List of works by Francesca Spadaro

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28.

scientific article published on 14 March 2018

Activation of Phosphatidylcholine-Specific Phospholipase C in Breast and Ovarian Cancer: Impact on MRS-Detected Choline Metabolic Profile and Perspectives for Targeted Therapy

scientific article published on 2 August 2016

Alterations of choline phospholipid metabolism in ovarian tumor progression

scientific article published on October 2005

Apicidin and docetaxel combination treatment drives CTCFL expression and HMGB1 release acting as potential antitumor immune response inducers in metastatic breast cancer cells.

scientific article

Caveolin-1 tumor-promoting role in human melanoma

scientific article

Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis

scientific article

Dendritic cells derived from BCG-infected precursors induce Th2-like immune response

scientific article published on 7 July 2004

Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells

scientific article published on 01 November 2002

Endogenous CCL2 (monocyte chemotactic protein-1) modulates human immunodeficiency virus type-1 replication and affects cytoskeleton organization in human monocyte-derived macrophages

scientific article published on 12 June 2003

Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma.

scientific article published on 2 November 2015

Exogenous HIV-1 Nef upsets the IFN-γ-induced impairment of human intestinal epithelial integrity

scientific article (publication date: 2011)

Expression and role of phosphatidylcholine-specific phospholipase C in human NK and T lymphocyte subsets

scientific article published on 01 December 2006

Functional role of phosphatidylcholine-specific phospholipase C in regulating CD16 membrane expression in natural killer cells

scientific article published on 01 October 2007

HIV-1 Nef triggers Vav-mediated signaling pathway leading to functional and morphological differentiation of dendritic cells

scientific article published in November 2003

Human melanoma cells express FGFR/Src/Rho signaling that entails an adhesion-independent caveolin-1 membrane association

scientific article published on 25 May 2011

IFN-α enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing.

scientific article published on 19 December 2011

IL-2 induces expression and secretion of IFN-γ in murine peritoneal macrophages

scientific article published on 10 June 2005

IL-33 Promotes CD11b/CD18-Mediated Adhesion of Eosinophils to Cancer Cells and Synapse-Polarized Degranulation Leading to Tumor Cell Killing

scientific article published on 26 October 2019

IRF-8 controls melanoma progression by regulating the cross talk between cancer and immune cells within the tumor microenvironment.

scientific article published on December 2012

Immune surveillance properties of human NK cell-derived exosomes.

scientific article published on 17 August 2012

Inhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells

scientific article

Interferon-α-conditioned human monocytes combine a Th1-orienting attitude with the induction of autologous Th17 responses: role of IL-23 and IL-12.

scientific article

Key Players in Choline Metabolic Reprograming in Triple-Negative Breast Cancer

scientific article

LOX-1 as a natural IFN- -mediated signal for apoptotic cell uptake and antigen presentation in dendritic cells

scientific article published on 15 December 2009

Lenalidomide improves the therapeutic effect of an interferon-α-dendritic cell-based lymphoma vaccine

scientific article published on 16 October 2019

Macrophages and Phospholipases at the Intersection between Inflammation and the Pathogenesis of HIV-1 Infection

scientific article published on 29 June 2017

NK Cell Activation in the Antitumor Response Induced by IFN-α Dendritic Cells Loaded with Apoptotic Cells from Follicular Lymphoma Patients.

scientific article published on 29 June 2016

Nuclear phosphoinositide-specific phospholipase C β1 controls cytoplasmic CCL2 mRNA levels in HIV-1 gp120-stimulated primary human macrophages

scientific article

Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells

scientific article published in August 2008

Phosphatidylcholine-specific phospholipase C activation is required for CCR5-dependent, NF-kB-driven CCL2 secretion elicited in response to HIV-1 gp120 in human primary macrophages

scientific article

Phosphatidylcholine-specific phospholipase C inhibition reduces HER2-overexpression, cell proliferation and in vivo tumor growth in a highly tumorigenic ovarian cancer model

scientific article

Phospholipases: at the crossroads of the immune system and the pathogenesis of HIV-1 infection

scientific article published on November 2016

Triacsin C inhibits the formation of 1H NMR-visible mobile lipids and lipid bodies in HuT 78 apoptotic cells ⬇️

scientific article published on October 20, 2003

Type I IFNs control antigen retention and survival of CD8α(+) dendritic cells after uptake of tumor apoptotic cells leading to cross-priming

scientific article published on 25 March 2011

hMENA is a key regulator in endothelin-1/β-arrestin1-induced invadopodial function and metastatic process.

scientific article published on 8 February 2018

β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling.

scientific article

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