List of works by Anna Linda Zignego

"Inapparent" hepatitis B virus infection and hepatitis C virus replication in alcoholic subjects with and without liver disease

scientific article published in March 1994

A phase II, single-arm multicenter study of low-dose rituximab for refractory mixed cryoglobulinemia secondary to hepatitis C virus infection

scientific article published on 5 May 2011

Amplification of hepatitis delta virus RNA sequences by polymerase chain reaction: a tool for viral detection and cloning

scientific article published in February 1990

Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV-associated lymphoproliferative disorders.

scientific article

Anti-TNF-α therapy prevents the recurrence of joint bleeding in haemophilia and arthritis

scientific article published on 17 October 2013

Anti-hepatitis A virus seroprevalence and seroconversion in a cohort of patients with chronic viral hepatitis

scientific article published in September 2002

Association between mixed cryoglobulinemia, translocation (14;18), and persistence of occult HCV lymphoid infection after treatment

scientific article published in May 2006

Association between persistent lymphatic infection by hepatitis C virus after antiviral treatment and mixed cryoglobulinemia

scientific article published in March 2008

Association of t(14;18) translocation with HCV infection in gastrointestinal MALT lymphomas.

scientific article published on 16 May 2008

B-cells and mixed cryoglobulinemia.

scientific article published on 28 March 2007

Chemokine (CXC motif) ligand 9 serum levels in mixed cryoglobulinaemia are associated with circulating levels of IFN-gamma and TNF-alpha.

scientific article published in November 2012

Chronic hepatitis C and B-cell non-Hodgkin's lymphoma

scientific article published on February 1996

Chronic viral hepatitis induced by hepatitis C but not hepatitis B virus infection correlates with increased liver angiogenesis

scientific article published in January 1997

Clinical epidemiology of chronic viral hepatitis B: A Tuscany real-word large-scale cohort study.

scientific article published in May 2018

Correction: Real-life data on potential drug-drug interactions in patients with chronic hepatitis C viral infection undergoing antiviral therapy with interferon-free DAAs in the PITER Cohort Study

scientific article published on 2 January 2018

Cryoglobulinaemia

scientific article published on 02 August 2018

Cryoglobulinemic membranoproliferative glomerulonephritis associated with hepatitis C virus

scientific article published in January 1993

Current and future challenges in HCV: insights from an Italian experts panel

scientific article published on 2 November 2017

Deregulation of microRNA expression in peripheral blood mononuclear cells from patients with HCV-related malignancies

scientific article

Different biochemical patterns in type II and type III mixed cryoglobulinemia in HCV positive patients

scientific article published in September 2018

Direct antiviral agents for treatment-naïve patients with genotype 1 hepatitis C: A statistical model for comparing outcomes between real world and clinical trials

scientific article published on 2 July 2015

Editorial: interferon-free DAAs are a great boon for patients with hepatitis C and cryoglobulinaemia-Authors' reply

scientific article published on 01 October 2018

Effect of alpha-interferon on hepatitis C virus chronic infection in mixed cryoglobulinemia patients ⬇️

scientific article published on March 1, 1993

Effect of antiviral treatment in patients with chronic HCV infection and t(14;18) translocation

scientific article published on 10 April 2003

Effect of chronic hepatitis C virus infection on inflammatory lipid mediators

scientific article published in September 2007

Efficacy and safety of Boceprevir-based therapy in HCVG1 treatment-experienced patients with advanced fibrosis/cirrhosis: Italian NPP survey

article

Efficacy and safety of peginterferon alfa-2b plus ribavirin for HCV-positive mixed cryoglobulinemia: a multicentre open-label study

scientific article published in November 2011

Efficacy of low-dose rituximab for the treatment of mixed cryoglobulinemia vasculitis: Phase II clinical trial and systematic review

scientific article published on 29 May 2015

Elevated Serum Levels of Osteopontin in HCV-Associated Lymphoproliferative Disorders.

scientific article published on 10 November 2005

Epidemiological, demographic and clinical data on chronic viral hepatitis C in Tuscany

scientific article published on 26 June 2018

Erectile dysfunction and hepatitis C virus infection

scientific article published in August 2002

Etiopathogenetic role of hepatitis C virus in mixed cryoglobulinemia, chronic liver diseases and lymphomas

scientific article

Evidence-based recommendations on the management of extrahepatic manifestations of chronic hepatitis C virus infection

scientific article published on 17 February 2017

Exacerbation of peripheral neuropathy during alpha-interferon therapy in a patient with mixed cryoglobulinemia and hepatitis B virus infection

scientific article published in September 1996

Extrahepatic manifestations of HCV infection: facts and controversies

scientific article

Extrahepatic manifestations of Hepatitis C Virus infection: a general overview and guidelines for a clinical approach

scientific article

Extrahepatic manifestations of chronic hepatitis C virus infection.

scientific article

Forecasting Hepatitis C liver disease burden on real-life data. Does the hidden iceberg matter to reach the elimination goals?

Forecasting liver disease burden

Free light chains: Eclectic multipurpose biomarker

scientific article published on 17 September 2017

From meetings

Gender Differences in HCV Chronic Liver Disease: A Real Life Evaluation in Piter (Piattaforma Italiana per Lo Studio Della Terapia Delle Epatiti Virali) Cohort Study

Genetic determinants in hepatitis C virus-associated mixed cryoglobulinemia: role of polymorphic variants of BAFF promoter and Fcγ receptors

scientific article published in May 2011

Genetic insights into the disease mechanisms of type II mixed cryoglobulinemia induced by hepatitis C virus.

scientific article published on September 2007

HBV and HCV chronic infection: autoimmune manifestations and lymphoproliferation

scientific article published on December 2008

HCV and cryoglobulinemic vasculitis.

scientific article

HCV and lymphoproliferation

scientific article published on 19 July 2012

HCV infection facilitates asymptomatic carotid atherosclerosis: preliminary report of HCV RNA localization in human carotid plaques.

scientific article published in September 2007

HCV patients, psychopathology and tryptophan metabolism: analysis of the effects of pegylated interferon plus ribavirin treatment

scientific article published in September 2007

HCV-Related Rheumatic Manifestations and Therapeutic Strategies

scientific article published on 06 September 2015

HCV-related autoimmune and neoplastic disorders: the HCV syndrome

scientific article published on September 2007

HCV-related cryoglobulinemic vasculitis: an update on its etiopathogenesis and therapeutic strategies

scientific article published on November 2003

HCV-related liver and lymphoproliferative diseases: association with polymorphisms of IL28B and TLR2.

scientific article published on 11 May 2016

HCV-related mixed cryoglobulinemia: Data from PITER, a nationwide Italian HCV cohort study

article

HCV-unrelated cryoglobulinaemic vasculitis: the results of a prospective observational study by the Italian Group for the Study of Cryoglobulinaemias (GISC).

scientific article published on March 2017

HCV–Related Mixed Cryoglobulinemia: Data from Piter, a Nationwide Italian HCV Cohort Study

article

Hepatitis C virus (HCV) in cryoglobulinaemic leukocytoclastic vasculitis (LCV): could the presence of HCV in skin lesions be related to T CD8+ lymphocytes, HLA-DR and ICAM-1 expression?

scientific article published on December 1999

Hepatitis C virus (HCV) infection: a systemic disease.

scientific article

Hepatitis C virus RNA localization in human carotid plaques

scientific article published on 5 November 2009

Hepatitis C virus and mixed cryoglobulinaemia

scientific article published in March 1994

Hepatitis C virus and type 1 diabetes

scientific article published on September 2013

Hepatitis C virus as a lymphotropic agent: evidence and pathogenetic implications.

scientific article

Hepatitis C virus chronic infection as a common cause of mixed cryoglobulinaemia and autoimmune liver disease

scientific article published in July 1994

Hepatitis C virus core protein enhances B lymphocyte proliferation

scientific article published in September 2007

Hepatitis C virus core protein expression in human B-cell lines does not significantly modify main proliferative and apoptosis pathways

scientific article published on July 2002

Hepatitis C virus genotype analysis in patients with type II mixed cryoglobulinemia

scientific article

Hepatitis C virus in mixed cryoglobulinemia and B cell lymphoma.

scientific article published in January 1994

Hepatitis C virus infection and B-cell lymphomas

scientific article published in January 1994

Hepatitis C virus infection and arthritis. A clinico-serological investigation of arthritis in patients with or without cryoglobulinemic syndrome

scientific article

Hepatitis C virus infection and cutaneous vasculitis in mixed cryoglobulinemia

scientific article

Hepatitis C virus infection in mixed cryoglobulinemia and B-cell non-Hodgkin's lymphoma: evidence for a pathogenetic role

scientific article published on January 1997

Hepatitis C virus infection in patients with non-Hodgkin's lymphoma

scientific article published in October 1994

Hepatitis C virus infection in the immunocompromised host: a complex scenario with variable clinical impact

scientific article

Hepatitis C virus infection of mononuclear cells from peripheral blood and liver infiltrates in chronically infected patients

scientific article published in September 1995

Hepatitis C virus lymphotropism: lessons from a decade of studies.

scientific article published on September 2007

Hepatitis C virus persistence in human hematopoietic cells injected into SCID mice

scientific article published on July 1998

Hepatitis C virus-related autoimmunity in patients with porphyria cutanea tarda

scientific article

Hepatitis C virus-related lymphoproliferative disorders: an overview.

scientific article

Hepatitis C virus-related mixed cryoglobulinemia: is genetics to blame?

scientific article published on December 2013

Hepatitis C-associated B-cell non-Hodgkin lymphomas: the emerging role of miRNA-26b.

scientific article published on 24 August 2013

Hepatitis-C-virus infection and cancer

scientific article published in June 1997

Hepatocellular carcinoma in mixed cryoglobulinemia patients.

scientific article

Hepatotropic viruses: new insights in pathogenesis and treatment

scientific article published on January 2008

High circulating chemokines (C-X-C motif) ligand 9, and (C-X-C motif) ligand 11, in hepatitis C-associated cryoglobulinemia

scientific article

High levels of circulating N-terminal pro-brain natriuretic peptide in patients with hepatitis C.

scientific article published in December 2010

IgG3 subclass: A possible trigger of mixed cryoglobulin cascade in hepatitis C virus chronic infection

scientific article published on 24 June 2017

Impaired response to alpha interferon in patients with an inapparent hepatitis B and hepatitis C virus coinfection

scientific article published in January 1997

Improvement in liver cirrhosis after treatment of HCV-related mixed cryoglobulinemia with rituximab

scientific article published on 01 September 2007

Incidence of DAA failure and the clinical impact of retreatment in real-life patients treated in the advanced stage of liver disease: Interim evaluations from the PITER network

scientific article published on 4 October 2017

Infection of peripheral blood mononuclear cells by hepatitis C virus in mixed cryoglobulinemia

scientific article published in December 1993

Infection of peripheral mononuclear blood cells by hepatitis C virus

scientific article published on July 1, 1992

Interferon and thymosin combination therapy in naive patients with chronic hepatitis C: preliminary results

scientific article published on October 1998

Interferon lambda 3 rs12979860 polymorphism in patients with haemophilia and HCV infection: a predictor of spontaneous viral clearance and sustained virological response.

scientific article published on 13 February 2014

Interferon-alpha in mixed cryoglobulinemia patients: a randomized, crossover-controlled trial

scientific article published in March 1993

Interferon-free therapy in hepatitis C virus mixed cryoglobulinaemia: a prospective, controlled, clinical and quality of life analysis

scientific article published on 28 June 2018

International diagnostic guidelines for patients with HCV-related extrahepatic manifestations. A multidisciplinary expert statement

scientific article published on 15 September 2016

International therapeutic guidelines for patients with HCV-related extrahepatic disorders. A multidisciplinary expert statement

scientific article published on 7 March 2017

Interstitial lung fibrosis and rheumatic disorders in patients with hepatitis C virus infection.

scientific article published on March 1997

Involvement of PI3K in HCV-related lymphoproliferative disorders

scientific article

JH6 Gene Usage among HCV-Associated MALT Lymphomas Harboring t(14;18) Translocation

article

Lack of preferential localization of tumoral mass in B-cell non-Hodgkin's lymphoma associated with hepatitis C virus infection.

scientific article published on April 1997

Latent hepatitis B virus (HBV) infection in systemic necrotizing vasculitis

scientific article published on January 1991

Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis

scientific article published on 01 May 2007

Long course and prognostic factors of virus-induced cirrhosis of the liver

scientific article

Long-lasting persistence of large B-cell clones in hepatitis C virus-cured patients with complete response of mixed cryoglobulinaemia vasculitis

scientific article published on 15 February 2019

Long-term effect of HCV eradication in patients with mixed cryoglobulinemia: a prospective, controlled, open-label, cohort study

scientific article published on 10 February 2015

Longitudinal assessment of liver stiffness in patients undergoing antiviral treatment for hepatitis C.

scientific article published on 7 May 2013

Longitudinal evaluation of liver stiffness and outcomes in patients with chronic hepatitis C before and after short- and long-term IFN-free antiviral treatment

scientific article published on 21 November 2019

Low serum tryptophan levels, reduced macrophage IDO activity and high frequency of psychopathology in HCV patients.

scientific article

Lymphotropic Virus Infection of Peripheral Blood Mononuclear Cells in B-Cell Non-Hodgkin’s Lymphoma ⬇️

scientific article published on January 1, 1997

Management of hepatitis C virus infection in patients with chronic kidney disease: position statement of the joint committee of Italian association for the study of the liver (AISF), Italian society of internal medicine (SIMI), Italian society of inf

Management of hepatitis C virus infection in patients with chronic kidney disease: position statement of the joint committee of Italian association for the study of the liver (AISF), Italian society of internal medicine (SIMI), Italian society of inf

MicroRNA expression in hepatitis C virus-related malignancies: A brief review

scientific article (publication date: 28 July 2015)

Mixed cryoglobulinaemia: An important but frequently unrecognized and underestimated HCV-related condition in the real life practice

scientific article

Modifications of plasma platelet-activating factor (PAF)-acetylhydrolase/PAF system activity in patients with chronic hepatitis C virus infection

scientific article published in January 2007

Non-Hodgkin's lymphoma: possible role of hepatitis C virus

scientific article published in August 1994

Notch4 and mhc class II polymorphisms are associated with hcv-related benign and malignant lymphoproliferative diseases

scientific article published on 6 May 2017

Nucleotide sequence analysis of three different hepatitis delta viruses isolated from a woodchuck and humans.

scientific article published in March 1991

Ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir, plus ribavirin for patients with hepatitis C virus genotype 1 or 4 infection with cirrhosis (ABACUS): a prospective observational study

scientific article published on 10 April 2017

PDCD1 and IFNL4 genetic variants and risk of developing hepatitis C virus-related diseases

scientific article published on 16 September 2020

Parallel increase of circulating CXCL11 and CXCL10 in mixed cryoglobulinemia, while the proinflammatory cytokine IL-6 is associated with high serum Th2 chemokine CCL2.

scientific article published on 5 April 2013

Patterns and mechanisms of hepatitis B/hepatitis D reinfection after liver transplantation.

scientific article

Pegylated interferon alfa-2b plus ribavirin in the retreatment of interferon-ribavirin nonresponder patients

scientific article published on April 2006

Pegylated interferon α plus ribavirin for the treatment of chronic hepatitis C: a multicentre independent study supported by the Italian Drug Agency

scientific article published on 28 June 2014

Persistent hepatitis B virus infection of mononuclear blood cells without concomitant liver infection. The liver transplantation model.

scientific article published on June 1990

Polymyositis, lung fibrosis, and cranial neuropathy in a patient with hepatitis C virus infection

scientific article published in June 1996

Preliminary classification criteria for the cryoglobulinaemic vasculitis

scientific article

Prevalence of ANCA in mixed cryoglobulinemia and chronic hepatitis C virus infection

scientific article published in November 2003

Prevalence of bcl-2 rearrangement in patients with hepatitis C virus-related mixed cryoglobulinemia with or without B-cell lymphomas

scientific article published in October 2002

Prevalence of mixed infection by different hepatitis C virus genotypes in patients with hepatitis C virus-related chronic liver disease

scientific article published in July 1999

Prevalence of monoclonal gammopathies in patients with hepatitis C virus infection

scientific article published on August 1998

Real life experiences in HCV management in 2018

scientific article published on 15 January 2019

Real-life data on potential drug-drug interactions in patients with chronic hepatitis C viral infection undergoing antiviral therapy with interferon-free DAAs in the PITER Cohort Study

scientific article

Recommendations for the management of mixed cryoglobulinemia syndrome in hepatitis C virus-infected patients

scientific article published on 15 February 2011

Reducing the price of new hepatitis C drugs in the Tuscany region of Italy

scientific article published on 24 June 2015

Relevance of inapparent coinfection by hepatitis B virus in alpha interferon-treated patients with hepatitis C virus chronic hepatitis

scientific article published on April 1997

Retreatment regimen of rituximab monotherapy given at the relapse of severe HCV-related cryoglobulinemic vasculitis: Long-term follow up data of a randomized controlled multicentre study

scientific article

Role of the HLA class II: HCV-related disorders.

scientific article published in June 2007

Serotonin and its implication in the side-effects of interferon-based treatment of patients with chronic viral hepatitis: Pharmacological interventions

scientific article published on 24 April 2013

Serum HCV-RNA and liver histologic findings in patients with long-term normal transaminases

scientific article published on August 1, 1997

Serum hepatitis delta virus RNA in patients with delta hepatitis and in liver graft recipients

scientific article published in July 1990

Serum markers of hepatitis B virus and anti-delta antibody in chronic liver disease

scientific article published in December 1985

Sofosbuvir/Velpatasvir for the treatment of Hepatitis C Virus infection

scientific article published on 8 October 2018

T(14;18) translocation in chronic hepatitis C virus infection

scientific article published in February 2000

The hepatitis C virus infection as a systemic disease

scientific article published on October 2012

The liver-cytokine-brain circuit in interferon-based treatment of patients with chronic viral hepatitis

scientific article

Transient elastography for the assessment of liver fibrosis in patients with chronic viral hepatitis: the missing tool?

scientific article published on 23 May 2009

Treatment of HCV-Related Mixed Cryoglobulinemia

scientific article published on 25 August 2015

Treatment with rituximab in patients with mixed cryoglobulinemia syndrome: results of multicenter cohort study and review of the literature

scientific article published on 24 July 2011

Triple antiviral therapy in hepatitis C virus infection with or without mixed cryoglobulinaemia: a prospective, controlled pilot study

scientific article published on 19 June 2014

Type C chronic hepatitis complicated by B-cell lymphoma

scientific article published in November 1995

Validation of the classification criteria for cryoglobulinaemic vasculitis

scientific article published on 3 July 2014

Value of IL28B genotyping in patients with HCV-related mixed cryoglobulinemia: results of a large, prospective study.

scientific article

Viral liver cirrhosis: natural course, pathogenesis and clinical implications of the complications

scientific article

Viruses and cancers: possible role of hepatitis C virus

scientific article published on September 1997

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