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List of works by Richie Soong

A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting

scientific article published on 08 October 2009

A warfarin-dosing model in Asians that uses single-nucleotide polymorphisms in vitamin K epoxide reductase complex and cytochrome P450 2C9.

scientific article published in October 2006

ADPRT Val762Ala and XRCC1 Arg194Trp Polymorphisms and Risk of Gastric Cancer in Sichuan of China ⬇️

scientific article published on January 1, 2012

Advances and challenges in fluoropyrimidine pharmacogenomics and pharmacogenetics.

scientific article

An improved quality control for bisulfite-PCR-based DNA methylation analysis: cycle threshold value

scientific article

Association of the IL-1B +3954 C/T polymorphism with the risk of gastric cancer in a population in Western China.

scientific article

BRAF mutation is associated with the CpG island methylator phenotype in colorectal cancer from young patients

scientific article published on 07 September 2008

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

scientific article published on 28 April 2008

CD133 expression predicts for non-response to chemotherapy in colorectal cancer

scientific article published on 15 January 2010

CYP3A5*3 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients

scientific article published on 17 December 2013

Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?

scientific article published on 26 June 2012

Clinical and therapeutic relevance of PIM1 kinase in gastric cancer

scientific article published on 13 October 2011

Clinical potential of DNA methylation in gastric cancer: a meta-analysis

scientific article

Clonal characterization of sporadic cribriform-morular variant of papillary thyroid carcinoma by laser microdissection-based APC mutation analysis

scientific article

Comparison of the pharmacokinetics and pharmacodynamics of S-1 between Caucasian and East Asian patients

scientific article published on 10 December 2010

Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features

scientific article

Computer-assisted pathological immunohistochemistry scoring is more time-effective than conventional scoring, but provides no analytical advantage

scientific article published on 01 March 2010

Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas

scientific article published on 01 October 1996

Correlation between epidermal growth factor receptor mutations and expression of female hormone receptors in East-Asian lung adenocarcinomas.

scientific article published in January 2010

Correlation of aldo-ketoreductase (AKR) 1C3 genetic variant with doxorubicin pharmacodynamics in Asian breast cancer patients.

scientific article published on June 2013

DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach.

scientific article

Dasatinib induces a response in malignant thymoma

scientific article published in December 2006

Dedifferentiated liposarcoma with unusual kaposiform morphology and whorl formation masquerading As Kaposi's sarcoma: diagnostically challenging case confirmed by cytogenetic and TP53 mutation analysis.

scientific article published on 14 January 2013

Dedifferentiated solitary fibrous tumour of the nasal cavity: the first case reported with molecular characterization of a TP53 mutation

scientific article published on 25 October 2011

Deep whole-genome sequencing of 100 southeast Asian Malays

scientific article published on 3 January 2013

Denaturing high performance liquid chromatography for the detection of microsatellite instability using bethesda and pentaplex marker panels.

scientific article

Detection of BRAF V600E mutation by pyrosequencing

scientific article

Detection of epidermal growth factor receptor variations by partially denaturing HPLC.

scientific article

Detection of p53 gene mutation by rapid PCR-SSCP and its association with poor survival in breast cancer

scientific article published on 01 December 1997

Determination of a molecular signature of acute T-cell-mediated renal allograft rejection using quantitative real-time RT-PCR of 45 genes on a low density array.

scientific article

Differences in outcome and toxicity between Asian and caucasian patients with lung cancer treated with systemic therapy.

scientific article published on April 2012

Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients

scientific article

E1A-F is overexpressed early in human colorectal neoplasia and associated with cyclooxygenase-2 and matrix metalloproteinase-7.

scientific article

Effect of blood sample handling and reverse transcriptase-polymerase chain reaction assay sensitivity on detection of CK20 expression in healthy donor blood

scientific article published on 01 June 2002

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.

scientific article

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

scientific article

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.

scientific article

Ethnic differences in survival outcome in patients with advanced stage non-small cell lung cancer: results of a meta-analysis of randomized controlled trials.

scientific article published on June 2011

Evidence for disease control with erlotinib after gefitinib failure in typical gefitinib-sensitive Asian patients with non-small cell lung cancer

scientific article published in April 2008

Exome sequencing: dual role as a discovery and diagnostic tool

scientific article published on January 2012

Exome versus transcriptome sequencing in identifying coding region variants

scientific article published on April 2012

Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study.

scientific article published on 8 March 2006

GBSA: a comprehensive software for analysing whole genome bisulfite sequencing data.

scientific article

Gastric carcinomas with microsatellite instability: clinical features and mutations to the TGF-beta type II receptor, IGFII receptor, and BAX genes

scientific article published on 01 March 1999

Gene discovery in familial cancer syndromes by exome sequencing: prospects for the elucidation of familial colorectal cancer type X.

scientific article

Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study

scientific article

Human genetics and genomics a decade after the release of the draft sequence of the human genome

scientific article published in October 2011

Identification of potentially useful combinations of epidermal growth factor receptor tyrosine kinase antagonists with conventional cytotoxic agents using median effect analysis

scientific article published on September 2006

Immunotherapy in the treatment of non-small cell lung cancer

scientific article

Impact of sample heterogeneity on methylation analysis

scientific article published on 01 December 2010

Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics.

scientific article

Improved indicators for assessing the reliability of detection and quantification by kinetic PCR

scientific article published on 01 June 2003

Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype.

scientific article

Insights into the genetic structure and diversity of 38 South Asian Indians from deep whole-genome sequencing

scientific article

Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population

scientific article published in March 2006

Interleukin-10 Gene Promoter Polymorphisms and Risk of Gastric Cancer in a Chinese Population: Single Nucleotide and Haplotype Analyses ⬇️

scientific article published on January 1, 2013

KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma.

scientific article

KRAS mutation analysis in a complex molecular diagnostic referral practice: the need for test redundancy

scientific article published on 01 December 2012

Localized sclerotic bone response demonstrated reduced nanomechanical creep properties.

scientific article

Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.

scientific article

Lymphocytic follicles and aggregates are a determinant of mucosal damage and duration of diarrhea

scientific article published in January 2013

Meta-analysis of genetic polymorphisms and gastric cancer risk: variability in associations according to race

scientific article published on 15 April 2009

MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer

scientific article

Molecular characterization of dedifferentiated mucoepidermoid carcinoma of the trachea using laser microdissection-based TP53 mutation analysis

scientific article published on 01 October 2009

Molecular gene expression signature patterns for gastric cancer diagnosis

scientific article published on 13 June 2007

Mutation of the transforming growth factor-beta type II receptor gene in right-sided colorectal cancer: relationship to clinicopathological features and genetic alterations

scientific article

Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil–based chemotherapy.

scientific article

Patz1 regulates embryonic stem cell identity.

scientific article published on 25 March 2014

Pharmacodynamic effects of seliciclib, an orally administered cell cycle modulator, in undifferentiated nasopharyngeal cancer

scientific article published in February 2009

Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells.

scientific article

Phase II evaluation of docetaxel-modulated capecitabine in previously treated patients with non-small cell lung cancer

scientific article

Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation

scientific article published on 17 September 2013

Polymorphisms of XRCC1 and ADPRT Genes and Risk of Noncardia Gastric Cancer in a Chinese Population: a Case-control Study ⬇️

scientific article published on 01 January 2012

Postoperative serum methylation levels of TAC1 and SEPT9 are independent predictors of recurrence and survival of patients with colorectal cancer

scientific article

Primary mucinous adenocarcinoma of the epididymis: report of a rare case with molecular genetic characterization including mutation analysis of the TP53 gene

scientific article published on 01 April 2015

Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation

scientific article published on 01 October 2000

Protein arginine methyltransferase 6 regulates embryonic stem cell identity

scientific article published on 8 May 2012

Quantitative detection of cytokeratin 20 mRNA expression in bladder carcinoma by real-time reverse transcriptase-polymerase chain reaction

scientific article published in July 2004

RUNX3 downregulation in human lung adenocarcinoma is independent of p53, EGFR or KRAS status.

scientific article

RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression.

scientific article

RUNX3 inactivation in colorectal polyps arising through different pathways of colonic carcinogenesis

scientific article published on 27 January 2009

RUNX3 protein is overexpressed in human basal cell carcinomas

scientific article

Response to a novel multitargeted tyrosine kinase inhibitor pazopanib in metastatic Merkel cell carcinoma.

scientific article published on 29 June 2009

Simultaneous detection of variable number tandem repeats, single nucleotide polymorphisms, and allelic imbalance in the thymidylate synthase gene enhancer region using denaturing high-performance liquid chromatography

scientific article

Studying the epigenome using next generation sequencing

scientific article

TRARESA: a tissue microarray-based hospital system for biomarker validation and discovery.

scientific article published on August 2008

Targeting ROS1 with anaplastic lymphoma kinase inhibitors: a promising therapeutic strategy for a newly defined molecular subset of non-small-cell lung cancer.

scientific article

Technological advances in DNA sequence enrichment and sequencing for germline genetic diagnosis

scientific article published on March 2012

The common molecular genetic alterations in Dukes' B and C colorectal carcinomas are not short-term prognostic indicators of survival

scientific article published on 01 December 1994

The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome.

scientific article published on 17 February 2009

The positive impact of cytological specimens for EGFR mutation testing in non-small cell lung cancer: a single South East Asian laboratory's analysis of 670 cases.

scientific article

The topography of DNA methylation in the non-neoplastic colonic mucosa surrounding colorectal cancers

scientific article published on 21 August 2012

Thrombomodulin expression in gastrointestinal stromal tumours (GISTs): a novel finding with diagnostic implications

scientific article published on 01 January 2009

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

scientific article

Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer

scientific article published in June 2005

Use of intraoperative cell-salvage for autologous blood transfusions in metastatic spine tumour surgery: a systematic review.

scientific article published on January 2014

Whole-genome reconstruction and mutational signatures in gastric cancer.

scientific article

p53 accumulation and mutation are prognostic indicators of poor survival in human gastric carcinoma

scientific article published on 01 June 1996

p53 protein overexpression and gene mutation in mixed Müllerian tumors of the uterus

scientific article published on 01 January 1999

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