List of works - Kurt Engeland

A CDE/CHR tandem element regulates cell cycle-dependent repression of cyclin B2 transcription.

scientific article

A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F.

scientific article published on June 1998

A single cell cycle genes homology region (CHR) controls cell cycle-dependent transcription of the cdc25C phosphatase gene and is able to cooperate with E2F or Sp1/3 sites

scientific article published on May 2002

Analysis of mono-ADP-ribosyltransferase 4 gene expression in human monocytes: splicing pattern and potential regulatory elements.

scientific article

Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.

scientific article published on 10 November 2017

Cell cycle regulation of E2F site occupation in vivo.

scientific article

Cell cycle regulation of cdc25C transcription is mediated by the periodic repression of the glutamine-rich activators NF-Y and Sp1

scientific article

Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression

scientific article

Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs

scientific article

Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements

scientific article published on 14 September 2007

Cell cycle-regulated repression of B-myb transcription: cooperation of an E2F site with a contiguous corepressor element.

scientific article published on August 1996

Characterization of two forms of the multifunctional protein acting in fatty acid beta-oxidation

scientific article published on 01 May 1988

Chimpanzee, orangutan, mouse, and human cell cycle promoters exempt CCAAT boxes and CHR elements from interspecies differences

scientific article published on 6 January 2007

Cyclin B1 transcription is enhanced by the p300 coactivator and regulated during the cell cycle by a CHR-dependent repression mechanism

scientific article published on February 2003

Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

scientific article

Cyclooxygenase-2 transcription is stimulated and amylase secretion is inhibited in pancreatic acinar cells after induction of acute pancreatitis

scientific article published on 01 November 1999

Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma

scientific article published on 01 July 2000

Differential regulation of transcription and induction of programmed cell death by human p53-family members p63 and p73.

scientific article

Evidence for domain structures of the trifunctional protein and the tetrafunctional protein acting in glyoxysomal fatty acid beta-oxidation

scientific article published on 01 December 1994

Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.

scientific article published on 14 April 2007

Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma

scientific article

Expression of p73, a novel protein related to the p53 tumour suppressor p53, and apoptosis in cholangiocellular carcinoma of the liver

scientific article published on June 1999

Expression of the cell cycle phosphatase cdc25C is down-regulated by the tumor suppressor protein p53 but not by p73

scientific article published on 01 June 2001

Expression of the p53 homologues p63 and p73 in multiple simultaneous gastric cancer

scientific article published on 01 September 2001

Gene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73.

scientific article

Genomic organization and expression of the human mono-ADP-ribosyltransferase ART3 gene.

scientific article

Human chorionic gonadotropin attracts regulatory T cells into the fetal-maternal interface during early human pregnancy

scientific article published in May 2009

Human cyclin B3. mRNA expression during the cell cycle and identification of three novel nonclassical nuclear localization signals.

scientific article

Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway

scientific article

Identification of Tcf-4 as a transcriptional target of p53 signalling

scientific article published on April 2004

Identification of two regulatory binding sites which confer myotube specific expression of the mono-ADP-ribosyltransferase ART1 gene

scientific article

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex

scientific article

Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.

scientific article

Mutation of Arg-115 of human class III alcohol dehydrogenase: a binding site required for formaldehyde dehydrogenase activity and fatty acid activation

scientific article

N- and O-glycosylation patterns and functional testing of CGB7 versus CGB3/5/8 variants of the human chorionic gonadotropin (hCG) beta subunit

scientific article published on 07 August 2020

NF-Y mediates the transcriptional inhibition of the cyclin B1, cyclin B2, and cdc25C promoters upon induced G2 arrest

scientific article published in Journal of Biological Chemistry

Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.

scientific article published on 25 September 2013

RHAMM is differentially expressed in the cell cycle and downregulated by the tumor suppressor p53.

scientific article published on 17 November 2008

Role of arginine 115 in fatty acid activation and formaldehyde dehydrogenase activity of human class III alcohol dehydrogenase

scientific article

Role of prostaglandins in regulation of pancreatic enzyme secretion by various diets

scientific article

SIRF--a novel regulator element controlling transcription from the p55Cdc/Fizzy promoter during the cell cycle

scientific article published on July 2004

Simplify p53: just an activator

scientific article

Stopping cells from dividing

scientific article published on 29 March 2016

TAp63gamma can substitute for p53 in inducing expression of the maspin tumor suppressor.

scientific article

The CCN3 gene coding for an extracellular adhesion-related protein is transcriptionally activated by the p53 tumor suppressor

scientific article

The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.

scientific article published on 7 November 2011

The CHR site: definition and genome-wide identification of a cell cycle transcriptional element

scientific article (publication date: 2014)

The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription.

scientific article published on 15 December 2009

The cyclin B2 promoter depends on NF-Y, a trimer whose CCAAT-binding activity is cell-cycle regulated

scientific article published on March 1999

The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism.

scientific article published on 29 October 2012

The glyoxysomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids

scientific article published on 01 May 1988

The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells

scientific article published on 21 September 2005

The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes

scientific article

The retinal dehydrogenase/reductase retSDR1/DHRS3 gene is activated by p53 and p63 but not by mutants derived from tumors or EEC/ADULT malformation syndromes

scientific article published on June 2010

The transcription factor p53: not a repressor, solely an activator

scientific article

The tumor suppressor p53 induces expression of the pregnancy-supporting human chorionic gonadotropin (hCG) CGB7 gene.

scientific article published on November 2011

The tumour suppressor protein p53 can repress transcription of cyclin B.

scientific article published on November 2000

Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.

scientific article

Trastuzumab therapy vs tetracycline controlled ERBB2 downregulation: influence on tumour development in an ERBB2-dependent mouse tumour model

scientific article published on 29 April 2008

p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins

scientific article published on 10 September 2010

p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements

scientific article published on 27 November 2012

p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.

scientific article

p53 signature and serous tubal in-situ carcinoma in cases of primary tubal and peritoneal carcinomas and serous borderline tumors of the ovary

scientific article published on 01 September 2011

List of works by Kurt Engeland

A CDE/CHR tandem element regulates cell cycle-dependent repression of cyclin B2 transcription.

A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F.

A single cell cycle genes homology region (CHR) controls cell cycle-dependent transcription of the cdc25C phosphatase gene and is able to cooperate with E2F or Sp1/3 sites

Analysis of mono-ADP-ribosyltransferase 4 gene expression in human monocytes: splicing pattern and potential regulatory elements.

Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.

Cell cycle regulation of E2F site occupation in vivo.

Cell cycle regulation of cdc25C transcription is mediated by the periodic repression of the glutamine-rich activators NF-Y and Sp1

Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression

Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs

Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements

Cell cycle-regulated repression of B-myb transcription: cooperation of an E2F site with a contiguous corepressor element.

Characterization of two forms of the multifunctional protein acting in fatty acid beta-oxidation

Chimpanzee, orangutan, mouse, and human cell cycle promoters exempt CCAAT boxes and CHR elements from interspecies differences

Cyclin B1 transcription is enhanced by the p300 coactivator and regulated during the cell cycle by a CHR-dependent repression mechanism

Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

Cyclooxygenase-2 transcription is stimulated and amylase secretion is inhibited in pancreatic acinar cells after induction of acute pancreatitis

Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma

Differential regulation of transcription and induction of programmed cell death by human p53-family members p63 and p73.

Evidence for domain structures of the trifunctional protein and the tetrafunctional protein acting in glyoxysomal fatty acid beta-oxidation

Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.

Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma

Expression of p73, a novel protein related to the p53 tumour suppressor p53, and apoptosis in cholangiocellular carcinoma of the liver

Expression of the cell cycle phosphatase cdc25C is down-regulated by the tumor suppressor protein p53 but not by p73

Expression of the p53 homologues p63 and p73 in multiple simultaneous gastric cancer

Gene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73.

Genomic organization and expression of the human mono-ADP-ribosyltransferase ART3 gene.

Human chorionic gonadotropin attracts regulatory T cells into the fetal-maternal interface during early human pregnancy

Human cyclin B3. mRNA expression during the cell cycle and identification of three novel nonclassical nuclear localization signals.

Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway

Identification of Tcf-4 as a transcriptional target of p53 signalling

Identification of two regulatory binding sites which confer myotube specific expression of the mono-ADP-ribosyltransferase ART1 gene

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex

Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.

Mutation of Arg-115 of human class III alcohol dehydrogenase: a binding site required for formaldehyde dehydrogenase activity and fatty acid activation

N- and O-glycosylation patterns and functional testing of CGB7 versus CGB3/5/8 variants of the human chorionic gonadotropin (hCG) beta subunit

NF-Y mediates the transcriptional inhibition of the cyclin B1, cyclin B2, and cdc25C promoters upon induced G2 arrest

Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.

RHAMM is differentially expressed in the cell cycle and downregulated by the tumor suppressor p53.

Role of arginine 115 in fatty acid activation and formaldehyde dehydrogenase activity of human class III alcohol dehydrogenase

Role of prostaglandins in regulation of pancreatic enzyme secretion by various diets

SIRF--a novel regulator element controlling transcription from the p55Cdc/Fizzy promoter during the cell cycle

Simplify p53: just an activator

Stopping cells from dividing

TAp63gamma can substitute for p53 in inducing expression of the maspin tumor suppressor.

The CCN3 gene coding for an extracellular adhesion-related protein is transcriptionally activated by the p53 tumor suppressor

The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.

The CHR site: definition and genome-wide identification of a cell cycle transcriptional element

The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription.

The cyclin B2 promoter depends on NF-Y, a trimer whose CCAAT-binding activity is cell-cycle regulated

The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism.

The glyoxysomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids

The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells

The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes

The retinal dehydrogenase/reductase retSDR1/DHRS3 gene is activated by p53 and p63 but not by mutants derived from tumors or EEC/ADULT malformation syndromes

The transcription factor p53: not a repressor, solely an activator

The tumor suppressor p53 induces expression of the pregnancy-supporting human chorionic gonadotropin (hCG) CGB7 gene.

The tumour suppressor protein p53 can repress transcription of cyclin B.

Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.

Trastuzumab therapy vs tetracycline controlled ERBB2 downregulation: influence on tumour development in an ERBB2-dependent mouse tumour model

p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins

p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements

p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.

p53 signature and serous tubal in-situ carcinoma in cases of primary tubal and peritoneal carcinomas and serous borderline tumors of the ovary