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List of works by Edwin Bremer

A CD47-blocking TRAIL fusion protein with dual pro-phagocytic and pro-apoptotic anticancer activity.

scientific article published on 26 October 2013

A better TRAIL variant for tumor cell-specific targeting? - letter

scientific article published on 05 October 2010

A novel AML-selective TRAIL fusion protein that is superior to Gemtuzumab Ozogamicin in terms of in vitro selectivity, activity and stability

scientific article published on 5 March 2009

Antibody-based fusion proteins to target death receptors in cancer.

scientific article published on 06 January 2011

Bifunctional antibody fragment-based fusion proteins for the targeted elimination of pathogenic T-cell subsets

scientific article published in January 2014

C-type lectin-like molecule-1 (CLL1)-targeted TRAIL augments the tumoricidal activity of granulocytes and potentiates therapeutic antibody-dependent cell-mediated cytotoxicity

scientific article

CD20(+) T cells have a predominantly Tc1 effector memory phenotype and are expanded in the ascites of patients with ovarian cancer

scientific article

CD20+inflammatory T-cells are present in blood and brain of multiple sclerosis patients and can be selectively targeted for apoptotic elimination

scientific article published on 12 June 2014

Calreticulin, a therapeutic target?

scientific article published on 9 March 2016

Carbon monoxide-releasing molecule-2 (CORM-2) attenuates acute hepatic ischemia reperfusion injury in rats

scientific article published on 5 May 2010

Cell surface delivery of TRAIL strongly augments the tumoricidal activity of T cells

scientific article published on 13 July 2011

Direct and Indirect Rituximab-Induced T Cell Depletion: Comment on the Article by Mélet et al

scientific article published on 01 April 2014

Editorial: Endoplasmic Reticulum and Its Role in Tumor Immunity

scientific article published on 17 November 2015

Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity.

scientific article published on 11 February 2014

EpCAM in morphogenesis.

scientific article published on May 2008

EpCAM-targeted induction of apoptosis.

scientific article published on May 2008

Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cells

scientific article

Galectin-9 activates and expands human T-helper 1 cells.

scientific article

Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity.

scientific article

Melanoma-Directed Activation of Apoptosis Using a Bispecific Antibody Directed at MCSP and TRAIL Receptor-2/Death Receptor-5.

scientific article published on 2 December 2015

Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanoma outgrowth in vitro and in vivo

scientific article published on 23 November 2010

Potent systemic anticancer activity of adenovirally expressed EGFR-selective TRAIL fusion protein

scientific article published on 23 September 2008

Review: on TRAIL for malignant glioma therapy?

scientific article published on 20 January 2010

Selective elimination of pathogenic synovial fluid T-cells from rheumatoid arthritis and juvenile idiopathic arthritis by targeted activation of Fas-apoptotic signaling

scientific article published on 15 April 2011

Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein

scientific article published on 31 July 2007

Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with speci

scientific article

Superior activity of fusion protein scFvRit:sFasL over cotreatment with rituximab and Fas agonists

scientific article

Target cell-restricted and -enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma-associated antigen EGP2.

scientific article published in March 2004

Targeted delivery of CD40L promotes restricted activation of antigen-presenting cells and induction of cancer cell death

scientific article published on 17 April 2014

Targeted delivery of a designed sTRAIL mutant results in superior apoptotic activity towards EGFR-positive tumor cells

scientific article

Targeted elimination of activated hepatic stellate cells by an anti-epidermal growth factor-receptor single chain fragment variable antibody-tumor necrosis factor-related apoptosis-inducing ligand (scFv425-sTRAIL).

scientific article

Targeted induction of apoptosis for cancer therapy: current progress and prospects.

scientific article published on 23 June 2006

Targeting of the tumor necrosis factor receptor superfamily for cancer immunotherapy

scientific article published on 11 June 2013

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux

scientific article

The ever-expanding immunomodulatory role of calreticulin in cancer immunity

scientific article

The histone deacetylase inhibitor valproic acid potently augments gemtuzumab ozogamicin-induced apoptosis in acute myeloid leukemic cells

scientific article published on 23 November 2006

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