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List of works by Antonio Cuadrado

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

scientific article published in July 1998

Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

scientific article

Activation of autophagy in macrophages by pro-resolving lipid mediators.

scientific article

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

scientific article published on 14 July 2019

Acylphosphatase synergizes with progesterone during maturation of Xenopus laevis oocytes

scientific article published in August 1993

Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line

scientific article

Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice

scientific article published on 13 May 2015

Analysis of growth components in Allium roots

scientific article

Antioxidants in Translational Medicine

scientific article

Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimer's disease

scientific article

Cell size of proliferating plant cells increases with temperature: Implications in the control of cell division

article

Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.

scientific article

Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells

scientific article

Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats

scientific article published on 22 August 2007

Clinical Relevance of Biomarkers of Oxidative Stress

scientific article

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

scientific article published on 26 October 2017

Deficiency of Nrf2 Accelerates the Effector Phase of Arthritis and Aggravates Joint Disease

scientific article published on 25 May 2011

Different susceptibility to the Parkinson's toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1

scientific article

Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells

scientific article

Effects of Nrf2 deficiency on bone microarchitecture in an experimental model of osteoporosis

scientific article

Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes

scientific article

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Expression of protein kinase CI in NIH 3T3 cells increases its growth response to specific activators.

scientific article published on January 1990

Fibroblast growth factor-1 within the ventral tegmental area participates in motor sensitizing effects of morphine

scientific article published on 9 October 2009

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis.

scientific article published on 25 November 2013

Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death

scientific article published on 20 June 2008

GSK-3beta down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress.

scientific article published on 13 November 2007

Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2.

scientific article published on 21 March 2006

Haeme oxygenase-1 overexpression via nAChRs and the transcription factor Nrf2 has antinociceptive effects in the formalin test

scientific article published on 5 August 2009

Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections

scientific article published on January 2008

Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E(2) production in osteoarthritic chondrocytes.

scientific article

Increased tyrosine phosphorylation in ras transformed fibroblasts occurs prior to manifestation of the transformed phenotype

scientific article published on July 1990

Influence of cell size on differentiation of root meristem cells

Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.

scientific article

Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor

scientific article published on 13 February 2006

Interleukin-1beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase/Akt pathway: relevance to sepsis-associated encephalopathy

scientific article published on 27 March 2006

Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action

scientific article

NRF2 and Primary Cilia: An Emerging Partnership

scientific article published on 02 June 2020

Nerve growth factor protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a phosphatidylinositol 3-kinase-dependent manner

scientific article

Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

scientific article published on 16 January 2014

Nicotinic receptor activation by epibatidine induces heme oxygenase-1 and protects chromaffin cells against oxidative stress

Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress

scientific article

Nrf2 deficiency potentiates methamphetamine-induced dopaminergic axonal damage and gliosis in the striatum.

scientific article

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.

scientific article

Nrf2 participates in depressive disorders through an anti-inflammatory mechanism

scientific article

Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: A positive regulator role of Nrf2 on cytokine release.

scientific article published on 26 February 2014

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.

scientific article

Nrf2-mediated haeme oxygenase-1 up-regulation induced by cobalt protoporphyrin has antinociceptive effects against inflammatory pain in the formalin test in mice

scientific article published on 26 October 2007

Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative stress.

scientific article

Partial elimination of G1 and G2 periods in higher plant cells by increasing the S period

article

Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice

scientific article published in October 2006

Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism.

scientific article published on 28 March 2011

Pharmacology and Clinical Drug Candidates in Redox Medicine

scientific article

Platelet-derived growth factor stimulation of GTPase-activating protein tyrosine phosphorylation in control and c-H-ras-expressing NIH 3T3 cells correlates with p21ras activation ⬇️

scientific article published on September 1, 1992

Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice.

scientific article

Protein kinase Akt/PKB phosphorylates heme oxygenase-1 in vitro and in vivo

scientific article

Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity.

scientific article published on 9 May 2013

RETRACTED: 6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-κB factors

retracted scientific article

RETRACTED: S-allyl cysteine protects against 6-hydroxydopamine-induced neurotoxicity in the rat striatum: involvement of Nrf2 transcription factor activation and modulation of signaling kinase cascades

retracted article

Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications

scientific article

Redox control of microglial function: molecular mechanisms and functional significance

scientific article

Redox control of protein degradation

scientific article published in December 2015

Regulation of Cu/Zn-Superoxide Dismutase Expression via the Phosphatidylinositol 3 Kinase/Akt Pathway and Nuclear Factor- B

scientific article published on 01 August 2004

Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol

scientific article

Regulation of heme oxygenase-1 gene expression through the phosphatidylinositol 3-kinase/PKC-zeta pathway and Sp1.

scientific article published on 21 April 2006

Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner.

scientific article published on 28 April 2015

Role of microglial redox balance in modulation of neuroinflammation.

scientific article published on June 2009

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

scientific article published on 18 January 2011

Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.

scientific article published on 12 November 2011

Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1.

scientific article published on 11 February 2004

Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP.

scientific article published on 29 April 2015

Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis

scientific article

TAZ Represses the Neuronal Commitment of Neural Stem Cells

scientific article published on 02 October 2020

The PTEN/NRF2 axis promotes human carcinogenesis

scientific article

The Role of Free Radicals in Autophagy Regulation: Implications for Ageing

scientific article published on 26 February 2018

The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta: connecting neurotransmission with neuroprotection.

scientific article published on 12 June 2009

The probability of G1 cells to enter into S increases with their size while S length decreases with cell enlargement in Allium cepa

scientific article

The probability of G1 cells to enter into S increases with their size while S length decreases with cell enlargement in Allium cepa

The purinergic P2Y(13) receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death

scientific article published on 4 May 2010

The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease

scholarly article by Antonio Cuadrado et al published March 2009 in Expert Opinion on Therapeutic Targets

Transcription Factor NRF2 Participates in Cell Cycle Progression at the Level of G1/S and Mitotic Checkpoints

scientific article published on 11 May 2022

Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation

scientific article

Uneven distribution of protein kinase C-alpha and -beta isozymes in human sarcomas and carcinomas

scientific article published on June 1994

WIP Modulates Oxidative Stress through NRF2/KEAP1 in Glioblastoma Cells

scientific article published on 20 August 2020

WNT-3A regulates an Axin1/NRF2 complex that regulates antioxidant metabolism in hepatocytes.

scientific article

Whole Blood Expression Pattern of Inflammation and Redox Genes in Mild Alzheimer's Disease

scientific article published on 20 November 2021

Xanthine oxidase-derived extracellular superoxide anions stimulate activator protein 1 activity and hypertrophy in human vascular smooth muscle via c-Jun N-terminal kinase and p38 mitogen-activated protein kinases

article published in 2007

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease

scientific article published on 18 April 2012

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