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List of works by Michael Freeley

A high-content analysis toolbox permits dissection of diverse signaling pathways for T lymphocyte polarization.

scientific article

Advances in siRNA delivery to T-cells: potential clinical applications for inflammatory disease, cancer and infection

scientific article published on October 2013

Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression.

scientific article published on 22 June 2016

Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.

scientific article

CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes.

scientific article

Candidate Gene Knockdown in Celiac Disease

article

Current postgraduate training programs and online courses in precision medicine

scientific article published on 07 January 2020

Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.

scientific article published on 15 June 2016

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion

scientific article published on 2 May 2011

L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes

scientific article published on 11 May 2012

LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3β Signaling-Dependent Notch Pathway

scientific article published on 20 May 2016

Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.

scientific article published on 3 August 2007

Microdamage: a cell transducing mechanism based on ruptured osteocyte processes

scientific article published on 19 August 2005

Phosphorylation of Rab5a protein by protein kinase Cϵ is crucial for T-cell migration.

scientific article

Protein kinase C delta is a substrate of tissue transglutaminase and a novel autoantigen in coeliac disease ⬇️

scientific article published on January 26, 2013

Protein kinase C: a regulator of cytoskeleton remodelling and T-cell migration.

scientific article

RNAi Screening with Self-Delivering, Synthetic siRNAs for Identification of Genes That Regulate Primary Human T Cell Migration.

scientific article published on 29 May 2015

Regulating the Regulator: Phosphorylation of PKC θ in T Cells

scientific article published on August 2012

Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites.

scientific article published on 12 October 2010

Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes.

scientific article published in August 2005

The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration

scientific article published in February 2006

The two hit hypothesis: an improved method for siRNA-mediated gene silencing in stimulated primary human T cells

scientific article published on 27 August 2013

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