, Ca2+, and Cl- currents in human vascular endothelial cells. Role of ionic currents in stimulation of nitric oxide biosynthesis.

scientific article

Histamine-induced Ca2+ oscillations in a human endothelial cell line depend on transmembrane ion flux, ryanodine receptors and endoplasmic reticulum Ca2+-ATPase

scientific article

Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution

scientific article published on 01 June 1999

Hydrogen peroxide activates Na(+)-dependent Ca(2+) influx in coronary endothelial cells

scientific article

Hyperglycemic conditions affect shape and Ca2+ homeostasis of mitochondria in endothelial cells

scientific article published on October 2004

Hyperkalemia alters EDHF-mediated hyperpolarization and relaxation in coronary arteries

scientific article published on 01 August 1996

IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake

scientific article published on 7 May 2014

IRE1α modulates ER and mitochondria crosstalk

scientific article published on 01 June 2019

Impact of apolipoprotein(a) on in vitro angiogenesis

scientific article published on 01 March 2001

In human hypercholesterolemia increased reactivity of vascular smooth muscle cells is due to altered subcellular Ca(2+) distribution

scientific article published on 01 March 2000

Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF).

scientific article published on December 1992

Inhibition of autophagy rescues palmitic acid-induced necroptosis of endothelial cells

scientific article published on 3 May 2012

Insulin resistance and membrane abnormalities

scholarly article by H Toplak et al published 1 April 1995 in The Lancet

Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).

scientific article published on 03 December 2016

Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression

scientific article

Intracellular Ca2+ release decelerates mitochondrial cristae dynamics within the junctions to the endoplasmic reticulum.

scientific article published on 12 March 2018

Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures

scientific article published on September 2000

Intracellular mechanism of high D-glucose-induced modulation of vascular cell proliferation

scientific article published on 01 December 1995

Intracellular mechanisms involved in D-glucose-mediated amplification of agonist-induced Ca2+ response and EDRF formation in vascular endothelial cells

scientific article published on 01 August 1994

Involvement of the L-arginine-nitric oxide pathway in hyperglycaemia-induced coronary artery dysfunction of isolated guinea pig hearts

scientific article published in August 1996

Is the bradykinin-induced Ca2+ influx and the formation of endothelium-derived relaxing factor mediated by a G protein?

scientific article published on 01 January 1992

Lipid-independent control of endothelial and neuronal TRPC3 channels by light

scientific article published on 15 January 2019

Lipoprotein lipase mediates the uptake of glycated LDL in fibroblasts, endothelial cells, and macrophages

scientific article

Live cell imaging of signaling and metabolic activities

scientific article published on 07 June 2019

Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes.

scientific article

Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture

scientific article

Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.

scientific article published on 19 December 2017

Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice

scientific article published on 06 May 2016

Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.

scientific article published on 24 January 2018

MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex

scientific article published on 19 August 2019

Mechanisms of Ca2+ store depletion in single endothelial cells in a Ca(2+)-free environment

scientific article published on 01 May 1999

Mechanisms of L-NG nitroarginine/indomethacin-resistant relaxation in bovine and porcine coronary arteries

scientific article published in November 1996

Metabolism-secretion coupling and mitochondrial calcium activities in clonal pancreatic β-cells

scientific article published on January 2014

Mg2+ deprivation elicits rapid Ca2+ uptake and activates Ca2+/calcineurin signaling in Saccharomyces cerevisiae

scientific article published on 2 March 2007

MiR-206 is expressed in pancreatic islets and regulates glucokinase activity

scientific article published on 24 May 2016

Mitochondria efficiently buffer subplasmalemmal Ca2+ elevation during agonist stimulation

scientific article published on 15 January 2003

Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum

scientific article published on May 2006

Mitochondrial Ca(2+) uniporter (MCU)-dependent and MCU-independent Ca(2+) channels coexist in the inner mitochondrial membrane

scientific article published on 27 October 2013

Mitochondrial Ca2+ channels: Great unknowns with important functions.

scientific article published on 15 January 2010

Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial Ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells.

scientific article published in December 2012

Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells

scientific article published on 17 August 2012

Mitochondrial Ca2+ uptake and not mitochondrial motility is required for STIM1-Orai1-dependent store-operated Ca2+ entry

scientific article published on 29 June 2010

Mitochondrial-Endoplasmic Reticulum Interplay: A Lifelong On-Off Relationship?

scientific article published on 19 July 2019

Molecularly distinct routes of mitochondrial Ca2+ uptake are activated depending on the activity of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA)

scientific article published on 16 April 2013

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice

scientific article

Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro

scientific article published on 09 February 2020

N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs.

scientific article published on June 2013

N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health

scientific article published on 01 November 2019

N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes

scientific article published on 5 April 2016

N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.

scientific article published on 31 August 2018

NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes

scientific article published on 23 October 2013

Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling

scientific article published on November 2002

Nonclassical nuclear localization signals mediate nuclear import of CIRBP

scientific article published on 31 March 2020

Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo

scientific article published on 10 November 2017

Oleoyl-lysophosphatidylcholine limits endothelial nitric oxide bioavailability by induction of reactive oxygen species

scientific article (publication date: 2014)

Origin and function of epoxyeicosatrienoic acids in vascular endothelial cells: more than just endothelium-derived hyperpolarizing factor?

scientific article published on October 1998

Oxidized low-density lipoprotein antagonizes the activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor but does not interfere with its biosynthesis

scientific article published on 01 January 1991

Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.

scientific article published in January 2002

PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells

scientific article

Pharmacologic differentiation between endothelium-dependent relaxations sensitive and resistant to nitro-L-arginine in coronary arteries

scientific article published on 01 May 1994

Presenilin-1 Established ER-Ca2+ Leak: a Follow Up on Its Importance for the Initial Insulin Secretion in Pancreatic Islets and β-Cells upon Elevated Glucose

scientific article published on 01 January 2019

Publisher Correction: IRE1α modulates ER and mitochondria crosstalk

scientific article published on 01 October 2019

Purification and Application of Genetically Encoded Potassium Ion Indicators for Quantification of Potassium Ion Concentrations within Biological Samples

scientific article published on 01 September 2019

RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure

scientific article published on 07 August 2018

Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells

article

Real-Time Imaging of Nitric Oxide Signals in Individual Cells Using geNOps.

scientific article published in January 2018

Real-time visualization of distinct nitric oxide generation of nitric oxide synthase isoforms in single cells

scientific article

Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2.).

scientific article published on 22 October 2015

Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria

scientific article published on 9 September 2016

Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia

scientific article published on 01 December 1997

SK&F 96365 inhibits histamine-induced formation of endothelium-derived relaxing factor in human endothelial cells

scientific article published on 01 August 1992

Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide

scientific article published on 01 January 1999

Spatiotemporal correlations between cytosolic and mitochondrial Ca(2+) signals using a novel red-shifted mitochondrial targeted cameleon

scientific article

Stealth ryanodine-sensitive Ca2+ release contributes to activity of capacitative Ca2+ entry and nitric oxide synthase in bovine endothelial cells

scientific article published on 01 December 1998

Studying mitochondrial Ca(2+) uptake - a revisit.

scientific article published on 11 November 2011

Submaximal stimulation of porcine endothelial cells causes focal Ca2+ elevation beneath the cell membrane.

scientific article

Subplasmalemmal endoplasmic reticulum controls K(Ca) channel activity upon stimulation with a moderate histamine concentration in a human umbilical vein endothelial cell line

scientific article published on April 2002

Subplasmalemmal ryanodine-sensitive Ca2+ release contributes to Ca2+-dependent K+ channel activation in a human umbilical vein endothelial cell line

scientific article

Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, sore-operated Ca2+ entry, and Ca2+ store refilling

scientific article published on 26 August 2003

Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle Without Added Reductants. Implications for the Development of Nitrate Tolerance

scientific article published on 22 January 2018

T-cadherin mediates low-density lipoprotein-initiated cell proliferation via the Ca(2+)-tyrosine kinase-Erk1/2 pathway

scientific article

TRPV1 mediates cellular uptake of anandamide and thus promotes endothelial cell proliferation and network-formation

scientific article

Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction.

scientific article published on 16 March 2018

Targeting cellular senescence based on inter-organelle communication, multi-level proteostasis and metabolic control

scientific article published on 17 November 2020

Temperature dependence of agonist-stimulated Ca2+ signaling in cultured endothelial cells.

scientific article published in January 1997

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

scientific article published in Journal of Biological Chemistry

The GPR 55 agonist, L-α-lysophosphatidylinositol, mediates ovarian carcinoma cell-induced angiogenesis

scientific article

The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K+ channels in endothelial cells.

scientific article published on 12 November 2010

The Role of Mitochondria in the Activation/Maintenance of SOCE: The Contribution of Mitochondrial Ca2+ Uptake, Mitochondrial Motility, and Location to Store-Operated Ca2+ Entry

scientific article published on January 2017

The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk

scientific article published on 11 August 2017

The contribution of UCP2 and UCP3 to mitochondrial Ca(2+) uptake is differentially determined by the source of supplied Ca(2+)

scientific article published on 18 April 2010

The effects of intracellular Ca2+ concentration and hypoxia on basal endothelin-1 secretion by cultured porcine aortic endothelial cells.

scientific article published on January 1995

The endocannabinoid N-arachidonoyl glycine (NAGly) inhibits store-operated Ca2+ entry by preventing STIM1-Orai1 interaction

scientific article published on 13 December 2012

The enigmatic ATP supply of the endoplasmic reticulum

scientific article

The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum

scientific article published on 19 January 2005

The vascular barrier-protecting hawthorn extract WS® 1442 raises endothelial calcium levels by inhibition of SERCA and activation of the IP3 pathway

scientific article

Time course of endothelial dysfunction in diabetes mellitus.

scientific article

Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice

scientific article

Tracking intra- and inter-organelle signaling of mitochondria

scientific article published on 11 November 2019

Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages

scientific article

Twenty years of calcium imaging: cell physiology to dye for.

scientific article

UCP2 and PRMT1 are key prognostic markers for lung carcinoma patients

scientific article published on 28 August 2017

UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria

scientific article published on 16 August 2015

Uncoupling protein 3 adjusts mitochondrial Ca(2+) uptake to high and low Ca(2+) signals

scientific article published on 2 November 2010

Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport

scientific article

Vascular effects of L-arginine: anything beyond a substrate for the NO-synthase?

scientific article published on 01 May 1997

Vesicular calcium regulates coat retention, fusogenicity, and size of pre-Golgi intermediates.

scientific article

Visualization of Sirtuin 4 Distribution between Mitochondria and the Nucleus, Based on Bimolecular Fluorescence Self-Complementation

scientific article published on 06 December 2019

Yes (again) to local NO

scientific article published on 01 June 2020

miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages

scientific article

pH-Lemon, a Fluorescent Protein-Based pH Reporter for Acidic Compartments

scientific article published on 30 March 2019

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