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List of works by Grant N. Pierce

A comparison of adenovirally delivered molecular methods to inhibit Na+/Ca2+ exchange.

scientific article published on 3 May 2007

A new technique of coronary artery ligation: experimental myocardial infarction in rats in vivo with reduced mortality

scientific article published on 01 November 1997

A randomized trial of the effects of ezetimibe on the absorption of omega-3 fatty acids in cardiac disease patients: A pilot study.

scientific article

A review of the relative efficacy of dietary, nutritional supplements, lifestyle, and drug therapies in the management of hypertension.

scientific article

A scientific guru in India

scientific article published on 01 April 2014

A tea/vanadate decoction delivered orally over 14 months to diabetic rats induces long-term glycemic stability without organ toxicity

scientific article published on 05 December 2011

Adaptive changes in subcellular calcium transport during catecholamine-induced cardiomyopathy

scientific article published on April 1985

Adenovirally delivered shRNA strongly inhibits Na+-Ca2+ exchanger expression but does not prevent contraction of neonatal cardiomyocytes

scientific article published on 01 April 2005

Age- and sex-related differences in nuclear lipid content and nucleoside triphosphatase activity in the JCR:LA-cp corpulent rat.

scientific article published in November 1997

Alterations in adenylate cyclase activity due to streptozotocin-induced diabetic cardiomyopathy

scientific article published on March 1984

Alterations in heart and serum lysosomal activities in streptozotocin-induced diabetes

scientific article published on 01 May 1987

Alternative therapies for diabetes and its cardiac complications: role of vanadium.

scientific article published on January 2014

An international basic science and clinical research summer program for medical students

scientific article published in March 2012

Calcium and calcium-binding proteins in the nucleus

scientific article published on June 1994

Calcium is rapidly exchangeable in cultured vascular smooth muscle cells from rabbit aorta

scientific article published on 01 September 1989

Calcium movements in relation to heart function

scientific article published on March 1982

Cardiac alpha- and beta-adrenergic receptor alterations in diabetic cardiomyopathy

scientific article published on 01 November 1982

Cardiac myofibrillar ATPase activity in diabetic rats

scientific article published on 01 December 1981

Cardiovascular complications of non-insulin-dependent diabetes: the JCR:LA-cp rat.

scientific article

Cardiovascular dysfunction in insulin-dependent and non-insulin-dependent animal models of diabetes mellitus

scientific article published on April 1997

Cationic interactions with Na+-H+ exchange and passive Na+ flux in cardiac sarcolemmal vesicles

scientific article

Cells expressing unique Na+/Ca2+ exchange (NCX1) splice variants exhibit different susceptibilities to Ca2+ overload.

scientific article

Ceramide regulation of nuclear protein import

scientific article published on 14 December 2007

Chlamydia pneumoniae infection significantly exacerbates aortic atherosclerosis in an LDLR-/- mouse model within six months.

scientific article published on December 2000

Chlamydia pneumoniae stimulates proliferation of vascular smooth muscle cells through induction of endogenous heat shock protein 60.

scientific article published on 18 September 2003

Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed-enriched diet

scientific article published in April 2008

Codelivery of a tea extract prevents morbidity and mortality associated with oral vanadate therapy in streptozotocin-induced diabetic rats

scientific article published in September 2004

Comparative analysis of the phenolic content of selected Chilean, Canadian and American Merlot red wines

scientific article published in July 2003

Cost-effectiveness analysis of rheumatic heart disease prevention strategies

scientific article published on December 2013

Defective phosphatidic acid-phospholipase C signaling in diabetic cardiomyopathy

scientific article published on March 2004

Depressed phosphatidic acid-induced contractile activity of failing cardiomyocytes

scientific article published on 01 January 2003

Determining influence of oxidants on nuclear transport using digitonin-permeabilized cell assay

scientific article

Dietary flaxseed independently lowers circulating cholesterol and lowers it beyond the effects of cholesterol-lowering medications alone in patients with peripheral artery disease

scientific article published on 18 February 2015

Dietary flaxseed inhibits atherosclerosis in the LDL receptor-deficient mouse in part through antiproliferative and anti-inflammatory actions

scientific article published on 06 July 2007

Dietary hempseed reduces platelet aggregation

scientific article published on 28 November 2006

Dietary vaccenic acid has antiatherogenic effects in LDLr-/- mice.

scientific article

Differential antioxidant properties of red wine in water soluble and lipid soluble peroxyl radical generating systems

scientific article published in August 2004

Differential effects of trans and polyunsaturated fatty acids on ischemia/ reperfusion injury and its associated cardiovascular disease states

scientific article published in January 2013

Differential sensitivities of the NCX1.1 and NCX1.3 isoforms of the Na+-Ca2+ exchanger to alpha-linolenic acid

scientific article published on 23 September 2006

Dissemination of Chlamydia pneumoniae to the vessel wall in atherosclerosis

scientific article

Distribution of omega-3 fatty acids in tissues of rabbits fed a flaxseed-supplemented diet

scientific article published on 14 November 2009

Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury

scientific article published on 22 November 2006

Effect of flax addition on the flavor profile and acceptability of bagels

scientific article

Effect of high-dose verapamil administration on the Ca2+ channel density in rat cardiac tissue.

scientific article

Effect of platelet-activating factor (PAF) on sodium calcium exchange in cardiac sarcolemmal vesicles

scientific article published on 01 January 1990

Effective control of glycemic status and toxicity in Zucker diabetic fatty rats with an orally administered vanadate compound

scientific article published in October 2004

Effects of cholesterol oxidase on cultured vascular smooth muscle cells

scientific article published on November 13, 1991

Effects of dietary flaxseed on atherosclerotic plaque regression

scientific article published on 12 April 2013

Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits

scientific article published on 14 July 2006

Effects of long-term consumption of a high-fructose diet on conventional cardiovascular risk factors in Sprague-Dawley rats

scientific article published on 24 February 2009

Effects of mitogen-activated protein kinases on nuclear protein import.

scientific article

Effects of oxidative modification of cholesterol in isolated low density lipoproteins on cultured smooth muscle cells

scientific article published in November 1991

Elevated levels of pro-inflammatory oxylipins in older subjects are normalized by flaxseed consumption

scientific article published on 18 April 2014

Endothelin-1 induced hypertrophic effect in neonatal rat cardiomyocytes: Involvement of Na+/H+ and Na+/Ca2+ exchangers

scientific article published in November 2006

Experimental and clinical research findings on the cardiovascular benefits of consuming flaxseed.

scientific article published in October 2009

Extensive autolytic fragmentation of membranous versus cytosolic calpain following myocardial ischemia-reperfusion

scientific article published in May 2010

FGF-2-induced Negative Inotropism and Cardioprotection are Inhibited by Chelerythrine: Involvement of Sarcolemmal Calcium-independent Protein Kinase C

scientific article published on 01 December 1998

Flaxseed consumption reduces blood pressure in patients with hypertension by altering circulating oxylipins via an α-linolenic acid-induced inhibition of soluble epoxide hydrolase.

scientific article published on 28 April 2014

Flaxseed for hypertension: implications for blood pressure regulation

scientific article

Heat-inactivated C. pneumoniae organisms are not atherogenic.

scientific article published on May 2004

Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats.

scientific article published on December 2007

Hydrogen peroxide inhibition of nuclear protein import is mediated by the mitogen-activated protein kinase, ERK2.

scientific article published on January 2000

Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors

scientific article published on 11 January 2005

Immunofluorescence imaging as a tool for studying the pharmacokinetics of a human monoclonal single chain fragment antibody

scientific article published on 01 October 2002

Increased homocysteine-induced release of excitatory amino acids in the striatum of spontaneously hypertensive stroke-prone rats

scientific article published on 14 June 2008

Induction of expression of the sodium-hydrogen exchanger in rat myocardium

scientific article published on 01 February 1995

Inhibition of Na(+)/H(+) exchange at the beginning of reperfusion is cardioprotective in isolated, beating adult cardiomyocytes

scientific article published on 01 October 2000

Involvement of caveolin in probucol-induced reduction in hERG plasma-membrane expression

scientific article published on 28 January 2011

Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processes

scientific article

Is open-access publishing the wave of the future in science?

scientific article published in May 2014

Lack of effect of prostaglandins on rat heart myofibrillar ATPase activity

scientific article published on June 1981

Lessons from the glitazones

scientific article published on 01 October 2001

Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat.

scientific article

Low n-6:n-3 fatty acid ratio, with fish- or flaxseed oil, in a high fat diet improves plasma lipids and beneficially alters tissue fatty acid composition in mice

scientific article published in April 2008

Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells

scientific article published on 01 March 1998

Lysophospholipids do not directly modulate Na(+)-H+ exchange

scientific article published in September 2003

Mitogen activated protein kinase at the nuclear pore complex

scientific article published on April 2011

Na(+)-Ca2+ exchange and Ca2+ channel characteristics in bovine aorta and coronary artery smooth muscle sarcolemmal membranes

scientific article published on 01 March 1995

Na(+)-H+ exchange inhibition at reperfusion is cardioprotective during myocardial ischemia-reperfusion; 31P NMR studies

scientific article published on 01 November 1997

Na+-H+ exchange in cardiac sarcolemmal vesicles

scientific article published on August 1985

Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels

scientific article published in July 2003

Noninvasive localization of tumors by immunofluorescence imaging using a single chain Fv fragment of a human monoclonal antibody with broad cancer specificity

scientific article published on 01 September 2000

Nuclear cholesterol content and nucleoside triphosphatase activity are altered in the JCR:LA-cp corpulent rat

scientific article published on 01 December 1996

Nuclear membrane cholesterol can modulate nuclear nucleoside triphosphatase activity

scientific article published on 01 December 1996

Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts

scientific journal article

Nucleolin is a calcium-binding protein

scientific journal article

Nucleoplasmic calcium regulation in rabbit aortic vascular smooth muscle cells

scientific article published on March 1, 2003

Nutrition as a vehicle for cardiovascular translational research.

scientific article published on 12 June 2009

On being scientifically different.

scientific article

On meetings and conferences: is bigger really better?

scientific article published on 01 July 2014

Oxidation of nuclear membrane cholesterol inhibits nucleoside triphosphatase activity

scientific article published on 01 January 1997

Oxidative status of lipoproteins in coronary disease patients

scientific article published on 01 February 1992

Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import

scientific article

Oxidized LDL enhances stretch-induced smooth muscle cell proliferation through alterations in nuclear protein import

scientific article published on 29 November 2012

Oxidized LDL promotes the mitogenic actions of Chlamydia pneumoniae in vascular smooth muscle cells.

scientific article published on December 2011

Oxidized low-density lipoprotein retards the growth of proliferating cells by inhibiting nuclear translocation of cell cycle proteins

scientific article published on 5 February 2004

Plasmid lipid and lipoprotein pattern in the Inuit of the Keewatin district of the Northwest territories

scientific article published on April 2003

Potent antihypertensive action of dietary flaxseed in hypertensive patients

scientific article published on 14 October 2013

Proceedings from the 2013 Canadian Nutrition Society Conference on Advances in Dietary Fats and Nutrition

article

Protection against myocardial ischemic/reperfusion injury by inhibitors of two separate pathways of Na+ entry

scientific article published in April 1998

RanGAP-mediated nuclear protein import in vascular smooth muscle cells is augmented by lysophosphatidylcholine

scientific article published on 14 November 2006

Reduced expression of the Na+/Ca2+ exchanger in adult cardiomyocytes via adenovirally delivered shRNA results in resistance to simulated ischemic injury

scientific article published on 4 December 2009

Regulation of intracellular Ca2+ in the heart during diabetes

scientific article published on April 1997

Regulation of stress-associated scaffold proteins JIP1 and JIP3 on the c-Jun NH2-terminal kinase in ischemia-reperfusion.

scientific article published on November 2010

Restoration of cardiomyocyte function in streptozotocin-induced diabetic rats after treatment with vanadate in a tea decoction

scientific article published on December 2010

Role for sulfur-containing groups in the Na+-Ca2+ exchange of cardiac sarcolemmal vesicles

scientific article published on January 1986

Role of the sodium-hydrogen exchanger in ischemia-reperfusion injury in diabetes.

scientific article

Salt in the wound: a possible role of Na+ gradient in chlamydial infection

scientific article

Short-term bioaccumulation of vanadium when ingested with a tea decoction in streptozotocin-induced diabetic rats

scientific article published in February 2006

Sodium-hydrogen exchange inhibition: pre-versus post-ischemic treatment.

scientific article

Supported liquid extraction in the quantitation of plasma enterolignans using isotope dilution GC/MS with application to flaxseed consumption in healthy adults

scientific article published in November 2012

Systematic Review and Meta-analysis of Flaxseed

scientific article published on 01 November 2015

The Grand Experiment changing peer review and the granting structure at Canada's largest funder of medical research

scientific article published on 01 June 2015

The Gretzky approach is good for business and research

scientific article published on 01 June 2014

The HYPERFlax trial for determining the anti-HYPERtensive effects of dietary flaxseed in newly diagnosed stage 1 hypertensive patients: study protocol for a randomized, double-blinded, controlled clinical trial

scientific article

The alpha linolenic acid content of flaxseed is associated with an induction of adipose leptin expression.

scientific article published on 27 October 2011

The cardiac and haemostatic effects of dietary hempseed.

scientific article

The dilemma of attending (or not) scientific conferences

scientific article published in January 2014

The effect of dietary flaxseed on improving symptoms of cardiovascular disease in patients with peripheral artery disease: rationale and design of the FLAX-PAD randomized controlled trial.

scientific article published on 17 May 2011

The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits

scientific article published in September 2011

The effect of flaxseed dose on circulating concentrations of alpha-linolenic acid and secoisolariciresinol diglucoside derived enterolignans in young, healthy adults

scientific article published on 26 March 2015

The effects of simultaneous administration of dietary conjugated linoleic acid and telmisartan on cardiovascular risks in rats

scientific article published on 7 August 2007

The importance of lipid solubility in antioxidants and free radical generating systems for determining lipoprotein proxidation

scientific article published on 01 June 1999

The nuclear membrane integrity assay

scientific article published on 01 July 1997

The nuclear protein import assay in vascular smooth muscle cells

scientific article published on 01 September 2000

The presence and partitioning of calcium binding proteins in hepatic and cardiac nuclei

scientific article published on 01 March 1996

The toxicity of dietary trans fats.

scientific article

The α-linolenic acid content of flaxseed can prevent the atherogenic effects of dietary trans fat

scientific article published on 30 September 2011

Trans fat involvement in cardiovascular disease.

scientific article published on July 2012

Trans-fatty acids in the diet stimulate atherosclerosis.

scientific article published on 23 July 2009

Two major antigens of heart sarcolemma are Ca2(+)-binding glycoproteins that copurify with the dihydropyridine receptor

scientific article published on 01 January 1991