List of works - Dongyun Yang

A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials

scientific article published on 04 October 2016

A phase I/II trial of vorinostat in combination with 5-fluorouracil in patients with metastatic colorectal cancer who previously failed 5-FU-based chemotherapy

scientific article

ABCB1, SLCO1B1 and UGT1A1 gene polymorphisms are associated with toxicity in metastatic colorectal cancer patients treated with first-line irinotecan

scientific article

AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth

scientific article published on 15 January 2016

An individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrence

scientific article

Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence.

scientific article published on 2 July 2013

Association of variants in genes encoding for macrophage-related functions with clinical outcome in patients with locoregional gastric cancer.

scientific article

Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials.

scientific article published on 24 March 2017

Biomarkers for Cetuximab-Based Neoadjuvant Radiochemotherapy in Locally Advanced Rectal Cancer

scientific article published on 10 May 2011

CXCR4 polymorphism predicts progression-free survival in metastatic colorectal cancer patients treated with first-line bevacizumab-based chemotherapy

scientific article published on 9 August 2016

Cell cycle regulators are critical for maintaining the differentiation potential and immaturity in adipogenesis of adipose-derived stem cells

scientific article published on 20 July 2011

Clinical Significance of TLR1 I602S Polymorphism for Patients with Metastatic Colorectal Cancer Treated with FOLFIRI plus Bevacizumab

scientific article published on 11 May 2016

Clinical relevance of EMT and stem-like gene expression in circulating tumor cells of metastatic colorectal cancer patients.

scientific article published on 9 August 2016

Combined assessment of EGFR-related molecules to predict outcome of 1st-line cetuximab-containing chemotherapy for metastatic colorectal cancer

scientific article published on 22 April 2016

Common cancer stem cell gene variants predict colon cancer recurrence.

scientific article published on 14 September 2011

Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab

scientific article published in July 2006

Cytokeratin-20 and Survivin-Expressing Circulating Tumor Cells Predict Survival in Metastatic Colorectal Cancer Patients by a Combined Immunomagnetic qRT-PCR Approach

scientific article

Drug abuse prevention program development. Results among Latino and non-Latino white adolescents

scientific article published in December 2003

Expression of Genes Involved in Vascular Morphogenesis and Maturation Predicts Efficacy of Bevacizumab-Based Chemotherapy in Patients Undergoing Liver Resection.

scientific article

FCGR polymorphisms and cetuximab efficacy in chemorefractory metastatic colorectal cancer: an international consortium study.

scientific article published on 10 July 2014

GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.

scientific article

Gender-related survival differences associated with EGFR polymorphisms in metastatic colon cancer

scientific article

Gender-related survival differences associated with polymorphic variants of estrogen receptor-β (ERβ) in patients with metastatic colon cancer.

scientific article

Gender-specific genomic profiling in metastatic colorectal cancer patients treated with 5-fluorouracil and oxaliplatin.

scientific article published on January 2011

Gender-specific profiling in SCN1A polymorphisms and time-to-recurrence in patients with stage II/III colorectal cancer treated with adjuvant 5-fluoruracil chemotherapy.

scientific article published on 11 June 2013

Gene expression in tumor-adjacent normal tissue is associated with recurrence in patients with rectal cancer treated with adjuvant chemoradiation

scientific article

Gene expression levels of epidermal growth factor receptor, survivin, and vascular endothelial growth factor as molecular markers of lymph node involvement in patients with locally advanced rectal cancer

scientific article

Generation of a concise gene panel for outcome prediction in urinary bladder cancer

scientific article

Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer.

scientific article published on 29 July 2014

Genetic variants associated with colorectal brain metastases susceptibility and survival.

scientific article published on 22 December 2015

Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer.

scientific article

Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer

scientific article

Genetic variations in angiogenesis pathway genes associated with clinical outcome in localized gastric adenocarcinoma.

scientific article published on 21 July 2009

Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus

scientific article published in May 2010

Genetic variations in angiopoietin and pericyte pathways and clinical outcome in patients with resected colorectal liver metastases.

scientific article published on 17 February 2015

Genetic variations in immunomodulatory pathways to predict survival in patients with locoregional gastric cancer.

scientific article published on 31 May 2016

Genomic profiling associated with recurrence in patients with rectal cancer treated with chemoradiation.

scientific article

Germline Polymorphisms in Genes Involved in the IGF1 Pathway Predict Efficacy of Cetuximab in Wild-type KRAS mCRC Patients ⬇️

scientific article published on October 8, 2010

Germline polymorphisms in genes involved in the CD44 signaling pathway are associated with clinical outcome in localized gastric adenocarcinoma ⬇️

scientific article published on February 11, 2011

Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer.

scientific article published on 15 September 2015

Impact of access to NCI- and NCCN-designated cancer centers on outcomes for multiple myeloma patients: A SEER registry analysis

scientific article published on 13 November 2015

Impact of sex on the survival of patients with hepatocellular carcinoma: a Surveillance, Epidemiology, and End Results analysis.

scientific article published on 31 July 2014

Impact of sex, age, and ethnicity/race on the survival of patients with rectal cancer in the United States from 1988 to 2012.

scientific article published on 19 July 2016

Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagus.

scientific article

Influence of sex on the survival of patients with esophageal cancer.

scientific article

Insulin-like growth factor receptor polymorphism defines clinical outcome in estrogen receptor-positive breast cancer patients treated with tamoxifen.

scientific article published on 5 March 2013

Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer

scientific article published on 9 December 2014

Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis.

scientific article

Interleukin-8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models.

scientific article published on May 2011

Intratumoral COX-2 gene expression is a predictive factor for colorectal cancer response to fluoropyrimidine-based chemotherapy

scientific article published in May 2005

Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).

scientific article published on 5 June 2012

Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer.

scientific article published on 22 May 2011

Metastatic Colorectal Cancer in Hispanics: Treatment Outcomes in a Treated Population

scientific article

Molecular determinants of irinotecan efficacy.

scientific article

Outcome disparities among ethnic subgroups of Waldenström's macroglobulinemia: a population-based study

scientific article published on 4 June 2014

Outcome disparities in multiple myeloma: a SEER-based comparative analysis of ethnic subgroups

scientific article published on 26 April 2012

Persistent Disparities Among Patients With T-Cell Non-Hodgkin Lymphomas and B-Cell Diffuse Large Cell Lymphomas Over 40 Years: A SEER Database Review.

scientific article published on 19 June 2015

Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer

scientific article published on 6 April 2010

Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia

scientific article published in January 2008

Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer

scientific article

Physical activity and breast cancer risk among Asian-American women in Los Angeles: a case-control study

scientific article published in May 2003

Plastin polymorphisms predict gender- and stage-specific colon cancer recurrence after adjuvant chemotherapy.

scientific article published on 29 October 2013

Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer

scientific article

Polymorphisms in cyclooxygenase-2 and epidermal growth factor receptor are associated with progression-free survival independent of K-ras in metastatic colorectal cancer patients treated with single-agent cetuximab

scientific article

Polymorphisms in immunoregulatory genes, smoky coal exposure and lung cancer risk in Xuan Wei, China.

scientific article published on 14 March 2007

Polymorphisms in interleukin 1 beta and interleukin 1 receptor antagonist associated with tumor recurrence in stage II colon cancer

scientific article

Prediction of cardiovascular disease among hematopoietic cell transplantation survivors

scientific article published on 01 July 2018

Predictive value of TLR7 polymorphism for cetuximab-based chemotherapy in patients with metastatic colorectal cancer

scientific article

Primary tumor location as a prognostic factor in metastatic colorectal cancer.

scientific article

Prognostic impact of FOXF1 polymorphisms in gastric cancer patients

scientific article published on 11 April 2017

Prospective study of EGFR intron 1 (CA)n repeats variants as predictors of benefit from cetuximab and irinotecan in chemo-refractory metastatic colorectal cancer (mCRC) patients

scientific article

Prospective validation of candidate SNPs of VEGF/VEGFR pathway in metastatic colorectal cancer patients treated with first-line FOLFIRI plus bevacizumab

scientific article

Reply to J. Zhang et al

scientific article published on 01 February 2013

Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients

scientific article

Sex differences in the predictive power of the molecular prognostic factor HER2/neu in patients with non-small-cell lung cancer

scientific article published in March 2006

Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial

scientific article published on 30 June 2020

Single nucleotide polymorphisms in AREG and EREG are prognostic biomarkers in locally advanced gastric cancer patients after surgery with curative intent.

scientific article

Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial.

scientific article published on 10 May 2017

Tandem repeat variation near the HIC1 (hypermethylated in cancer 1) promoter predicts outcome of oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.

scientific article published on 14 July 2017

The CXCR2 antagonist, SCH-527123, shows antitumor activity and sensitizes cells to oxaliplatin in preclinical colon cancer models

scientific article

The Cyclin D1 (CCND1) A870G polymorphism predicts clinical outcome to lapatinib and capecitabine in HER2-positive metastatic breast cancer

scientific article

The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy.

scientific article published on 9 April 2013

The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival

scientific article

Thymidylate synthase haplotype is associated with tumor recurrence in stage II and stage III colon cancer

scientific article published in February 2008

Timeliness of adjuvant chemotherapy for stage III adenocarcinoma of the colon: a measure of quality of care

scientific article published in December 2013

Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women

scientific article published in March 2002

Variable risk of second primary malignancy in multiple myeloma patients of different ethnic subgroups.

scientific article

Variations in genes involved in dormancy associated with outcome in patients with resected colorectal liver metastases

scientific article published on 8 May 2015

Variations in genes involved in immune response checkpoints and association with outcomes in patients with resected colorectal liver metastases

scientific article published on 10 March 2015

Variations in genes regulating tumor-associated macrophages (TAMs) to predict outcomes of bevacizumab-based treatment in patients with metastatic colorectal cancer: results from TRIBE and FIRE3 trials.

scientific article

List of works by Dongyun Yang

A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials

A phase I/II trial of vorinostat in combination with 5-fluorouracil in patients with metastatic colorectal cancer who previously failed 5-FU-based chemotherapy

ABCB1, SLCO1B1 and UGT1A1 gene polymorphisms are associated with toxicity in metastatic colorectal cancer patients treated with first-line irinotecan

AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth

An individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrence

Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence.

Association of variants in genes encoding for macrophage-related functions with clinical outcome in patients with locoregional gastric cancer.

Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials.

Biomarkers for Cetuximab-Based Neoadjuvant Radiochemotherapy in Locally Advanced Rectal Cancer

CXCR4 polymorphism predicts progression-free survival in metastatic colorectal cancer patients treated with first-line bevacizumab-based chemotherapy

Cell cycle regulators are critical for maintaining the differentiation potential and immaturity in adipogenesis of adipose-derived stem cells

Clinical Significance of TLR1 I602S Polymorphism for Patients with Metastatic Colorectal Cancer Treated with FOLFIRI plus Bevacizumab

Clinical relevance of EMT and stem-like gene expression in circulating tumor cells of metastatic colorectal cancer patients.

Combined assessment of EGFR-related molecules to predict outcome of 1st-line cetuximab-containing chemotherapy for metastatic colorectal cancer

Common cancer stem cell gene variants predict colon cancer recurrence.

Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab

Cytokeratin-20 and Survivin-Expressing Circulating Tumor Cells Predict Survival in Metastatic Colorectal Cancer Patients by a Combined Immunomagnetic qRT-PCR Approach

Drug abuse prevention program development. Results among Latino and non-Latino white adolescents

Expression of Genes Involved in Vascular Morphogenesis and Maturation Predicts Efficacy of Bevacizumab-Based Chemotherapy in Patients Undergoing Liver Resection.

FCGR polymorphisms and cetuximab efficacy in chemorefractory metastatic colorectal cancer: an international consortium study.

GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.

Gender-related survival differences associated with EGFR polymorphisms in metastatic colon cancer

Gender-related survival differences associated with polymorphic variants of estrogen receptor-β (ERβ) in patients with metastatic colon cancer.

Gender-specific genomic profiling in metastatic colorectal cancer patients treated with 5-fluorouracil and oxaliplatin.

Gender-specific profiling in SCN1A polymorphisms and time-to-recurrence in patients with stage II/III colorectal cancer treated with adjuvant 5-fluoruracil chemotherapy.

Gene expression in tumor-adjacent normal tissue is associated with recurrence in patients with rectal cancer treated with adjuvant chemoradiation

Gene expression levels of epidermal growth factor receptor, survivin, and vascular endothelial growth factor as molecular markers of lymph node involvement in patients with locally advanced rectal cancer

Generation of a concise gene panel for outcome prediction in urinary bladder cancer

Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer.

Genetic variants associated with colorectal brain metastases susceptibility and survival.

Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer.

Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer

Genetic variations in angiogenesis pathway genes associated with clinical outcome in localized gastric adenocarcinoma.

Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus

Genetic variations in angiopoietin and pericyte pathways and clinical outcome in patients with resected colorectal liver metastases.

Genetic variations in immunomodulatory pathways to predict survival in patients with locoregional gastric cancer.

Genomic profiling associated with recurrence in patients with rectal cancer treated with chemoradiation.

Germline Polymorphisms in Genes Involved in the IGF1 Pathway Predict Efficacy of Cetuximab in Wild-type KRAS mCRC Patients ⬇️

Germline polymorphisms in genes involved in the CD44 signaling pathway are associated with clinical outcome in localized gastric adenocarcinoma ⬇️

Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer.

Impact of access to NCI- and NCCN-designated cancer centers on outcomes for multiple myeloma patients: A SEER registry analysis

Impact of sex on the survival of patients with hepatocellular carcinoma: a Surveillance, Epidemiology, and End Results analysis.

Impact of sex, age, and ethnicity/race on the survival of patients with rectal cancer in the United States from 1988 to 2012.

Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagus.

Influence of sex on the survival of patients with esophageal cancer.

Insulin-like growth factor receptor polymorphism defines clinical outcome in estrogen receptor-positive breast cancer patients treated with tamoxifen.

Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer

Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis.

Interleukin-8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models.

Intratumoral COX-2 gene expression is a predictive factor for colorectal cancer response to fluoropyrimidine-based chemotherapy

Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).

Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer.

Metastatic Colorectal Cancer in Hispanics: Treatment Outcomes in a Treated Population

Molecular determinants of irinotecan efficacy.

Outcome disparities among ethnic subgroups of Waldenström's macroglobulinemia: a population-based study

Outcome disparities in multiple myeloma: a SEER-based comparative analysis of ethnic subgroups

Persistent Disparities Among Patients With T-Cell Non-Hodgkin Lymphomas and B-Cell Diffuse Large Cell Lymphomas Over 40 Years: A SEER Database Review.

Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer

Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia

Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer

Physical activity and breast cancer risk among Asian-American women in Los Angeles: a case-control study

Plastin polymorphisms predict gender- and stage-specific colon cancer recurrence after adjuvant chemotherapy.

Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer

Polymorphisms in cyclooxygenase-2 and epidermal growth factor receptor are associated with progression-free survival independent of K-ras in metastatic colorectal cancer patients treated with single-agent cetuximab

Polymorphisms in immunoregulatory genes, smoky coal exposure and lung cancer risk in Xuan Wei, China.

Polymorphisms in interleukin 1 beta and interleukin 1 receptor antagonist associated with tumor recurrence in stage II colon cancer

Prediction of cardiovascular disease among hematopoietic cell transplantation survivors

Predictive value of TLR7 polymorphism for cetuximab-based chemotherapy in patients with metastatic colorectal cancer

Primary tumor location as a prognostic factor in metastatic colorectal cancer.

Prognostic impact of FOXF1 polymorphisms in gastric cancer patients

Prospective study of EGFR intron 1 (CA)n repeats variants as predictors of benefit from cetuximab and irinotecan in chemo-refractory metastatic colorectal cancer (mCRC) patients

Prospective validation of candidate SNPs of VEGF/VEGFR pathway in metastatic colorectal cancer patients treated with first-line FOLFIRI plus bevacizumab

Reply to J. Zhang et al

Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients

Sex differences in the predictive power of the molecular prognostic factor HER2/neu in patients with non-small-cell lung cancer

Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial

Single nucleotide polymorphisms in AREG and EREG are prognostic biomarkers in locally advanced gastric cancer patients after surgery with curative intent.

Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial.

Tandem repeat variation near the HIC1 (hypermethylated in cancer 1) promoter predicts outcome of oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.