List of works - Sara N. Richter

A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids

scientific article published on 29 October 2018

A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety

article

A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication

scientific article (publication date: 24 May 2017)

A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription

scientific article published on 01 December 2019

A photoreactive G-quadruplex ligand triggered by green light.

scientific article published on 15 December 2014

A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging.

scientific article published on 2 February 2017

Anti-HIV-1 activity of the G-quadruplex ligand BRACO-19.

scientific article published on 6 August 2014

Antimicrobial treatment and containment measures for an extremely drug-resistant Klebsiella pneumoniae ST101 isolate carrying pKPN101-IT, a novel fully sequenced bla(KPC-2) plasmid

scientific article published on 12 September 2012

Antiviral 6-amino-quinolones: molecular basis for potency and selectivity

scientific article published in October 2005

Antiviral properties of quinolone-based drugs.

scientific article published on June 2004

Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells

scientific article

BINOL-amino acid conjugates as triggerable carriers of DNA-targeted potent photocytotoxic agents

scientific article

Bipyridyl ligands as photoactivatable mono- and bis-alkylating agents capable of DNA cross-linking

scientific article published on 16 November 2006

Characterisation of qnr plasmid-mediated quinolone resistance in Enterobacteriaceae from Italy: association of the qnrB19 allele with the integron element ISCR1 in Escherichia coli

scientific article

Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action.

scientific article

Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage

scientific article published on 13 April 2006

Comparison of phenotypic methods for the detection of carbapenem non-susceptible Enterobacteriaceae

scientific article

Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA.

scientific article published on 19 October 2004

Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops

scientific article

Conserved G-Quadruplexes Regulate the Immediate Early Promoters of Human

scientific article published on 27 June 2019

Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses

scientific article (publication date: 17 May 2017)

Differential targeting of unpaired bases within duplex DNA by the natural compound clerocidin: a valuable tool to dissect DNA secondary structure

scientific article

Dissecting reactivity of clerocidin toward common buffer systems by means of selected drug analogues

scientific article published in January 2005

Down-Regulation of the Androgen Receptor by G-Quadruplex Ligands Sensitizes Castration-Resistant Prostate Cancer Cells to Enzalutamide

scientific article published on 20 September 2018

Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration

scientific article published on 01 August 2019

Effects of common buffer systems on drug activity: the case of clerocidin.

scientific article

Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity

scientific article

Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes

scientific article published on 02 May 2022

G-Quadruplex Visualization in Cells via Antibody and Fluorescence Probe

scientific article published on 01 January 2019

G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide

article published in 2018

G-quadruplex forming sequences in the genome of all known human viruses: a comprehensive guide

scientific article published on 11 June 2018

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

scientific article published on 15 March 2018

HIV-1 Nucleocapsid Protein Unfolds Stable RNA G-Quadruplexes in the Viral Genome and Is Inhibited by G-Quadruplex Ligands

scientific article published on 06 November 2019

Highly Improved Electrospray Ionization-Mass Spectrometry Detection of G-Quadruplex-Folded Oligonucleotides and Their Complexes with Small Molecules

scientific article published on 8 August 2017

Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases

scientific article published on 30 August 2007

Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures.

scientific article

Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization.

scientific article

In vitro basis for schedule-dependent interaction between gemcitabine and topoisomerase-targeted drugs in the treatment of colorectal cancer

scientific article published on May 2006

Inhibition of gene expression in human cells through small molecule-RNA interactions

scientific article

Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative

scientific article published on May 2004

Inhibitors of HIV-1 Tat-mediated transactivation.

scientific article

KPC-mediated resistance in Klebsiella pneumoniae in two hospitals in Padua, Italy, June 2009-December 2011: massive spreading of a KPC-3-encoding plasmid and involvement of non-intensive care units

scientific article

Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop

article

Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions.

scientific article published on 18 July 2017

Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands

scientific article published on 24 January 2019

Naphthalene diimide scaffolds with dual reversible and covalent interaction properties towards G-quadruplex.

scientific article published on 16 June 2011

Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription.

scientific article

Photodynamic Therapy for ras-Driven Cancers: Targeting G-Quadruplex RNA Structures with Bifunctional Alkyl-Modified Porphyrins

scientific article published on 24 January 2020

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

scientific article published on 23 June 2021

Pyrrolo[3',2':6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity

scientific article

Quinone methides tethered to naphthalene diimides as selective G-quadruplex alkylating agents.

scientific article

Rapid detection of blaVIM-1-37 and blaKPC1/2-12 alleles from clinical samples by multiplex PCR-based assays

scientific article published in May 2013

Reactivity of clerocidin towards adenine: implications for base-modulated DNA damage

scientific article published on 23 January 2009

Selective Binding of TAR RNA by a Tat-Derived β-Peptide

scientific article published on 01 October 2003

Serotype epidemiology and multidrug resistance patterns of Salmonella enterica infecting humans in Italy

scientific article published on June 2016

Simocyclinone D8 turns on against Gram-negative bacteria in a clinical setting.

scientific article

Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation

scientific article

Stabilization of Telomere G-Quadruplexes Interferes with Human Herpesvirus 6A Chromosomal Integration.

scientific article

Stable and Conserved G-Quadruplexes in the Long Terminal Repeat Promoter of Retroviruses

scientific article published on 22 May 2019

Strategies for inhibiting function of HIV-1 accessory proteins: a necessary route to AIDS therapy?

scientific article published on January 2009

Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome

scientific article

Surface Plasmon Resonance kinetic analysis of the interaction between G-quadruplex nucleic acids and an anti-G-quadruplex monoclonal antibody.

scientific article published on 7 March 2018

Synthesis and antiproliferative mechanism of action of pyrrolo[3',2':6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers.

scientific article

Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines

scientific article published on 03 November 2018

Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes

scientific article

Targeting loop adenines in G-quadruplex by a selective oxirane.

scientific article published on 04 December 2012

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer.

scientific article published on 16 June 2016

The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell.

scientific article

The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand

scientific article published on 3 April 2015

The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes.

scientific article published on 24 March 2017

The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids

scientific article

The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure

scientific article

Topoisomerase I involvement in schedule-dependent interaction between 5-fluoro-uracil and irinotecan in the treatment of colorectal cancer

scientific article published on 14 March 2009

Topoisomerase I, IIα and IIβ mRNA expression in peripheral blood mononuclear cells of patients with solid tumor: preliminary results

scientific article published on 01 May 2006

Transfer of KPC-2 Carbapenemase from Klebsiella pneumoniae to Escherichia coli in a patient: first case in Europe

scientific article

Ultrarapid detection of blaKPC₁/₂-₁₂ from perirectal and nasal swabs by use of real-time PCR.

scientific article published on 29 February 2012

Water soluble extended naphthalene diimides as pH fluorescent sensors and G-quadruplex ligands.

scientific article

List of works by Sara N. Richter

A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids

A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety

A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication

A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription

A photoreactive G-quadruplex ligand triggered by green light.

A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging.

Anti-HIV-1 activity of the G-quadruplex ligand BRACO-19.

Antimicrobial treatment and containment measures for an extremely drug-resistant Klebsiella pneumoniae ST101 isolate carrying pKPN101-IT, a novel fully sequenced bla(KPC-2) plasmid

Antiviral 6-amino-quinolones: molecular basis for potency and selectivity

Antiviral properties of quinolone-based drugs.

Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells

BINOL-amino acid conjugates as triggerable carriers of DNA-targeted potent photocytotoxic agents

Bipyridyl ligands as photoactivatable mono- and bis-alkylating agents capable of DNA cross-linking

Characterisation of qnr plasmid-mediated quinolone resistance in Enterobacteriaceae from Italy: association of the qnrB19 allele with the integron element ISCR1 in Escherichia coli

Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action.

Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage

Comparison of phenotypic methods for the detection of carbapenem non-susceptible Enterobacteriaceae

Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA.

Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops

Conserved G-Quadruplexes Regulate the Immediate Early Promoters of Human

Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses

Differential targeting of unpaired bases within duplex DNA by the natural compound clerocidin: a valuable tool to dissect DNA secondary structure

Dissecting reactivity of clerocidin toward common buffer systems by means of selected drug analogues

Down-Regulation of the Androgen Receptor by G-Quadruplex Ligands Sensitizes Castration-Resistant Prostate Cancer Cells to Enzalutamide

Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration

Effects of common buffer systems on drug activity: the case of clerocidin.

Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity

Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes

G-Quadruplex Visualization in Cells via Antibody and Fluorescence Probe

G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide

G-quadruplex forming sequences in the genome of all known human viruses: a comprehensive guide

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

HIV-1 Nucleocapsid Protein Unfolds Stable RNA G-Quadruplexes in the Viral Genome and Is Inhibited by G-Quadruplex Ligands

Highly Improved Electrospray Ionization-Mass Spectrometry Detection of G-Quadruplex-Folded Oligonucleotides and Their Complexes with Small Molecules

Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases

Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures.

Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization.

In vitro basis for schedule-dependent interaction between gemcitabine and topoisomerase-targeted drugs in the treatment of colorectal cancer

Inhibition of gene expression in human cells through small molecule-RNA interactions

Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative

Inhibitors of HIV-1 Tat-mediated transactivation.

KPC-mediated resistance in Klebsiella pneumoniae in two hospitals in Padua, Italy, June 2009-December 2011: massive spreading of a KPC-3-encoding plasmid and involvement of non-intensive care units

Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop

Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions.

Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands

Naphthalene diimide scaffolds with dual reversible and covalent interaction properties towards G-quadruplex.

Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription.

Photodynamic Therapy for ras-Driven Cancers: Targeting G-Quadruplex RNA Structures with Bifunctional Alkyl-Modified Porphyrins

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

Pyrrolo[3',2':6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity

Quinone methides tethered to naphthalene diimides as selective G-quadruplex alkylating agents.

Rapid detection of blaVIM-1-37 and blaKPC1/2-12 alleles from clinical samples by multiplex PCR-based assays

Reactivity of clerocidin towards adenine: implications for base-modulated DNA damage

Selective Binding of TAR RNA by a Tat-Derived β-Peptide

Serotype epidemiology and multidrug resistance patterns of Salmonella enterica infecting humans in Italy

Simocyclinone D8 turns on against Gram-negative bacteria in a clinical setting.

Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation

Stabilization of Telomere G-Quadruplexes Interferes with Human Herpesvirus 6A Chromosomal Integration.

Stable and Conserved G-Quadruplexes in the Long Terminal Repeat Promoter of Retroviruses

Strategies for inhibiting function of HIV-1 accessory proteins: a necessary route to AIDS therapy?

Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome

Surface Plasmon Resonance kinetic analysis of the interaction between G-quadruplex nucleic acids and an anti-G-quadruplex monoclonal antibody.

Synthesis and antiproliferative mechanism of action of pyrrolo[3',2':6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers.

Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines

Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes

Targeting loop adenines in G-quadruplex by a selective oxirane.

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer.

The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell.

The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand

The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes.

The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids

The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure

Topoisomerase I involvement in schedule-dependent interaction between 5-fluoro-uracil and irinotecan in the treatment of colorectal cancer

Topoisomerase I, IIα and IIβ mRNA expression in peripheral blood mononuclear cells of patients with solid tumor: preliminary results

Transfer of KPC-2 Carbapenemase from Klebsiella pneumoniae to Escherichia coli in a patient: first case in Europe

Ultrarapid detection of blaKPC₁/₂-₁₂ from perirectal and nasal swabs by use of real-time PCR.

Water soluble extended naphthalene diimides as pH fluorescent sensors and G-quadruplex ligands.