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List of works by Rainer Lehtonen

A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients

scientific article published on 01 June 2018

A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis.

scientific article published in October 2005

Alternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma.

scientific article published on 25 August 2017

Anagrelide for Gastrointestinal Stromal Tumor

scientific article published on 07 December 2018

Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma

scientific article published on 22 April 2011

Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer

article

Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients

scientific article published in July 2006

BMPR2mutation in a patient with pulmonary arterial hypertension and suspected hereditary hemorrhagic telangiectasia

scientific article published on 01 October 2008

Background Mutation Frequency in Microsatellite-Unstable Colorectal Cancer

scientific article published on 01 June 2007

Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance

scientific article published on 23 June 2021

Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

scientific article published on 09 September 2016

Computational identification of cancer susceptibility loci.

scientific article published on January 2010

Computational identification of candidate loci for recessively inherited mutation using high-throughput SNP arrays

scientific article published on 17 May 2007

Cytochrome P450 gene CYP337 and heritability of fitness traits in the Glanville fritillary butterfly

scientific article published on 5 April 2014

Data integration to prioritize drugs using genomics and curated data.

scientific article

Definition of a minimal region of deletion of chromosome 7 in uterine leiomyomas by tiling-path microarray CGH and mutation analysis of known genes in this region

article

Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma

scientific article published on 9 February 2017

Distinct subtypes of diffuse large B-cell lymphoma defined by hypermutated genes

scientific article published on 11 June 2019

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

scientific article published in June 2006

Effects of ambient and preceding temperatures and metabolic genes on flight metabolism in the Glanville fritillary butterfly

scientific article published on December 2015

Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma

scientific article published on 11 May 2011

Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.

scientific article

Fine mapping of 11q13.5 identifies regions associated with prostate cancer and prostate cancer death

scientific article published on 02 July 2013

Flight-induced changes in gene expression in the Glanville fritillary butterfly.

scientific article published on 31 August 2015

Genetic effects on life-history traits in the Glanville fritillary butterfly

scientific article

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

article

Genomic profile of pseudomyxoma peritonei analyzed using next-generation sequencing and immunohistochemistry

Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma

scientific article

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

scientific article

High genetic load in an old isolated butterfly population.

scientific article

Identification of Prognostic Groups in High-Grade Serous Ovarian Cancer Treated with Platinum-Taxane Chemotherapy.

scientific article

Identification of sample-specific regulations using integrative network level analysis

scientific article published on 28 April 2015

Identifying differentially methylated sites in samples with varying tumor purity

scientific article published on 01 September 2018

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

scientific article published on 19 March 2019

Lep-MAP: fast and accurate linkage map construction for large SNP datasets

scientific article

Little evidence for involvement of MLH3 in colorectal cancer predisposition

scientific article

Mathematical Modeling Predicts Response to Chemotherapy and Drug Combinations in Ovarian Cancer

scientific article published on 16 May 2018

MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma.

scientific article

Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

scientific article

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome

scientific article

Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer

article

Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers

scientific article published on June 2005

Nationwide registry-based analysis of cancer clustering detects strong familial occurrence of Kaposi sarcoma

scientific article

No evidence for a genetic modifier for renal cell cancer risk in HLRCC syndrome.

scientific article published in June 2010

No germline FH mutations in familial breast cancer patients

PerPAS: Topology-Based Single Sample Pathway Analysis Method.

scientific article

Phenotypic plasticity in thermal tolerance in the Glanville fritillary butterfly.

scientific article

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

scientific article published in May 2006

Plastic larval development in a butterfly has complex environmental and genetic causes and consequences for population dynamics

scientific article

Predictable allele frequency changes due to habitat fragmentation in the Glanville fritillary butterfly.

scientific article

Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps

scientific article published on 08 February 2013

Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer

scientific article published on 03 May 2019

Recessively inherited right atrial isomerism caused by mutations in growth/differentiation factor 1 (GDF1)

article published in 2010

Rule-based induction method for haplotype comparison and identification of candidate disease loci

scientific article published on 19 March 2012

SNP design from 454 sequencing of Podosphaera plantaginis transcriptome reveals a genetically diverse pathogen metapopulation with high levels of mixed-genotype infection

scientific article

SePIA: RNA and small RNA sequence processing, integration, and analysis.

scientific article

Temperature- and sex-related effects of serine protease alleles on larval development in the Glanville fritillary butterfly

scientific article published on 4 September 2015

The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera

scientific article

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.

scientific article published on 28 June 2009

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