List of works by Andrew D McAinsh

Bod1, a novel kinetochore protein required for chromosome biorientation

scientific article

Building an integrated model of chromosome congression

scientific article

CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes

scientific article published on 01 May 2020

Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase

scientific article published on 27 February 2014

Cell transformation disrupts the efficiency of chromosome segregation through microtubule detyrosination

Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways

scientific article

Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments.

scientific article

Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment

scientific article

DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p

scientific article published in September 1999

Distribution of the voltage-dependent calcium channel alpha(1A) subunit throughout the mature rat brain and its relationship to neurotransmitter pathways

scientific article published in July 1998

Dual pathway spindle assembly increases both the speed and the fidelity of mitosis

scientific article published on 24 October 2011

Dynamics of CENP-N kinetochore binding during the cell cycle

scientific article

Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors

scientific article published on 01 April 2020

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

scientific article

Exotic mitotic mechanisms

scientific article published on 05 December 2012

Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes

scientific article

How Kinetochores CCAN resist force

scientific article published in September 2014

Human kinetochores are swivel joints that mediate microtubule attachments.

scientific article published on 3 September 2016

Hydrodynamic analysis of human kinetochore complexes during mitosis

scientific article published in January 2009

Inferring the Forces Controlling Metaphase Kinetochore Oscillations by Reverse Engineering System Dynamics

scientific article published on 30 November 2015

KNL1-Bubs and RZZ Provide Two Separable Pathways for Checkpoint Activation at Human Kinetochores

scientific article published on December 2015

KiT: a MATLAB package for kinetochore tracking

scientific article

Kif15 functions as an active mechanical ratchet.

scientific article published on 17 May 2018

Kinesin-12 motors cooperate to suppress microtubule catastrophes and drive the formation of parallel microtubule bundles

scientific article

Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases

scientific article

Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly

scientific article published on February 2009

Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells.

scientific article published on 13 November 2017

MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

scientific article

Mechanochemical cell biology

scientific article published on 07 October 2011

Mitotic live-cell imaging at different timescales

scientific article published on 01 January 2018

Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster

scientific article

Molecular control of kinetochore-microtubule dynamics and chromosome oscillations

scientific article

Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation

scientific article published in April 2017

Nonautonomous movement of chromosomes in mitosis

scientific article published in October 2013

Photoactivatable-GFP-α-tubulin as a tool to study microtubule plus-end turnover in living human cells

scientific article

Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins

scientific article

Prime movers: the mechanochemistry of mitotic kinesins

scientific article published on April 2014

Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion

scientific article

Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

scientific article published on 30 August 2018

Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair

scientific article

Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing

scientific article

Single molecule mechanics reveal Kif15 as an active molecular ratchet with acute strain sensitivity

Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension

scientific article

Spindle centricity

scientific article published on 01 December 2011

Springs, clutches and motors: driving forward kinetochore mechanism by modelling

scientific article published on April 2011

Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex

scientific article

Structure, Function, and Regulation of Budding Yeast Kinetochores ⬇️

scientific article published on January 1, 2003

Super-resolution kinetochore tracking reveals the mechanisms of human sister kinetochore directional switching

scientific article published on 13 October 2015

The CCAN complex: linking centromere specification to control of kinetochore-microtubule dynamics

scientific article published on 19 October 2011

The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity

scientific article

The Enterohemorrhagic Escherichia coli Effector EspW Triggers Actin Remodeling in a Rac1-Dependent Manner

scientific article published on 19 June 2017

The Kinesin-12 Kif15 is a processive track-switching tetramer

scientific article published on 25 March 2014

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

scientific article

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism.

scientific article published on 10 May 2009

Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities

scientific article published on 30 December 2015

Walking, hopping, diffusing and braking modes of kinesin-5.

scientific article

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