Search filters

List of works by Lilia Alberghina

A cell sizer network involving Cln3 and Far1 controls entrance into S phase in the mitotic cycle of budding yeast.

scientific article published on November 2004

A comparative study of Whi5 and retinoblastoma proteins: from sequence and structure analysis to intracellular networks.

scientific article

A critical review of multiscale modeling for predictive understanding of cancer cell metabolism

scientific article published in December 2024

A double flow cytometric tag allows tracking of the dynamics of cell cycle progression of newborn Saccharomyces cerevisiae cells during balanced exponential growth

scientific article published in September 1995

A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect

scientific article published on 28 September 2017

A model for the regulation of growth in mammalian cells

scientific article published on 01 December 1975

A new nerve growth factor-mimetic peptide active on neuropathic pain in rats

scientific article published in March 2008

A surface-activated chemical ionization approach allows quantitative phosphorylation analysis of the cyclin-dependent kinase inhibitor Sic1 phosphorylated on Ser201.

scientific article

A systems biology road map for the discovery of drugs targeting cancer cell metabolism.

scientific article published on January 2014

Acquired glucose sensitivity of k-ras transformed fibroblasts.

scientific article

Alteration of cell population structure due to cell lysis inSaccharomyces cerevisiae cells overexpressing theGAL4 gene

article

An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes

scientific article

An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides

scientific article published on 13 January 2007

Analysis of a cell cycle model for Escherichia coli

scientific article published in June 1980

Analysis of the secondary structure of the catalytic domain of mouse Ras exchange factor CDC25Mm

scientific article published on 01 April 1998

Astrocyte-neuron interplay in maladaptive plasticity

scientific article published on 06 February 2014

Astrocytes and Microglia-Mediated Immune Response in Maladaptive Plasticity is Differently Modulated by NGF in the Ventral Horn of the Spinal Cord Following Peripheral Nerve Injury

scientific article

Astrogliosis as a therapeutic target for neurodegenerative diseases.

scientific article published on 20 January 2014

BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury

scientific article published on 18 May 2011

Bombesin stimulates a high affinity GTPase activity in membranes of Swiss 3T3 fibroblasts

scientific article published on May 1991

CK2 activity is modulated by growth rate in Saccharomyces cerevisiae

scientific article published on 17 June 2010

CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1

scientific article published in 2005

Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling

scientific article

Catalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577

scientific article

Cell cycle analysis in a human cell line (EUE cells)

scientific article published on 01 May 1982

Cell cycle modelling

scientific article published in January 1986

Cell size at S phase initiation: an emergent property of the G1/S network

scientific article

Cell size modulation by CDC25 and RAS2 genes in Saccharomyces cerevisiae.

scientific article published on June 1989

Change of the cytochrome oxidase level during exponential growth in Neurospora crassa ⬇️

scientific article published on August 15, 1975

Changes in the protein synthesis pattern during a nutritional shift-down transition in Saccharomyces cerevisiae

scientific article published on 01 April 1990

Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).

scientific article

Characterization of the Candida rugosa lipase system and overexpression of the lip1 isoenzyme in a non-conventional yeast

scientific article published on 01 June 1998

Characterization of the tyrosine phosphorylation of calpactin I (annexin II) induced by platelet-derived growth factor.

scientific article published on September 1991

Chromosome Separation and Exit from Mitosis in Budding Yeast: Dependence on Growth Revealed by cAMP-Mediated Inhibition

scientific article published on 01 August 1999

Cloning and analysis of Candida cylindracea lipase sequences.

scientific article published in February 1993

Compaction properties of an intrinsically disordered protein: Sic1 and its kinase-inhibitor domain

scientific article published in May 2011

Comparative analysis of the molecular mechanisms controlling the initiation of chromosomal DNA replication in yeast and in mammalian cells.

scientific article published on 22 September 2011

Comparing Alzheimer's and Parkinson's diseases networks using graph communities structure

scientific article

Computational strategies for a system-level understanding of metabolism

scientific article

Control of the yeast cell cycle by protein synthesis.

scientific article

Copy number modulation in an autoselection system for stable plasmid maintenance in Saccharomyces cerevisiae

scientific article published in November 1993

Cross-talk between cell cycle induction and mitochondrial dysfunction during oxidative stress and nerve growth factor withdrawal in differentiated PC12 cells

scientific article published on 06 May 2011

Design and realization of a tailor-made enzyme to modify the molecular recognition of 2-arylpropionic esters by Candida rugosa lipase

scientific article published on 01 November 2000

Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid

article

Different types of cell death in organismal aging and longevity: state of the art and possible systems biology approach

scientific article published on January 2008

Differentiation by nerve growth factor (NGF) involves mechanisms of crosstalk between energy homeostasis and mitochondrial remodeling.

scientific article published on 9 March 2018

Dissociation of the ligand and dephosphorylation of the platelet-derived growth factor receptor

scientific article published on 01 June 1988

Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study.

scientific article published on 07 July 2016

Dynamics of cellular growth ⬇️

scientific article published on July 1, 1975

Dynamics of the cell cycle in mammalian cells ⬇️

scientific article published on December 21, 1977

Effect of the different dimeric forms of the platelet-derived growth factor on cellular responses in mouse Swiss 3T3 fibroblasts

scientific article published on September 1989

Effect of the growth conditions on the expression of cell-surface-associated platelet-derived growth factor receptors in mouse fibroblasts

scientific article published on October 1988

Electrospray ionization-mass spectrometry conformational analysis of isolated domains of an intrinsically disordered protein.

scientific article

Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK.

scientific article published on 2 April 2015

Enhanced expression of heterologous proteins by the use of a superinducible vector in budding yeast.

scientific article published in February 1992

Evolutionary conservation of genomic sequences related to the GGP1 gene encoding a yeast GPI-anchored glycoprotein

article

Expression of cloned Saccharomyces diastaticus glucoamylase under natural and inducible promoters.

scientific article

Expression of transforming K-Ras oncogene affects mitochondrial function and morphology in mouse fibroblasts.

scientific article published on 3 August 2006

Flow cytometry and cell cycle kinetics in continuous and fed-batch fermentations of budding yeast.

scientific article published in July 1991

From cancer metabolism to new biomarkers and drug targets

scientific article published on 23 July 2011

Glucose metabolism and cell size in continuous cultures of Saccharomyces cerevisiae

scientific article published in December 2003

Glucose modulation of cell size in yeast.

scientific article

Glucose signaling-mediated coordination of cell growth and cell cycle in Saccharomyces cerevisiae.

scientific article published on 21 June 2010

Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response

scientific article published on 18 July 2013

Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts

scientific article

Heterologous gene expression in continuous cultures of budding yeast.

scientific article published in February 1991

Heterologous production of five Hepatitis C virus-derived antigens in three Saccharomyces cerevisiae host strains.

scientific article published on 21 July 2005

Identification of different daughter and parent subpopulations in an asynchronously growing Saccharomyces cerevisiae population

scientific article published on 01 March 1997

Immunochemical studies of ribosomal proteins using passive hemagglutination techniques

scientific article published on 01 December 1969

Immunological cross-reactivity of fungal and yeast plasma membrane H+-ATPase.

scientific article published in September 1986

In CK2 inactivated cells the cyclin dependent kinase inhibitor Sic1 is involved in cell-cycle arrest before the onset of S phase.

scientific article

In Saccharomyces cerevisiae, protein secretion into the growth medium depends on environmental factors.

scientific article

In vitro interaction between Saccharomyces cerevisiae CDC25 and RAS2 proteins

scientific article published on 01 July 1992

In vivo phosphorylation and dephosphorylation of the platelet-derived growth factor receptor studied by immunoblot analysis with phosphotyrosine antibodies

scientific article (publication date: 19 March 1986)

Integration of single-cell RNA-seq data into population models to characterize cancer metabolism

scientific article published on 28 February 2019

Integrative transcriptional analysis between human and mouse cancer cells provides a common set of transformation associated genes

scientific article published on 29 June 2011

Intrathecal NGF Administration Reduces Reactive Astrocytosis and Changes Neurotrophin Receptors Expression Pattern in a Rat Model of Neuropathic Pain

scientific article published on 08 July 2009

Involvement of a cell size control mechanism in the induction and maintenance of oscillations in continuous cultures of budding yeast

scientific article published in August 1990

Involvement of the yeast metacaspase Yca1 in ubp10Delta-programmed cell death

scientific article published in November 2004

Lactose/whey utilization and ethanol production by transformed Saccharomyces cerevisiae cells

scientific article published on 01 April 1992

Level and Turnover of Polyadenylate-Containing Ribonucleic Acid in Neurospora crassa in Different Steady States of Growth ⬇️

scientific article published on August 15, 1979

Mathematical modelling of DNA replication reveals a trade-off between coherence of origin activation and robustness against rereplication

scientific article

Microbial analysis at the single-cell level

scientific article published on 01 September 2000

Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells

scientific article published on 18 November 2009

Modulation of Matrix Metalloproteinases Activity in the Ventral Horn of the Spinal Cord Re-stores Neuroglial Synaptic Homeostasis and Neurotrophic Support following Peripheral Nerve Injury

scientific article

Molecular cloning and regulation of the expression of the MET2 gene of Saccharomyces cerevisiae.

scientific article

Molecular evolution of the neurotrophin family members and their Trk receptors.

scientific article published on 9 February 2007

Mutants provide evidence of the importance of glycosydic chains in the activation of lipase 1 from Candida rugosa.

scientific article

Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins.

scientific article published on December 1998

Mutations in the "lid" region affect chain length specificity and thermostability of a Pseudomonas fragi lipase

scientific article published in April 2005

Mutations of the CK2 phosphorylation site of Sic1 affect cell size and S-Cdk kinase activity in Saccharomyces cerevisiae.

scientific article

Networks and circuits in cell regulation.

scientific article published on 10 May 2010

Neuroprotection by Cocktails of Dietary Antioxidants under Conditions of Nerve Growth Factor Deprivation

scientific article published on 8 July 2015

New Insights into the Connection Between Histone Deacetylases, Cell Metabolism, and Cancer.

scientific article published on 06 March 2014

Nicotinamide, Nicotinamide Riboside and Nicotinic Acid-Emerging Roles in Replicative and Chronological Aging in Yeast

scientific article published on 15 April 2020

Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells.

scientific article published on 18 May 2011

Nutritional limitation sensitizes mammalian cells to GSK-3β inhibitors and leads to growth impairment

scientific article published on April 2011

On enzyme inhibition by oxidized chlorogenic acid

scientific article published on 01 January 1964

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth

scientific article

Oncogenic K-ras expression is associated with derangement of the cAMP/PKA pathway and forskolin-reversible alterations of mitochondrial dynamics and respiration ⬇️

scientific article published on March 12, 2012

Order propensity of an intrinsically disordered protein, the cyclin-dependent-kinase inhibitor Sic1

scientific article published on August 2009

Oscillations in continuous cultures of budding yeast: a segregated parameter analysis.

scientific article published on August 1988

Overexpression of Far1, a cyclin-dependent kinase inhibitor, induces a large transcriptional reprogramming in which RNA synthesis senses Far1 in a Sfp1-mediated way

scientific article published on 21 September 2011

Overexpression of the CDC25 gene, an upstream element of the ras/adenylyl cyclase pathway in Saccharomyces cerevisiae, allows immunological identification and characterization of its gene product

article

Posttranscriptional regulation of the expression of MET2 gene of Saccharomyces cerevisiae

article

Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis

scientific article

Protein kinase CK2 holoenzyme promotes start-specific transcription in Saccharomyces cerevisiae.

scientific article published on 19 July 2013

Proteomic analysis of a nutritional shift-up in Saccharomyces cerevisiae identifies Gvp36 as a BAR-containing protein involved in vesicular traffic and nutritional adaptation.

scientific article

Proteomics and systems biology to tackle biological complexity: Yeast as a case study

scientific article published in December 2010

Purinergic Modulation of Spinal Neuroglial Maladaptive Plasticity Following Peripheral Nerve Injury

scientific article published on 29 October 2014

Quantitative flow cytometry: analysis of protein distributions in budding yeast. A mini-review.

scientific article

ROS networks: designs, aging, Parkinson's disease and precision therapies

scientific article published on 26 October 2020

Rapamycin-mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in Saccharomyces cerevisiae

scientific article published on 01 March 2007

Ras-dependent carbon metabolism and transformation in mouse fibroblasts

scientific article published on 10 April 2006

Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor.

scientific article published on 25 November 2010

Real-time flow cytometric quantification of GFP expression and Gfp-fluorescence generation in Saccharomyces cerevisiae

scientific article published on 01 September 2000

Recombinant human nerve growth factor with a marked activity in vitro and in vivo.

scientific article

Redox control of glutamine utilization in cancer

scientific article

Reduction of ribosome activity and synthesis of stable RNA in Neurospora crassa

scientific article published on 01 December 1980

Regulation of hSos1 activity is a system-level property generated by its multi-domain structure.

scientific article published on 6 August 2011

Relating growth dynamics and glucoamylase excretion of individual Saccharomyces cerevisiae cells

article

Remodelling of supraspinal neuroglial network in neuropathic pain is featured by a reactive gliosis of the nociceptive amygdala.

scientific article

Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast

scientific article published on 16 June 2016

Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease

scientific article published on 28 April 2016

SFP1 is involved in cell size modulation in respiro-fermentative growth conditions.

scientific article

Sequence of the lid affects activity and specificity of Candida rugosa lipase isoenzymes ⬇️

scientific article published on October 1, 2003

Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells

scientific article published on 6 June 2006

Sir2-dependent asymmetric segregation of damaged proteins in ubp10 null mutants is independent of genomic silencing

scientific article published on 04 March 2010

Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast.

scientific article published in June 2010

Snf1/AMPK promotes SBF and MBF-dependent transcription in budding yeast.

scientific article

Strategies for structuring interdisciplinary education in Systems Biology: an European perspective.

scientific article

Subcellular localization of the cyclin dependent kinase inhibitor Sic1 is modulated by the carbon source in budding yeast.

scientific article

Systems Biology for biotechnological innovation

article

Systems biology for biomedical innovation

article

Systems biology of the cell cycle of Saccharomyces cerevisiae: From network mining to system-level properties

scientific article published on 22 May 2009

Targeting reactive astrogliosis by novel biotechnological strategies ⬇️

scientific article published on July 5, 2011

The Minimal Active Domain of the Mouse Ras Exchange Factor CDC25Mm

scientific article published on 01 January 1995

The Warburg Effect Explained: Integration of Enhanced Glycolysis with Heterogeneous Mitochondria to Promote Cancer Cell Proliferation

scientific article published on 31 October 2023

The acquisition of competence as a possible source of cell cycle variability in mouse fibroblasts

scientific article published on 01 October 1981

The biogenesis of mitochondria in Neurospora crassa: Ultrastructural changes induced by nutrients

scientific article published on 01 March 1974

The cell cycle modulated glycoprotein GP115 is one of the major yeast proteins containing glycosylphosphatidylinositol

scientific article published in May 1990

The cold-active lipase ofPseudomonas fragi

scientific article published on 01 July 2002

The histone deubiquitinating enzyme Ubp10 is involved in rDNA locus control in Saccharomyces cerevisiae by affecting Sir2p association

scientific article published on 8 October 2006

The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin

scientific article

The isolated catalytic hairpin of the Ras-specific guanine nucleotide exchange factor Cdc25Mm retains nucleotide dissociation activity but has impaired nucleotide exchange activity.

scientific article published on 28 November 2005

The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration

scientific article published on 30 October 2006

The overexpression of the 3′ terminal region of the CDC25 gene of Saccharomyces cerevisiae causes growth inhibition and alteration of purine nucleotides pools

article

The sequence of 8.8 kb of yeast chromosome III cloned in lambda PM3270 contains an unusual long ORF (YCR601).

scientific article published on August 1991

The transcription factor Swi4 is target for PKA regulation of cell size at the G1 to S transition in Saccharomyces cerevisiae

scientific article published on 5 June 2015

The yeast Zygosaccharomyces bailii: a new host for heterologous protein production, secretion and for metabolic engineering applications

scientific article published in January 2004

The yeast cyclin-dependent kinase inhibitor Sic1 and mammalian p27Kip1 are functional homologues with a structurally conserved inhibitory domain

scientific article

Timing control in regulatory networks by multisite protein modifications

scientific article published on 23 September 2010

Towards a blueprint of the cell cycle

scientific article published on 01 March 2001

Transcript accumulation of the GGP1 gene, encoding a yeast GPI-anchored glycoprotein, is inhibited during arrest in the G1 phase and during sporulation

article

Transcriptional profiling of ubp10 null mutant reveals altered subtelomeric gene expression and insurgence of oxidative stress response.

scientific article published on 17 November 2003

Transcriptomics and Metabolomics Integration Reveals Redox-Dependent Metabolic Rewiring in Breast Cancer Cells

scientific article published in 2021

Translational regulation of the expression of zein cloned in yeast under an inducible GAL promoter

scientific article published on 01 July 1987

Unscrambling thermal stability and temperature adaptation in evolved variants of a cold-active lipase

scientific article

Whi5 phosphorylation embedded in the G1/S network dynamically controls critical cell size and cell fate.

scientific article

Zooming-in on cancer metabolic rewiring with tissue specific constraint-based models

scientific article published on 14 March 2016

[14] Cloning, sequencing, and expression of Candida rugosa lipases

scientific article published on 01 January 1997

cAMP-mediated increase in the critical cell size required for the G1 to S transition in Saccharomyces cerevisiae

scientific article published in August 1992

Paulina is supported by:

About Paulina

Help