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List of works by Markus Glatzel

3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3.

scientific article published on 14 March 2007

A case-control study of sporadic Creutzfeldt-Jakob disease in Switzerland: analysis of potential risk factors with regard to an increased CJD incidence in the years 2001-2004.

scientific article published on 14 January 2009

A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's disease

scientific article published on 14 December 2020

A novel interaction between aging and ER overload in a protein conformational dementia

scientific article published on 18 January 2013

A novel single-chain antibody fragment for detection of mannose 6-phosphate-containing proteins: application in mucolipidosis type II patients and mice

scientific article published on 14 May 2010

Accumulation of bis(monoacylglycero)phosphate and gangliosides in mouse models of neuronal ceroid lipofuscinosis

scientific article published on 21 May 2008

Accumulation of mutant neuroserpin precedes development of clinical symptoms in familial encephalopathy with neuroserpin inclusion bodies

scientific article published on April 2007

Activation of microglia by retroviral infection correlates with transient clearance of prions from the brain but does not change incubation time.

scientific article published on 25 August 2016

Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice.

scientific article published on 12 June 2012

Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system

scientific article (publication date: 4 January 2000)

Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease

scientific article published on 20 November 2017

Amyloid-precursor-protein-lowering small molecules for disease modifying therapy of Alzheimer's disease

scientific article (publication date: 2013)

Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease

scientific article published on 02 August 2016

Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease

scientific article

Analysis of the prion protein in primates reveals a new polymorphism in codon 226 (Y226F).

scientific article published in June 2002

Antimicroglia antibodies in sera of Alzheimer's disease patients

scientific article published in February 1999

Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice

scientific article published on 19 May 2016

Association between deposition of beta-amyloid and pathological prion protein in sporadic Creutzfeldt-Jakob disease

scientific article

Autoantibodies against beta-amyloid are common in Alzheimer's disease and help control plaque burden

scientific article

BSE-associated prion-amyloid cardiomyopathy in primates

scientific article

Biomarker profile for the diagnosis of Creutzfeldt-Jakob disease

scientific article published on 13 November 2007

Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection

scientific article published in 2023

CLP1 links tRNA metabolism to progressive motor-neuron loss

scientific article published on 10 March 2013

Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease

scientific article published on 7 March 2006

Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake

scientific article published on 27 August 2020

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

scientific article

Clinical and radiological mimicry of vCJD in a valine homozygous PrP(Sc) type 1 sCJD patient

scientific article published in April 2003

Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease

scientific article published in December 2005

Comment on "Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins".

scientific article

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

scientific article published on 01 September 2018

Creutzfeldt-Jakob disease and inclusion body myositis: abundant disease-associated prion protein in muscle

scientific article

Creutzfeldt-Jakob disease mimicking autoimmune encephalitis with CASPR2 antibodies

scientific article

DNA methylation-based reclassification of olfactory neuroblastoma

scientific article published on 05 May 2018

Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

scientific article published on 9 June 2021

Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation

scientific article

Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice

scientific article published on 12 October 2014

Deletions in the spinal muscular atrophy gene region in a newborn with neuropathy and extreme generalized muscular weakness

article

Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease

scientific article published on 27 January 2011

Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease

scientific article published in July 2006

Dietary curcumin attenuates glioma growth in a syngeneic mouse model by inhibition of the JAK1,2/STAT3 signaling pathway

scientific article published on December 2010

Dissemination of Orientia tsutsugamushi and inflammatory responses in a murine model of scrub typhus.

scientific article

Distinct microglia profile in Creutzfeldt-Jakob disease and Alzheimer's disease is independent of disease kinetics

scientific article published on 15 October 2018

Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

scientific article published on 16 October 2015

Diverse functions of the prion protein - Does proteolytic processing hold the key?

scientific article

Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant

publication published on 05 June 2021

EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients

scientific article published on 15 May 2019

Early-onset stroke in two siblings with Neurofibromatosis type 1

scientific article published on 04 July 2019

Efficient chemotherapy of rat glioblastoma using doxorubicin-loaded PLGA nanoparticles with different stabilizers

scientific article

Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice

scientific article

Encephalopathy and death in infants with abusive head trauma is due to hypoxic-ischemic injury following local brain trauma to vital brainstem centers.

scientific article published on 9 August 2014

Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis

scientific article published on 16 July 2019

Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma

scientific article published on 21 December 2015

Erratum to: Encephalopathy and death in infants with abusive head trauma is due to hypoxic-ischemic injury following local brain trauma to vital brainstem centers

scientific article published in January 2015

Evidence of a pathogenic role for CD8(+) T cells in anti-GABAB receptor limbic encephalitis.

scientific article

Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity.

scientific article published on 28 December 2015

Exosomes and the Prion Protein: More than One Truth

scientific article published on 19 April 2017

Experimental chronic wasting disease (CWD) in the ferret

scientific article

Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease

scientific article

Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis

scientific article published on 24 February 2014

Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases

scientific article published on 9 May 2013

Functional characterization of the lysosomal membrane protein TMEM192 in mice

scientific article published on 28 April 2017

GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice

scientific article published on 04 January 2019

Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site

scientific article published on 19 February 2016

Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion

scientific article published on 10 February 2009

Heightened incidence of sporadic Creutzfeldt-Jakob disease is associated with a shift in clinicopathological profiles

scientific article

Hematogenous dissemination of glioblastoma multiforme.

scientific article

Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells

scientific article published on 01 April 2018

High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease.

scientific article published on 10 February 2014

Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function

scientific article

Human prion diseases: epidemiology and integrated risk assessment

scientific article published in December 2003

Human prion diseases: molecular and clinical aspects

scientific article

Human transmissible spongiform encephalopathies in eleven countries: diagnostic pattern across time, 1993-2002.

scientific article published on 10 November 2006

Hyaluronan in intra-operative edema of NF1-associated neurofibromas

scientific article published on 01 December 2011

Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells.

scientific article published on 5 September 2013

IL-17 production by CSF lymphocytes as a biomarker for cerebral vasculitis

scientific article published on 21 March 2016

IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke

scientific article published on 6 December 2017

IgG4-related hypophysitis is highly prevalent among cases of histologically confirmed hypophysitis

scientific article published on 19 November 2016

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours

scientific article published on 21 March 2019

Immune activation in amyloid-β-related angiitis correlates with decreased parenchymal amyloid-β plaque load

scientific article published on 6 September 2013

Immune system and peripheral nerves in propagation of prions to CNS.

scientific article published on January 2003

Immunochemical detection of prion protein on dipsticks prepared with crystalline bacterial cell-surface layers

scientific article published in December 2003

Immunoprofiling of glial tumours of the neurohypophysis suggests a common pituicytic origin of neoplastic cells

scientific article published on 15 October 2016

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

scientific article (publication date: 19 May 2000)

In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15.

scientific article published on 8 March 2018

Incidence of Creutzfeldt-Jakob disease in Switzerland

scientific article published in The Lancet

Increased Numbers of Injections of Doxorubicin Bound to Nanoparticles Lead to Enhanced Efficacy Against Rat Glioblastoma 101/8

Induced prion protein controls immune-activated retroviruses in the mouse spleen

scientific article

Infectious prions do not induce Aβ deposition in an in vivo seeding model

scientific article published on 16 April 2018

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

scientific article published on 05 September 2013

Intrinsic resistance of oligodendrocytes to prion infection.

scientific article published in June 2004

Inverse Perfusion Requirements of Supra- and Infratentorial Brain Metastases Formation.

scientific article published on 30 May 2018

LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance

scientific journal article

Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo

scientific article

Lectin OS-9 delivers mutant neuroserpin to endoplasmic reticulum associated degradation in familial encephalopathy with neuroserpin inclusion bodies

scientific article published on 08 April 2014

Limited Unfolded Protein Response and Inflammation in Neuroserpinopathy

scientific article published on 4 January 2016

Losing sleep over mitochondria: a new player in the pathophysiology of fatal familial insomnia

scientific article published on 28 June 2016

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.

scientific article

Mannose 6-phosphate-dependent targeting of lysosomal enzymes is required for normal craniofacial and dental development

scientific article published on 27 May 2016

Mast cell-mediated antigen presentation regulates CD8+ T cell effector functions

scientific article published on 08 October 2009

Mimicry of variant Creutzfeldt-Jakob disease by sporadic Creutzfeldt-Jakob disease: importance of the pulvinar sign

scientific article published in March 2004

Misfolding leads the way to unraveling signaling pathways in the pathophysiology of prion diseases.

scientific article published on 21 November 2016

Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada

scientific article published in May 2005

Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression

scientific article published on 30 August 2018

Myositis facilitates preclinical accumulation of pathological prion protein in muscle

scientific article published on 3 December 2013

N-glycans and glycosylphosphatidylinositol-anchor act on polarized sorting of mouse PrP(C) in Madin-Darby canine kidney cells.

scientific article

NeuroCOVID: Insights into Neuroinvasion and Pathophysiology

scientific article published on 05 April 2022

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series

scientific article published on 05 October 2020

Neuroserpin Is Strongly Expressed in the Developing and Adult Mouse Neocortex but Its Absence Does Not Perturb Cortical Lamination and Synaptic Proteome

scientific article published on 23 February 2021

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

scientific article published on 13 September 2012

No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis

scientific article

No reactivation of JCV and CMV infections in the temporal cortex and cerebellum of sporadic Creutzfeldt-Jakob disease patients

scientific article

Nonaccidental head injury is the most common cause of subdural bleeding in infants <1 year of age.

scientific article published in December 2009

Ocular pathology in shaken baby syndrome and other forms of infantile non-accidental head injury

scientific article published on 21 October 2008

Opposite roles of FOXA1 and NKX2-1 in lung cancer progression

scientific article published on 2 March 2012

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

scientific article published on 20 December 2016

Peripheral pathogenesis of prion diseases

scientific article

Persistent retroviral infection with MoMuLV influences neuropathological signature and phenotype of prion disease

scientific article published on 24 January 2012

Phenotypic profile of early-onset familial Alzheimer's disease caused by presenilin-1 E280A mutation

scientific article

Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis

scientific article published on 9 August 2013

Plasminogen activator inhibitor type 1 up-regulation is associated with skeletal muscle atrophy and associated fibrosis

scientific journal article

Plasminogen binds to disease-associated prion protein of multiple species

scientific article published in June 2001

Podoplanin and CD34 in peripheral nerve sheath tumours: focus on neurofibromatosis 1-associated atypical neurofibroma

scientific article published on 07 September 2010

Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion

scientific article published in Nature

Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions.

scientific article published in August 2013

Preclinical deposition of pathological prion protein in muscle of experimentally infected primates

scientific article

Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies.

scientific article

Prion Diseases

Prion infections, blood and transfusions

scientific article published on June 2006

Prions--role of the peripheral nervous system.

scientific article

Progressive scoliosis in central core disease

scientific article published on 31 May 2005

Protease-sensitive prion species in neoplastic spleens of prion-infected mice with uncoupling of PrP(Sc) and prion infectivity

scientific article

Recent advances on the molecular pathogenesis of prion diseases

scientific article published on 01 March 2019

Relevance of PTEN loss in brain metastasis formation in breast cancer patients

scientific article

Roles of endoproteolytic α-cleavage and shedding of the prion protein in neurodegeneration.

scientific article published on 13 March 2013

STAT3 silencing inhibits glioma single cell infiltration and tumor growth

scientific article

Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice

scientific article published on 27 April 2016

Serial EEG findings in sporadic and iatrogenic Creutzfeldt-Jakob disease

scientific article published in November 2004

Shaken baby syndrome: a common variant of non-accidental head injury in infants

scientific article published on 27 March 2009

Shedding light on prion disease.

scientific article published on 17 July 2015

Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease

scientific article published in May 2006

Specific de-SUMOylation triggered by acquisition of spatial learning is related to epigenetic changes in the rat hippocampus.

scientific article

Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging

scientific article published on 3 March 2005

Strain fidelity of chronic wasting disease upon murine adaptation ⬇️

scientific article

Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein

scientific article published on 6 April 2018

Subtypes of primary angiitis of the CNS identified by MRI patterns reflect the size of affected vessels

scientific article published on 13 July 2017

Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis

scientific article published on 15 April 2020

Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion

scientific article

Sympathetic prions

scientific article

Tenascin-R promotes neuronal differentiation of embryonic stem cells and recruitment of host-derived neural precursor cells after excitotoxic lesion of the mouse striatum

scientific article published on 22 May 2008

Testing for prions: a novel protocol for vCJD prevalence studies

scientific article published on 01 October 2004

The GPI-anchoring of PrP: implications in sorting and pathogenesis.

scientific article published on January 2014

The LPS receptor, CD14, in experimental autoimmune encephalomyelitis and multiple sclerosis

scientific article published on 14 March 2006

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

scientific article

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex

scientific article

The histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis

scientific article published on 17 October 2020

The neurological syndrome in adults during the 2011 northern German E. coli serotype O104:H4 outbreak

scientific article

The peripheral nervous system and the pathogenesis of prion diseases

scientific article published in June 2004

The serine protease inhibitor neuroserpin is required for normal synaptic plasticity and regulates learning and social behavior

scientific article published on 15 November 2017

The sheddase ADAM10 is a potent modulator of prion disease.

scientific article

The shifting biology of prions ⬇️

scientific article published on 01 October 2001

Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation

scientific article published on 04 May 2020

Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke

scientific article published on 18 September 2014

Transport and distribution of 3-hydroxyglutaric acid before and during induced encephalopathic crises in a mouse model of glutaric aciduria type 1.

scientific article published on 29 February 2008

Treatment of glioblastoma with poly(isohexyl cyanoacrylate) nanoparticles

scientific article published on 27 May 2011

Understanding the natural variability of prion diseases

scientific article

Upregulation of Shiga toxin receptor CD77/Gb3 and interleukin-1β expression in the brain of EHEC patients with hemolytic uremic syndrome and neurologic symptoms

scientific article

Vagus nerve inflammation contributes to dysautonomia in COVID-19

scientific article published in 2023

Variant Creutzfeldt-jakob disease: between lymphoid organs and brain

scientific article published in February 2004

Vascular Innervation in Benign Neurofibromas of Patients with Neurofibromatosis Type 1.

scientific article published in December 2015

Vascular endothelial growth factor, basic fibroblast growth factor and epithelial growth factor receptor in peripheral nerve sheath tumors of neurofibromatosis type 1.

scientific article published in January 2015

Vessel and Mast Cell Densities in Sporadic and Syndrome-associated Peripheral Nerve Sheath Tumors

scientific article published on September 2015

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias.

scientific article published on 10 November 2017

vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true?

scientific article published in February 2004

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