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List of works by Nigel J. Temperton

A Lentiviral Pseudotype ELLA for the Measurement of Antibodies Against Influenza Neuraminidase

A naturally protective epitope of limited variability as an influenza vaccine target

scientific article published in Nature Communications

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

scientific article

A potent neutralizing epitope of limited variability in the head domain of haemagglutinin as a novel influenza vaccine target

A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies

scientific article published on May 2007

Activation of antigen-presenting cells by endogenous retroviral RNA.

scientific article published on 17 February 2005

Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue in vitro by Modified Vaccinia Ankara-vectored influenza vaccines.

scientific article

Adjuvant-free immunization with hemagglutinin-Fc fusion proteins as an approach to influenza vaccines

scientific article published on 29 December 2010

An Optimized Method for the Production Using PEI, Titration and Neutralization of SARS-CoV Spike Luciferase Pseudotypes

An optimised method for the production of MERS-CoV spike expressing viral pseudotypes

scientific article published on 13 October 2015

Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN study

scientific article published in 2022

Antigenic drift in H5N1 avian influenza virus in poultry is driven by mutations in major antigenic sites of the hemagglutinin molecule analogous to those for human influenza virus

scientific article

Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry

scientific article published on 29 January 2015

Bat and pig IFN-induced transmembrane protein 3 restrict cell entry by influenza virus and lyssaviruses

scientific article published on 22 January 2015

ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice ⬇️

scientific article published on June 2017

Characterisation of SARS-CoV-2 Lentiviral Pseudotypes and Correlation between Pseudotype-Based Neutralisation Assays and Live Virus-Based Micro Neutralisation Assays

scientific article published on 10 September 2020

Chicken interferon-inducible transmembrane protein 3 restricts influenza viruses and lyssaviruses in vitro

scientific article published on 25 September 2013

Chimeric influenza haemagglutinins: Generation and use in pseudotype neutralization assays

scientific article

Cloning of an Fe-superoxide dismutase gene homologue from Trypanosoma cruzi.

scientific article published on February 1996

Comparative serological assays for the study of h5 and h7 avian influenza viruses.

scientific article

Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines

article

Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin

scientific article published on 10 February 2019

Cross-protective immune responses induced by sequential influenza virus infection and by sequential vaccination with inactivated influenza vaccines

article

Cross-reactive immunity against influenza viruses in children and adults following 2009 pandemic H1N1 infection.

scientific article

Current progress with serological assays for exotic emerging/re-emerging viruses

article published in 2013

DNA vaccines against cytomegalovirus: current progress.

scientific article

Detection of antibodies against H5 and H7 strains in birds: evaluation of influenza pseudovirus particle neutralization tests.

scientific article published on 15 January 2014

Development and use of Lentiviral Vectors Pseudotyped with Influenza B Haemagglutinins: application to vaccine immunogenicity, mAb potency and sero-surveillance studies

Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens

scientific article published on 14 December 2020

Discordant correlation between serological assays observed when measuring heterosubtypic responses against avian influenza H5 and H7 viruses in unexposed individuals.

scientific article

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection

scientific article published on 01 December 2020

Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation

scientific article

Ebolavirus: pseudotypes, libraries and standards

Enhancement of humoral immune responses to a human cytomegalovirus DNA vaccine: Adjuvant effects of aluminum phosphate and CpG oligodeoxynucleotides

article

Entry of the bat influenza H17N10 virus into mammalian cells is enabled by the MHC class II HLA-DR receptor

scientific article published on 29 July 2019

Epidemiology of herpes simplex virus type 1 and 2 in Italy: a seroprevalence study from 2000 to 2014.

scientific article

Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection

scientific article published on 21 August 2020

Exploiting viral pseudotypes for emerging virus research

scholarly article by K. Grehan et al published December 2016 in International Journal of Infectious Diseases

Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses

scientific article published in 2022

Further antibody escape by Omicron BA.4 and BA.5 from vaccine and BA.1 serum

Hemagglutinin Sequence Conservation Guided Stem Immunogen Design from Influenza A H3 Subtype

scientific article

Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

scientific article

Human monoclonal antibodies in single chain fragment variable format with potent neutralization activity against influenza virus H5N1.

scientific article

Humoral Immunogenicity and Efficacy of a Single Dose of ChAdOx1 MERS Vaccine Candidate in Dromedary Camels

scientific article published on 08 November 2019

Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry

scientific article published on 20 February 2019

Improved adjuvanting of seasonal influenza vaccines: preclinical studies of MVA-NP+M1 coadministration with inactivated influenza vaccine

scientific article

In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses.

scientific article

Induction of broad immunity by thermostabilised vaccines incorporated in dissolvable microneedles using novel fabrication methods

scientific article published on 13 January 2016

Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses.

scientific article

Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection

scientific article

Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens

scientific article published on 5 February 2018

Investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison

scientific article

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules

scientific article (publication date: April 2011)

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

scientific article published on 26 October 2020

Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes

scientific article published in March 2005

Lyophilisation of influenza, rabies and Marburg lentiviral pseudotype viruses for the development and distribution of a neutralisation -assay-based diagnostic kit.

scientific article published on 5 October 2014

Multiplex evaluation of influenza neutralizing antibodies with potential applicability to in-field serological studies

scientific article

Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility

scientific article

Nanobodies with in vitro neutralizing activity protect mice against H5N1 influenza virus infection

scientific article

Neutralising antibodies to SARS coronavirus 2 in Scottish blood donors - a pilot study of the value of serology to determine population exposure

scientific article published on 17 April 2020

Neutralizing monoclonal antibodies to different clades of Influenza A H5N1 viruses

scientific article published on 17 January 2009

Novel Bivalent Viral-Vectored Vaccines Induce Potent Humoral and Cellular Immune Responses Conferring Protection against Stringent Influenza A Virus Challenge.

scientific article

Optimisation of equine influenza pseudotyped virus production

article

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future

scientific article published on 13 October 2014

Potent cross-reactive antibodies following Omicron breakthrough in vaccinees

scientific article published on 20 May 2022

Production of lentiviral vectors pseudotyped with influenza neuraminidase (NA) v1 (protocols.io.rkkd4uw)

Pseudotype Neutralization Assays: From Laboratory Bench to Data Analysis

scientific article published on 22 January 2018

Pseudotype-based neutralization assays for influenza: a systematic analysis.

scientific article

Retroviral Pseudotypes

Retroviral Pseudotypes - From Scientific Tools to Clinical Utility

SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies

scientific article

SARS-CoV-2 evolution during treatment of chronic infection

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

scientific article

Society of General Microbiology--2009 spring meeting.

scientific article published in May 2009

Stalking influenza by vaccination with pre-fusion headless HA mini-stem

scientific article

Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody

scientific article published on 13 July 2015

T cell responses to whole SARS coronavirus in humans

scientific article published on October 2008

Technical considerations for the generation of novel pseudotyped viruses

The MHC class-II HLA-DR receptor mediates bat influenza A-like H17N10 virus entry into mammalian cells

The Optimisation of Pseudotyped Viruses for the Characterisation of Immune Responses to Equine Influenza Virus.

scientific article published on 15 December 2016

The Use of Hyperimmune Chicken Reference Sera Is Not Appropriate for the Validation of Influenza Pseudotype Neutralization Assays

scientific article published on 25 September 2017

The Use of Retroviral Pseudotypes for the Measurement of Antibody Responses to SARS Coronavirus

article

The Viral Pseudotype Unit: viral pseudotype R&D, dissemination and education

The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants

scientific article published on 27 November 2021

The application of pseudotypes to influenza pandemic preparedness

article published in 2015

The contribution of specific haemagglutinin mutations to equine influenza vaccine breakdown

The distribution of the endogenous retroviruses HERV-K113 and HERV-K115 in health and disease

scientific article published on September 2005

The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes ⬇️

scientific article published on January 1, 2012

The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses

scientific article

The study of antibody responses to influenza neuraminidase using a lentiviral pseudotype based ELLA

article

The use of equine influenza pseudotypes for serological screening

scientific article published on 31 December 2012

The use of hyperimmune chicken reference sera is not appropriate for the validation of influenza pseudotype neutralization assays

The use of pseudotypes to study viruses, virus sero-epidemiology and vaccination

scientific article published on 30 April 2015

Type I feline coronavirus spike glycoprotein fails to recognize aminopeptidase N as a functional receptor on feline cell lines

scientific article

Virus neutralising activity of African fruit bat (Eidolon helvum) sera against emerging lyssaviruses

scientific article published on 15 October 2010

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