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List of works by Clemens Decristoforo

(68)Ga-PSMA PET/CT for restaging recurrent prostate cancer: which factors are associated with PET/CT detection rate?

scientific article published on 15 May 2015

(68)Ga-PSMA PET/CT imaging of metastatic clear cell renal cell carcinoma.

scientific article published on 23 April 2014

(68)Ga-PSMA ligand PET versus (18)F-NaF PET: evaluation of response to (223)Ra therapy in a prostate cancer patient.

scientific article

68Ga- and 111In-labelled DOTA-RGD peptides for imaging of alphavbeta3 integrin expression

scientific article published on 28 March 2008

68Ga-DOTA-TOC uptake in neuroendocrine tumour and healthy tissue: differentiation of physiological uptake and pathological processes in PET/CT.

scientific article published on 5 January 2013

68Ga-DOTA-Tyr3-Octreotide PET in Neuroendocrine Tumors: Comparison with Somatostatin Receptor Scintigraphy and CT

scientific article published on 01 April 2007

68Ga-DOTA-Tyr3-octreotide PET for assessing response to somatostatin-receptor-mediated radionuclide therapy

scientific article published on 18 August 2009

68Ga-PSMA-11 PET/CT in primary staging of prostate cancer: PSA and Gleason score predict the intensity of tracer accumulation in the primary tumour

scientific article

99m-Technetium-labelled peptide-HYNIC conjugates: effects of lipophilicity and stability on biodistribution

scientific article published on 01 May 1999

99mTc-EDDA/HYNIC-TOC and (18)F-FDG in thyroid cancer patients with negative (131)I whole-body scans.

scientific article published on 19 November 2003

99mTc-EDDA/HYNIC-TOC scintigraphy in oncological diagnostics: methodological considerations

scientific article

99mTc-EDDA/HYNIC-TOC: a new 99mTc-labelled radiopharmaceutical for imaging somatostatin receptor-positive tumours: first clinical results and intra-patient comparison with 111In-labelled octreotide derivatives

scientific article published on 01 September 2000

99mTc-EDDA/HYNIC-Tyr(3)-octreotide for staging and follow-up of patients with neuroendocrine gastro-entero-pancreatic tumors.

scientific article published in September 2005

99mTc-HYNIC-[Tyr3]-octreotide for imaging somatostatin-receptor-positive tumors: preclinical evaluation and comparison with 111In-octreotide

scientific article published on 01 June 2000

99mTc-N4-[Tyr3]Octreotate Versus 99mTc-EDDA/HYNIC-[Tyr3]Octreotide: an intrapatient comparison of two novel Technetium-99m labeled tracers for somatostatin receptor scintigraphy.

scientific article

99mTc-labeling and in vitro and in vivo evaluation of HYNIC- and (Nalpha-His)acetic acid-modified [D-Glu1]-minigastrin.

scientific article published on July 2004

99mTc-labelled HYNIC-minigastrin with reduced kidney uptake for targeting of CCK-2 receptor-positive tumours

scientific article published on 17 February 2007

A fully automated synthesis for the preparation of 68Ga-labelled peptides.

scientific article published in November 2007

A novel CCK2/gastrin receptor-localizing radiolabeled peptide probe for personalized diagnosis and therapy of patients with progressive or metastatic medullary thyroid carcinoma: a multicenter phase I GRAN-T-MTC study

scientific article published on 05 December 2018

A retrospective comparison between 68Ga-DOTA-TOC PET/CT and 18F-DOPA PET/CT in patients with extra-adrenal paraganglioma.

scientific article

A simple two-strip method to determine the radiochemical purity of technetium-99m mercaptoacetyltriglycine

scientific article published on 01 April 1993

An intrapatient comparison of 99mTc-EDDA/HYNIC-TOC with 111In-DTPA-octreotide for diagnosis of somatostatin receptor-expressing tumors

scientific article published in May 2003

An iron-mimicking, Trojan horse-entering fungi--has the time come for molecular imaging of fungal infections?

scientific article published on 29 January 2015

Analysis of accumulation of 99mTc-octreotide and 99mTc-EDDA/HYNIC-Tyr3-octreotide in the rat kidneys.

scientific article published in February 2004

Are we "preparing" radiopharmaceuticals?

scientific article published on 22 July 2016

Bone metastases in patients with neuroendocrine tumor: 68Ga-DOTA-Tyr3-octreotide PET in comparison to CT and bone scintigraphy.

scientific article published on 17 July 2009

Brain perfusion scintigraphy with 99mTc-HMPAO or 99mTc-ECD and 123I-beta-CIT single-photon emission tomography in dementia of the Alzheimer-type and diffuse Lewy body disease

scientific article

Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m

article

Clinical translation of theranostic radiopharmaceuticals: Current regulatory status and recent examples

scientific article published on 21 March 2019

Comparison of 68Ga-DOTATATE and 68Ga-DOTANOC PET/CT imaging in the same patient group with neuroendocrine tumours

scientific article published on 20 April 2012

Comparison of 68Ga-labeled RGD mono- and multimers based on a clickable siderophore-based scaffold

scientific article published on 25 October 2019

Comparison of Ga-68-Labeled Fusarinine C-Based Multivalent RGD Conjugates and [(68)Ga]NODAGA-RGD-In Vivo Imaging Studies in Human Xenograft Tumors

scientific article published on 23 February 2016

Comparison of PEGylated and non-PEGylated proticles: An in vitro and in vivo study

scientific article published on 02 September 2019

Comparison of [68Ga]Ga-PSMA-11 PET/CT with [18F]NaF PET/CT in the evaluation of bone metastases in metastatic prostate cancer patients prior to radionuclide therapy

scientific article published on 16 May 2018

Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607.

scientific article

Comparison of different methods for radiochemical purity testing of [99mTc-EDDA-HYNIC-D-Phe1,Tyr3]-octreotide.

scientific article

Comparison of in vitro and in vivo properties of [99mTc]cRGD peptides labeled using different novel Tc-cores.

scientific article

Correction: Klingler, M., et al. Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m. Pharmaceuticals 2019, 12, 13

scientific article published on 13 June 2019

Current status of theranostics in prostate cancer.

scientific article published on 28 December 2017

Cyclic minigastrin analogues for gastrin receptor scintigraphy with technetium-99m: preclinical evaluation.

scientific article published in August 2009

Cyclic versus Noncyclic Chelating Scaffold for 89Zr-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression

scientific article published on 21 November 2017

DOTA-MGS5, a New Cholecystokinin-2 Receptor-Targeting Peptide Analog with an Optimized Targeting Profile for Theranostic Use

scientific article published on 07 December 2018

Design and evaluation of novel radiolabelled VIP derivatives for tumour targeting

scientific article published in April 2013

Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging?

scholarly article by Alicia Vall-Sagarra et al published 4 July 2018 in Pharmaceuticals

Detection of somatostatin receptor-positive tumours using the new 99mTc-tricine-HYNIC-d-Phel-Tyr3-octreotide: first results in patients and comparison with 111In-DTPA-D-Phe1-octreotide

scientific article published on 01 October 2000

Determination of Sn(II) in technetium cold kits by voltammetry at the hanging mercury drop electrode (HMDE) and relevant radiopharmaceutical applications

scientific article published on 01 October 1998

Developing Targeted Hybrid Imaging Probes by Chelator Scaffolding

scientific article

EANM guideline for the preparation of an Investigational Medicinal Product Dossier (IMPD)

scientific article published on 01 November 2014

EANM guideline on the validation of analytical methods for radiopharmaceuticals

scientific article published on 12 February 2020

Early PET imaging with [68]Ga-PSMA-11 increases the detection rate of local recurrence in prostate cancer patients with biochemical recurrence.

scientific article published on 6 June 2017

Early dynamic imaging in 68Ga- PSMA-11 PET/CT allows discrimination of urinary bladder activity and prostate cancer lesions

scientific article

Erratum to: Guideline for PET/CT imaging of neuroendocrine neoplasms with (68)Ga-DOTA-conjugated somatostatin receptor targeting peptides and (18)F-DOPA.

scientific article

Erratum: Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting: Erratum

scientific article published on 19 June 2019

Erythroid 5-aminolevulinate synthase, ferrochelatase and DMT1 expression in erythroid progenitors: differential pathways for erythropoietin and iron-dependent regulation

scientific article (publication date: August 2002)

European regulations for the introduction of novel radiopharmaceuticals in the clinical setting.

scientific article

Evaluation of [123I]IBZM pinhole SPECT for the detection of striatal dopamine D2 receptor availability in rats.

scientific article published on 24 November 2004

Evaluation of striatal dopamine transporter function in rats by in vivo beta-[123I]CIT pinhole SPECT.

scientific article published in September 2002

Evidence for Somatostatin receptor 2 in thyroid tissue.

scientific article

Exploiting the Concept of Multivalency with 68Ga- and 89Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression.

scientific article published on 10 April 2018

Expression of somatostatin receptor subtype 2 and subtype 5 in thyroid malignancies

scientific article published on 26 June 2014

Failure of labelling of anti-granulocyte antibody

scientific article published on 01 June 1993

Feasibility and availability of ⁶⁸Ga-labelled peptides.

scientific article published on February 2012

From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial

scientific article published on 27 January 2016

Full automation of (68)Ga labelling of DOTA-peptides including cation exchange prepurification.

scientific article published on 24 October 2009

Functional imaging in phaeochromocytoma and neuroblastoma with 68Ga-DOTA-Tyr 3-octreotide positron emission tomography and 123I-metaiodobenzylguanidine

scientific article published on 29 January 2011

Functional imaging in phaeochromocytoma and neuroblastoma with 68Ga-DOTA-Tyr3-octreotide positron emission tomography and 123I-metaiodobenzylguanidine: a clarification.

scientific article published in March 2012

Fusarinine C, a novel siderophore-based bifunctional chelator for radiolabeling with Gallium-68.

scientific article published on 15 April 2015

Gallium-68 -- a new opportunity for PET available from a long shelf-life generator - automation and applications

scientific article published on 01 July 2012

Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals

scientific article

Guidance on current good radiopharmacy practice for the small-scale preparation of radiopharmaceuticals using automated modules: a European perspective

scientific article published on 01 August 2014

Guideline for PET/CT imaging of neuroendocrine neoplasms with 68Ga-DOTA-conjugated somatostatin receptor targeting peptides and 18F-DOPA.

scientific article published on 25 May 2017

Harmonization of United States, European Union and Canadian First-in-Human Regulatory Requirements for Radiopharmaceuticals-Is This Possible?

scientific article published on 27 September 2018

Highlights lecture EANM 2015: the search for nuclear medicine's superheroes

scientific article

Highlights of the 30th Annual Congress of the EANM, Vienna 2017: "Yes we can - make nuclear medicine great again"

article

Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C-Proof of Concept

scientific article published on 01 May 2020

Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores

scientific article published on 22 January 2020

Image fusion analysis of (99m)Tc-HYNIC-Tyr(3)-octreotide SPECT and diagnostic CT using an immobilisation device with external markers in patients with endocrine tumours.

scientific article published on 26 August 2005

Image fusion analysis of 99m Tc-HYNIC-octreotide scintigraphy and CT/MRI in patients with thyroid-associated orbitopathy: the importance of the lacrimal gland.

scientific article published on 13 June 2003

Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography

scientific article published in Scientific Reports

Improved quality control of [177Lu]Lu-PSMA I&T

Impurity in (68)Ga-peptide preparation using processed generator eluate.

scientific article published on 11 February 2010

In Vitro and In Vivo Comparison of Selected Ga-68 and Zr-89 Labelled Siderophores.

scientific article published on 30 September 2015

In Vivo Characterization of 4 Ga-Labeled Multimeric RGD Peptides to Image αβ Integrin Expression in 2 Human Tumor Xenograft Mouse Models

In vitro and in vivo evaluation of a novel 99mTc(CO)3-pyrazolyl conjugate of cyclo-(Arg-Gly-Asp-d-Tyr-Lys).

scientific article published on March 2007

In vitro and in vivo evaluation of selected 68Ga-siderophores for infection imaging

scientific article published on 14 December 2011

Influence of PEGylation and RGD loading on the targeting properties of radiolabeled liposomal nanoparticles

scientific article

Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue

scientific article

Influence of biological assay conditions on stability assessment of radiometal-labelled peptides exemplified using a 177Lu-DOTA-minigastrin derivative.

scientific article

Methodological considerations influence the clinical value of parathyroid localisation diagnostics

scientific article published on 01 July 2001

Microbial challenge tests on nonradioactive TiO2-based 68Ge/68Ga generator columns

scientific article published in August 2012

Modifying the Siderophore Triacetylfusarinine C for Molecular Imaging of Fungal Infection

scientific article published on 01 December 2019

Molecular Design of <sup>68</sup>Ga- and <sup>89</sup>Zr-Labeled Anticalin Radioligands for PET-Imaging of PSMA-Positive Tumors

Molecular Imaging: In Vivo Agents for the Diagnosis and Treatment of Cancer

scientific article published on 22 October 2018

Multimerization results in formation of re-bindable metabolites: A proof of concept study with FSC-based minigastrin imaging probes targeting CCK2R expression

scientific article published in PLoS ONE

Myocardial fatty acid metabolism during acute cardiac allograft rejection

scientific article published on 01 January 1998

Novel 99mTc '4 + 1' peptide conjugates: tuning the biodistribution by variation of coligands.

scientific article published on 12 May 2010

Novel Bifunctional Cyclic Chelator for (89)Zr Labeling-Radiolabeling and Targeting Properties of RGD Conjugates

scientific article published on 19 May 2015

On-cartridge preparation and evaluation of 68Ga-, 89Zr- and 64Cu-precursors for cell radiolabelling

scientific article published on 15 April 2019

Peptide targeted imaging of cancer.

scientific article published on October 2003

Position paper on requirements for toxicological studies in the specific case of radiopharmaceuticals

article

Preclinical evaluation of radiolabeled DOTA-derivatized cyclic minigastrin analogs for targeting cholecystokinin receptor expressing malignancies.

scientific article published on June 2012

Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging.

scientific article

Preclinical pharmacokinetics, biodistribution, radiation dosimetry and toxicity studies required for regulatory approval of a phase I clinical trial with (111)In-CP04 in medullary thyroid carcinoma patients

scientific article published on 13 May 2016

Preparation, 99mTc-labeling, and in vitro characterization of HYNIC and N3S modified RC-160 and [Tyr3]octreotide

scientific article published on May 1999

Preparation,99mTc-Labeling, and in Vitro Characterization of Hynic and N3S Modified RC-160 and [TYR3]octreotide

scientific article published on 01 July 1999

Pretargeted Imaging with Gallium-68-Improving the Binding Capability by Increasing the Number of Tetrazine Motifs

article

Problems with fractionated cold kits

scientific article published on 01 November 1996

Radiochemical purity of routinely prepared 99Tcm radiopharmaceuticals: A retrospective study

scientific article published on 01 April 2000

Radiolabeling of lipid-based nanoparticles for diagnostics and therapeutic applications: a comparison using different radiometals

scientific article published in September 2010

Radiolabelling of peptides for PET, SPECT and therapeutic applications using a fully automated disposable cassette system

scientific article published in October 2011

Radionuclides: medicinal products or rather starting materials?

scientific article published on 20 August 2019

Radiopharmaceutical development of a freeze-dried kit formulation for the preparation of [99mTc-EDDA-HYNIC-D-Phe1, Tyr3]-octreotide, a somatostatin analog for tumor diagnosis

scientific article published on October 2004

Radiopharmaceuticals are special, but is this recognized? The possible impact of the new Clinical Trials Regulation on the preparation of radiopharmaceuticals

scientific article published in November 2014

Radiopharmacy: regulations and legislations in relation to human applications

scientific article

Rational Design, Synthesis and Preliminary Evaluation of Novel Fusarinine C-Based Chelators for Radiolabeling with Zirconium-89

article

Role of radiopharmaceuticals in the diagnosis and treatment of neuroendocrine tumours

scientific article

Selected ⁶⁸Ga-siderophores versus ⁶⁸Ga-colloid and ⁶⁸Ga-citrate: biodistribution and small animal imaging in mice

scientific article published on 29 October 2014

Selection of the First <sup>99m</sup>Tc-Labelled Somatostatin Receptor Subtype 2 Antagonist for Clinical Translation-Preclinical Assessment of Two Optimized Candidates

scientific article published on 28 December 2020

Siderophore Scaffold as Carrier for Antifungal Peptides in Therapy of <i>Aspergillus fumigatus</i> Infections

scientific article published on 15 December 2020

Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections-Current Status and Future Perspectives

scientific article published on 29 May 2020

Siderophores for molecular imaging applications.

scientific article published on 11 October 2016

Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting.

scientific article published on 16 April 2018

Small animal imaging using a conventional gamma camera exemplified in studies on the striatal dopaminergic system.

scientific article published in January 2006

Somatostatin receptor PET in neuroendocrine tumours: 68Ga-DOTA0,Tyr3-octreotide versus 68Ga-DOTA0-lanreotide ⬇️

scientific article published on November 14, 2012

Somatostatin receptor scintigraphy using (99m)Tc-EDDA/HYNIC-TOC in graves' disease

scientific article published in September 2002

Surfactant protein B labelled with [99mTc(CO)3(H2O)3]+ retains biological activity in vitro

scientific article published on 01 April 2001

Synthesis, in vitro and in vivo evaluation of 18F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors

scientific article published on 17 November 2017

Targeting Gastrointestinal Stromal Tumor with 68Ga-Labeled Peptides: An In Vitro Study on Gastrointestinal Stromal Tumor-Cell Lines.

scientific article published on October 2016

Targeting properties of peptide-modified radiolabeled liposomal nanoparticles

scientific article published on 20 May 2011

Technetium-99m human immunoglobulin scintigraphy in psoriatic arthropathy: first results

scientific article published on 01 April 1994

Technetium-99m somatostatin analogues: effect of labelling methods and peptide sequence

scientific article published on 01 August 1999

The 68Ga/177Lu theragnostic concept in PSMA targeting of castration-resistant prostate cancer: correlation of SUVmax values and absorbed dose estimates.

scientific article published on 12 January 2017

The Siderophore Transporter Sit1 Determines Susceptibility to the Antifungal VL-2397

scientific article published on 23 September 2019

The influence of chelator on the pharmacokinetics of 99mTc-labelled peptides.

scientific article

The new Regulation on clinical trials in relation to radiopharmaceuticals: when and how will it be implemented?

scientific article published on 11 January 2019

The specific case of radiopharmaceuticals and GMP—activities of the Radiopharmacy Committee

scientific article published on 15 May 2008

The use of electronic autoradiography in radiopharmacy

scientific article published on 01 May 1997

Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles

scientific article published on 05 December 2013

US and EU radiopharmaceutical diagnostic and therapeutic nonclinical study requirements for clinical trials authorizations and marketing authorizations

scientific article published on 22 May 2019

Ultra-low activities of a common radioisotope for permission-free tracking of a drosophilid fly in its natural habitat

scientific article

Untangling the web of European regulations for the preparation of unlicensed radiopharmaceuticals: a concise overview and practical guidance for a risk-based approach.

scientific article

[(68)Ga]FSC-(RGD)3 a trimeric RGD peptide for imaging αvβ3 integrin expression based on a novel siderophore derived chelating scaffold-synthesis and evaluation

scientific article

[(68)Ga]NODAGA-RGD - Metabolic stability, biodistribution, and dosimetry data from patients with hepatocellular carcinoma and liver cirrhosis

scientific article

[68Ga]NODAGA-RGD for imaging αvβ3 integrin expression.

scientific article published on 13 April 2011

[99mTc]HYNIC-RGD for imaging integrin alphavbeta3 expression

scientific article published on November 2006

[99mTc]demotensin VI: biodistribution and initial clinical results in tumor patients of a pilot/phase I study

scientific article published in September 2011

[Quality control of radiopharmaceuticals from the clinical aspect--a necessity?]

scientific article published on 01 June 1993

[⁶⁸Ga]NS₃-RGD and [⁶⁸Ga] Oxo-DO3A-RGD for imaging α(v)β₃ integrin expression: synthesis, evaluation, and comparison.

scientific article

⁶⁸Ga-DOTA⁰-Tyr³-octreotide positron emission tomography in head and neck squamous cell carcinoma.

scientific article published on 18 May 2013

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