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List of works by Peter Broderick

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

article

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

article

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

scientific journal article

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

scientific journal article

A genome-wide association study of tag SNPs identify five novel colorectal cancer susceptibility loci

article

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

article

A genome-wide scan of 10 000 gene-centric variants and colorectal cancer risk

scientific article

A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants

scientific article

A retrospective observational study of the relationship between single nucleotide polymorphisms associated with the risk of developing colorectal cancer and survival ⬇️

scientific article

Abstract 942: Imputation from The 1000 Genomes Project identifies rare large effect variants of BRCA2-K3326X and CHEK2-I157T as risk factors for lung cancer; a study from the TRICL consortium

article published in 2014

Abstract P3-08-04: Impact of CYP3A variation on estrone levels and breast cancer risk

Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

scientific article

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

scientific article published on 14 May 2019

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

scientific article published in Nature Communications

Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

scientific article published in Nature Communications

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

scientific article published in Nature Communications

CASP8 variants D302H and -652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population

scientific article published on 25 March 2008

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.

scientific article

CYP3A variation, premenopausal estrone levels, and breast cancer risk

scientific article published on 3 April 2012

CanVar: A resource for sharing germline variation in cancer patients

scientific article

Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk

scientific article (publication date: 29 April 2011)

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

scientific article

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

scientific article published on 16 December 2007

Common genetic variation at 15q25.2 impacts on chronic lymphocytic leukaemia risk

scientific article published on 9 May 2011

Common genetic variation contributes significantly to the risk of developing chronic lymphocytic leukemia

scientific article published on 16 August 2012

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

scientific article published on 10 January 2010

Common variation at 10p12.31 near MLLT10 influences meningioma risk

scientific article

Common variation at 1q24.1 (ALDH9A1) is a potential risk factor for renal cancer

scientific article

Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer

scientific journal article

Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

scientific journal article

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

scientific journal article

Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia

scientific article

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

scientific article

Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk

scientific article published on 02 December 2008

Comprehensive evaluation of the impact of 14 genetic variants on colorectal cancer phenotype and risk

scientific article published on 07 December 2011

Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals

scientific article published on 05 April 2012

Cytochrome P450 Allele CYP3A7*1C Associates with Adverse Outcomes in Chronic Lymphocytic Leukemia, Breast, and Lung Cancer

scientific article published on 10 March 2016

DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors

scientific article

Deciphering the 8q24.21 association for glioma

scientific article published on 11 February 2013

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer

scientific article published on 30 July 2013

Deciphering the genetics of hereditary non-syndromic colorectal cancer

scientific article published on 16 July 2008

Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study

scientific article

Erratum: COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer

article

Erratum: Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

scholarly article published in Nature Genetics

Erratum: Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

scientific article published in June 2013

Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition

scientific article

Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma

scientific article published on 11 May 2011

FGFR2 genotype and risk of radiation-associated breast cancer in Hodgkin lymphoma

article published in 2011

Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes

scientific article

Fine-scale mapping of the 6p25.3 chronic lymphocytic leukaemia susceptibility locus.

scientific article published in February 2010

Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology ⬇️

scholarly article by Molly Went et al published 21 December 2018 in Blood Cancer Journal

Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.

scientific article

Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men

scientific article

Genome-wide association analysis identifies a meningioma risk locus at 11p15.5

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

scientific article published on 30 March 2008

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

scientific journal article

Genome-wide association study identifies multiple susceptibility loci for glioma ⬇️

scientific article

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma ⬇️

scientific article

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia ⬇️

scientific article published on 9 April 2018

Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma

scientific article published on 07 September 2018

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

scientific article published in December 2017

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

scientific article published on 27 March 2017

Genome-wide association study on differentiated thyroid cancer

scientific journal article

Genomic landscape of platinum resistant and sensitive testicular cancers

scientific article published on 04 May 2020

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas ⬇️

scientific article

Germline mutations in shelterin complex genes are associated with familial chronic lymphocytic leukemia

scientific article

IRF4 polymorphism rs872071 and risk of Hodgkin lymphoma

scientific article published on 5 October 2009

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ⬇️

scientific article published on 12 June 2017

Identification of four new susceptibility loci for testicular germ cell tumour ⬇️

scientific article published on 27 October 2015

Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk

scientific article published on 25 November 2019

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

scientific article

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

scientific article published in Nature Communications

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

scientific article

Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma ⬇️

scientific article published on 24 July 2015

Inherited genetic susceptibility to monoclonal gammopathy of unknown significance

scientific article published on 21 January 2014

Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma

scientific article

Lack of a relationship between the common 18q24 variant rs12953717 and risk of chronic lymphocytic leukemia

Lack of a relationship between the common 8q24 variant rs6983267 and risk of chronic lymphocytic leukemia

Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene

scientific article published on 9 February 2018

Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222.

scientific article published on 9 April 2013

MLH1-93G > A is a risk factor for MSI colorectal cancer

scientific article published on 11 May 2011

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

scientific article

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

scientific article

MiMiR: a comprehensive solution for storage, annotation and exchange of microarray data

scientific article

Multiple Hodgkin lymphoma-associated loci within the HLA region at chromosome 6p21.3

scientific article published on 19 May 2011

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer

scientific article

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

scientific article

National study of colorectal cancer genetics

scientific article published on 25 September 2007

Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study

scientific article published on 24 January 2011

Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer

scientific article published in October 2018

Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. ⬇️

scientific article

Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility ⬇️

scientific article published on 20 December 2016

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

scientific journal article

Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer ⬇️

scientific article

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer

article

Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients

scientific article published on 31 October 2011

Risk of developing chronic lymphocytic leukemia is influenced by HLA-A class I variation

scientific article published on 02 July 2012

Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers

scientific article

Search for inherited susceptibility to radiation-associated meningioma by genomewide SNP linkage disequilibrium mapping

scientific article published on March 2011

The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4

scientific article published on 12 December 2011

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

scientific article

The CDH1-160C>A polymorphism is a risk factor for colorectal cancer.

scientific article published in October 2009

The TERT variant rs2736100 is associated with colorectal cancer risk

scientific article

The association of rs1051730 genotype on adherence to and consumption of prescribed nicotine replacement therapy dose during a smoking cessation attempt

scientific article published on 10 April 2015

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression

scientific article

Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes

scientific article published on 29 June 2016

Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review

scientific article

Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer

scientific article published on 7 December 2017

Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia.

scientific article published on 21 January 2010

Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma

scientific journal article

Variation in TP63 is associated with lung adenocarcinoma in the UK population

scientific article published on 24 May 2011

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

scientific article

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