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List of works by Wolfgang Hartmann

A single nucleotide polymorphism of macrophage migration inhibitory factor is related to inflammatory response in coronary bypass surgery using cardiopulmonary bypass

scientific article published on 09 March 2006

A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del)

scientific article

Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization ⬇️

scientific article published on March 6, 2012

Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone

scientific article published on 24 January 2019

Allelic loss but absence of mutations in the polyspecific transporter gene BWR1A on 11p15.5 in hepatoblastoma

scientific article published on September 2004

Analysis of HIC-1 methylation and transcription in human ependymomas

scientific article

Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information

scientific article published on 23 March 2018

Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells

scientific article published on 19 October 2016

Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients

scientific article

Clinicopathological and molecular features of a large cohort of gastrointestinal stromal tumors (GISTs) and review of the literature: BRAF mutations in KIT/PDGFRA wild-type GISTs are rare events

scientific article published on 31 January 2017

Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas

scientific article

Combinatorial effects of doxorubicin and retargeted tissue factor by intratumoral entrapment of doxorubicin and proapoptotic increase of tumor vascular infarction

scientific article published on 11 October 2016

Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes

scientific article published on 11 September 2019

DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma

scientific article published on 20 March 2019

Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma

scientific article

Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells

scientific article

Differential Pi3K-pathway activation in cortical tubers and focal cortical dysplasias with balloon cells

scientific article published in April 2007

Differential diagnosis of solitary fibrous tumors: A study of 454 soft tissue tumors indicating the diagnostic value of nuclear STAT6 relocation and ALDH1 expression combined with in situ proximity ligation assay

scientific article

Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts

scientific article published on 23 December 2010

Elevated expression of Wnt antagonists is a common event in hepatoblastomas

scientific article

Endometrial stromal sarcomas with BCOR-rearrangement harbor MDM2 amplifications

scientific article published on 30 April 2020

Epigenetic control over the cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia

scientific article published in 2024

FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma

scientific article published on 21 June 2017

Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas

scientific article

Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

scientific article published in Nature Communications

HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat

scientific article published on 05 February 2016

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

scientific article

IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a.

scientific article published on July 2000

IGF-II enhances trichostatin A-induced TGFbeta1 and p21(Waf1,Cip1, sdi1) expression in Hep3B cells

scientific article published in December 1999

Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells

scientific article

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

scientific article

Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas

scientific article published on 17 December 2013

KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy

scientific article published on 15 July 2019

Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors

scientific article published on 29 April 2011

MiR-34a deficiency accelerates medulloblastoma formation in vivo

scientific article

MicroRNA profiling of primary high-grade soft tissue sarcomas

scientific article

Molekularpathologie von Sarkomen

Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas

scientific article

Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas

scientific article published on July 2007

NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas ⬇️

scientific article published on 4 September 2015

No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours

scientific article

PD-1 and PD-L1 Expression in NSCLC Indicate a Favorable Prognosis in Defined Subgroups

scientific article

Perioperative chemotherapy in gastroesophageal cancer. A retrospective monocenter evaluation of 42 cases

scientific article

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

scientific article

Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.

scientific article published on May 2006

Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone

scientific article published on 23 December 2019

Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91.

scientific article published on May 2007

Prognostic relevance of global histone H3 lysine 4 (H3K4) methylation in renal cell carcinoma

scientific article published in November 2010

ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability

scientific article published in April 2015

Requirement for YAP1 signaling in myxoid liposarcoma

scientific article published on 01 May 2019

Resistance to avapritinib in PDGFRA-driven GIST is caused by secondary mutations in the PDGFRA kinase domain

scientific article published on 24 September 2020

SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas.

scientific article

SRC signaling is crucial in the growth of synovial sarcoma cells

scientific article published on 11 April 2013

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML

scientific article published on 02 August 2019

Subtype-specific expression and genetic alterations of the chemokinereceptor gene CXCR4 in medulloblastomas.

scientific article published in October 2005

TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities

scientific article

Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity

scientific article

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G.

scientific article published on 28 October 2016

The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies

scientific article published on 25 May 2021

The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo

scientific article

Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer

scientific article published on 16 September 2021

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