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List of works by Changsheng Zhang

Activation and Characterization of Bohemamine Biosynthetic Gene Cluster from Streptomyces sp. CB02009

scientific article published on 28 May 2020

Activation and characterization of a cryptic gene cluster reveals a cyclization cascade for polycyclic tetramate macrolactams. ⬇️

scientific article published on 28 October 2016

Acyclic Congeners from Actinoalloteichus cyanogriseus Provide Insights into Cyclic Bipyridine Glycoside Formation

scientific article published on 04 August 2014

Albumycin, a new isoindolequinone from Streptomyces albus J1074 harboring the fluostatin biosynthetic gene cluster

scientific article published on 28 February 2019

Antibiotic optimization via in vitro glycorandomization ⬇️

scientific article published on November 9, 2003

Antimalarial β-carboline and indolactam alkaloids from Marinactinospora thermotolerans, a deep sea isolate

scientific article published on 6 October 2011

Biosynthesis of himastatin: assembly line and characterization of three cytochrome P450 enzymes involved in the post-tailoring oxidative steps

scientific article published on 01 July 2011

Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway.

scientific article

Characterization of a Sugar-O-methyltransferase TiaS5 Affords New Tiacumicin Analogues with Improved Antibacterial Properties and Reveals Substrate Promiscuity

article by Siwen Niu et al published 1 June 2011 in ChemBioChem

Characterization of the flavoenzyme XiaK as an N-hydroxylase and implications in indolosesquiterpene diversification.

scientific article published on 4 May 2017

Characterization of the sugar-O-methyltransferase LobS1 in lobophorin biosynthesis

scientific article published on 20 July 2013

Characterizing Two Cytochrome P450s in Tiacumicin Biosynthesis Reveals Reaction Timing for Tailoring Modifications

scientific article published on 11 September 2019

Cylindromicin from Arctic-Derived Fungus Tolypocladium sp. SCSIO 40433 ⬇️

Deciphering Biosynthetic Enzymes Leading to 4-Chloro-6-Methyl-5,7-Dihydroxyphenylglycine, a Non-Proteinogenic Amino Acid in Totopotensamides

scientific article published on 09 March 2020

Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.

scientific article

Discovery and Biosynthesis of Neoenterocins Indicate a Skeleton Rearrangement of Enterocin

scientific article published on 28 October 2019

Discovery of Stealthin Derivatives and Implication of the Amidotransferase FlsN3 in the Biosynthesis of Nitrogen-Containing Fluostatins ⬇️

scientific article published on 04 March 2019

Diversifying vancomycin via chemoenzymatic strategies.

scientific article

Engineered Biosynthesis of 5/5/6 Type Polycyclic Tetramate Macrolactams in an Ikarugamycin (5/6/5 Type)-Producing Chassis

scientific article published on 13 February 2020

Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions

scientific article

Genome Mining and Activation of a Silent PKS/NRPS Gene Cluster Direct the Production of Totopotensamides

scientific article published on 11 October 2017

Genome Mining of Marine-Derived Streptomyces sp. SCSIO 40010 Leads to Cytotoxic New Polycyclic Tetramate Macrolactams ⬇️

scientific article published on 25 November 2019

Heterologous Expression Leads to Discovery of Diversified Lobophorin Analogues and a Flexible Glycosyltransferase

scientific article published on 23 January 2020

Heterologous expression of the trichostatin gene cluster and functional characterization of N-methyltransferase TsnB8

scientific article published on 01 May 2020

Host-dependent heterologous expression of berninamycin gene cluster leads to linear thiopeptide antibiotics

scientific article published in October 2021

Identification and Characterization of Xiamycin A and Oxiamycin Gene Cluster Reveals an Oxidative Cyclization Strategy Tailoring Indolosesquiterpene Biosynthesis ⬇️

scientific article published on May 16, 2012

Identification and bioactivity evaluation of secondary metabolites from Antarctic-derived <i>Penicillium chrysogenum</i> CCTCC M 2020019

scientific article published on 01 May 2020

Identification and characterization of a biosynthetic gene cluster for tryptophan dimers in deep sea-derived Streptomyces sp. SCSIO 03032.

scientific article published on 15 June 2017

Identification of a 1-epi-valienol 7-kinase activity in the producer of acarbose, Actinoplanes sp. SE50/110.

scientific article published in April 2003

Identification of caerulomycin A gene cluster implicates a tailoring amidohydrolase

scientific article published on 16 May 2012

Marine Bacterial Aromatic Polyketides From Host-Dependent Heterologous Expression and Fungal Mode of Cyclization ⬇️

scientific article published on 30 October 2018

Mechanistic insights into polycycle formation by reductive cyclization in ikarugamycin biosynthesis

scientific article published on 6 April 2014

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines.

scientific article

Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine.

scientific article

Nocardiamides A and B, two cyclohexapeptides from the marine-derived actinomycete Nocardiopsis sp. CNX037.

scientific article published on 15 April 2013

Penicacids A–C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07 ⬇️

scientific article published on March 11, 2012

Proximicins F and G and Diproximicin A: Aminofurans from the Marine-Derived Verrucosispora sp. SCSIO 40062 by Overexpression of PPtase Genes

scientific article published on 19 March 2020

Pyrazolofluostatins A-C, Pyrazole-Fused Benzo[a]fluorenes from South China Sea-Derived Micromonospora rosaria SCSIO N160.

scientific article published on 11 January 2017

Recent Advances in Discovery, Biosynthesis and Genome Mining of Medicinally Relevant Polycyclic Tetramate Macrolactams

scientific article published on 12 October 2015

Recombinant E. coli prototype strains for in vivo glycorandomization.

scientific article

Refactoring the Concise Biosynthetic Pathway of Cyanogramide Unveils a P450 Enzyme-catalyzed Spirooxindole Formation

scientific article published on 23 April 2020

S-Bridged Thioether and Structure-Diversified Angucyclinone Derivatives from the South China Sea-Derived Micromonospora echinospora SCSIO 04089

scientific article published on 24 September 2020

Structural studies reveal flexible roof of active site responsible for ω-transaminase CrmG overcoming by-product inhibition

scientific article published on 19 August 2020

Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM

scientific article

The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a 2-epi-5-epi-valiolone-7-phosphate 2-epimerase

scientific article published in April 2003

The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility

scientific article

Tiacumicin Congeners with Improved Antibacterial Activity from a Halogenase-Inactivated Mutant.

scientific article published on 20 April 2018

Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis

scientific article published on 26 May 2020

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