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List of works by Hellmut G Augustin

A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis.

scientific article published on December 2009

A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain

scientific article

A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain.

scientific article published in August 2015

A Synopsis of the "Influence of Epigenetics, Genetics, and Immunology" Session Part A at the 35th Annual Society of Toxicologic Pathology Symposium

scientific article published on 5 October 2016

Activated protein C resistance and Factor V Leiden in patients with hemolysis, elevated liver enzymes, low platelets syndrome

scientific article published on 01 September 1998

Amelioration of sepsis by TIE2 activation-induced vascular protection.

scientific article

An inducible hepatocellular carcinoma model for preclinical evaluation of antiangiogenic therapy in adult mice.

scientific article published on 6 June 2014

Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis

scientific article published in November 1998

Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy

scientific article published on 4 October 2013

Angiogenesis in the female reproductive system

scientific article published on 01 January 2005

Angiogenesis research--quo vadis?

scientific article published in February 2003

Angiogenesis: molecular mechanisms and functional interactions--2nd Kloster Seeon Meeting of the German Priority Research Grant "Angiogenesis"

article

Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis

scientific article

Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions

scientific article

Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin-2 from endothelial cells

scientific article published on 14 April 2012

Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

scientific article

Angiopoietin-2 is critical for cytokine-induced vascular leakage

scientific article

Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma

scientific article published in February 2009

Angiopoietin-2 mediates thrombin-induced monocyte adhesion and endothelial permeability

scientific article published on 31 May 2016

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

scientific article published on 5 February 2006

Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation

scientific article

Angiopoietin-2: an attractive target for improved antiangiogenic tumor therapy

scientific article published on 06 March 2013

Angiopoietins: a link between angiogenesis and inflammation.

scientific article published on 12 October 2006

Antiangiogenic tumour therapy: will it work? ⬇️

scientific article published on June 1, 1998

BMP-9 Modulates the Hepatic Responses to LPS

scientific article published on 04 March 2020

BMP-9 interferes with liver regeneration and promotes liver fibrosis.

scientific article published on 23 March 2017

BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis

scientific article

Basic fibroblast growth factor (bFGF) regulates the expression of the CC chemokine monocyte chemoattractant protein-1 (MCP-1) in autocrine-activated endothelial cells

scientific article published on November 1997

Beyond Angiogenesis: Exploiting Angiocrine Factors to Restrict Tumor Progression and Metastasis

scientific article published on 12 December 2019

Bi-directional cell contact-dependent regulation of gene expression between endothelial cells and osteoblasts in a three-dimensional spheroidal coculture model

article

Biochemical and metabolic properties of bovine type II pneumocytes in primary culture

scientific article

Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness

scientific article published in February 2001

Born to Die – Blood Vessel Regression Research Coming of Age

2012 scholarly article

Cancer: Blood vessels kept quiet

scientific article published in March 2009

Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice

scientific article published on 02 May 2022

Circulating endothelial cell adhesion molecules as diagnostic markers for the early identification of pregnant women at risk for development of preeclampsia

scientific article

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

scientific article

Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.

scientific article published on April 2009

Commentary on Folkman: "How Is Blood Vessel Growth Regulated in Normal and Neoplastic Tissue?".

scientific article published in May 2016

Comparison of growth and differentiation of normal and neoplastic canine keratinocyte cultures

scientific article

Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

scientific article published on March 2009

Cyclic angiogenesis and blood vessel regression in the ovary: blood vessel regression during luteolysis involves endothelial cell detachment and vessel occlusion.

scientific article published in April 1996

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia

scientific article

Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression

scientific article published on 09 May 2016

Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin

scientific article

Differentiation of endothelial cells: analysis of the constitutive and activated endothelial cell phenotypes

scientific article published on December 1994

Differentiation-dependent expression of lectin binding sites on normal and neoplastic keratinocytes in vivo and in vitro

scientific article published on August 1991

Dissociation of angiogenesis and tumorigenesis in follistatin- and activin-expressing tumors

scientific article published on June 2006

Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation

scientific article published on 12 March 2009

Double Attack on Tumors by Targeting With Guidance Molecules

scientific article published on 01 April 2011

Down-Regulation of Endothelial EphrinB2 Expression by Laminar Shear Stress

scientific article published on 01 September 2004

Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression

scientific article published on 23 May 2016

Emerging roles of the Angiopoietin-Tie and the ephrin-Eph systems as regulators of cell trafficking.

scientific article published on 24 July 2006

Endosialin (Tem1) is a marker of tumor-associated myofibroblasts and tumor vessel-associated mural cells

scientific article published on 10 January 2008

Endosialin Promotes Atherosclerosis Through Phenotypic Remodeling of Vascular Smooth Muscle Cells

scientific article published on 26 January 2017

Endosialin-Expressing Pericytes Promote Metastatic Dissemination.

scientific article

Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat

scientific article published in Science

Endothelial EphrinB2 Is Controlled by Microenvironmental Determinants and Associates Context-Dependently With CD31

scientific article published on 15 December 2005

Endothelial cell fitness dictates the source of regenerating liver vasculature

scientific article published on 07 September 2018

Endothelial cell membrane vesicles in the study of organ preference of metastasis

scientific article published on January 1991

Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro

scientific article published on 9 April 2015

Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/fusin) under the control of autocrine activity and exogenous cytokines

scientific article published in June 1998

Endothelial transcription factor KLF2 negatively regulates liver regeneration via induction of activin A

scientific article

Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin-2 expression in peri-tumourous liver correlates with increased survival.

scientific article published on 21 July 2013

Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression

scientific article

EphB receptors and ephrinB ligands: regulators of vascular assembly and homeostasis

scientific article

EphB4 promotes site-specific metastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinB2.

scientific article published on 13 September 2010

Ephrin-B2 expression critically influences Nipah virus infection independent of its cytoplasmic tail

scientific article published on 24 December 2008

Expression of angiopoietin-2 in endothelial cells is controlled by positive and negative regulatory promoter elements

scientific article published on 29 July 2004

Extracellular RNA liberates tumor necrosis factor-α to promote tumor cell trafficking and progression

scientific article published on 17 June 2013

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

scientific article

Fetal plasma levels of circulating endothelial cell adhesion molecules in normal and preeclamptic pregnancies

scientific article published in May 1998

Flow-dependent regulation of angiopoietin-2.

scientific article published in February 2008

Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells

scientific article

Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.

scientific article published on 13 July 2009

G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency.

scientific article

GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis

scientific article

Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage

scientific article

Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin.

scientific article

Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies.

scientific article published in March 2000

Histone deacetylase 9 promotes angiogenesis by targeting the antiangiogenic microRNA-17-92 cluster in endothelial cells

scientific article published on 3 January 2013

Host-derived angiopoietin-2 affects early stages of tumor development and vessel maturation but is dispensable for later stages of tumor growth

scientific article

Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma.

scientific article

Implications of vascular endothelial growth factor, sFlt-1, and sTie-2 in plasma, serum and cerebrospinal fluid during cerebral ischemia in man.

scientific article

Induction of inflammatory angiogenesis by monocyte chemoattractant protein-1

scientific article published on 01 August 1999

Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis

scientific article

Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation

scientific article published on November 1998

Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis

scientific article

Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function

scientific article published in November 2003

Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes

scientific article published on 28 October 2008

Isolation of bovine type II pneumocytes in high yield and purity

scientific article

Judah Folkman

scientific article published in February 2008

Junb regulates arterial contraction capacity, cellular contractility, and motility via its target Myl9 in mice

scientific article

Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression

scientific article published in 2022

Mechanisms of Vessel Pruning and Regression.

scientific article published on July 2015

Metastasis: imaging shows the way

MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling.

scientific article

MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of angiopoietin 2.

scientific article

Models in Translational Oncology: A Public Resource Database for Preclinical Cancer Research

scientific article published on May 2017

Modulation of endothelial cell surface glycoconjugate expression by organ-derived biomatrices

scientific article published on 01 February 1991

Modulation of in vitro angiogenesis in a three-dimensional spheroidal coculture model for bone tissue engineering.

scientific article

Mouse models of human cancer

scientific article published on 18 August 2014

Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2

scientific article

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

scientific article published on 24 March 2021

Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor

scientific article published on 21 December 2006

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation

scientific article

Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1.

scientific article published on 15 July 2008

No evidence for a functional role of bi-directional Notch signaling during angiogenesis

scientific article

Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment

scientific article published in December 2016

Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment.

scientific article published in January 2017

Organ-preference of metastasis. The role of endothelial cell adhesion molecules

scientific article

Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology

scientific article published on 3 August 2017

Ovarian angiogenesis. Phenotypic characterization of endothelial cells in a physiological model of blood vessel growth and regression

scientific article published on August 1995

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

scientific article published on 18 July 2017

Phenotypic Characterization of Normal and Neoplastic Canine Endothelial Cells by Lectin Histochemistry

scientific article published on 01 March 1990

Plastic roles of pericytes in the blood-retinal barrier.

scientific article

Postsurgical adjuvant tumor therapy by combining anti-angiopoietin-2 and metronomic chemotherapy limits metastatic growth

scientific article

Potent inhibition of angiogenesis by D,L-peptides derived from vascular endothelial growth factor receptor 2

scientific article published on 01 September 2003

Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody

scientific article published on 17 April 2020

Prognostic value of angiogenesis in mammary tumors

scientific article published on 01 May 1998

Prospective analysis of placenta growth factor (PlGF) concentrations in the plasma of women with normal pregnancy and pregnancies complicated by preeclampsia

scientific article

Quantitative analysis of autocrine-regulated, matrix-induced, and tumor cell-stimulated endothelial cell migration using a silicon template compartmentalization technique

scientific article

Rapid identification of differentially expressed endothelial cell genes by RNA display

scientific article

Recruitment of human cord blood-derived endothelial colony-forming cells to sites of tumor angiogenesis

scientific article

Resistance to antiangiogenic therapy is directed by vascular phenotype, vessel stabilization, and maturation in malignant melanoma

Rhodocetin-αβ-induced neuropilin-1-cMet association triggers restructuring of matrix contacts in endothelial cells.

scientific article

Role of ephrinB2 expression in endothelial cells during arteriogenesis: impact on smooth muscle cell migration and monocyte recruitment

scientific article

Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells.

scientific article

Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesis.

scientific article

Senescence of aortic endothelial cells in culture: Effects of basic fibroblast growth factor expression on cell phenotype, migration, and proliferation

article

Spheroid-based engineering of a human vasculature in mice

scientific article published on 6 April 2008

Spheroid-based human endothelial cell microvessel formation in vivo

scientific article published on 30 July 2009

State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association

scientific article

Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis

scientific article

Tension in the vasculature

scientific article published on 01 June 2009

Tensional forces in fibrillar extracellular matrices control directional capillary sprouting.

scientific article published in October 1999

The BTB-Kelch protein KLEIP controls endothelial migration and sprouting angiogenesis.

scientific article

The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis

scientific journal article

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells.

scientific article published on 2 September 2015

The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism

scientific article

The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies

scientific article published on 19 February 2004

The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development

scientific journal article

The activin-binding protein follistatin regulates autocrine endothelial cell activity and induces angiogenesis

scientific article published in February 1997

The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms.

scientific article published on 29 November 2005

The role of the Angiopoietins in vascular morphogenesis.

scientific article published on 16 May 2009

The transcription factor HOXC9 regulates endothelial cell quiescence and vascular morphogenesis in zebrafish via inhibition of interleukin 8.

scientific article

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.

scientific article

Therapeutic interference with EphrinB2 signalling inhibits oxygen-induced angioproliferative retinopathy

scientific article published on 01 February 2011

Three-dimensional spheroidal culture of cytotrophoblast cells mimics the phenotype and differentiation of cytotrophoblasts from normal and preeclamptic pregnancies

scientific article published in July 2004

Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration ⬇️

scientific article published on 13 February 2019

Timed Ang2-targeted therapy identifies the Angiopoietin-Tie pathway as key regulator of fatal lymphogenous metastasis

scientific article published on 26 October 2020

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.

scientific article

Transcriptional regulation of the Ras-related protein TC21/R-Ras2 in endothelial cells

scientific article published in September 1997

Tubes, branches, and pillars: the many ways of forming a new vasculature

scientific article published on 01 October 2001

Tumor cell-derived Angiopoietin-2 promotes metastasis in melanoma

scientific article published on 17 April 2020

Tumor stroma marker endosialin (Tem1) is a binding partner of metastasis-related protein Mac-2 BP/90K.

scientific article

Understanding angiodiversity: insights from single cell biology

scientific article published on 12 August 2020

Unique cell type-specific junctional complexes in vascular endothelium of human and rat liver sinusoids

scientific article

VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation.

scientific article published on 13 March 2017

VEGFR1+ Metastasis-Associated Macrophages Contribute to Metastatic Angiogenesis and Influence Colorectal Cancer Patient Outcome

scientific article published on 25 June 2019

Vascular morphogenesis in the ovary

scientific article published on 01 December 2000

Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells

scientific article published on 07 June 2021

Wanted: cancer boss

scientific article published in Nature

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