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List of works by Carmen Vale

13-Desmethyl spirolide-C is neuroprotective and reduces intracellular Aβ and hyperphosphorylated tau in vitro

scientific article published on 30 August 2011

A comparative study of the effect of ciguatoxins on voltage-dependent Na+ and K+ channels in cerebellar neurons

scientific article published on 21 March 2011

Afferent regulation of inhibitory synaptic transmission in the developing auditory midbrain.

scientific article published in March 2000

Allosteric interactions between gamma-aminobutyric acid, benzodiazepine and picrotoxinin binding sites in primary cultures of cerebellar granule cells. Differential effects induced by gamma- and delta-hexachlorocyclohexane

scientific article published in January 1997

Auditory nerve input is not an absolute requirement for the expression, distribution and calcium permeability of AMPA receptors in the adult rat ventral cochlear nucleus.

scientific article published on 2 February 2007

Autumnalamide, a prenylated cyclic peptide from the cyanobacterium Phormidium autumnale, acts on SH-SY5Y cells at the mitochondrial level

scientific article published on 29 September 2014

Benefit of 13-desmethyl spirolide C treatment in triple transgenic mouse model of Alzheimer disease: beta-amyloid and neuronal markers improvement.

scientific article published in March 2013

Calcium oscillations induced by gambierol in cerebellar granule cells.

scientific article

Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons.

scientific article published on 08 October 2009

Chronic In Vivo Effects of Repeated Exposure to Low Oral Doses of Tetrodotoxin: Preliminary Evidence of Nephrotoxicity and Cardiotoxicity

scientific article published on 06 February 2019

Chronic ciguatoxin treatment induces synaptic scaling through voltage gated sodium channels in cortical neurons

scientific article published on 19 May 2015

Cytotoxic action of lindane in cerebellar granule neurons is mediated by interaction with inducible GABA(B) receptors

scientific article published in May 1998

Cytotoxic action of lindane in neocortical GABAergic neurons is primarily mediated by interaction with flunitrazepam-sensitive GABA(A) receptors

scientific article published in May 1998

Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: involvement of the c-Jun N-terminal kinase

scientific article published on 01 October 2008

Deafness disrupts chloride transporter function and inhibitory synaptic transmission.

scientific article published in August 2003

Design and synthesis of skeletal analogues of gambierol: attenuation of amyloid-β and tau pathology with voltage-gated potassium channel and N-methyl-D-aspartate receptor implications

scientific article

Detection of Cyclic Imine Toxins in Dietary Supplements of Green Lipped Mussels (Perna canaliculus) and in Shellfish Mytilus chilensis

scientific article published on 24 September 2020

Developmental regulation and adult maintenance of potassium channel proteins (Kv 1.1 and Kv 1.2) in the cochlear nucleus of the rat.

scientific article published in September 2005

Differential effects of ciguatoxin and maitotoxin in primary cultures of cortical neurons

scientific article published on 15 July 2014

Differential effects of crambescins and crambescidin 816 in voltage-gated sodium, potassium and calcium channels in neurons.

scientific article

Effect of gambierol and its tetracyclic and heptacyclic analogues in cultured cerebellar neurons: a structure-activity relationships study

scientific article published on 29 August 2012

Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study

scientific article

Evaluation of various pH and temperature conditions on the stability of azaspiracids and their importance in preparative isolation and toxicological studies

scientific article

Expression and developmental regulation of the K+-Cl- cotransporter KCC2 in the cochlear nucleus.

scientific article published in August 2005

In Vitro Effects of Chronic Spirolide Treatment on Human Neuronal Stem Cell Differentiation and Cholinergic System Development

scientific article published on 14 March 2018

In Vivo Evaluation of the Chronic Oral Toxicity of the Marine Toxin Palytoxin

scientific article published on 30 July 2020

In vitro and in vivo evaluation of paralytic shellfish poisoning toxin potency and the influence of the pH of extraction.

scientific article

Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins.

scientific article published on 24 October 2008

Mitogen-activated protein kinases regulate palytoxin-induced calcium influx and cytotoxicity in cultured neurons

scientific article published on 16 July 2007

Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin.

scientific article published in June 2006

Modulatory effect of Palicourea coriacea (Rubiaceae) against damage induced by doxorubicin in somatic cells of Drosophila melanogaster

scientific article published on 15 June 2010

Oral Chronic Toxicity of the Safe Tetrodotoxin Dose Proposed by the European Food Safety Authority and Its Additive Effect with Saxitoxin

scientific article published on 09 May 2020

Potassium currents inhibition by gambierol analogs prevents human T lymphocyte activation

scientific article published on 26 August 2014

Profile for amyloid-beta and tau expression in primary cortical cultures from 3xTg-AD mice

scientific article published on 27 November 2009

Reevaluation of the acute toxicity of palytoxin in mice: Determination of lethal dose 50 (LD50) and No-observed-adverse-effect level (NOAEL)

scientific article published on 24 January 2020

Serotonin involvement in okadaic acid-induced diarrhoea in vivo

scientific article published on 20 June 2021

Structure Elucidation and Biological Evaluation of Maitotoxin-3, a Homologue of Gambierone, from

scientific article published on 01 February 2019

Synergistic Effect of Transient Receptor Potential Antagonist and Amiloride against Maitotoxin Induced Calcium Increase and Cytotoxicity in Human Neuronal Stem Cells

scientific article published on 16 May 2018

Synthetic ciguatoxin CTX 3C induces a rapid imbalance in neuronal excitability

scientific article published on 19 May 2015

The Cholinergic Antagonist Gymnodimine Improves Aβ and Tau Neuropathology in an in Vitro Model of Alzheimer Disease

article

The Marine Guanidine Alkaloid Crambescidin 816 Induces Calcium Influx and Cytotoxicity in Primary Cultures of Cortical Neurons through Glutamate Receptors

scientific article published on 4 April 2017

The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1.

scientific article published in January 2007

The effect of bilateral deafness on excitatory and inhibitory synaptic strength in the inferior colliculus

scientific article

The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with GABA(A) and glycine-gated chloride channels in primary cultures of cerebellar granule cells

scientific article

Transcriptomic Analysis of Ciguatoxin-Induced Changes in Gene Expression in Primary Cultures of Mice Cortical Neurons.

scientific article

Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and β-amyloid pathology.

scientific article published on 08 April 2013

Unilateral cochlear ablation produces greater loss of inhibition in the contralateral inferior colliculus

scientific article published in October 2004