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List of works by Bernhard Gentner

A double-switch vector system positively regulates transgene expression by endogenous microRNA expression (miR-ON vector).

scientific article published on 26 February 2013

A microRNA-based system for selecting and maintaining the pluripotent state in human induced pluripotent stem cells

scientific article

A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice.

scientific article published on 13 March 2013

Attenuation of miR-126 activity expands HSC in vivo without exhaustion.

scientific article

Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy

scientific article

Dual-regulated lentiviral vector for gene therapy of X-linked chronic granulomatosis.

scientific article published on 29 May 2014

Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche.

scientific article

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy

scientific article published on 13 March 2017

Elderly patients > 65 years of age with acute myeloid leukemia and normal karyotype benefit from intensive therapeutic programs

scientific article published on 13 April 2016

Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state

scientific article published on 16 November 2007

Engineered tumor-infiltrating macrophages as gene delivery vehicles for interferon-α activates immunity and inhibits breast cancer progression.

scientific article published on 29 April 2014

Exploiting microRNA regulation for genetic engineering ⬇️

scientific article published on November 1, 2012

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

scientific article

Genetic testing for germline mutations of the APC gene in patients with apparently sporadic desmoid tumors but a family history of colorectal carcinoma.

scientific article

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

scientific article published on 12 December 2017

Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy

scientific article published in November 2010

Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response.

scientific article published on 26 July 2016

Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells.

scientific article published on 30 June 2017

MicroRNA-124 is a subventricular zone neuronal fate determinant.

scientific article published on June 2012

MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy

scientific article published on 6 October 2011

MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia.

scientific article published on 8 July 2015

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

scientific article

Neonatal umbilical cord blood transplantation halts skeletal disease progression in the murine model of MPS-I.

scientific article published on 25 August 2017

Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerixafor alone.

scientific article published on 29 December 2016

Rapid detection of retroviral vector integration sites in colony-forming human peripheral blood progenitor cells using PCR with arbitrary primers

scientific article published on May 2003

Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform

scientific article published on 17 March 2009

Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells

scientific article published on 7 November 2002

Stable knockdown of microRNA in vivo by lentiviral vectors

scientific article

Targeted genome editing in human repopulating haematopoietic stem cells

scientific article published on 28 May 2014

Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.

scientific article

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors

scientific article

[A case of attenuated familial adenomatous polyposis coli (AFAP)]

scientific article

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

scientific article published on 20 January 2016

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.

scientific article published on April 2016

miRNA-126 Orchestrates an Oncogenic Program in B Cell Precursor Acute Lymphoblastic Leukemia

scientific article published in June 2016

microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons

scientific article published on 05 March 2014

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