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List of works by Roland Malli

2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.

scientific article published on 5 January 2018

A new type of non-Ca2+-buffering Apo(a)-based fluorescent indicator for intraluminal Ca2+ in the endoplasmic reticulum

scientific article published on 20 December 2005

ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release

scientific article published on 04 December 2013

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

article

Acyl chain-dependent effect of lysophosphatidylcholine on cyclooxygenase (COX)-2 expression in endothelial cells ⬇️

scientific article published on August 2, 2012

Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production

scientific article

Adaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells

scientific article

Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function

scientific article published on 16 March 2020

Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells

scientific article published on 24 November 2003

Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells

scientific article published on 16 March 2017

Assessment of mitochondrial Ca²⁺ uptake

scientific article published in January 2015

C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.

scientific article published on 15 March 2012

Ca2+ refilling of the endoplasmic reticulum is largely preserved albeit reduced Ca2+ entry in endothelial cells

scientific article

Calcium Signaling in ß-cell Physiology and Pathology: A Revisit ⬇️

scientific article published on 04 December 2019

Characterization of distinct single-channel properties of Ca²⁺ inward currents in mitochondria

scientific article published on 9 February 2013

Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.

scientific article

Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload

scientific article

Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics

scientific article

Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca2+-dependent induction of oxidative stress ⬇️

scientific article published on March 3, 2012

ER-to-Golgi Transport in HeLa Cells Displays High Resilience to Ca2+ and Energy Stresses

scientific article published on 17 October 2020

Endothelial mitochondria—less respiration, more integration ⬇️

scientific article published on March 1, 2012

Enhanced inter-compartmental Ca flux modulates mitochondrial metabolism and apoptotic threshold during aging

scientific article published on 09 November 2018

Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2) store depletion in endothelial cells

scientific article published on 04 June 2007

Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism

scientific article published on 21 January 2022

Fatty acids as biomimetic replication agents for luminescent metal-organic framework patterns

scientific article published on 23 September 2020

Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo

scientific article published in June 2016

Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.

scientific article published on 27 September 2016

Functional analysis of histamine receptor subtypes involved in endothelium-mediated relaxation of the human uterine artery

scientific article published in August 2002

GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells.

scientific article published on September 2010

Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum.

scientific article published on 4 June 2015

Genetic biosensors for imaging nitric oxide in single cells

scientific article published in February 2018

Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells

scientific article published on 18 February 2019

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome

scientific article

High-Resolution Imaging of STIM/Orai Subcellular Localization Using Array Confocal Laser Scanning Microscopy

scientific article published on 01 January 2018

Hyperglycemic conditions affect shape and Ca2+ homeostasis of mitochondria in endothelial cells

scientific article published on October 2004

IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake

scientific article published on 7 May 2014

Inhibition of autophagy rescues palmitic acid-induced necroptosis of endothelial cells

scientific article published on 3 May 2012

Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).

scientific article published on 03 December 2016

Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression

scientific article

Intracellular Ca2+ release decelerates mitochondrial cristae dynamics within the junctions to the endoplasmic reticulum

scientific article published on 12 March 2018

Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts

scientific article

Leucine zipper EF hand-containing transmembrane protein 1 (Letm1) and uncoupling proteins 2 and 3 (UCP2/3) contribute to two distinct mitochondrial Ca2+ uptake pathways ⬇️

scientific article

Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes.

scientific article

Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture

scientific article

MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex

scientific article published on 19 August 2019

Mg2+ deprivation elicits rapid Ca2+ uptake and activates Ca2+/calcineurin signaling in Saccharomyces cerevisiae

scientific article published on 2 March 2007

Mitochondria efficiently buffer subplasmalemmal Ca2+ elevation during agonist stimulation

scientific article published on 15 January 2003

Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum

scientific article published on May 2006

Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca

scientific article published on 09 September 2019

Mitochondrial Ca(2+) uniporter (MCU)-dependent and MCU-independent Ca(2+) channels coexist in the inner mitochondrial membrane

scientific article published on 27 October 2013

Mitochondrial Ca2+ channels: Great unknowns with important functions.

scientific article published on 15 January 2010

Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial Ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells.

scientific article published in December 2012

Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells

scientific article published on 17 August 2012

Mitochondrial Ca2+ uptake and not mitochondrial motility is required for STIM1-Orai1-dependent store-operated Ca2+ entry

scientific article published on 29 June 2010

Mitochondrial Ca2+, the secret behind the function of uncoupling proteins 2 and 3?

scientific article published on 20 February 2008

Mitochondrial protein phosphorylation: instigator or target of lipotoxicity?

scientific article published on 07 April 2009

Molecularly distinct routes of mitochondrial Ca2+ uptake are activated depending on the activity of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA)

scientific article published on 16 April 2013

Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability

scientific article

N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs.

scientific article published on June 2013

Na +/Ca2+ exchangers and Orai channels jointly refill endoplasmic reticulum (ER) Ca2+ via ER nanojunctions in vascular endothelial cells

scientific article published on 11 May 2017

Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling

scientific article published on November 2002

Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo

scientific article published on 10 November 2017

Novel high energy intermediate analogues with triazasterol-related structures as inhibitors of ergosterol biosynthesis. Part I: synthesis and antifungal activity of N-alkyl-N'-(phenethyl- and cyclohexenylethyl)guanidines and N2-substituted 2-imidazo

scientific article published in January 2002

Oleoyl-lysophosphatidylcholine limits endothelial nitric oxide bioavailability by induction of reactive oxygen species

scientific article (publication date: 2014)

Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.

scientific article published in January 2002

PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells

scientific article

Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells

article

Real-Time Imaging of Nitric Oxide Signals in Individual Cells Using geNOps

scientific article published in January 2018

Real-time visualization of distinct nitric oxide generation of nitric oxide synthase isoforms in single cells

scientific article

Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2.).

scientific article published on 22 October 2015

Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria

scientific article published on 9 September 2016

Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo

scientific article

Spatiotemporal correlations between cytosolic and mitochondrial Ca(2+) signals using a novel red-shifted mitochondrial targeted cameleon

scientific article

Studying mitochondrial Ca(2+) uptake - a revisit.

scientific article published on 11 November 2011

Subplasmalemmal endoplasmic reticulum controls K(Ca) channel activity upon stimulation with a moderate histamine concentration in a human umbilical vein endothelial cell line

scientific article published on April 2002

Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, sore-operated Ca2+ entry, and Ca2+ store refilling

scientific article published on 26 August 2003

Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle Without Added Reductants. Implications for the Development of Nitrate Tolerance

scientific article published on 22 January 2018

TRIC-A shapes oscillatory Ca2+ signals by interaction with STIM1/Orai1 complexes

scientific article published on 24 April 2020

TRPV1 mediates cellular uptake of anandamide and thus promotes endothelial cell proliferation and network-formation

scientific article

Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction

scientific article published on 16 March 2018

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

scientific article published in Journal of Biological Chemistry

The ER chaperone calnexin controls mitochondrial positioning and respiration

scientific article published on 30 June 2020

The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K+ channels in endothelial cells.

scientific article published on 12 November 2010

The Role of Mitochondria in the Activation/Maintenance of SOCE: The Contribution of Mitochondrial Ca2+ Uptake, Mitochondrial Motility, and Location to Store-Operated Ca2+ Entry

scientific article published on January 2017

The contribution of UCP2 and UCP3 to mitochondrial Ca(2+) uptake is differentially determined by the source of supplied Ca(2+)

scientific article published on 18 April 2010

The endocannabinoid N-arachidonoyl glycine (NAGly) inhibits store-operated Ca2+ entry by preventing STIM1-Orai1 interaction

scientific article published on 13 December 2012

The enigmatic ATP supply of the endoplasmic reticulum

scientific article

The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum

scientific article published on 19 January 2005

The vascular barrier-protecting hawthorn extract WS® 1442 raises endothelial calcium levels by inhibition of SERCA and activation of the IP3 pathway

scientific article

Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice

scientific article

Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages

scientific article

Twenty years of calcium imaging: cell physiology to dye for.

scientific article

UCP2 and PRMT1 are key prognostic markers for lung carcinoma patients

scientific article published on 28 August 2017

UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria

scientific article published on 16 August 2015

Uncoupling protein 3 adjusts mitochondrial Ca(2+) uptake to high and low Ca(2+) signals

scientific article published on 2 November 2010

Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport

scientific article

Vesicular calcium regulates coat retention, fusogenicity, and size of pre-Golgi intermediates.

scientific article

Visualization of Sirtuin 4 Distribution between Mitochondria and the Nucleus, Based on Bimolecular Fluorescence Self-Complementation

scientific article published on 06 December 2019

Yes (again) to local NO

scientific article published on 01 June 2020

pH-Lemon, a Fluorescent Protein-Based pH Reporter for Acidic Compartments

scientific article published on 30 March 2019

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