Search filters

List of works by Dik-Lung Ma

2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells

scientific article published on 20 January 2016

5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

scientific article published on 27 September 2008

A G-pentaplex-based assay for Cs(+) ions in aqueous solution using a luminescent Ir(III) complex

scientific article published on 22 October 2015

A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity

scientific article published on 25 July 2016

A Highly Selective and Non-Reaction Based Chemosensor for the Detection of Hg2+ Ions Using a Luminescent Iridium(III) Complex ⬇️

scientific article published on March 22, 2013

A Metal‐Based Inhibitor of Tumor Necrosis Factor‐α ⬇️

scientific article published on July 13, 2012

A Novel Tetradentate Ruthenium(II) Complex Containing Tris(2- Pyridylmethyl)amine (tpa) As An Inhibitor Of Beta-amyloid Fibrillation

scientific article

A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease

scientific article

A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells.

scientific article published on 20 February 2017

A bifunctional platinum(II) complex capable of intercalation and hydrogen-bonding interactions with DNA: binding studies and cytotoxicity

scientific article published on December 2003

A colorimetric chemosensor for Cu²⁺ ion detection based on an iridium(III) complex

scientific article

A dicationic organoplatinum(II) complex containing a bridging 2,5-bis-(4-ethynylphenyl)-[1,3,4]oxadiazole ligand behaves as a phosphorescent gelator for organic solvents

scientific article

A gold(III) porphyrin complex with antitumor properties targets the Wnt/beta-catenin pathway

scientific article

A highly selective G-quadruplex-based luminescent switch-on probe for the detection of gene deletion

scientific article published on 01 October 2012

A highly selective luminescent switch-on probe for histidine/histidine-rich proteins and its application in protein staining

scientific article published in January 2008

A highly selective, label-free, homogenous luminescent switch-on probe for the detection of nanomolar transcription factor NF-kappaB ⬇️

scientific article published on March 11, 2011

A highly sensitive G-quadruplex-based luminescent switch-on probe for the detection of polymerase 3'-5' proofreading activity

scientific article

A label-free G-quadruplex-based luminescent switch-on assay for the selective detection of histidine

scientific article published on 24 July 2013

A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T-Hg2+-T mismatched DNA.

scientific article

A label-free luminescent switch-on assay for ATP using a G-quadruplex-selective iridium(III) complex

scientific article

A label-free triplex-to-G-qadruplex molecular switch for sensitive fluorescent detection of acetamiprid

scientific article published on 12 July 2018

A long lifetime luminescent iridium(III) complex chemosensor for the selective switch-on detection of Al(3+) ions.

scientific article published in March 2016

A long lifetime switch-on iridium(III) chemosensor for the visualization of cysteine in live zebrafish

scientific article published on 01 March 2016

A long-lived peptide-conjugated iridium(iii) complex as a luminescent probe and inhibitor of the cell migration mediator, formyl peptide receptor 2

scientific article published on 01 October 2018

A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe

scientific article

A metal-based inhibitor of NEDD8-activating enzyme

scientific article

A metal-based tumour necrosis factor-alpha converting enzyme inhibitor.

scientific article

A natural product-like inhibitor of NEDD8-activating enzyme

scientific article published on 14 January 2011

A parallel G-quadruplex-selective luminescent probe for the detection of nanomolar calcium(II) ion.

scientific article published on 19 July 2013

A selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar silver(I) ions in aqueous solution

scientific article published on 29 July 2010

A selective oligonucleotide-based luminescent switch-on probe for the detection of nanomolar mercury(II) ion in aqueous solution

scientific article published on 24 September 2009

A suspending-droplet mode paper-based microfluidic platform for low-cost, rapid, and convenient detection of lead(II) ions in liquid solution

scientific article

A tutorial review for employing enzymes for the construction of G-quadruplex-based sensing platforms

scientific article published on 28 January 2016

Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis

scientific article published on 2 March 2010

Alkene cyclopropanation catalyzed by Halterman iron porphyrin: participation of organic bases as axial ligands

scientific article published on 22 August 2006

Aminoglycosylation can enhance the G-quadruplex binding activity of epigallocatechin

scientific article

An Ir(III) complex chemosensor for the detection of thiols

scientific article published on 06 April 2016

An Iridium(III) Complex Inhibits JMJD2 Activities and Acts as a Potential Epigenetic Modulator

scientific article published on 30 July 2015

An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB.

scientific article published on 16 March 2017

An iridium(iii)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent

scientific article published on 30 July 2015

Antagonizing STAT3 dimerization with a rhodium(III) complex

scientific article published on 30 May 2014

Antcamphorols A-K, Cytotoxic and ROS Scavenging Triterpenoids from Antrodia camphorata

scientific article published on 31 December 2019

Anti-Fatigue Effects of the Unique Polysaccharide Marker of Dendrobium officinale on BALB/c Mice.

scientific article published on 18 January 2017

Bis-intercalative dinuclear platinum(II) 6-phenyl-2,2'-bipyridine complexes exhibit enhanced DNA affinity but similar cytotoxicity compared to the mononuclear unit

scientific article published on 22 July 2003

Butyrate mediates nucleotide-binding and oligomerisation domain (NOD) 2-dependent mucosal immune responses against peptidoglycan

scientific article published in December 2009

Cell imaging of dopamine receptor using agonist labeling iridium(iii) complex.

scientific article published on 19 December 2017

Chemical Structure and Immunomodulating Activities of an α-Glucan Purified from Lobelia chinensis Lour.

scientific article

Combination of i-motif and G-quadruplex structures within the same strand: formation and application.

scientific article published on 14 June 2013

Comprehensive quantitative analysis of Chinese patent drug YinHuang drop pill by ultra high-performance liquid chromatography quadrupole time of flight mass spectrometry

scientific article published on 08 April 2016

Comprehensive quantitative analysis of Shuang-Huang-Lian oral liquid using UHPLC-Q-TOF-MS and HPLC-ELSD.

scientific article published on 30 August 2014

Construction of a Nano Biosensor for Cyanide Anion Detection and Its Application in Environmental and Biological Systems

scientific article published on 26 September 2017

Cyclometalated gold(III) complexes with N-heterocyclic carbene ligands as topoisomerase I poisons

scientific article published on 19 April 2010

Cyclometalated platinum(II) complexes as highly sensitive luminescent switch-on probes for practical application in protein staining and cell imaging

scientific article published in January 2009

DNA binding and cytotoxicity of ruthenium(II) and rhenium(I) complexes of 2-amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine.

scientific article published on February 2007

Destiny of Dendrobium officinale Polysaccharide after Oral Administration: Indigestible and Nonabsorbing, Ends in Modulating Gut Microbiota

scientific article published on 08 May 2019

Detection of 3'→5' exonuclease activity using a metal-based luminescent switch-on probe

scientific article published on 21 August 2013

Determination of cell metabolite VEGF₁₆₅ and dynamic analysis of protein-DNA interactions by combination of microfluidic technique and luminescent switch-on probe

scientific article published on 30 November 2015

Development of a Long-Lived Luminescence Probe for Visualizing β-Galactosidase in Ovarian Carcinoma Cells

scientific article

Development of an Aptamer-Based Sensing Platform for Metal Ions, Proteins, and Small Molecules through Terminal Deoxynucleotidyl Transferase Induced G-Quadruplex Formation

scientific article published on 9 October 2015

Development of an Iridium(III) Complex as a G-Quadruplex Probe and Its Application for the G-Quadruplex-Based Luminescent Detection of Picomolar Insulin

article

Discovery of a Natural Product-Like c-myc G-Quadruplex DNA Groove-Binder by Molecular Docking ⬇️

scientific article published on August 17, 2012

Discovery of a drug-like G-quadruplex binding ligand by high-throughput docking

scientific article published on 01 June 2008

Discovery of a natural product-like iNOS inhibitor by molecular docking with potential neuroprotective effects in vivo

scientific article

Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening

scientific article published on 24 August 2014

Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme

scientific article published on 4 September 2014

Drug repositioning by structure-based virtual screening ⬇️

scientific article published on January 4, 2013

Dual Inhibition And Monitoring Of Beta-amyloid Fibrillation By A Luminescent Iridium(III) Complex

scientific article

Editorial for "Recent advances in DNA-based biosensor".

scientific article published in December 2013

Emerging Screening Approaches in the Development of Nrf2-Keap1 Protein-Protein Interaction Inhibitors

scientific article published on 10 September 2019

Engineered Amp C β-lactamase as a fluorescent screening tool for class C β-lactamase inhibitors

scientific article published on 21 February 2011

Evaluation of Cinnamomum osmophloeum Kanehira extracts on tyrosinase suppressor, wound repair promoter, and antioxidant

scientific article published on 9 March 2015

First Synthesis of an Oridonin-Conjugated Iridium(III) Complex for the Intracellular Tracking of NF-κB in Living Cells

scientific article published on 17 February 2017

Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process

scientific article published on 23 April 2008

G-quadruplexes for luminescent sensing and logic gates ⬇️

scientific article published on February 23, 2013

Gold-Catalyzed Cycloisomerization and Diels-Alder Reaction of 1,4,9-Dienyne Esters to 3 a,6-Methanoisoindole Esters with Pro-Inflammatory Cytokine Antagonist Activity

scientific article published on 15 May 2015

Group 9 organometallic compounds for therapeutic and bioanalytical applications

scientific article published on 4 November 2014

Hit identification of IKKβ natural product inhibitor ⬇️

scientific article published on January 7, 2013

Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening

scientific article

Identification of a new class of FtsZ inhibitors by structure-based design and in vitro screening

scientific article

Identification of a rhodium(iii) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells

scientific article

Identification of natural product fonsecin B as a stabilizing ligand of c-myc G-quadruplex DNA by high-throughput virtual screening

scientific article published on 09 April 2010

Iminoiodane- and Brønsted base-mediated cross dehydrogenative coupling of cyclic ethers with 1,3-dicarbonyl compounds.

scientific article published on 22 July 2015

Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes

scientific article

Inhibition of the Ras/Raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium(iii) metal-based compound.

scientific article published on 16 May 2017

Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds ⬇️

scientific article published on 13 February 2016

Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation

scientific article published on 28 June 2018

Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells

scientific article published on 28 July 2019

Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells.

scientific article published on 24 February 2016

Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe

scientific article

Label-free luminescent oligonucleotide-based probes ⬇️

scientific article published on April 21, 2013

Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex.

scientific article

Luminescence approaches for the rapid detection of disease-related receptor proteins using transition metal-based probes

scientific article published on 24 October 2019

Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe

scientific article published on 18 May 2015

Luminescent G-quadruplex Probes ⬇️

scientific article published on January 1, 2012

Luminescent Iridium(III) Complexes Supported by N-Heterocyclic Carbene-based C^C^C-Pincer Ligands and Aromatic Diimines.

scientific article published on 21 October 2015

Luminescent and colorimetric strategies for the label-free DNA-based detection of enzyme activity ⬇️

scientific article published on 08 February 2013

Luminescent chemosensors by using cyclometalated iridium(iii) complexes and their applications.

scientific article

Luminescent cyclometalated platinum(II) complexes with amino acid ligands for protein binding.

scientific article published on 5 January 2005

Luminescent detection of DNA-binding proteins

scientific article published on 03 October 2011

Luminescent ruthenium(II) complex bearing bipyridine and N-heterocyclic carbene-based C∧N∧C pincer ligand for live-cell imaging of endocytosis

scientific article

Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity

scientific article published on 21 November 2017

Mimicking Strategy for Protein-Protein Interaction Inhibitor Discovery by Virtual Screening

scientific article published on 04 December 2019

Molecular modeling of drug–DNA interactions: Virtual screening to structure-based design ⬇️

scientific article published on April 19, 2011

Monitoring of DNA-protein interaction with single gold nanoparticles by localized scattering plasmon resonance spectroscopy.

scientific article published on 14 August 2013

New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics.

scientific article

Oligonucleotide‐Based Luminescent Detection of Metal Ions ⬇️

scientific article published on February 18, 2011

Organoplatinum(II) complexes with nucleobase motifs as inhibitors of human topoisomerase II catalytic activity

scientific article published on October 2010

PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells.

scientific article

Pathologically activated neuroprotection via uncompetitive blockade of N-methyl-D-aspartate receptors with fast off-rate by novel multifunctional dimer bis(propyl)-cognitin

scientific article

Phosphorescent imaging of living cells using a cyclometalated iridium (III) complex

scientific article

Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells.

scientific article published on 23 November 2015

Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways

scientific article

Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells.

scientific article published on 24 May 2016

Purified Astaxanthin from Haematococcus pluvialis Promotes Tissue Regeneration by Reducing Oxidative Stress and the Secretion of Collagen In Vitro and In Vivo

scientific article published on 03 August 2020

Real-time detection of oxalyl chloride based on a long-lived iridium(iii) probe

scientific article published on 30 November 2017

Recent Development of G-Quadruplex Probes for Cellular Imaging.

scientific article published on January 2015

Recent advances in virtual screening for drug discovery

scientific article published on 01 January 2015

Recent progress and developments of iridium-based compounds as probes for environmental analytes

scientific article published on 01 October 2018

Rhodium complexes as therapeutic agents

scientific article

Rhodium(III)-Based Inhibitor of the JMJD3-H3K27me3 Interaction and Modulator of the Inflammatory Response

scientific article published on 30 October 2018

Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells.

scientific article

Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy

scientific article published on 19 July 2018

Silencing Stem Cell Factor Gene in Fibroblasts to Regulate Paracrine Factor Productions and Enhance c-Kit Expression in Melanocytes on Melanogenesis.

scientific article

Specific blocking of CREB/DNA binding by cyclometalated platinum(II) complexes

scientific article published on 18 February 2011

Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives

scientific article

Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression

scientific article published on December 2009

Stable anticancer gold(III)-porphyrin complexes: effects of porphyrin structure

scientific article

Structure Characterization and Immunomodulating Effects of Polysaccharides Isolated from Dendrobium officinale.

scientific article published on 11 January 2016

Structure-based design of platinum(II) complexes as c-myc oncogene down-regulators and luminescent probes for G-quadruplex DNA.

scientific article published on June 2010

Structure-based discovery of an immunomodulatory inhibitor of TLR1-TLR2 heterodimerization from a natural product-like database

scientific article published on 01 June 2015

Structure-based discovery of natural-product-like TNF-α inhibitors

scientific article published on 16 March 2010

Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer

scientific article published on 4 March 2011

Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme

scientific article published on 19 March 2014

Structure-based screening and optimization of cytisine derivatives as inhibitors of the menin-MLL interaction

scientific article published on 23 March 2016

Structure‐Based Repurposing of FDA‐Approved Drugs as TNF‐α Inhibitors ⬇️

scientific article published on May 2, 2011

Synthesis and biological activity of a platinum(II) 6-phenyl-2,2'-bipyridine complex and its dimeric analogue

scientific article

TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells.

scientific article published on 29 December 2015

Time-Resolved Luminescent High-Throughput Screening Platform for Lysosomotropic Compounds in Living Cells

scientific article published on 28 December 2020

Transition metal complexes as imaging or therapeutic agents for neurodegenerative diseases

scientific article published on 26 February 2020

Turn-on Luminescent Probe for Hydrogen Peroxide Sensing and Imaging in Living Cells based on an Iridium(III) Complex-Silver Nanoparticle Platform

scientific article published on 21 August 2017

UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids

scientific article published on 16 July 2018

Visualization of Zn²⁺ ions in live zebrafish using a luminescent iridium(III) chemosensor

scientific article published in August 2014

Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: photoluminescent properties and cytotoxicities.

scientific article

Paulina is supported by:

About Paulina

Help