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List of works by Jan Terje Andersen

A human endothelial cell-based recycling assay for screening of FcRn targeted molecules

scientific article published on 12 February 2018

A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes

scientific article published on 02 December 2019

A receptor-mediated mechanism to support clinical observation of altered albumin variants

scientific article published on 01 December 2007

A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance

scientific article published on 21 November 2012

A strategy for bacterial production of a soluble functional human neonatal Fc receptor

scientific article published on 10 December 2007

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

scientific article published on 01 October 2020

An intact C-terminal end of albumin is required for its long half-life in humans

scientific article published on 20 April 2020

Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life

scientific article

Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

scientific article published on 29 August 2019

Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

scientific article published on 10 January 2022

Antibody-antigen kinetics constrain intracellular humoral immunity

scientific article

Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

scientific article published on 14 January 2019

Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses

scientific article published on 18 December 2019

Characterization of an FcgammaRI-binding peptide selected by phage display

scientific article published on 19 January 2006

Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation

scientific article published on 23 September 2013

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

scientific article

Complement C4 Prevents Viral Infection through Capsid Inactivation

scientific article published on 26 March 2019

Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity

scientific article

Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

scientific article published on 14 December 2009

Dependence of antibody-mediated presentation of antigen on FcRn

scholarly article

Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications

scientific article

Dissecting the interaction between transglutaminase 2 and fibronectin

scientific article

Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies

scientific article published on 24 April 2014

Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn

scientific article published on 13 November 2014

Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity

scientific article

Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin

scientific article published on 06 August 2020

Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization

scientific article published on 21 December 2015

Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain

scientific article

Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding

scientific article

Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions

scientific article published on 22 April 2015

FcRn binding properties of an abnormal truncated analbuminemic albumin variant

scientific article

FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity

scientific article published on 01 October 2020

Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury

scientific article

Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport

scientific article published on 20 January 2018

Human and mouse albumin bind their respective neonatal Fc receptors differently

scientific article published in Scientific Reports

Identification of a high affinity FcgammaRIIA-binding peptide that distinguishes FcgammaRIIA from FcgammaRIIB and exploits FcgammaRIIA-mediated phagocytosis and degradation

scientific article

Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn).

scientific article published on 24 October 2014

Intracellular neutralisation of rotavirus by VP6-specific IgG

scientific article published on 04 August 2020

Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues

scientific article

Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions.

scientific article published on 10 July 2013

NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies

scientific article published on 01 January 2020

On the perplexingly low rate of transport of IgG2 across the human placenta

scientific article

Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties.

scientific article

Polymeric human Fc-fusion proteins with modified effector functions

scientific article published on 19 October 2011

Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells

scientific article published on 01 March 2005

Publisher Correction: Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

scientific article published on 01 April 2019

Selection of nanobodies that target human neonatal Fc receptor.

scientific article

Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics

scientific article published on July 2013

Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease

scientific article

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

scientific article

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

scientific article published on 17 September 2020

TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity

scientific article published on 09 March 2016

TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination

article published in the Proceedings of the National Academy of Sciences of the United States of America

TRIM21-From Intracellular Immunity to Therapy

scientific article published on 28 August 2019

TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity

scientific article

Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate 177Lu-NNV003

scientific article published on 15 July 2019

The Neonatal Fc Receptor (FcRn): A Misnomer?

scientific article published on 10 July 2019

The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure

scientific article published on 25 March 2014

The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin

scientific article

The neonatal Fc receptor in mucosal immune regulation

scientific article published on 22 December 2020

The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery

scientific article (publication date: August 2015)

The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics.

scientific article published on January 2009

Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies

scientific article published on 13 April 2015

Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics

scientific article

Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

scientific article published on 01 December 2020

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