List of works - Tom Wennekes

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

scientific article published on 22 September 2017

A plant-based chemical genomics screen for the identification of flowering inducers.

scientific article published on 3 October 2017

A protein-based pentavalent inhibitor of the cholera toxin B-subunit ⬇️

scientific article published on 2 July 2014

Ambient surface analysis of organic monolayers using direct analysis in real time Orbitrap mass spectrometry.

scientific article

Assessment of partially deoxygenated deoxynojirimycin derivatives as glucosylceramide synthase inhibitors

scientific article published on 7 April 2011

Bacteroides fragilis fucosidases facilitate growth and invasion of Campylobacter jejuni in the presence of mucins ⬇️

scientific article published on 22 August 2020

Chemoenzymatic synthesis of biotin-appended analogues of gangliosides GM2, GM1, GD1a and GalNAc-GD1a for solid-phase applications and improved ELISA tests

scientific article

Corrigendum to "Assessing the oral bioavailability of difluorosialic acid prodrugs, potent viral neuraminidase inhibitors, using a snapshot PK screening assay" [Bioorg. Med. Chem. Lett. 25 (2015) 2505-2509].

scientific article published on 2 July 2016

Detection of Bacterial α-l-Fucosidases with an -Quinone Methide-Based Probe and Mapping of the Probe-Protein Adducts

Development of adamantan-1-yl-methoxy-functionalized 1-deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man

scientific article published on 23 January 2007

Direct imaging of glycans in Arabidopsis roots via click labeling of metabolically incorporated azido-monosaccharides

scientific article

Facile functionalization of peptide nucleic acids (PNAs) for antisense and single nucleotide polymorphism detection

scientific article published on 01 August 2017

Getting a grip on glycans: A current overview of the metabolic oligosaccharide engineering toolbox.

scientific article

Glycosphingolipids and insulin resistance

scientific article published on January 2011

Glycosphingolipids--nature, function, and pharmacological modulation.

scientific article published on January 2009

Glycosylation of Cyclitols: Synthesis of Neamine-Type Aminoglycosides

Hydrolytic and thermal stability of organic monolayers on various inorganic substrates

scientific article published on 13 May 2014

Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors

scientific article published on 17 October 2014

Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2

scientific article

Mechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activity

scientific article

Mechanism-based inhibitors of glycosidases: design and applications.

scientific article

Microwave-assisted formation of organic monolayers from 1-alkenes on silicon carbide

scientific article published on 25 August 2014

Molecular probes: Getting lucky in the lysosome

scientific article published on 01 December 2010

Multivalent glycoconjugates as anti-pathogenic agents ⬇️

scientific article

N-azidoacetylmannosamine-mediated chemical tagging of gangliosides

scientific article published on 27 March 2007

Nanomolar cholera toxin inhibitors based on symmetrical pentavalent ganglioside GM1os-sym-corannulenes.

scientific article published on 04 June 2013

Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity

scientific article

Stability of (bio)functionalized porous aluminum oxide

scientific article published on 28 January 2014

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

scientific article

Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors

scientific article published on 23 October 2015

Synthesis of orthogonally protected 2-deoxystreptamine stereoisomers

The cytosolic β-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation

scientific article

Versatile (bio)functionalization of bromo-terminated phosphonate-modified porous aluminum oxide

scientific article published on 15 May 2015

Versatile Scope of a Masked Aldehyde Nitrone in 1,3-Dipolar Cycloadditions

scientific article published on 2 November 2015

List of works by Tom Wennekes

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

A plant-based chemical genomics screen for the identification of flowering inducers.

A protein-based pentavalent inhibitor of the cholera toxin B-subunit ⬇️

Ambient surface analysis of organic monolayers using direct analysis in real time Orbitrap mass spectrometry.

Assessment of partially deoxygenated deoxynojirimycin derivatives as glucosylceramide synthase inhibitors

Bacteroides fragilis fucosidases facilitate growth and invasion of Campylobacter jejuni in the presence of mucins ⬇️

Chemoenzymatic synthesis of biotin-appended analogues of gangliosides GM2, GM1, GD1a and GalNAc-GD1a for solid-phase applications and improved ELISA tests

Corrigendum to "Assessing the oral bioavailability of difluorosialic acid prodrugs, potent viral neuraminidase inhibitors, using a snapshot PK screening assay" [Bioorg. Med. Chem. Lett. 25 (2015) 2505-2509].

Detection of Bacterial α-l-Fucosidases with an -Quinone Methide-Based Probe and Mapping of the Probe-Protein Adducts

Development of adamantan-1-yl-methoxy-functionalized 1-deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man

Direct imaging of glycans in Arabidopsis roots via click labeling of metabolically incorporated azido-monosaccharides

Facile functionalization of peptide nucleic acids (PNAs) for antisense and single nucleotide polymorphism detection

Getting a grip on glycans: A current overview of the metabolic oligosaccharide engineering toolbox.

Glycosphingolipids and insulin resistance

Glycosphingolipids--nature, function, and pharmacological modulation.

Glycosylation of Cyclitols: Synthesis of Neamine-Type Aminoglycosides

Hydrolytic and thermal stability of organic monolayers on various inorganic substrates

Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors

Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2

Mechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activity

Mechanism-based inhibitors of glycosidases: design and applications.

Microwave-assisted formation of organic monolayers from 1-alkenes on silicon carbide

Molecular probes: Getting lucky in the lysosome

Multivalent glycoconjugates as anti-pathogenic agents ⬇️

N-azidoacetylmannosamine-mediated chemical tagging of gangliosides

Nanomolar cholera toxin inhibitors based on symmetrical pentavalent ganglioside GM1os-sym-corannulenes.

Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity

Stability of (bio)functionalized porous aluminum oxide

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors

Synthesis of orthogonally protected 2-deoxystreptamine stereoisomers

The cytosolic β-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation

Versatile (bio)functionalization of bromo-terminated phosphonate-modified porous aluminum oxide

Versatile Scope of a Masked Aldehyde Nitrone in 1,3-Dipolar Cycloadditions