List of works - Sven Heinz

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

scientific article

Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels

scientific article

Characterization of MAX.3 antigen, a glycoprotein expressed on mature macrophages, dendritic cells and blood platelets: identity with CD84

scientific article published in 2000

Combining TSS-MPRA and sensitive TSS profile dissimilarity scoring to study the sequence determinants of transcription initiation

scientific article published on 5 July 2023

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

scientific article

Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages

article published in the Proceedings of the National Academy of Sciences of the United States of America

Effect of natural genetic variation on enhancer selection and function.

scientific article published on 13 October 2013

Exploiting genomics and natural genetic variation to decode macrophage enhancers

scientific article

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

scientific article

Genome evolution in the allotetraploid frog Xenopus laevis

scientific article

Genomic organization of the human gene HEP27: alternative promoter usage in HepG2 cells and monocyte-derived dendritic cells

scientific article

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

scientific article

Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer.

scientific article published on 31 May 2018

Human promoters are intrinsically directional

scientific article

Identification and dynamic quantification of regulatory elements using total RNA

scientific article published on 24 October 2019

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter

scientific article

Macrophage development from HSCs requires PU.1-coordinated microRNA expression.

scientific article published on 5 July 2011

Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.

scientific article

Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.

scientific article published on 13 March 2017

Perspectives on Unidirectional versus Divergent Transcription

scientific article published in November 2015

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

scientific article published on August 2013

Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells

scientific article

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

scientific article published on 02 June 2013

Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies

scientific article published on January 2012

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

scientific article

Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages

scientific article

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

scientific article

Species-specific regulation of Toll-like receptor 3 genes in men and mice.

scientific article published on 2 April 2003

The selection and function of cell type-specific enhancers

scientific article

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.

scientific article

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models

scientific article published on 01 December 2020

Transcription Elongation Can Affect Genome 3D Structure

scientific article published on 23 August 2018

Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor

scientific article

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

scientific article

List of works by Sven Heinz

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels

Characterization of MAX.3 antigen, a glycoprotein expressed on mature macrophages, dendritic cells and blood platelets: identity with CD84

Combining TSS-MPRA and sensitive TSS profile dissimilarity scoring to study the sequence determinants of transcription initiation

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages

Effect of natural genetic variation on enhancer selection and function.

Exploiting genomics and natural genetic variation to decode macrophage enhancers

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

Genome evolution in the allotetraploid frog Xenopus laevis

Genomic organization of the human gene HEP27: alternative promoter usage in HepG2 cells and monocyte-derived dendritic cells

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer.

Human promoters are intrinsically directional

Identification and dynamic quantification of regulatory elements using total RNA

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter

Macrophage development from HSCs requires PU.1-coordinated microRNA expression.

Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.

Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.

Perspectives on Unidirectional versus Divergent Transcription

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Species-specific regulation of Toll-like receptor 3 genes in men and mice.

The selection and function of cell type-specific enhancers

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models

Transcription Elongation Can Affect Genome 3D Structure

Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells