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List of works by Gianni Sava

A Cationic [60] Fullerene Derivative Reduces Invasion and Migration of HT-29 CRC Cells in Vitro at Dose Free of Significant Effects on Cell Survival

A kinetic study of the chemical stability of the antimetastatic ruthenium complex NAMI-A.

scientific article published in November 2002

A novel retinoic/butyric hyaluronan ester for the treatment of acute promyelocytic leukemia: preliminary preclinical results.

scientific article published on May 2006

A review on usnic acid, an interesting natural compound

scientific article

Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.

scientific article published on June 2004

Activity and inhibition by cytotoxic and antimetastatic drugs of cathepsin B-like cysteine proteinase in transplantable leukemias in mice

scientific article published on May 1987

Age Dependent Modification of the Metabolic Profile of the Tibialis Anterior Muscle Fibers in C57BL/6J Mice

scientific article published on 30 May 2020

Analysis of the cytotoxicity of synthetic antimicrobial peptides on mouse leucocytes: implications for systemic use.

scientific article published in September 2002

Anti-leukaemic action of RuCl2 (DMSO)4 isomers and prevention of brain involvement on P388 leukaemia and on P388/DDP subline

scientific article published in January 1993

Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers.

scientific article published on May 2003

Antiinflammatory action of hydrosoluble dimethyltriazenes on the carrageenin-induced edema in guinea pigs

scientific article published on February 1985

Antimetastatic action and hematological toxicity of p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt and 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide used as prophylactic adjuvants to surgical tumor removal in mice bearing B16 melanoma.

scientific article published on January 1984

Antimetastatic action and toxicity on healthy tissues of Na[trans-RuCl4(DMSO)Im] in the mouse

article

Antimetastatic action of orally administered lysozyme in mice bearing Lewis lung carcinoma

scientific article published on 01 May 1988

Antimetastatic action of the prostacyclin analog Iloprost in the mouse

scientific article published on 01 November 1989

Antimetastatic effects and tumor proteinase inhibition by spleen intracellular inhibitors of neutral proteinases

scientific article published on 01 December 1981

Antimetastatic effects of N-diazoacetyl-glycine derivatives in C57BL mice

scientific article

Antimetastatic properties and DNA interactions of the novel class of dimeric Ru(III) compounds Na2[{trans-RuCl4(Me2SO)}2(μ-L)] (L=ditopic, non-chelating aromatic N-ligand). A preliminary investigation

scientific article published on 01 April 2000

Antineoplastic action of egg-white lysozyme on the growth of MCa mammary carcinoma and TLX5 lymphoma in the CBA mouse

scientific article published on 01 November 1989

Antineoplastic action ofp-(3-methyl-1-triazeno)benzoic acid potassium salt, a monomethyl derivative of the antimetastatic compound DM-COOK

scientific article published on 01 January 1991

Antineoplastic activity and toxicity of an organometallic complex of ruthenium(II) in comparison with cis-PDD in mice bearing solid malignant neoplasms

article

Antineoplastic activity of planar rhodium(I) complexes in mice bearing Lewis lung carcinoma and P388 leukemia

scientific article

Antineoplastic effect of mer-trichlorobisdimethylsulphoxideaminorutheniumIII against murine tumors: comparison with cisplatin and with ImH[RuIm2Cl4].

scientific article

Antineoplastic effects of egg-white lysozyme in mice bearing solid metastasizing tumors

scientific article published on 01 March 1986

Antitumor action of rhodium (I) and iridium (I) complexes

scientific article published in September 1978

Antitumor action of two rhodium and ruthenium complexes in comparison with cis-diamminedichloroplatinum(II).

scientific article published in August 1977

Antitumor activity of N-diazoacetyl derivatives of glycine and phenylalanine against P388 leukemia and B16 melanoma in mice

scientific article published on 01 January 1982

Antitumor and antimetastatic activity of the immunoadjuvant peptidoglycan monomer PGM in mice bearing MCa mammary carcinoma

scientific article published on 01 January 1984

Antitumor and antimetastatic effects of benzenoid triazenes in mice bearing lewis lung carcinoma

scientific article published on 01 January 1980

Antitumor effects of GANU and other nitrosourea derivatives against transplantable leukemias and solid tumors in mice

scientific article published on 01 January 1983

Antitumor effects of rhodium(I), iridium(I) and ruthenium(II) complexes in comparison with cis-dichlorodiammino platinum(II) in mice bearing Lewis lung carcinoma

scientific article published on 01 July 1983

Antitumour properties of dimethylsulphoxide ruthenium(II) complexes in the Lewis lung carcinoma system

scientific article published on 01 September 1989

Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir

scientific article published on August 2004

Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates

scientific article

Biochemical and biological characteristics of leucocyte proteinase inhibitors

scientific article published on 01 January 1982

Biological role of adduct formation of the ruthenium(III) complex NAMI-A with serum albumin and serum transferrin.

scientific article published on November 2003

Blood concentration and toxicity of the antimetastasis agent NAMI-A following repeated intravenous treatment in mice

scientific article published in November 2000

Blood levels of ruthenium following repeated treatments with the antimetastatic compound NAMI-A in healthy beagle dogs

scientific article published on 01 November 2000

CDK1 hyperphosphorylation maintenance drives the time-course of G2-M cell cycle arrest after short treatment with NAMI-A in Kb cells.

scientific article published on October 2012

Can peptides be orally-delivered in crustaceans? The case study of the Crustacean Hyperglycaemic Hormone in Procambarus clarkii

article

Chemical and Molecular Approach to Tumor Metastases.

scientific article

Chemical xenogenization of murine lymphoma cells with triazene derivatives: immunotoxicological studies

scientific article published on January 1984

Cocultures of metastatic and host immune cells: selective effects of NAMI-A for tumor cells

scientific article

Colorectal Cancer Metastases Settle in the Hepatic Microenvironment Through α5β1 Integrin.

scientific article

Comparison of the effects of the antimetastatic compound ImH[trans-RuCl4(DMSO)Im] (NAMI-A) on the arthritic rat and on MCa mammary carcinoma in mice

scientific article published on 01 January 1998

Cytofluorimetric analysis of gut-intraepithelial and mesenteric lymph node lymphocytes of tumour bearing mice fed with egg-white lysozyme

scientific article published on 01 January 1996

DTIC and its derivatives: cytotoxic or antimetastatic drugs?

scientific article published on January 1985

Development of a LC method for pharmaceutical quality control of the antimetastatic ruthenium complex NAMI-A.

scientific article published in February 2003

Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms

scientific article published on 10 April 2007

Distinct effects of dinuclear ruthenium(III) complexes on cell proliferation and on cell cycle regulation in human and murine tumor cell lines

scientific article published on 11 February 2003

Down-regulation of tumour gelatinase/inhibitor balance and preservation of tumour endothelium by an anti-metastatic ruthenium complex

scientific article published on 01 September 1996

Drug control of solid tumour metastases: a critical view.

scientific article

Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.

scientific article published in May 2003

Effects of DTIC, DM-COOK and ICRF-159 on the number of circulating Lewis lung carcinoma cells detected by flow cytometry

scientific article published on April 1984

Effects of L-(adamant-2-yl)glycyl-L-alanyl-d-isoglutamine on the antitumor action of cyclophosphamide, 5-fu, Cisplatin and dacarbazine on advanced carcinomas of the mouse

scientific article published on 01 August 1994

Effects of N-diazoacetyl-glycine amide on the pool of 5-phosphoribosyl 1-pyrophosphate in Ehrlich ascites tumour cells

scientific article published on 01 March 1976

Effects of NAMI-A and some related ruthenium complexes on cell viability after short exposure of tumor cells.

scientific article published in September 2000

Effects of Two Fullerene Derivatives on Monocytes and Macrophages.

scientific article

Effects of an inducer and an inhibitor of hepatic metabolism on the antitumor action of dimethyltriazenes

scientific article published on 01 January 1988

Effects of antimetastatic dimethyltriazenes in mice bearing Lewis lung carcinoma lines with different metastatic potential.

scientific article published on January 1984

Effects of antimetastatic, antiinvasive and cytotoxic agents on the growth and spread of transplantable leukemias in mice

scientific article published on January 1987

Effects of dimethyltriazenes combined with surgery and non-specific immunotherapy in mice bearing Lewis lung carcinoma lines

scientific article published on May 1985

Effects of isomeric aryldimethyltriazenes on lewis lung carcinoma growth and metastases in mice

scientific article published on 01 August 1983

Effects of lysozyme on spleen and lungs in mice with Lewis lung carcinoma

scientific article

Effects of p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt on leukemic infiltration of brain and liver in mice bearing P388 leukemia.

scientific article published on February 1984

Effects of postsurgical immunotherapy with PGM in mice bearing Lewis lung carcinoma treated with p-(3,3-dimethyl-1-triazeno) benzoic acid potassium salt

scientific article published on September 1985

Effects of ruthenium complexes on experimental tumors: irrelevance of cytotoxicity for metastasis inhibition

scientific article published on 01 March 1995

Effects of some ruthenium chelates on MCa mammary carcinoma and on TLX5 lymphoma in mice

scientific article published on 01 July 1993

Effects of the Ru(III) complexes [mer-RuCl3(DMSO)2Im]degrees and Na[trans-RuCl4(DMSO)Im] on solid mouse tumors

scientific article published on 01 February 1992

Effects of the ruthenium-based drug NAMI-A on the roles played by TGF-β1 in the metastatic process

scientific article published on 14 September 2015

Effects of trans-RuCl2(DMSO)4 on B16 melanoma in mice

scientific article published on 01 November 1989

Effects of two pyridinalalkyliminerhodium(I) complexes in mice bearing MCa mammary carcinoma

scientific article published on 01 January 1989

Efficacy of 5-FU Combined to Na[trans-RuCl(4)(DMSO)Im], A Novel Selective Antimetastatic Agent, on the Survival Time of Mice With P388 Leukemia, P388/DDP subline and MCa Mammary Carcinoma.

scientific article published on January 1995

Electrochemical measurements confirm the preferential bonding of the antimetastatic complex [ImH][RuCl(4)(DMSO)(Im)] (NAMI-A) with proteins and the weak interaction with nucleobases

scientific article

Evidence for host-mediated antitumor effects of lysozyme in mice bearing the MCa mammary carcinoma

scientific article published on November 1988

Features and full reversibility of the renal toxicity of the ruthenium-based drug NAMI-A in mice ⬇️

scientific article published on September 26, 2012

Free exchange across cells, and echistatin-sensitive membrane target for the metastasis inhibitor NAMI-A (imidazolium trans-imidazole dimethyl sulfoxide tetrachlororuthenate) on KB tumor cells.

scientific article

Half-sandwich Ru II[9]aneS3 complexes structurally similar to antitumor-active organometallic piano-stool compounds: preparation, structural characterization and in vitro cytotoxic activity

scientific article published on 9 January 2008

Hemostasis and mechanism of action of selective antimetastatic drugs in mice bearing Lewis lung carcinoma

scientific article published on July 1984

Human recombinant lysozyme downregulates advanced glycation endproduct-induced interleukin-6 production and release in an in-vitro model of human proximal tubular epithelial cells.

scientific article published on 4 February 2014

Hyaluronic-acid butyric esters as promising antineoplastic agents in human lung carcinoma: a preclinical study

scientific article published on August 2004

Identification and Characterization of a Novel Family of Cysteine-Rich Peptides (MgCRP-I) from Mytilus galloprovincialis

scientific article published on 21 July 2015

Immunogenic changes of murine lymphoma cells following in vitro treatment with aryl-triazene derivatives

scientific article published on 01 January 1984

Immunotherapy of lewis lung carcinoma with hydrosoluble peptidoglycan monomer (PGM)

scientific article published on 01 January 1983

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

scientific article published on June 2005

In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin

scientific article published in April 1999

In vitro down regulation of ICAM-1 and E-cadherin and in vivo reduction of lung metastases of TS/A adenocarcinoma by a lysozyme derivative.

scientific article published in October 1999

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model.

scientific article

Increase of tumour infiltrating lymphocytes in mice treated with antimetastatic doses of NAMI-A

scientific article published on 01 September 2000

Infiltration of liver and brain by tumor cells in leukemic mice: prevention by dimethyltriazenes and cyclophosphamide

scientific article published on December 1984

Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.

scientific article published in February 2002

Influence of the anionic ligands on the anticancer activity of Ru(II)-dmso complexes: Kinetics of aquation and in vitro cytotoxicity of new dicarboxylate compounds in comparison with their chloride precursors

scientific article published on 24 October 2007

Influence of the binding of reduced NAMI-A to human serum albumin on the pharmacokinetics and biological activity.

scientific article

Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.

scientific article published on 20 December 2005

Inhibition of adhesion, migration and of α5β1 integrin in the HCT-116 colorectal cancer cells treated with the ruthenium drug NAMI-A.

scientific article published on 27 February 2016

Inhibition of endothelial cell functions and of angiogenesis by the metastasis inhibitor NAMI-A.

scientific article

Inhibition of hepatocellular carcinomas in vitro and hepatic metastases in vivo in mice by the histone deacetylase inhibitor HA-But

scientific article published on July 2004

Inhibition of human pancreatic cell line MIA PaCa2 proliferation by HA-But, a hyaluronic butyric ester: a preliminary report

scientific article

Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation

scientific article published on December 2002

Inhibitory Effects of the Ruthenium Complex KP1019 in Models of Mammary Cancer Cell Migration and Invasion.

scientific article published on 17 September 2009

Intratumoral NAMI-A treatment triggers metastasis reduction, which correlates to CD44 regulation and tumor infiltrating lymphocyte recruitment

scientific article published on 9 April 2004

Investigation on the oxidative N-demethylation of aryl triazenes in vitro.

scientific article

Isolation of a murine metastatic cell line and preliminary test of sensitivity to the anti-metastasis agent NAMI-A.

scientific article

Kinetic investigation of the aqueous stability and antitumor activity of a hydrosoluble diaryltriazene, AVIS, related to the antimetastatic agent DM-COOK.

scientific article

Lack of In vitro cytotoxicity, associated to increased G(2)-M cell fraction and inhibition of matrigel invasion, may predict In vivo-selective antimetastasis activity of ruthenium complexes

scientific article published on 01 December 2000

Linking the future of anticancer metal-complexes to the therapy of tumour metastases

scientific article published on 26 March 2015

Lysosomal enzyme inhibitors and antimetastatic activity in the mouse

scientific article published on November 1977

Lysozyme induced recovery of the response to cona on mononuclear-cells harvested from mice bearing mca mammary-carcinoma

scientific article

Lysozyme-Induced Transcriptional Regulation of TNF-α Pathway Genes in Cells of the Monocyte Lineage ⬇️

scientific article published on 05 November 2019

Mechanism of the antileukemic effects of 1-p-carboxamidophenyl-3,3-dimethyltriazene and its in vitro metabolites.

scientific article published on November 1982

Mechanism of the antimetastatic action of N-diazoacetylglycinamide in mice bearing lewis lung carcinoma

scientific article published on 01 January 1980

Mechanism of the antimetastatic action of dimethyltriazenes

scientific article published on January 1979

Mechanism of the antineoplastic action of lysozyme: evidence for host mediated effects

scientific article

Metabolism and mechanism of the antileukemic action of isomeric aryldimethyltriazenes.

scientific article published on September 1982

Metal based drugs restyled and resumed

scientific article published in January 2007

Metal complexes of ruthenium: a potential class of selective anticancer drugs.

scientific article published on May 1991

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA ⬇️

scientific article published on March 3, 2011

Metal-based antitumour drugs in the post genomic era.

scientific article

Metal-based antitumour drugs in the post-genomic era: what comes next? ⬇️

scientific article published on July 4, 2011

Methodologic problems encountered in the assay of proteinases in Lewis lung carcinoma, a mouse metastasizing tumor

scientific article published on 01 October 1982

Microencapsulation of bioactive principles with an airless spray-gun suitable for processing high viscous solutions

scientific article published on 19 November 2013

Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry

scientific article published in May 1998

Modification of the growth of mca mammary-carcinoma of cba mouse by new adamantylpeptides

scientific article published on 01 April 1993

Modulation of the metastatic progression of breast cancer with an organometallic ruthenium compound.

scientific article

Molecular structure, solution chemistry and biological properties of the novel [ImH][trans-IrCl(4)(Im)(DMSO)], (I) and of the orange form of [(DMSO)(2)H][trans-IrCl(4)(DMSO)(2)], (II), complexes

scientific article published in May 2003

Mutagenic activity of the dacarbazine analog p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt in bacterial cells

scientific article published on May 1986

Na[trans-RuCl4(DMSO)Im], a metal complex of ruthenium with antimetastatic properties

scientific article published on 01 July 1992

Neutral proteinase inhibitors and antimetastatic effects in mice

scientific article published on April 1980

Observations on the antimetastatic action of lysozyme in mice bearing Lewis lung carcinoma

scientific article published on May 1991

Observations on the “in vitro” oxidative N-demethylation of 4-(3,3-dimetryl-1-triazeno)-imidazole-5-carboxamide (DIC, NSC 45388)

scientific article published on 01 February 1976

Oral poly(ethylene glycol)-conjugated human recombinant lysozyme control of lung metastases in mice

scientific article published in November 2008

Orally administered microencapsulated lysozyme downregulates serum AGE and reduces the severity of early-stage diabetic nephropathy

scientific article

Paracrine effects of IL-4 transfection on TS/A adenocarcinoma cells mediate reduced in vivo growth

scientific article published on January 1999

Pharmaceutical development of a parenteral lyophilized formulation of the antimetastatic ruthenium complex NAMI-A.

scientific article published in November 2002

Pharmacological Activities of Ruthenium Complexes Related to Their NO Scavenging Properties

scientific article published on 2 August 2016

Pharmacological Effects of the Ruthenium Complex NAMI-A Given Orally to CBA Mice With MCa Mammary Carcinoma.

scientific article published on January 2001

Pharmacological aspects and therapeutic applications of lysozymes

scientific article

Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex

scientific article published on May 1998

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

scientific article published on 25 October 2014

Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.

scientific article published in November 2002

Platinum(II) complexes with antitumoral/antiviral aromatic heterocycles: effect of glutathione upon in vitro cell growth inhibition

scientific article

Preclinical combination therapy of the investigational drug NAMI-A(+) with doxorubicin for mammary cancer

scientific article

Primary tumor growth and formation of spontaneous lung metastases in mice bearing Lewis carcinoma treated with proteinase inhibitors

scientific article published on 01 July 1984

Primary tumor, lung and kidney retention and antimetastasis effect of NAMI-A following different routes of administration

scientific article

Profiling the molecular mechanism of fullerene cytotoxicity on tumor cells by RNA-seq

scientific article published on 12 October 2013

Prophylactic antimetastatic treatment with aryldimethyltriazenes as adjuvants to surgical tumor removal in mice bearing Lewis lung carcinoma.

scientific article published on January 1982

Proteinases and proteinase inhibition by cytotoxic and antimetastatic drugs in transplantable solid metastasizing tumors in mice

scientific article published in July 1985

RNA-seq analysis of the whole transcriptome of MDA-MB-231 mammary carcinoma cells exposed to the antimetastatic drug NAMI-A.

scientific article published on 4 September 2015

Reduction of B16 melanoma metastases by oral administration of egg-white lysozyme

scientific article published on 01 January 1989

Reduction of Lung Metastases by Na[trans-RuCl(4)(DMSO)Im] is not Coupled With the Induction of Chemical Xenogenization.

scientific article published on January 1996

Reduction of MCa mammary carcinoma in mice fed with egg-white lysozyme

scientific article published on 01 September 1990

Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.

scientific article published on February 2004

Role of host responses in the drug treatment of metastasis

article

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs ⬇️

scientific article published on August 21, 2011

Ruthenium antimetastatic agents

scientific article

Ruthenium(III) dimethyl sulfoxide pyridinehydroxamic acid complexes as potential antimetastatic agents: synthesis, characterisation and in vitro pharmacological evaluation

scientific article published on May 2008

Ruthenium-based NAMI-A type complexes with in vivo selective metastasis reduction and in vitro invasion inhibition unrelated to cell cytotoxicity.

scientific article published on December 2002

Ruthenium-based compounds and tumour growth control (review).

scientific article published in August 2000

Ruthenium-porphyrin conjugates with cytotoxic and phototoxic antitumor activity

scientific article

Selective antimetastatic drugs (review).

scientific article published on January 1981

Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma.

scientific article published on June 1981

Solution, solid state and biological characterization of ruthenium(III)-DMSO complexes with purine base derivatives

scientific article

Some further characteristics of endogenous proteinase inhibitors

scientific article published on 01 January 1982

Stimulation of GALT and activation of mesenteric lymph node lymphocytes by a modified lysozyme in CBA mice with MCa mammary carcinoma

scientific article published on 01 November 1996

Structure-dependent in vitro cytotoxicity of the isomeric complexes [Ru(L)2Cl2] (L= o-tolylazopyridine and 4-methyl-2-phenylazopyridine) in comparison to [Ru(azpy)2Cl2].

scientific article published on 19 March 2004

Study of a potential drug delivery system based on carbon nanoparticles: effects of fullerene derivatives in MCF7 mammary carcinoma cells

Synthesis and antitumor activity of hydrosoluble analogs of p-(3,3-dimethyl-1-triazeno) benzoic acid potassium salt

scientific article published on 01 November 1991

Synthesis and chemical-pharmacological characterization of the antimetastatic NAMI-A-type Ru(III) complexes (Hdmtp)[trans-RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7-dimethyl[1,2,4]triazolo[1

scientific article published in February 2004

Synthesis of l-Aryl-3-formyl-3-methyltriazenes, Potential Metabolites of l-Ary1-3,3-dimethyltriazenes

scientific article published on 01 September 1980

Synthesis, Characterization, and in Vitro Evaluation of Novel Ruthenium(II) η6-Arene Imidazole Complexes

scientific article published on 01 September 2006

Synthesis, catalytic properties and biological activity of new water soluble ruthenium cyclopentadienyl PTA complexes [(C5R5)RuCl(PTA)2] (R = H, Me; PTA = 1,3,5-triaza-7-phosphaadamantane).

scientific article published on January 2003

Synthesis, characterization and biological activity of copper complexes with pyridoxal thiosemicarbazone derivatives. X-ray crystal structure of three dimeric complexes

scientific article published on February 2004

Synthetic thymic fraction 5: effects of high dose administration on circulating lymphocytes in patients

scientific article published on April 1996

TGFbeta1 regulation and collagen-release-independent connective tissue re-modelling by the ruthenium complex NAMI-A in solid tumours

scientific article published on October 2004

Targeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs ⬇️

scientific article published on May 22, 2012

The Differential Distribution of RAPTA-T in Non-Invasive and Invasive Breast Cancer Cells Correlates with Its Anti-Invasive and Anti-Metastatic Effects.

scientific article published on 29 August 2017

The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway

scientific article published on July 2002

The antimetastatic drug NAMI-A potentiates the phenylephrine-induced contraction of aortic smooth muscle cells and induces a transient increase in systolic blood pressure.

scientific article

The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation

scientific article

The role of cisplatin and NAMI-A plasma-protein interactions in relation to combination therapy.

scientific article published in July 2006

Treatment of metastases of solid mouse tumours by NAMI-A: comparison with cisplatin, cyclophosphamide and dacarbazine

scientific article published on 01 March 1999

Treatment of residual metastases with Na[trans-RuCl4 (DMSO)lm] and ruthenium uptake by tumor cells

scientific article published on 01 August 1996

Tumor cell metastasis and surface neutral proteinase: effects of antimetastatic and antitumor drugs.

scientific article

Tumour cell uptake G2-M accumulation and cytotoxicity of NAMI-A on TS/A adenocarcinoma cells

scientific article

Tumour cell uptake of the metastasis inhibitor ruthenium complex NAMI-A and its in vitro effects on KB cells

scientific article published on 12 September 2002

Tuning the hydrophobicity of ruthenium(II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy

scientific article published on 26 September 2007

Validated method for the determination of the novel organo-ruthenium anticancer drug NAMI-A in human biological fluids by Zeeman atomic absorption spectrometry

scientific article

[The clinical risk management: an initial experience of incident reporting in a surgical department]

scientific article published on 01 July 2010

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