List of works - Saverio Tardito

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

scientific article

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

scientific article published on 20 October 2017

Cancer metabolism at a glance

scientific article published in September 2016

Cell Culture Medium Formulation and Its Implications in Cancer Metabolism

scientific article published on 29 May 2019

Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells.

scientific article published on 31 March 2011

Copper compounds in anticancer strategies

scientific article published in January 2009

Copper-dependent cytotoxicity of 8-hydroxyquinoline derivatives correlates with their hydrophobicity and does not require caspase activation.

scientific article published on 3 December 2012

Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells

scientific article published on 12 July 2019

Expanding targets for a metabolic therapy of cancer: L-asparaginase.

scientific article published on January 2012

Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification

scientific article published on 19 June 2014

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts

scientific article

Glutamine stimulates mTORC1 independent of the cell content of essential amino acids.

scientific article

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

scientific article

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

scientific article published on 22 October 2012

Improving the metabolic fidelity of cancer models with a physiological cell culture medium

article

L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells.

scientific article

Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication

scientific article published on 11 March 2020

Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells.

scientific article published on 30 May 2006

Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth

scientific article

Platelet gel in the treatment of cutaneous ulcers: the experience of the Immunohaematology and Transfusion Centre of Parma ⬇️

scientific article published on October 1, 2010

Polyphenon E(R), a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis.

scientific article published on 16 December 2013

Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

scientific article published in 2021

Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes

scientific article published in August 2005

Synthesis, structural characterisation and solution chemistry of ruthenium(III) triazole-thiadiazine complexes

scientific article

TOE1 interacts with p53 to modulate its transactivation potential

scientific article

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

scientific article published on 18 September 2017

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

scientific article published on 07 January 2021

The inhibition of glutamine synthetase sensitizes human sarcoma cells to L-asparaginase

scientific article published on 26 January 2007

The non-proteinogenic amino acids L-methionine sulfoximine and DL-phosphinothricin activate mTOR.

scientific article

The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells

scientific article

Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells.

scientific article published on 21 March 2007

List of works by Saverio Tardito

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

Cancer metabolism at a glance

Cell Culture Medium Formulation and Its Implications in Cancer Metabolism

Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells.

Copper compounds in anticancer strategies

Copper-dependent cytotoxicity of 8-hydroxyquinoline derivatives correlates with their hydrophobicity and does not require caspase activation.

Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells

Expanding targets for a metabolic therapy of cancer: L-asparaginase.

Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts

Glutamine stimulates mTORC1 independent of the cell content of essential amino acids.

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

Improving the metabolic fidelity of cancer models with a physiological cell culture medium

L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells.

Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication

Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells.

Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth

Platelet gel in the treatment of cutaneous ulcers: the experience of the Immunohaematology and Transfusion Centre of Parma ⬇️

Polyphenon E(R), a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis.

Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes

Synthesis, structural characterisation and solution chemistry of ruthenium(III) triazole-thiadiazine complexes

TOE1 interacts with p53 to modulate its transactivation potential

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

The inhibition of glutamine synthetase sensitizes human sarcoma cells to L-asparaginase

The non-proteinogenic amino acids L-methionine sulfoximine and DL-phosphinothricin activate mTOR.

The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells

Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells.