List of works - Eric P. Bennett

A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation

scientific article published in September 1996

A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3

scientific article published in December 1997

A glycogene mutation map for discovery of diseases of glycosylation

scientific article

A novel monoclonal antibody to a defined peptide epitope in MUC16.

scientific article published on 22 July 2015

A novel α-N-acetylgalactosaminidase family with an NAD+-dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens

A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing

scientific article

A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation

scientific article published on 01 August 2019

A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome.

scientific article published on 5 January 2018

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

scientific article published on 18 June 2019

An acetylation site in lectin domain modulates the biological activity of polypeptide GalNAc-transferase-2.

scientific article published in January 2013

Bacterial glycosidases for the production of universal red blood cells

scientific article

Biosynthetic basis of incompatible histo-blood group A antigen expression: anti-A transferase antibodies reactive with gastric cancer tissue of type O individuals

scientific article published on 01 November 1993

Blood group ABO-related glycosylation of urothelial cell lines: immunocytological, enzymatic, and genetic characterization.

scientific article published on May 1994

CDX2 homeoprotein is involved in the regulation of ST6GalNAc-I gene in intestinal metaplasia.

scientific article published on 13 April 2015

Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes

scientific article published on 2 February 2010

Carbohydrates of the cell surface: molecular aspects of glycosyltransferases and their genes

scientific article published on January 1, 1992

Catalytic and glycan-binding abilities of ppGalNAc-T2 are regulated by acetylation

scientific article published on 27 May 2011

Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation

scientific article published on 11 August 2007

Characterization of a Panel of Monoclonal Antibodies Using GalNAc Glycosylated Peptides and Recombinant MUC1

scientific article published on 01 January 1998

Characterization of binding epitopes of CA125 monoclonal antibodies.

scientific article published on 4 June 2014

Characterization of the histo-blood group O(2) gene and its protein product

scientific article published on January 2000

Cloning of a Human UDP-N-Acetyl-α-d-Galactosamine:PolypeptideN-Acetylgalactosaminyltransferase That Complements Other GalNAc-Transferases in Complete O-Glycosylation of the MUC1 Tandem Repeat ⬇️

scientific article published on November 13, 1998

Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis

scientific article

Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4

scientific article

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family ⬇️

scientific article published on December 18, 2011

De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium. ⬇️

scientific article published on 29 November 2017

Deconstruction of O-glycosylation--GalNAc-T isoforms direct distinct subsets of the O-glycoproteome.

scientific article

Dynamics of Indel Profiles Induced by Various CRISPR/Cas9 Delivery Methods

scientific article published on 6 November 2017

Elucidation of the sugar recognition ability of the lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 by using unnatural glycopeptide substrates

scientific article

Engineered CHO cells for production of diverse, homogeneous glycoproteins.

scientific article published on 20 July 2015

Engineering mammalian mucin-type O-glycosylation in plants.

scientific article published on 14 February 2012

Enhanced mass spectrometric mapping of the human GalNAc-type O-glycoproteome with SimpleCells

scientific article published on 11 February 2013

Erratum: Corrigendum: Mining the O-glycoproteome using zinc-finger nuclease–glycoengineered SimpleCell lines

scholarly article published in Nature Methods

Evaluation of histo-blood group ABO genotyping in a Danish population: frequency of a novel O allele defined as O2.

scientific article published in January 1994

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

scientific article published on 30 April 2019

Expression of the -Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa

scholarly article by Marie B Nygaard published in September 2018

Expression of three UDP-N-acetyl-alpha-D-galactosamine:polypeptide GalNAc N-acetylgalactosaminyltransferases in adenocarcinoma cell lines

scientific article published on November 1997

Extrinsic Functions of Lectin Domains in O-N-Acetylgalactosamine Glycan Biosynthesis

scientific article published on 13 October 2016

Fast and Quantitative Identification of Ex Vivo Precise Genome Targeting-Induced Indel Events by IDAA

scientific article published on 01 January 2019

Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila

scientific article

Functional control of polypeptide GalNAc-transferase 3 through an acetylation site in the C-terminal lectin domain

scientific article published on 27 June 2017

Generation of Monoclonal Antibodies to Native Active Human Glycosyltransferases ⬇️

scientific article published on January 1, 2013

Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

scientific article published on 16 February 2017

Genomic Cloning of the Human Histo-Blood Group ABO Locus

scientific article published on 01 June 1995

Genomic cloning of the human histo-blood group ABO locus.

scientific article

Genomic organization and chromosomal localization of three members of the UDP-N-acetylgalactosamine: polypeptide N-acetylgalactosaminyltransferase family

scientific article

Glycan bioengineering in immunogen design for tumor T antigen immunotargeting.

scientific article

Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases.

scientific article published on 22 March 2018

HLA-E polymorphism in patients with recurrent spontaneous abortion

scientific article published in December 1998

High efficacy full allelic CRISPR/Cas9 gene editing in tetraploid potato

scientific article published on 27 November 2019

High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs

scientific article

Histo-blood group ABO antigen in oral potentially malignant lesions and squamous cell carcinoma--genotypic and phenotypic characterization.

scientific article

Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability

scientific article published on April 2013

IDDM7 links to insulin-dependent diabetes mellitus in Danish multiplex families but linkage is not explained by novel polymorphisms in the candidate gene GALNT3. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Ge

scientific article

INDEL detection, the 'Achilles heel' of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

scientific article published on 10 November 2020

Identification of a GH110 subfamily of alpha 1,3-galactosidases: novel enzymes for removal of the alpha 3Gal xenotransplantation antigen.

scientific article

Immature truncated O-glycophenotype of cancer directly induces oncogenic features

scientific article

Immunolocalisation of members of the polypeptide N-acetylgalactosaminyl transferase (ppGalNAc-T) family is consistent with biologically relevant altered cell surface glycosylation in breast cancer

scientific article published on 19 April 2007

Improved CRISPR/Cas9 gene editing by fluorescence activated cell sorting of green fluorescence protein tagged protoplasts.

scientific article published on 17 June 2019

Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2

scientific article published in Scientific Reports

Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents.

scientific article published on August 2016

Low density lipoprotein receptor class A repeats are O-glycosylated in linker regions

scientific article

MUC1 gene polymorphism and gastric cancer--an epidemiological study.

scientific article published in January 1997

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

scientific article published on 9 October 2011

Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteins

scientific article published on 07 October 2013

Molecular genetics of ABO histo-blood groups

scientific article published on January 1994

Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.

scientific article published on 26 November 2015

O-linked glycosylation of the mucin domain of the herpes simplex virus type 1-specific glycoprotein gC-1 is temporally regulated in a seed-and-spread manner

scientific article

Oral candidosis in lichen planus: the diagnostic approach is of major therapeutic importance

scientific article published on 15 June 2012

Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expression

scientific article

Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression.

scientific article published on 4 May 2017

Precision genome editing: a small revolution for glycobiology.

scientific article published on 26 May 2014

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

scientific article published on 12 April 2013

Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

scientific article

Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis

scientific article

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

scientific article published in Journal of Biological Chemistry

Purification and cDNA Cloning of a Human UDP-N-acetyl-α- D-galactosamine:polypeptide N-Acetylgalactosaminyltransferase ⬇️

scientific article published on October 13, 1995

Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.

scientific article published on 27 April 2010

Seromic profiling of colorectal cancer patients with novel glycopeptide microarray

scientific article published on 12 January 2011

Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

scientific article published on 20 March 2018

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

scientific article published on April 2013

Structural Analysis of Peptide Substrates for Mucin-Type O-Glycosylation†

article

Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts.

scientific article published on 30 March 2018

Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3

scientific article

The GAGOme: a cell-based library of displayed glycosaminoglycans

scientific article published on 13 August 2018

The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2

scientific article published on 05 July 2018

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

scientific article published on 30 April 2019

The lectin domain of UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-T4 directs its glycopeptide specificities

scientific article published on December 2000

The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation

scientific article published on 10 January 2007

The origin and function of platelet glycosyltransferases ⬇️

scientific article published on May 21, 2012

Thiogalactopyranosides are Resistant to Hydrolysis by α‐Galactosidases ⬇️

scientific article published on June 27, 2012

Toward stable genetic engineering of human O-glycosylation in plants

article

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

scientific article published on 01 September 2007

cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D-galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3

scientific article

List of works by Eric P. Bennett

A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation

A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3

A glycogene mutation map for discovery of diseases of glycosylation

A novel monoclonal antibody to a defined peptide epitope in MUC16.

A novel α-N-acetylgalactosaminidase family with an NAD+-dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens

A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing

A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation

A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome.

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

An acetylation site in lectin domain modulates the biological activity of polypeptide GalNAc-transferase-2.

Bacterial glycosidases for the production of universal red blood cells

Biosynthetic basis of incompatible histo-blood group A antigen expression: anti-A transferase antibodies reactive with gastric cancer tissue of type O individuals

Blood group ABO-related glycosylation of urothelial cell lines: immunocytological, enzymatic, and genetic characterization.

CDX2 homeoprotein is involved in the regulation of ST6GalNAc-I gene in intestinal metaplasia.

Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes

Carbohydrates of the cell surface: molecular aspects of glycosyltransferases and their genes

Catalytic and glycan-binding abilities of ppGalNAc-T2 are regulated by acetylation

Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation

Characterization of a Panel of Monoclonal Antibodies Using GalNAc Glycosylated Peptides and Recombinant MUC1

Characterization of binding epitopes of CA125 monoclonal antibodies.

Characterization of the histo-blood group O(2) gene and its protein product

Cloning of a Human UDP-N-Acetyl-α-d-Galactosamine:PolypeptideN-Acetylgalactosaminyltransferase That Complements Other GalNAc-Transferases in Complete O-Glycosylation of the MUC1 Tandem Repeat ⬇️

Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis

Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family ⬇️

De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium. ⬇️

Deconstruction of O-glycosylation--GalNAc-T isoforms direct distinct subsets of the O-glycoproteome.

Dynamics of Indel Profiles Induced by Various CRISPR/Cas9 Delivery Methods

Elucidation of the sugar recognition ability of the lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 by using unnatural glycopeptide substrates

Engineered CHO cells for production of diverse, homogeneous glycoproteins.

Engineering mammalian mucin-type O-glycosylation in plants.

Enhanced mass spectrometric mapping of the human GalNAc-type O-glycoproteome with SimpleCells

Erratum: Corrigendum: Mining the O-glycoproteome using zinc-finger nuclease–glycoengineered SimpleCell lines

Evaluation of histo-blood group ABO genotyping in a Danish population: frequency of a novel O allele defined as O2.

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

Expression of the -Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa

Expression of three UDP-N-acetyl-alpha-D-galactosamine:polypeptide GalNAc N-acetylgalactosaminyltransferases in adenocarcinoma cell lines

Extrinsic Functions of Lectin Domains in O-N-Acetylgalactosamine Glycan Biosynthesis

Fast and Quantitative Identification of Ex Vivo Precise Genome Targeting-Induced Indel Events by IDAA

Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila

Functional control of polypeptide GalNAc-transferase 3 through an acetylation site in the C-terminal lectin domain

Generation of Monoclonal Antibodies to Native Active Human Glycosyltransferases ⬇️

Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

Genomic Cloning of the Human Histo-Blood Group ABO Locus

Genomic cloning of the human histo-blood group ABO locus.

Genomic organization and chromosomal localization of three members of the UDP-N-acetylgalactosamine: polypeptide N-acetylgalactosaminyltransferase family

Glycan bioengineering in immunogen design for tumor T antigen immunotargeting.

Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases.

HLA-E polymorphism in patients with recurrent spontaneous abortion

High efficacy full allelic CRISPR/Cas9 gene editing in tetraploid potato

High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs

Histo-blood group ABO antigen in oral potentially malignant lesions and squamous cell carcinoma--genotypic and phenotypic characterization.

Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability

IDDM7 links to insulin-dependent diabetes mellitus in Danish multiplex families but linkage is not explained by novel polymorphisms in the candidate gene GALNT3. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Ge

INDEL detection, the 'Achilles heel' of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

Identification of a GH110 subfamily of alpha 1,3-galactosidases: novel enzymes for removal of the alpha 3Gal xenotransplantation antigen.

Immature truncated O-glycophenotype of cancer directly induces oncogenic features

Immunolocalisation of members of the polypeptide N-acetylgalactosaminyl transferase (ppGalNAc-T) family is consistent with biologically relevant altered cell surface glycosylation in breast cancer

Improved CRISPR/Cas9 gene editing by fluorescence activated cell sorting of green fluorescence protein tagged protoplasts.

Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2

Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents.

Low density lipoprotein receptor class A repeats are O-glycosylated in linker regions

MUC1 gene polymorphism and gastric cancer--an epidemiological study.

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteins

Molecular genetics of ABO histo-blood groups

Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.

O-linked glycosylation of the mucin domain of the herpes simplex virus type 1-specific glycoprotein gC-1 is temporally regulated in a seed-and-spread manner

Oral candidosis in lichen planus: the diagnostic approach is of major therapeutic importance

Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expression

Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression.

Precision genome editing: a small revolution for glycobiology.

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

Purification and cDNA Cloning of a Human UDP-N-acetyl-α- D-galactosamine:polypeptide N-Acetylgalactosaminyltransferase ⬇️

Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.

Seromic profiling of colorectal cancer patients with novel glycopeptide microarray