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List of works by Nicolas Legrand

A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4+ T-cell depletion

scientific article published on 30 May 2012

A sensitive cell-based assay to measure the doxycycline concentration in biological samples.

scientific article

AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway

scientific article

Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection

scientific article

Autonomous and extrinsic regulation of thymopoiesis in human immune system (HIS) mice

scientific article

Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo

scientific article

CD8+ T Lymphocytes in Double αβ TCR Transgenic Mice. I. TCR Expression and Thymus Selection in the Absence or in the Presence of Self-Antigen ⬇️

scientific article published on 01 December 2001

CD8+ T Lymphocytes in Double αβ TCR Transgenic Mice. II. Competitive Fitness of Dual αβ TCR CD8+ T Lymphocytes in the Peripheral Pools ⬇️

scientific article published on 01 December 2001

Efficient CRM197-mediated drug targeting to monocytes

scientific article published on October 2011

Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)gammac(-/-)) mouse model

scientific article

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

scientific article

Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

scientific article (publication date: 4 October 2010)

High-throughput identification of antigen-specific TCRs by TCR gene capture

scientific article

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

scientific article published on July 2009

IL-15 transpresentation promotes both human T-cell reconstitution and T-cell–dependent antibody responses in vivo ⬇️

scientific article published on March 28, 2011

IL-7 Enhances Thymic Human T Cell Development in "Human Immune System" Rag2-/-IL-2R c-/- Mice without Affecting Peripheral T Cell Homeostasis

article

Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells

scientific article

Preclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV-1

scientific article published on 03 September 2013

Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice

scientific article published on 28 August 2009

Stem Cell Factor Consistently Improves Thymopoiesis after Experimental Transplantation of Murine or Human Hematopoietic Stem Cells in Immunodeficient Mice ⬇️

scientific article published on August 22, 2011

Thymic stromal lymphopoietin induces early human B-cell proliferation and differentiation

scientific article published in April 2010

Transient accumulation of human mature thymocytes and regulatory T cells with CD28 superagonist in "human immune system" Rag2(-/-)gammac(-/-) mice

scientific article published on 02 March 2006

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